Online advance articles

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MAP3K3 Contributes to Myocardial Ischemia/Reperfusion Injury by Promoting Myeloid Cell Diapedesis through TAL1/JAM-A Pathway
Shiyu Hu, Jian Zhang, Jingpu Wang, Chenguang Li, Yiwen Wang, Jiayu Liang, Rong Huang, Jie Yang, Yang Gao, Yanan Qu, Hongbo Yang, Juying Qian, Wenwen Tang, Jiatian Cao, Feng Zhang, Junbo Ge
Theranostics 2025; doi:10.7150/thno.122130; in press
Author manuscript

Lipid nanoparticle-formulated DNA acts as a potent immune modulator for cancer immunotherapy through interferon signaling pathways
Hsin-Wei Chen, Chen-Yi Chiang, Ming-Shu Hsieh, Mei-Yu Chen, YuWen Tsai, Chang-Ling Lin, Chia-Wei Hsu, Guann-Yi Yu, Ming-Hsi Huang, Shih-Jen Liu
Theranostics 2025; doi:10.7150/thno.121364; accepted
Author manuscript

Targeting Efferocytosis for Tissue Regeneration: From Microenvironment Reprogramming to Clinical Translation
Yunzhu Li, Peiyu Li, Jiayi Song, Xue Zhang, Haitao Xiao, Ru Wang, Zhenyu Duan, Kui Luo, and Xuewen Xu
Theranostics 2025; doi:10.7150/thno.126081; accepted
Author manuscript

Verteporfin-Loaded Hydrogel targeting YAP-mediated MDSCs recruitment for the treatment of residual tumors after incomplete radiofrequency ablation
Jiawen Chen, Junfeng Liu, Xiaoting Zhang, Xi Li, Jinming Fan, Shengchao Zhao, Junbin Liu, Ke Zhang, and Bin Zhou
Theranostics 2025; doi:10.7150/thno.119377; accepted
Author manuscript

Self-boosting targeted anticancer therapy via cancer cell self-reprogramming with GGT-targeting oxidative stress nanoamplifiers
Soojin Kim, Suyeon Lee, Manseok Yang, Seungwon Jung, Nanhee Song, Nuri Kim, Hanui Jo, Seunga Lee, Chaihong Nah, Seong-Cheol Park, Dongwon Lee
Theranostics 2025; doi:10.7150/thno.120954; in press
Author manuscript

Glutathione-Depleting Photosensitizers for Tumor-Specific Imaging and Pyroptosis-Driven Photodynamic Therapy
Hui Yang, Yifei Yang, Zhengyumeng Zhu, Pei Chen, Jucai Gao, Yajun Lin, Qiang Wang, Fang Hu
Theranostics 2025; doi:10.7150/thno.124154; in press
Author manuscript

An Integrated Ultrasound-Guided Focused Ultrasound (USgFUS) System for Spatiotemporal Regulation of Thermal Gene Activation in Engineered Immune Cells
Stanislav Y. Emelianov, Jeungyoon Lee, Melissa Cadena, Myeongsoo Kim, Seoyoon Song, Ali Zamat, Gabriel A. Kwong
Theranostics 2025; doi:10.7150/thno.118405; in press
Author manuscript

A novel TM4SF4-targeting therapeutic antibody candidate with antitumor activity by blocking IGF1R and CD44 signaling and downregulating PD-L1 and B7-H4
Rae-Kwon Kim, Chang-Kyu Heo, Mun Ju Choi, Yeon-jee Kahm, Min Kyu Kim, Minyong Lee, Ji Yoon Lee, Hwangseo Park, Uhee Jung, Byung-Chul Shin, Bum-Jin Kim, Sung-Chul Kim, Eun-Wie Cho, Chun Jeih Ryu, In-Gyu Kim
Theranostics 2025; doi:10.7150/thno.113347; in press
Author manuscript

Nanoparticle Retention Enables Non-invasive Detection of Metastases by Magnetic Particle Imaging in Murine Breast Cancer Models
Preethi Korangath, Hayden Carlton, Toby Sanders, Olivia C Sehl, Suqi Ke, Abdul Rahman Mohtasebzadeh, Lyndsey Werhane, Cordula Grüttner, Chen Hu, Kathleen Gabrielson, Patrick W Goodwill, Robert Ivkov
Theranostics 2025; doi:10.7150/thno.122259; accepted
Author manuscript

Long-acting management of diabetes and associated complications using an injectable thermosensitive hydrogel incorporating IgG-conjugated GLP-1RA
Lin Yu, Qinghua Wang, Hancheng Wang, Zhiyong Chen, Siyi Gu, Yaoben Wang, Yang Wang, Caiyun Gao, Jiayue Shi, Jiandong Ding
Theranostics 2025; doi:10.7150/thno.120844; in press
Author manuscript

MIF-expressing tumor cells mediate immunotherapeutic resistance in esophageal squamous cell carcinoma
Jing Song, Xiaomei Song, Yue Xie, Hong Guo, Yupeng Cun
Theranostics 2025; doi:10.7150/thno.118269; in press
Author manuscript

