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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
SGLT2 inhibitor dapagliflozin reduces endothelial dysfunction and microvascular damage during cardiac ischemia/reperfusion injury through normalizing the XO-SERCA2-CaMKII-coffilin pathways
Li Ma, Rongjun Zou, Wanting Shi, Na Zhou, Shaoxian Chen, Hao Zhou, Xinxin Chen, Yueheng Wu
Theranostics 2022; 12(11): 5034-5050. doi:10.7150/thno.75121
[Abstract] [Full text] [PDF]


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Review
Therapeutic angiogenesis-based strategy for peripheral artery disease
Jingxuan Han, Lailiu Luo, Olivia Marcelina, Vivi Kasim, Shourong Wu
Theranostics 2022; 12(11): 5015-5033. doi:10.7150/thno.74785
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Review
Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development
Lingchi Kong, Xin Gao, Yun Qian, Wei Sun, Zhengwei You, Cunyi Fan
Theranostics 2022; 12(11): 4993-5014. doi:10.7150/thno.74571
[Abstract] [Full text] [PDF]


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Research Paper
Single-cell profiling of microenvironment components by spatial localization in pancreatic ductal adenocarcinoma
Song Han, Dongtao Fu, Gerik W Tushoski, Lingsong Meng, Kelly M. Herremans, Andrea N. Riner, Thomas J. Geoge, Zhiguang Huo, Steven J. Hughes
Theranostics 2022; 12(11): 4980-4992. doi:10.7150/thno.73222
[Abstract] [Full text] [PDF]


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Research Paper
Docetaxel remodels prostate cancer immune microenvironment and enhances checkpoint inhibitor-based immunotherapy
Zehua Ma, Weiwei Zhang, Baijun Dong, Zhixiang Xin, Yiyi Ji, Ruopeng Su, Kai Shen, Jiahua Pan, Qi Wang, Wei Xue
Theranostics 2022; 12(11): 4965-4979. doi:10.7150/thno.73152
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Research Paper
A theranostic 3D ultrasound imaging system for high resolution image-guided therapy
Hanna Bendjador, Josquin Foiret, Robert Wodnicki, Douglas N Stephens, Zoe Krut, Eun-Yeong Park, Zulma Gazit, Dan Gazit, Gadi Pelled, Katherine W Ferrara
Theranostics 2022; 12(11): 4949-4964. doi:10.7150/thno.71221
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Review
Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents
Qingjuan Chen, Binhui Yang, Xiaochen Liu, Xu D. Zhang, Lirong Zhang, Tao Liu
Theranostics 2022; 12(11): 4935-4948. doi:10.7150/thno.73223
[Abstract] [Full text] [PDF]


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Research Paper
KDM4 inhibitor SD49-7 attenuates leukemia stem cell via KDM4A/MDM2/p21CIP1 axis
Yinghui Li, Chaoqun Wang, Huier Gao, Jiali Gu, Yiran Zhang, Yingyi Zhang, Min Xie, Xuelian Cheng, Ming Yang, Wenshan Zhang, Yafang Li, Mei He, Hui Xu, Hexiao Zhang, Qing Ji, Tianhua Ma, Sheng Ding, Yu Zhao, Yingdai Gao
Theranostics 2022; 12(11): 4922-4934. doi:10.7150/thno.71460
[Abstract] [Full text] [PDF]

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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile


CFP: Virtual Special Issue - Patient-derived cancer models: from molecular mechanisms to clinical translation. Guest Editors: Christian Pilarsky, PhD (Friedrich-Alexander University of Erlangen), Yana Zavros, PhD (University of Arizona Cancer Center), Qingfeng Chen, PhD (National University of Singapore), and Xin Hong, PhD (Southern University of Science and Technology)


Special issue on the thematic conference Nanomedicine meets the tumor microenvironment - NanoTME 2021. Guest Editors: Jai Prakash (University of Twente, The Netherlands) and Yuval Shaked (Technicon, Israel)


Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Ultrasound-triggered oxygen-loaded nanodroplets enhance and monitor cerebral damage from sonodynamic therapy
Harriet Lea-Banks, Sheng-Kai Wu, Hannah Lee, Kullervo Hynynen
Nanotheranostics 2022; 6(4): 376-387. doi:10.7150/ntno.71946
[Abstract] [Full text] [PDF]


Review
Emerging Role of Edible Exosomes-Like Nanoparticles (ELNs) as Hepatoprotective Agents
P. Debishree Subudhi, Chhagan Bihari, Shiv Kumar Sarin, Sukriti Baweja
Nanotheranostics 2022; 6(4): 365-375. doi:10.7150/ntno.70999
[Abstract] [Full text] [PDF]



Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr. Magali Cucchiarini.


Congratulations to Dr. Chen for being elected as AIMBE fellow.


Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.


Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).


NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.