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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells
Lena Hölzen, Jan Mitschke, Claudia Schönichen, Maria Elena Hess, Sophia Ehrenfeld, Melanie Boerries, Cornelius Miething, Tilman Brummer, Thomas Reinheckel
Theranostics 2022; 12(9): 4348-4373. doi:10.7150/thno.68299
[Abstract] [Full text] [PDF]


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Research Paper
PTRF/Cavin-1 enhances chemo-resistance and promotes temozolomide efflux through extracellular vesicles in glioblastoma
Eryan Yang, Lin Wang, Weili Jin, Xing Liu, Qixue Wang, Ye Wu, Yanli Tan, Yunfei Wang, Xiaoteng Cui, Jixing Zhao, Fei Tong, Biao Hong, Menglin Xiao, Xiaomin Liu, Chuan Fang, Chunsheng Kang
Theranostics 2022; 12(9): 4330-4347. doi:10.7150/thno.71763
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Review
Pyroptosis in inflammatory diseases and cancer
Zhiping Rao, Yutong Zhu, Peng Yang, Zhuang Chen, Yuqiong Xia, Chaoqiang Qiao, Weijing Liu, Hongzhang Deng, Jianxiong Li, Pengbo Ning, Zhongliang Wang
Theranostics 2022; 12(9): 4310-4329. doi:10.7150/thno.71086
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Research Paper
Grafted human ESC-derived astroglia repair spinal cord injury via activation of host anti-inflammatory microglia in the lesion area
Jian Wang, Peng Jiang, Wenbin Deng, Yuhui Sun, Yaobo Liu
Theranostics 2022; 12(9): 4288-4309. doi:10.7150/thno.70929
[Abstract] [Full text] [PDF]


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Review
Circular RNAs modulate Hippo-YAP signaling: functional mechanisms in cancer
Javeria Qadir, Feiya Li, Burton B. Yang
Theranostics 2022; 12(9): 4269-4287. doi:10.7150/thno.71708
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Research Paper
pH-responsive hybrid platelet membrane-coated nanobomb with deep tumor penetration ability and enhanced cancer thermal/chemodynamic therapy
Huang Yang, Yuan Ding, Zongrui Tong, Xiaohui Qian, Hao Xu, Fenghao Lin, Guoping Sheng, Liangjie Hong, Weilin Wang, Zhengwei Mao
Theranostics 2022; 12(9): 4250-4268. doi:10.7150/thno.68996
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Research Paper
Extracellular vesicle-derived miR-144 as a novel mechanism for chronic intermittent hypoxia-induced endothelial dysfunction
Huina Zhang, Lu Peng, Yifan Wang, Wen Zhao, Wayne Bond Lau, Yajing Wang, Yu Li, Yunhui Du, Linyi Li, Yu Huang, Shaoping Nie, Yanwen Qin, Xinliang Ma, Yongxiang Wei
Theranostics 2022; 12(9): 4237-4249. doi:10.7150/thno.69035
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Research Paper
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling
Peng Peng, Hongtao Zhu, Dan Liu, Zirong Chen, Xiaolin Zhang, Zhongyin Guo, Minhai Dong, Lijun Wan, Po Zhang, Guohao Liu, Suojun Zhang, Fangyong Dong, Feng Hu, Fangling Cheng, Shijun Huang, Dongsheng Guo, Bin Zhang, Xingjiang Yu, Feng Wan
Theranostics 2022; 12(9): 4221-4236. doi:10.7150/thno.69605
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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

new Latest Impact Factor 11.556.


CFP: Virtual Special Issue - Patient-derived cancer models: from molecular mechanisms to clinical translation. Guest Editors: Christian Pilarsky, PhD (Friedrich-Alexander University of Erlangen), Yana Zavros, PhD (University of Arizona Cancer Center), Qingfeng Chen, PhD (National University of Singapore), and Xin Hong, PhD (Southern University of Science and Technology)


Special issue on the thematic conference Nanomedicine meets the tumor microenvironment - NanoTME 2021. Guest Editors: Jai Prakash (University of Twente, The Netherlands) and Yuval Shaked (Technicon, Israel)


Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Surface enhanced deep Raman detection of cancer tumour through 71 mm of heterogeneous tissue
Priyanka Dey, Alexandra Vaideanu, Sara Mosca, Marzieh Salimi, Benjamin Gardner, Francesca Palombo, Ijeoma Uchegbu, Jeremy Baumberg, Andreas Schatzlein, Pavel Matousek, Nick Stone
Nanotheranostics 2022; 6(3): 337-349. doi:10.7150/ntno.71510
[Abstract] [Full text] [PDF]


Research Paper
EK-16A liposomes enhance HIV replication in ACH2 or J-Lat 10.6 cell engrafted NSG mice
Panpan Lu, Jinlong Yang, Xinyi Yang, Zhiming Liang, Jing Wang, Yanan Wang, Lin Zhao, Hanyu Pan, Xiaoting Shen, Yuqi Zhu, Jingna Xun, Hongzhou Lu, Huanzhang Zhu
Nanotheranostics 2022; 6(3): 325-336. doi:10.7150/ntno.69259
[Abstract] [Full text] [PDF]



Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr. Magali Cucchiarini.


Congratulations to Dr. Chen for being elected as AIMBE fellow.


Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.


Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).


NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.