ISSN: 1838-7640Theranostics
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Volume 15 (1); 2025
Research Papers
CD63 as novel target for nanoemulsion-based 19F MRI imaging and drug delivery to activated cardiac fibroblasts
Arlen Aurora Euan Martínez, Ann Kathrin Bergmann, Frederik Tellkamp, Stephan Schott-Verdugo, Pascal Bouvain, Julia Steinhausen, Jasmin Bahr, Vivien Kmietczyk, Maja Bencun, Ulrich Flögel, Jörg H. W. Distler, Marcus Krueger, Mirko Völkers, Constantin Czekelius, Holger Gohlke, Sebastian Temme, Julia Hesse, Jürgen Schrader
Theranostics 2025; 15(1): 1-18. doi:10.7150/thno.96990
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CXCR4-directed endoradiotherapy with [177Lu]Pentixather added to total body irradiation for myeloablative conditioning in patients with relapsed/refractory acute myeloid leukemia
Krischan Braitsch, Theo Lorenzini, Maike Hefter, Katrin Koch, Katharina Nickel, Jan C Peeken, Katharina S Götze, Wolfgang Weber, Anne Allmann, Calogero D'Alessandria, Julia Brosch-Lenz, Florian Bassermann, Martina Rudelius, Mareike Verbeek, Matthias Eiber, Peter Herhaus
Theranostics 2025; 15(1): 19-29. doi:10.7150/thno.101215
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Revolutionizing drug delivery: low-intensity pulsed ultrasound (LIPUS)-driven deep penetration into hypoxic tumor microenvironments of cholangiocarcinoma
Sera Hong, Jaihwan Kim, Gujin Chung, Donghyuk Lee, Joon Myong Song
Theranostics 2025; 15(1): 30-51. doi:10.7150/thno.99981
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Optical molecular imaging in oral- and oropharyngeal squamous cell carcinoma using a novel uPAR-targeting near-infrared imaging agent FG001 (ICG-glu-glu-AE105): An explorative phase II clinical trial
Amanda Oester Andersen, Anders Christensen, Karina Straede, Mads Lawaetz, Christoffer Holst Hahn, Nicklas Rubek, Irene Wessel, Giedrius Lelkaitis, Katalin Kiss, Natasja Paaske, Anne Poulsen, Christian von Buchwald, Andreas Kjaer
Theranostics 2025; 15(1): 52-67. doi:10.7150/thno.100042
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Integrating oxygen-boosted sonodynamic therapy and ferroptosis via engineered exosomes for effective cancer treatment
Mingbo Wu, Zhanlin Zhang, Dong Li, Xiaomiao Ruan, Jingwen Yang, Siyi Chen, Xin Li, Wenwu Ling
Theranostics 2025; 15(1): 68-85. doi:10.7150/thno.102977
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iRGD-TRP-PK1-modified red blood cell membrane vesicles as a new chemotherapeutic drug delivery and targeting system in head and neck cancer
Suwen Bai, Zunyun Wang, Yuxin Zhang, Yunyun Yang, Yuan Wei, Yumei Luo, Minghua Wang, Bing Shen, Wei He, Zhenye Yang, Hui Hui, Juan Du
Theranostics 2025; 15(1): 86-102. doi:10.7150/thno.99481
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Development of dual aptamers-functionalized c-MET PROTAC degraders for targeted therapy of osteosarcoma
Xuekun Fu, Jie Huang, Xinxin Chen, Duoli Xie, Hongzhen Chen, Zhijian Liang, Zhuqian Wang, Yiying Liang, Aiping Lu, Chao Liang
Theranostics 2025; 15(1): 103-121. doi:10.7150/thno.99588
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18F-5-fluoro-aminosuberic acid PET/CT imaging of oxidative-stress features during the formation of DEN-induced rat hepatocellular carcinoma
Feng Xiong, Yilin Yang, Zhengru Han, Buchuan Zhang, Kijung Kwak, Pei Wang, Qiaorong Chen, Ziqiang Wang, Jingfei Yang, Xiaoyun Deng, Sijuan Zou, Zhuoli Zhang, Pengtao You, Bo Yu, Xiaohua Zhu
