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Volume 15 (8); 2025

Research Papers

CRISPR screening reveals ZNF217 as a vulnerability in high-risk B-cell acute lymphoblastic leukemia
Xi Qin, Keren Zhou, Lei Dong, Lu Yang, Wei Li, Zhenhua Chen, Chao Shen, Li Han, Yangchan Li, Anthony K.N. Chan, Sheela Pangeni Pokharel, Ying Qing, Meiling Chen, Kitty Wang, Keith Leung, Lillian Sau, Chun-Wei Chen, Xiaolan Deng, Rui Su, Jianjun Chen
Theranostics 2025; 15(8): 3234-3256. doi:10.7150/thno.100295
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Oxytocin modulates inhibitory balance in the prelimbic cortex to support social memory consolidation during REM sleep
Yan-chao Liu, Yu-chen Deng, Zi-tao Zhu, Bo Rao, Hong-lei Shang, Li-ke Wang, Tao Li, Ya-rong Wang, Jian-Zhi Wang, Qing-ping Zhang, Yang Gao, Hai-bo Xu
Theranostics 2025; 15(8): 3257-3274. doi:10.7150/thno.109104
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SPEAR: CRISPR-mediated ultrasensitive, specific and rapid one-pot detection strategy for cancer-related SNPs
Linlin Bai, Yanan Pang, Ting Wang, Shengzhou Wang, Kaiming Guo, Tian Xuan, Ziqin Zhang, Dianwei Liu, Feng Qian, Yan Zheng, Gang Jin, Rui Wang
Theranostics 2025; 15(8): 3275-3288. doi:10.7150/thno.107488
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PBRM1 deficiency enhances PD1 immunotherapeutic sensitivity via chromosomal accessibility in colorectal cancer
Rui Li, Jie He, Chaoqun Liu, Zesheng Jiang, Jiasheng Qin, Kun Liang, Zhuocheng Ji, Liang Zhao
Theranostics 2025; 15(8): 3316-3331. doi:10.7150/thno.100793
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Sex- and age-specific sensitivities of the endocannabinoid system in Alzheimer's disease revealed by PET imaging with [¹⁸F]FMPEP-d₂ and [¹⁸F]MAGL-2102
Anna Pees, Christopher Daniel Morrone, Junchao Tong, Jian Rong, Tuo Shao, Darcy Wear, Steven H. Liang, Wai Haung Yu, Neil Vasdev
Theranostics 2025; 15(8): 3368-3385. doi:10.7150/thno.106592
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Reviews

Artificial intelligence-enhanced retinal imaging as a biomarker for systemic diseases
Jinyuan Wang, Ya Xing Wang, Dian Zeng, Zhuoting Zhu, Dawei Li, Yuchen Liu, Bin Sheng, Andrzej Grzybowski, Tien Yin Wong
Theranostics 2025; 15(8): 3223-3233. doi:10.7150/thno.100786
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Engineered Probiotic-Based Biomaterials for Inflammatory Bowel Disease Treatment
Guangze Sang, Bingkai Wang, Yujie Xie, Yu Chen, Feng Yang
Theranostics 2025; 15(8): 3289-3315. doi:10.7150/thno.103983
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Antigen-presenting fibroblasts: emerging players in immune modulation and therapeutic targets
Xiaoyun Chen, Fangqi Chen, Sujie Jia, Qianjin Lu, Ming Zhao
Theranostics 2025; 15(8): 3332-3344. doi:10.7150/thno.104900
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Supercharging CAR-T cells through transcriptional and epigenetic armoring
Diyuan Qin, Yanna Lei, Pei Shu, Yugu Zhang, Yuin-Han Loh, Yongsheng Wang, Qijing Li
Theranostics 2025; 15(8): 3345-3367. doi:10.7150/thno.107908
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