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Volume 8 (8); 2018
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Reply to Kovacs et al.: Concerning acute inflammatory response following focused ultrasound and microbubbles in the brain 
 Dallan  McMahon, Kullervo  Hynynen 
 
Theranostics 2018;  8(8): 2249-2250. doi:10.7150/thno.25468 
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Editorials
OVOL2 in metastasis prevention in NPC 
 Kyung-A  Song, Anthony C.  Faber 
 
Theranostics 2018;  8(8): 2242-2244. doi:10.7150/thno.25181 
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Focused ultrasound with microbubbles induces sterile inflammatory response proportional to the blood brain barrier opening: Attention to experimental conditions 
 Zsofia I.  Kovacs, Scott R.  Burks, Joseph A.  Frank 
 
Theranostics 2018;  8(8): 2245-2248. doi:10.7150/thno.24181 
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Research Papers
 
Photoacoustic Imaging as an Early Biomarker of Radio Therapeutic Efficacy in Head and Neck Cancer 
 Laurie. J.  Rich, Austin  Miller, Anurag K.  Singh, Mukund  Seshadri 
 
Theranostics 2018;  8(8): 2064-2078. doi:10.7150/thno.21708 
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Coronary Serum Exosomes Derived from Patients with Myocardial Ischemia Regulate Angiogenesis through the miR-939-mediated Nitric Oxide Signaling Pathway 
 Hao  Li, Yiteng  Liao, Lei  Gao, Tao  Zhuang, Zheyong  Huang, Hongming  Zhu, Junbo  Ge 
 
Theranostics 2018;  8(8): 2079-2093. doi:10.7150/thno.21895 
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Development of a novel albumin-based and maleimidopropionic acid-conjugated peptide with prolonged half-life and increased in vivo anti-tumor efficacy 
 Junnan  Feng, Chuanke  Zhao, Lixin  Wang, Like  Qu, Hua  Zhu, Zhi  Yang, Guo  An, Huifang  Tian, Chengchao  Shou 
 
Theranostics 2018;  8(8): 2094-2106. doi:10.7150/thno.22069 
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Amino Acid Uptake Measured by [18F]AFETP Increases in Response to Arginine Starvation in ASS1-Deficient Sarcomas 
 Bethany Cheree  Prudner, Fangdi  Sun, Jeffrey Charles  Kremer, Jinbin  Xu, Chaofeng  Huang, Kiran Kumar Solingapuram  Sai, Zachary  Morgan, Hayden  Leeds, Jonathan  McConathy, Brian Andrew  Van Tine 
 
Theranostics 2018;  8(8): 2107-2116. doi:10.7150/thno.22083 
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3D Imaging and Quantitative Analysis of Vascular Networks: A Comparison of Ultramicroscopy and Micro-Computed Tomography 
 Jeremy  Epah, Katalin  Pálfi, Franziska Luise  Dienst, Pedro Felipe  Malacarne, Rolf  Bremer, Michael  Salamon, Sandeep  Kumar, Hanjoong  Jo, Christoph  Schürmann, Ralf Peter  Brandes 
 
Theranostics 2018;  8(8): 2117-2133. doi:10.7150/thno.22610 
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Enhancement of Cancer-Specific Protoporphyrin IX Fluorescence by Targeting Oncogenic Ras/MEK Pathway 
 Ema  Yoshioka, Vipin Shankar  Chelakkot, Maria  Licursi, Suzette G  Rutihinda, Jayoti  Som, Leena  Derwish, Justin J  King, Theerawat  Pongnopparat, Karen  Mearow, Mani  Larijani, Ann M  Dorward, Kensuke  Hirasawa 
 
Theranostics 2018;  8(8): 2134-2146. doi:10.7150/thno.22641 
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Release of MicroRNAs into Body Fluids from Ten Organs of Mice Exposed to Cigarette Smoke 
 Alberto  Izzotti, Mariagrazia  Longobardi, Sebastiano  La Maestra, Rosanna T.  Micale, Alessandra  Pulliero, Anna  Camoirano, Marta  Geretto, Francesco  D'Agostini, Roumen  Balansky, Mark Steven  Miller, Vernon E.  Steele, Silvio  De Flora 
 
Theranostics 2018;  8(8): 2147-2160. doi:10.7150/thno.22726 
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Tumor-targeted Dual-modality Imaging to Improve Intraoperative Visualization of Clear Cell Renal Cell Carcinoma: A First in Man Study 
 Marlène C.  Hekman, Mark  Rijpkema, Constantijn H.  Muselaers, Egbert  Oosterwijk, Christina A.  Hulsbergen-Van de Kaa, Otto C.  Boerman, Wim J.  Oyen, Johan F.  Langenhuijsen, Peter F.  Mulders 
 
Theranostics 2018;  8(8): 2161-2170. doi:10.7150/thno.23335 
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Adipocyte-Derived Exosomal MiR-27a Induces Insulin Resistance in Skeletal Muscle Through Repression of PPARγ 
 Yang  Yu, Hongwei  Du, Shengnan  Wei, Linjing  Feng, Junnan  Li, Fan  Yao, Ming  Zhang, Grant M.  Hatch, Li  Chen 
 
Theranostics 2018;  8(8): 2171-2188. doi:10.7150/thno.22565 
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Glucocorticoids Inhibit Oncogenic RUNX1-ETO in Acute Myeloid Leukemia with Chromosome Translocation t(8;21) 
 Lianghao  Lu, Yefei  Wen, Yuan  Yao, Fengju  Chen, Guohui  Wang, Fangrui  Wu, Jingyu  Wu, Padmini  Narayanan, Michele  Redell, Qianxing  Mo, Yongcheng  Song 
 
Theranostics 2018;  8(8): 2189-2201. doi:10.7150/thno.22800 
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OVOL2 links stemness and metastasis via fine-tuning epithelial-mesenchymal transition in nasopharyngeal carcinoma 
 Xue-Kang  Qi, Hui-Qiong  Han, Hao-Jiong  Zhang, Miao  Xu, Lili  Li, Lin  Chen, Tong  Xiang, Qi-Sheng  Feng, Tiebang  Kang, Chao-Nan  Qian, Mu-Yan  Cai, Qian  Tao, Yi-Xin  Zeng, Lin  Feng 
 
Theranostics 2018;  8(8): 2202-2216. doi:10.7150/thno.24003 
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Polyamine-Targeting Gefitinib Prodrug and its Near-Infrared Fluorescent Theranostic Derivative for Monitoring Drug Delivery and Lung Cancer Therapy 
 Xinyu  Song, Xiaoyue  Han, Fabiao  Yu, Xiaoyu  Zhang, Lingxin  Chen, Changjun  Lv 
 
Theranostics 2018;  8(8): 2217-2228. doi:10.7150/thno.24041 
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Combining photothermal therapy and immunotherapy against melanoma by polydopamine-coated Al2O3 nanoparticles 
 Wenfei  Chen, Ming  Qin, Xiaoyan  Chen, Qin  Wang, Zhirong  Zhang, Xun  Sun 
 
Theranostics 2018;  8(8): 2229-2241. doi:10.7150/thno.24073 
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Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome 
 Guangxue  Wang, Michael  Gormley, Jing  Qiao, Qian  Zhao, