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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
Phloretin decreases microglia-mediated synaptic engulfment to prevent chronic mild stress-induced depression-like behaviors in the mPFC
Chenchen Li, Bo Liu, Jingyi Xu, Bin Jing, Lijie Guo, Liyong Wang, Milin Wang, Haochen Zhang, Qianqian He, Xin Yu, Yan Zhang, Zhi-Qing David Xu, Yutao Yang
Theranostics 2023; 13(3): 955-972. doi:10.7150/thno.76553
[Abstract] [Full text] [PDF]


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Review
Targeted and responsive biomaterials in osteoarthritis
Jiadong Li, Hao Zhang, Yafei Han, Yan Hu, Zhen Geng, Jiacan Su
Theranostics 2023; 13(3): 931-954. doi:10.7150/thno.78639
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Research Paper
Photobiomodulation attenuates oligodendrocyte dysfunction and prevents adverse neurological consequences in a rat model of early life adversity
Zhihai Huang, Yulan Zhang, Xiaohui Ma, Yu Feng, Xuemei Zong, J. Dedrick Jordan, Quanguang Zhang
Theranostics 2023; 13(3): 913-930. doi:10.7150/thno.78777
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Research Paper
TCRαβ+NK1.1-CD4-CD8- double-negative T cells inhibit central and peripheral inflammation and ameliorate ischemic stroke in mice
Dan Tian, Yuhualei Pan, Yushang Zhao, Huan Wang, Yue Tian, Lu Yang, Wen Shi, Chengjie Zhang, Yanbing Zhu, Yongbo Zhang, Songlin Wang, Dong Zhang
Theranostics 2023; 13(3): 896-909. doi:10.7150/thno.80307
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Research Paper
NQO1 regulates cell cycle progression at the G2/M phase
Eun-Taex Oh, Ha Gyeong Kim, Chul Hoon Kim, Jeonghun Lee, Chulhee Kim, Jae-Seon Lee, Yunmi Cho, Heon Joo Park
Theranostics 2023; 13(3): 873-895. doi:10.7150/thno.77444
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Research Paper
Kruppel-like factor 2 contributes to blood-spinal cord barrier integrity and functional recovery from spinal cord injury by augmenting autophagic flux
Zili He, Jiqing Du, Yu Zhang, Yitie Xu, Qian Huang, Qingwei Zhou, Min Wu, Yao Li, Xie Zhang, Hongyu Zhang, Yuepiao Cai, Keyong Ye, Xiangyang Wang, Yingze Zhang, Qi Han, Jian Xiao
Theranostics 2023; 13(2): 849-866. doi:10.7150/thno.74324
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
ALKBH5 activates FAK signaling through m6A demethylation in ITGB1 mRNA and enhances tumor-associated lymphangiogenesis and lymph node metastasis in ovarian cancer
Rui Sun, Lin Yuan, Yi Jiang, Yicong Wan, Xiaolling Ma, Jing Yang, Guodong Sun, Shulin Zhou, Hui Wang, Jiangnan Qiu, Lin Zhang, Wenjun Cheng
Theranostics 2023; 13(2): 833-848. doi:10.7150/thno.77441
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
3,4-Dimethoxychalcone, a caloric restriction mimetic, enhances TFEB-mediated autophagy and alleviates pyroptosis and necroptosis after spinal cord injury
Haojie Zhang, Wenfei Ni, Gaoxiang Yu, Yibo Geng, Junsheng Lou, Jianjun Qi, Yituo Chen, Feida Li, Hantao Ye, Haiwei Ma, Hui Xu, Luying Zhao, Yuepiao Cai, Xiangyang Wang, Huazi Xu, Jian Xiao, Kailiang Zhou
Theranostics 2023; 13(2): 810-832. doi:10.7150/thno.78370
[Abstract] [Full text] [PDF] [PubMed] [PMC]

More ...

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile


CFP: Special issue on mRNA-based vaccine and therapy. Guest Editors: Guocan Yu (Tsinghua University, China), Qiaobing Xu (Tufts University, USA), Wei Tao (Harvard Medical School, USA)


Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Gold Nanoparticles Conjugated with Dendrigraft Poly-L-lysine and Folate-Targeted Poly(ethylene glycol) for siRNA Delivery to Prostate cancer
Georges Minassian, Esther Ghanem, Roland El Hage, Kamil Rahme
Nanotheranostics 2023; 7(2): 152-166. doi:10.7150/ntno.79050
[Abstract] [Full text] [PDF]


Research Paper
Longitudinal NMR Based Serum Metabolomics to Track the Potential Serum Biomarkers of Septic Shock
Swarnima Pandey, Afzal Azim, Neeraj Sinha
Nanotheranostics 2023; 7(2): 142-151. doi:10.7150/ntno.79394
[Abstract] [Full text] [PDF]



Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr. Magali Cucchiarini.


Congratulations to Dr. Chen for being elected as AIMBE fellow.


Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.


Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).


NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.