Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Research Paper
Glutamine is essential for overcoming the immunosuppressive microenvironment in malignant salivary gland tumors
Shuting Cao, Yu-Wen Hung, Yi-Chang Wang, Yiyin Chung, Yue Qi, Ching Ouyang, Xiancai Zhong, Weidong Hu, Alaysia Coblentz, Ellie Maghami, Zuoming Sun, H. Helen Lin, David K. Ann
Theranostics 2022; 12(13): 6038-6056. doi:10.7150/thno.73896
[Abstract] [Full text] [PDF]

Research Paper
Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair
Dake Hao, Lu Lu, Hengyue Song, Yixin Duan, Jianing Chen, Randy Carney, Jian Jian Li, Ping Zhou, Jan Nolta, Kit S. Lam, J. Kent Leach, Diana L Farmer, Alyssa Panitch, Aijun Wang
Theranostics 2022; 12(13): 6021-6037. doi:10.7150/thno.70448
[Abstract] [Full text] [PDF]

Review
Emerging nanozyme-based multimodal synergistic therapies in combating bacterial infections
Yanmei Zhang, Xin Hu, Jing Shang, Wenhui Shao, Liming Jin, Chunshan Quan, Jun Li
Theranostics 2022; 12(13): 5995-6020. doi:10.7150/thno.73681
[Abstract] [Full text] [PDF]

Research Paper
Reduced splenic uptake on ⁶⁸Ga-Pentixafor-PET/CT imaging in multiple myeloma - a potential imaging biomarker for disease prognosis
Sabrina Kraus, Philipp Klassen, Malte Kircher, Alexander Dierks, Stefan Habringer, Alexander Gäble, Klaus Martin Kortüm, Niels Weinhold, Valëza Ademaj-Kospiri, Rudolf A Werner, Andreas Schirbel, Andreas K Buck, Peter Herhaus, Hans-Jürgen Wester, Andreas Rosenwald, Wolfgang A Weber, Hermann Einsele, Ulrich Keller, Leo Rasche, Constantin Lapa
Theranostics 2022; 12(13): 5986-5994. doi:10.7150/thno.75847
[Abstract] [Full text] [PDF]

Research Paper
3p-C-NETA: A versatile and effective chelator for development of Al¹⁸F-labeled and therapeutic radiopharmaceuticals
Stephen Ahenkorah, Erika Murce, Christopher Cawthorne, Jessica Pougoue Ketchemen, Christophe M. Deroose, Thomas Cardinaels, Yann Seimbille, Humphrey Fonge, Willy Gsell, Guy Bormans, Maarten Ooms, Frederik Cleeren
Theranostics 2022; 12(13): 5971-5985. doi:10.7150/thno.75336
[Abstract] [Full text] [PDF]

Research Paper
CRISPR/Cas9-based genome-wide screening for deubiquitinase subfamily identifies USP1 regulating MAST1-driven cisplatin-resistance in cancer cells
Apoorvi Tyagi, Kamini Kaushal, Arun Pandian Chandrasekaran, Neha Sarodaya, Soumyadip Das, Chang-Hwan Park, Seok-Ho Hong, Kye-Seong Kim, Suresh Ramakrishna
Theranostics 2022; 12(13): 5949-5970. doi:10.7150/thno.72826
[Abstract] [Full text] [PDF]

Research Paper
Machine learning-based identification of tumor-infiltrating immune cell-associated lncRNAs for improving outcomes and immunotherapy responses in patients with low-grade glioma
Nan Zhang, Hao Zhang, Wantao Wu, Ran Zhou, Shuyu Li, Zeyu Wang, Ziyu Dai, Liyang Zhang, Fangkun Liu, Zaoqu Liu, Jian Zhang, Peng Luo, Zhixiong Liu, Quan Cheng
Theranostics 2022; 12(13): 5931-5948. doi:10.7150/thno.74281
[Abstract] [Full text] [PDF]

Research Paper
A CRISPR-Cas12a integrated SERS nanoplatform with chimeric DNA/RNA hairpin guide for ultrasensitive nucleic acid detection
Bohan Yin, Qin Zhang, Xinyue Xia, Chuanqi Li, Willis Kwun Hei Ho, Jiaxiang Yan, Yingying Huang, Honglian Wu, Pui Wang, Changqing Yi, Jianhua Hao, Jianfang Wang, Honglin Chen, Siu Hong Dexter Wong, Mo Yang
Theranostics 2022; 12(13): 5914-5930. doi:10.7150/thno.75816
[Abstract] [Full text] [PDF]

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