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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
HDAC6 inhibition reverses long-term doxorubicin-induced cognitive dysfunction by restoring microglia homeostasis and synaptic integrity
Blake R McAlpin, Rajasekaran Mahalingam, Anand K Singh, Shruti Dharmaraj, Taylor T Chrisikos, Nabila Boukelmoune, Annemieke Kavelaars, Cobi J Heijnen
Theranostics 2022; 12(2): 603-619. doi:10.7150/thno.67410
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Review
Tailoring noble metal nanoparticle designs to enable sensitive lateral flow immunoassay
Xirui Chen, Lu Ding, Xiaolin Huang, Yonghua Xiong
Theranostics 2022; 12(2): 574-602. doi:10.7150/thno.67184
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Research Paper
Non-invasive longitudinal imaging of VEGF-induced microvascular alterations in skin wounds
Yu-Hang Liu, Lorenz M. Brunner, Johannes Rebling, Maya Ben-Yehuda Greenwald, Sabine Werner, Michael Detmar, Daniel Razansky
Theranostics 2022; 12(2): 558-573. doi:10.7150/thno.65287
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Review
Light on osteoarthritic joint: from bench to bed
Yingying Zhou, Junguo Ni, Chunyi Wen, Puxiang Lai
Theranostics 2022; 12(2): 542-557. doi:10.7150/thno.64340
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Research Paper
Modulation of H4K16Ac levels reduces pro-fibrotic gene expression and mitigates lung fibrosis in aged mice
Xiangyu Zhang, Hui Liu, Jennifer Q Zhou, Stefanie Krick, Jarrod W Barnes, Victor J Thannickal, Yan Y Sanders
Theranostics 2022; 12(2): 530-541. doi:10.7150/thno.62760
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Research Paper
Monocytes promote acute neuroinflammation and become pathological microglia in neonatal hypoxic-ischemic brain injury
Hong-Ru Chen, Ching-Wen Chen, Yi-Min Kuo, Brandon Chen, Irena S. Kuan, Henry Huang, Jolly Lee, Neil Anthony, Chia-Yi Kuan, Yu-Yo Sun
Theranostics 2022; 12(2): 512-529. doi:10.7150/thno.64033
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Review
Glucose biosensors in clinical practice: principles, limits and perspectives of currently used devices
Salvatore Andrea Pullano, Marta Greco, Maria Giovanna Bianco, Daniela Foti, Antonio Brunetti, Antonino S. Fiorillo
Theranostics 2022; 12(2): 493-511. doi:10.7150/thno.64035
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Research Paper
A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy
Audrey Champagne, Pallavi Jain, Lauriane Vélot, Julie Riopel, Véronique Lefebvre, Bertrand Neveu, Frédéric Pouliot
Theranostics 2022; 12(2): 474-492. doi:10.7150/thno.63744
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Research Paper
Comprehensive omics analyses profile genesets related with tumor heterogeneity of multifocal glioblastomas and reveal LIF/CCL2 as biomarkers for mesenchymal subtype
Sheng-Qing Lv, Zhen Fu, Lin Yang, Qing-Rui Li, Jiang Zhu, Qu-Jing Gai, Min Mao, Jiang He, Yan Qin, Xiao-Xue Yao, Xi Lan, Yan-Xia Wang, Hui-Min Lu, Yan Xiang, Zuo-Xin Zhang, Guo-Hao Huang, Wei Yang, Ping Kang, Zhijian Sun, Yu Shi, Xiao-Hong Yao, Xiu-Wu Bian, Yan Wang
Theranostics 2022; 12(1): 459-473. doi:10.7150/thno.65739
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Review
Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy
Bin Ji, Minjie Wei, Bin Yang
Theranostics 2022; 12(1): 434-458. doi:10.7150/thno.67300
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Research Paper
Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics
Xuejun Wen, Pengfei Xu, Mengqi Shi, Jia Liu, Xinying Zeng, Yiren Zhang, Changrong Shi, Jingchao Li, Zhide Guo, Xianzhong Zhang, Pek-Lan Khong, Xiaoyuan Chen
Theranostics 2022; 12(1): 422-433. doi:10.7150/thno.68182
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Erratum
Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis: Erratum
Haoran Liu, Xiaoqi Yang, Kun Tang, Tao Ye, Chen Duan, Peng Lv, Libin Yan, Xiaoliang Wu, Zhiqiang Chen, Jianhe Liu, Yaoliang Deng, Guohua Zeng, Jinchun Xing, Zhangqun Ye, Hua Xu
Theranostics 2022; 12(1): 421. doi:10.7150/thno.68830
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Erratum
Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma: Erratum
Libin Yan, Beichen Ding, Haoran Liu, Yangjun Zhang, Jin Zeng, Junhui Hu, Weimin Yao, Gan Yu, Ruihua An, Zhiqiang Chen, Zhangqun Ye, Jinchun Xing, Kefeng Xiao, Lily Wu, Hua Xu
Theranostics 2022; 12(1): 419-420. doi:10.7150/thno.68810
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Erratum
NLRP3 inflammasome via IL-1β regulates PCSK9 secretion: Erratum
Zufeng Ding, Xianwei Wang, Shijie Liu, Sichang Zhou, Rajshekhar A Kore, Shengyu Mu, Xiaoyan Deng, Yubo Fan, Jawahar L Mehta
Theranostics 2022; 12(1): 418. doi:10.7150/thno.68759
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Research Paper
Simultaneous enhancement of T1 and T2 magnetic resonance imaging of liver tumor at respective low and high magnetic fields
Huan Li, Zijuan Hai, Liwei Zou, Lele Zhang, Lulu Wang, Longsheng Wang, Gaolin Liang
Theranostics 2022; 12(1): 410-417. doi:10.7150/thno.67155
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Research Paper
A hypoxia-responsive supramolecular formulation for imaging-guided photothermal therapy
Tian-Xing Zhang, Xiaoxue Hou, Yong Kong, Fan Yang, Yu-Xin Yue, Muhammad Raza Shah, Hua-Bin Li, Fan Huang, Jianfeng Liu, Dong-Sheng Guo
Theranostics 2022; 12(1): 396-409. doi:10.7150/thno.67036
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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