Emergence of a Barium Metal-Organic Framework for Mitigating Off-target Effects of Alpha Radionuclide Therapy
Long Qiu, Jie Lyu, Yuqi Guo, Shilong Shi, Xijian Chen, Junshan Geng, Qian Xiao, Jiali Liao, Yuanyou Yang, Jinsong Zhang, Ning Liu, Feize Li
Theranostics 2025; doi:10.7150/thno.121316; in press
Author manuscript

An organolutetium nanosensitizer synergizes with PARP inhibition to unleash STING-mediated immunity for low-dose radioimmunotherapy
Bingchun Zeng, Kai Ling, Qingpeng Yuan, Zeyang Chen, Guangrong Zhang, Wenyue Kang, Xuanjun Zheng, Chuanghong Liao, Youqing Mai, Zhongjie Huang, Ruibin Huang, Tiantian Zhai and Hongyan Jiang
Theranostics 2025; doi:10.7150/thno.124034; in press
Author manuscript

Programmable Molecular Microscopy: CRISPR/Cas Fluorescent Probes Revolutionizing Spatiotemporal Genomic Imaging
Xing-Yu Zhong, Yu-Xuan Yang, Yi-Fan Xiong, Gui-Chen Ye, Xi Gong, Ming-Liang Zhong, Hao-Dong He, Shao-Gang Wang, Qi-Dong Xia
Theranostics 2025; doi:10.7150/thno.125565; in press
Author manuscript

Galectin7 attenuates abdominal aortic aneurysm progression by resisting disturbed flow induced endothelial-to-mesenchymal transition
Xinzhong Li, Yanbing Wang, Yilin Zhou, Yeshen Zhang, Danni Tu, Guojun Chen, Yuan Han, Xiaomin Wei, Yanmei Chen, Senlin Huang, Yulin Liao, Wangjun Liao, Jiancheng Xiu, Yuegang Wang, Jianping Bin
Theranostics 2025; doi:10.7150/thno.117785; accepted
Author manuscript

Targeting CPS1 attenuates lung cancer metastasis by regulating EMT through an epigenetic mechanism
Yi Ding, Yuying Tian, Mengjuan Li, Yunyun Fu, Tingting Wang, Xiaoyao Du, Mingming Wang, Lele Dong, Fei Gao, Bei Liu, Yunhan Lu, Chenfei Zhang, Lin Mao, Jinhua Jiang, Lei Li, Lujian Liao, Kun Li
Theranostics 2025; doi:10.7150/thno.123679; in press
Author manuscript

ROS-responsive cellular vesicles with ferroptosis-targeting siACMSD delivery for acute kidney injury therapy
Yunjing Zhang, Qing Deng, Yangtao Xu, Wei Wu, Tian Wu, Jia Huang, Yugang Hu, Weiqiang Lin, Ximing Xuand Jicheng Wu
Theranostics 2025; doi:10.7150/thno.119667; in press
Author manuscript

Tissue-type differences in focused ultrasound and microbubble-mediated drug delivery to the brain are not fully explained by vascular density: a vessel-level analysis
Alessandro De Maio, Fa-Hsuan Lin, Bojana Stefanovic, Meaghan A. OReilly
Theranostics 2025; doi:10.7150/thno.117691; in press
Author manuscript

Nanomedicine for targeting cancer-associated fibroblasts in cancer therapy
Zi-Yi Chen, Han-Zhe Liu, Zheng-Jun Shang, Guo-Feng Luo, Xian-Zheng Zhang
Theranostics 2025; doi:10.7150/thno.120283; in press
Author manuscript

Targeted Accumulation of Reactive Acrolein via Nanoparticle-Embedded Reverse Temperature Hydrogel for Bladder Cancer Treatment
Yingying Xu, Qinglong Du, Zhongwei Zhao, Shuai Fu, Aijing Zhang, Jianguo Zheng, Chengyang Zhao, Yuxiang Meng, Hanru Liu, Zongyao Lv, Xin Qin, Huimin Geng, Nengwang Yu
Theranostics 2025; doi:10.7150/thno.119307; in press
Author manuscript

Mitochondria-specific targeting of noncanonical EGR1 ntmRNA-coordinated mitophagy receptor BNIP3 homodimerization disrupts mitochondrial metabolism and suppresses hepatocellular carcinoma growth in vitro and in vivo
Yan Li, Lei Zhou, Mengmeng Liu, Hui Li, Ying Meng, Xue Wen, Yijing Zhao, Shanshan Liu, Zi Yan, Changhao Fu, Shan Zong, Wei Li, Andrew R. Hoffman, Jiuwei Cui, Ji-Fan Hu
Theranostics 2025; doi:10.7150/thno.117745; in press
Author manuscript

Engineering and evaluation of precision-glycosylated clickable albumin nanoplatform for targeting the tumor microenvironment
Ji Yong Park, Jinyeong Choi, Jeongbin Park, Jin Sil Kim, Young Chan Ann, Hyewon Chung, Jisu Park, Seung Hyeok Seok, Hongyoon Choi, Hyung-Jun Im, Yun-Sang Lee
Theranostics 2025; doi:10.7150/thno.123973; in press
Author manuscript

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