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Volume 14 (12); 2024
Research Papers
Impact of TP53 loss-of-function alterations on the response to PSMA radioligand therapy in metastatic castration-resistant prostate cancer patients Peter H.J. Slootbeek, María Victoria Luna-Velez, Bastiaan M. Privé, Maarten J. van der Doelen, Iris S.H. Kloots, Samhita Pamidimarri Naga, Hilde E. Onstenk, James Nagarajah, Harm Westdorp, Inge M. van Oort, Leonie I. Kroeze, Jack. A. Schalken, Haiko J. Bloemendal, Niven Mehra
Theranostics 2024; 14(12): 4555-4569. doi:10.7150/thno.96322
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A novel assessment of whole-mount Gleason grading in prostate cancer to identify candidates for radical prostatectomy: a machine learning-based multiomics study Jing Ning, Clemens P. Spielvogel, David Haberl, Karolina Trachtova, Stefan Stoiber, Sazan Rasul, Vojtech Bystry, Gabriel Wasinger, Pascal Baltzer, Elisabeth Gurnhofer, Gerald Timelthaler, Michaela Schlederer, Laszlo Papp, Helga Schachner, Thomas Helbich, Markus Hartenbach, Bernhard Grubmüller, Shahrokh F Shariat, Marcus Hacker, Alexander Haug, Lukas Kenner
Theranostics 2024; 14(12): 4570-4581. doi:10.7150/thno.96921
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In-depth cross-validation of human and mouse CD4-specific minibodies for noninvasive PET imaging of CD4+ cells and response prediction to cancer immunotherapy Stefania Pezzana, Simone Blaess, Jule Kortendieck, Nicole Hemmer, Bredi Tako, Claudia Pietura, Lara Ruoff, Simon Riel, Martin Schaller, Irene Gonzalez-Menendez, Leticia Quintanilla-Martinez, Alessandro Mascioni, Argin Aivazian, Ian Wilson, Andreas Maurer, Bernd J. Pichler, Manfred Kneilling, Dominik Sonanini
Theranostics 2024; 14(12): 4582-4597. doi:10.7150/thno.95173
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Reconstituting gut microbiota-colonocyte interactions reverses diet-induced cognitive deficits: The beneficial of eucommiae cortex polysaccharides Mengli Wang, Penghao Sun, Xuejun Chai, Yong-Xin Liu, Luqi Li, Wei Zheng, Shulin Chen, Xiaoyan Zhu, Shanting Zhao
Theranostics 2024; 14(12): 4622-4642. doi:10.7150/thno.99468
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The biphasic role of Hspb1 on ferroptotic cell death in Parkinson's disease Jieyi Meng, Jinyu Fang, Yutong Bao, Huizhu Chen, Xiaodan Hu, Ziyuan Wang, Man Li, Quancheng Cheng, Yaqiong Dong, Xiaoda Yang, Yushu Zou, Dongyu Zhao, Jiping Tang, Weiguang Zhang, Chunhua Chen
Theranostics 2024; 14(12): 4643-4666. doi:10.7150/thno.98457
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A relay-type innate immunity activation strategy involving water-soluble NIR-II AIEgen for boosted tumor photo-immunotherapy Shanshan Liu, Yan Sun, Dingyuan Yan, Wen Song, Jiajia Fu, Shanyong Wang, Tianhao Yang, Jun Zhu, Dongxia Zhu, Dong Wang, Feifan Zhou, Ben Zhong Tang
Theranostics 2024; 14(12): 4667-4682. doi:10.7150/thno.95724
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Development and preclinical characterization of a novel radiotheranostic EphA2-targeting bicyclic peptide Mohamed El Fakiri, Anusha R. Regupathy, Lisa Uhlmann, Nawal Ayada, Nicolas M. Geis, Lisa-Charlotte Domogalla, Johanna Lahdenranta, Ben Blakeman, Francesca Wood, Philipp T. Meyer, Philip Huxley, Matthias Eder, Gemma E. Mudd, Ann-Christin Eder
Theranostics 2024; 14(12): 4701-4712. doi:10.7150/thno.96641
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Activation of Toll-like receptor 2 promotes mesenchymal stem/stromal cell-mediated immunoregulation and angiostasis through AKR1C1 Jung Hwa Ko, Hyun Ju Lee, Chang Ho Yoon, Yoo Rim Choi, Jin Suk Ryu, Joo Youn Oh
Theranostics 2024; 14(12): 4713-4729. doi:10.7150/thno.100327
