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Review Stimuli-responsive nanomaterials for wound healing: advances and emerging directions Yijia Dong, Yaqing Zhang, Junrong Wu, Yujun Yang, Yanli Zhang, Zhenjun Zhu, Rabiya Noor, Jawad Hussain, Longquan Shao, Yi Xing Theranostics 2026; 16(12): 7029-7066. doi:10.7150/thno.133095 Full text PDF


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Research Paper Converting focused ultrasound–based boiling histotripsy into a systemic cancer vaccine using antigen-capturing microparticles Akansha Singh, Sri Vidhya Chandrasekar, Faraz Chamani, Harshini Ashar, Steve Hartson, Steve Fiering, Ashish Ranjan Theranostics 2026; 16(12): 7007-7028. doi:10.7150/thno.132091 Full text PDF


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Research Paper BMAL1 regulates tubular epithelial-derived exosomal miR-27a-3p to inhibit macrophage–myofibroblast transition and alleviate ischemia/reperfusion-induced renal fibrosis Wu Chen, Sheng Zhao, Songyuan Yang, Weimin Yu, Ting Rao, Xiangjun Zhou, Yuan Ruan, Fan Zou, Fan Cheng, Wei Li Theranostics 2026; 16(12): 6988-7006. doi:10.7150/thno.127538 Full text PDF


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Research Paper First-in-human ex-vivo validation of carbonic anhydrase IX-PET for high-risk renal cancer (CAT-VHL - PNRR-POC-2023-12377493) Alessandro Larcher, Fabrizia Gelardi, Lidija Antunovic, Annarita Savi, Michela Olivieri, Paolo Rainone, Martina Sollini, Rosa Maria Moresco, Chiara Re, Francesco Cei, Federico Belladelli, Giacomo Musso, Lucia Salerno, Francesco De Cobelli, Nazario Tenace, Maurilio Ponzoni, Antonio Cigliola, Paolo Verze, Roberto Bertini, Alberto Briganti, Francesco Montorsi, Umberto Capitanio, Andrea Salonia, Arturo Chiti Theranostics 2026; 16(12): 6980-6987. doi:10.7150/thno.122256 Full text PDF


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Review Integrating the hallmarks of cancer into autophagy: a perspective from underlying mechanisms to therapeutic strategies Huidi Liu, Wei Liu, Xiaochun Zhang, Yufeng Jiang, Heng Xu, Ningning Wang, Bo Liu, Na Lin Theranostics 2026; 16(12): 6948-6979. doi:10.7150/thno.135134 Full text PDF


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Research Paper Inhibition of SRC prevents bone metastasis of breast cancer by blocking metastatic cell motility and bone directionality Yong June Choi, Minju Kwon, Myung Jun Kim, Munkyung Choi, Phuong Thao Tran, Yujeong Lee, Wan Seob Shim, Minjae Kang, Seungseok Oh, Sung-Chul Lim, Yong-Chul Kim, Keon Wook Kang Theranostics 2026; 16(12): 6928-6947. doi:10.7150/thno.130647 Full text PDF

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Issue 10; 2026

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Founding Editor-in-Chief:
Prof. Xiaoyuan (Shawn) Chen, PhD
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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.



BMAL1 regulates tubular epithelial-derived exosomal miR-27a-3p to inhibit macrophage–myofibroblast transition and alleviate ischemia/reperfusion-induced renal fibrosis

Rationale: During ischemia‒reperfusion injury (IRI), BMAL1 has been shown to alleviate inflammation and kidney damage. However, the function of the tubular epithelium–macrophage interaction mediated by BMAL1 in IRI-induced renal fibrosis is still unclear. Methods: A mouse model of kidney-specific BMAL1 overexpression was developed to study how BMAL1 affects renal fibrosis, exosome production, and the macrophage-to-myofibroblast transition ...

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