new Latest Impact Factor 11.556.


Special issue on the thematic conference Nanomedicine meets the tumor microenvironment - NanoTME 2021. Guest Editors: Jai Prakash (University of Twente, The Netherlands) and Yuval Shaked (Technicon, Israel)

Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Lipid nitroalkene nanoparticles for the focal treatment of ischemia reperfusion
Gary Z Yu, Thiruganesh Ramasamy, Marco Fazzari, Xucai Chen, Bruce Freeman, John J Pacella
Nanotheranostics 2022; 6(2): 215-229. doi:10.7150/ntno.62351
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Research Paper
Graphene Quantum Dots prepared by Electron Beam Irradiation for Safe Fluorescence Imaging of Tumor
Honghong Cao, Wei Qi, Xudong Gao, Qiang Wu, Longlong Tian, Wangsuo Wu
Nanotheranostics 2022; 6(2): 205-214. doi:10.7150/ntno.67070
[Abstract] [Full text] [PDF]


Research Paper
Pharmacokinetic/Pharmacodynamic Determinations of Iron-tannic Molecular Nanoparticles with its Implication in MR Imaging and Enhancement of Liver Clearance
Thipjutha Phatruengdet, Piyachat Khuemjun, Jannarong Intakhad, Saowalak Krunchanuchat, Arpamas Chariyakornkul, Rawiwan Wongpoomchai, Chalermchai Pilapong
Nanotheranostics 2022; 6(2): 195-204. doi:10.7150/ntno.63310
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Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr. Magali Cucchiarini.
Special Issue: Extracellular vesicles in pathogenesis, diagnosis, or therapeutics of human diseases. Guest Editor: Ming-Lin Liu, Perelman School of Medicine, University of Pennsylvania.
Special Issue: Noble-metal Nanostructures for Theranostics. Guest Editors: Xiaohu Xia, University of Central Florida and Hui Wei, Nanjing University
Special Issue Targeting the Cancer Stem Cells. Guest Editor: Fei Chen, PhD, Professor, Wayne State University
Special Issue Progress in Gene Editing Nanotheranostics. Guest Editors: Gang Han (University of Massachusetts Medical School), Wen Xue (University of Massachusetts Medical School), Qiaobing Xu (Tufts University)
Special Issue Progress in Supramolecular Nanotheranostics. Guest Editors: Xiaoyuan (Shawn) Chen (NIBIB/NIH); Gang Zheng (University of Toronto); Jianjun Cheng (University of Illinois Urbana-Champaign); Yi-Yan Yang (Institute of Bioengineering and Nanotechnology, Singapore)

Congratulations to Dr. Chen for being elected as AIMBE fellow: https://aimbe.org/college-of-fellows/cof-2103/

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.


NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).