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Apoptotic vesicle-mediated senolytics requires mechanical loading Zhulin Xue, Yexiang Jiang, Bowen Meng, Lu Lu, Meng Hao, Yi Zhang, Songtao Shi, Zili Li, Xueli Mao
Theranostics 2024; 14(12): 4730-4746. doi:10.7150/thno.98763
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Brain-targeted intranasal delivery of protein-based gene therapy for treatment of ischemic stroke Jee-Yeon Ryu, Christian Cerecedo-Lopez, Hongkuan Yang, Ilhwan Ryu, Rose Du
Theranostics 2024; 14(12): 4773-4786. doi:10.7150/thno.98088
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Single-cell RNA sequencing highlights the immunosuppression of IDO1+ macrophages in the malignant transformation of oral leukoplakia Yu Zhang, Jie Zhang, Simin Zhao, Yan Xu, Yingying Huang, Shaopeng Liu, Peng Su, Caijiao Wang, Yahui Li, Hao Li, Pishan Yang, Chengzhe Yang
Theranostics 2024; 14(12): 4787-4805. doi:10.7150/thno.99112
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DAB2+ macrophages support FAP+ fibroblasts in shaping tumor barrier and inducing poor clinical outcomes in liver cancer Fei Long, Wei Zhong, Faming Zhao, Yaqi Xu, Xin Hu, Gaihua Jia, Lanxiang Huang, Kezhen Yi, Na Wang, Huaqi Si, Jun Wang, Bicheng Wang, Yuan Rong, Yufeng Yuan, Chunhui Yuan, Fubing Wang
Theranostics 2024; 14(12): 4822-4843. doi:10.7150/thno.99046
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Single cell RNA-sequencing delineates CD8+ tissue resident memory T cells maintaining rejection in liver transplantation Xinqiang Li, Shipeng Li, Yan Wang, Xin Zhou, Feng Wang, Imran Muhammad, Yurong Luo, Yandong Sun, Dan Liu, Bin Wu, Dahong Teng, Jinshan Wang, Kai Zhao, Qi Ling, Jinzhen Cai
Theranostics 2024; 14(12): 4844-4860. doi:10.7150/thno.96928
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Metal-organic cage as a theranostic nanoplatform for magnetic resonance imaging guided chemodynamic therapy Peilin Yin, Demei Sun, Yucen Deng, Xinyuan Zhu, Youfu Wang, Jinghui Yang, Xuesong Feng
Theranostics 2024; 14(12): 4861-4873. doi:10.7150/thno.97264
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Engaging natural regulatory myeloid cells to restrict T-cell hyperactivation-induced liver inflammation via extracellular vesicle-mediated purine metabolism regulation Fan Yang, Ruoting Men, Linling Lv, Leyu Zhou, Qiaoyu Deng, Xianglin Wang, Jingping Liu, Li Yang
Theranostics 2024; 14(12): 4874-4893. doi:10.7150/thno.97427
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Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system Yueheng Wu, Shaoxian Chen, Guiping Huang, Lu Zhang, Liying Zhong, Yi Feng, Pengju Wen, Juli Liu
Theranostics 2024; 14(12): 4894-4915. doi:10.7150/thno.92060
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Reviews
Exosome-like nanoparticles derived from fruits, vegetables, and herbs: innovative strategies of therapeutic and drug delivery Bo Zhao, Hangjuan Lin, Xinchi Jiang, Wanshu Li, Yuli Gao, Minghui Li, Yanan Yu, Ninggang Chen, Jianqing Gao
Theranostics 2024; 14(12): 4598-4621. doi:10.7150/thno.97096
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The role of m6A-associated membraneless organelles in the RNA metabolism processes and human diseases Fang-tian Bu, Hai-yan Wang, Chao Xu, Kang-li Song, Zhen Dai, Lin-ting Wang, Jie Ying, Jianxiang Chen
Theranostics 2024; 14(12): 4683-4700. doi:10.7150/thno.99019
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Molecular imaging nanoprobes and their applications in atherosclerosis diagnosis Huari Kou, Hu Yang
Theranostics 2024; 14(12): 4747-4772. doi:10.7150/thno.96037
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The principles and promising future of sonogenetics for precision medicine Pengying Wu, Zhaoyou Liu, Wenxin Tao, Yubo Lai, Guodong Yang, Lijun Yuan
Theranostics 2024; 14(12): 4806-4821. doi:10.7150/thno.98476
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