Theranostics 2025; 15(1): 141-154. doi:10.7150/thno.100467
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A H2S-activated NIR-II imaging probe for precise diagnosis and pathological evaluation of colorectal tumor
Yu Ji, Qinxian Huang, Qian Jia, Haohao Yan, Yajing Chi, Yuanyuan Jia, Chaoqiang Qiao, Yanbin Feng, Zuo Yang, Ruili Zhang, Zhongliang Wang
Theranostics 2025; 15(1): 189-201. doi:10.7150/thno.103999
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Big data analytics and scRNA-seq in human aortic aneurysms and dissections: role of endothelial MerTK
Shijie Liu, Jinzi Wu, Oishani Banerjee, Bingzhong Xue, Hang Shi, Zufeng Ding
Theranostics 2025; 15(1): 202-215. doi:10.7150/thno.103851
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Tumor immunomodulation by nanoparticle and focused ultrasound alters gut microbiome in a sexually dimorphic manner
Akansha Singh, Sri Vidhya Chandrasekar, Vishnu Thayil Valappil, Joy Scaria, Ashish Ranjan
Theranostics 2025; 15(1): 216-232. doi:10.7150/thno.99664
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First clinical utility of sensing Ultrasound Localization Microscopy (sULM): identifying renal pseudotumors
Sylvain Bodard, Louise Denis, Georges Chabouh, Dany Anglicheau, Olivier Hélénon, Jean-Michel Correas, Olivier Couture
Theranostics 2025; 15(1): 233-244. doi:10.7150/thno.100897
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Inhibiting autophagy selectively prunes dysfunctional tumor vessels and optimizes the tumor immune microenvironment
Wanting Hou, Chaoxin Xiao, Ruihan Zhou, Xiaohong Yao, Qin Chen, Tongtong Xu, Fujun Cao, Yulin Wang, Xiaoying Li, Ouying Yan, Xiaolin Ai, Cheng Yi, Dan Cao, Chengjian Zhao
Theranostics 2025; 15(1): 258-276. doi:10.7150/thno.98285
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A STING agonist prodrug reprograms tumor-associated macrophage to boost colorectal cancer immunotherapy
Aohua Deng, Renming Fan, Yongrui Hai, Junyan Zhuang, Bingjie Zhang, Xintong Lu, Wenhui Wang, Li Luo, Ge Bai, Lei Liang, Le Yang, Minggao Zhao, Gaofei Wei
Theranostics 2025; 15(1): 277-299. doi:10.7150/thno.101001
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Reviews
Optical coherence tomography (OCT) and OCT angiography: Technological development and applications in brain science
Luyao Yang, Pengyu Chen, Xiaofei Wen, Qingliang Zhao
Theranostics 2025; 15(1): 122-140. doi:10.7150/thno.97192
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Metabolism of cancer cells and immune cells in the initiation, progression, and metastasis of cancer
Mingxia Jiang, Huapan Fang, Huayu Tian
Theranostics 2025; 15(1): 155-188. doi:10.7150/thno.103376
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tRNA-derived small RNAs in disease immunity
Hongyuan Jia, Linling Zhang
Theranostics 2025; 15(1): 245-257. doi:10.7150/thno.102650
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Targeting cancer with precision: strategical insights into TCR-engineered T cell therapies
Pei Lin, Yunfan Lin, Zizhao Mai, Yucheng Zheng, Jiarong Zheng, Zihao Zhou, Xinyuan Zhao, Li Cui
Theranostics 2025; 15(1): 300-323. doi:10.7150/thno.104594
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Leveraging plant-derived nanovesicles for advanced nucleic acid-based gene therapy
Meihong Chai, Bowen Gao, Shihua Wang, Liping Zhang, Xing Pei, Baosen Yue, Xueyan Zhen, Mingzhen Zhang
Theranostics 2025; 15(1): 324-339. doi:10.7150/thno.104507
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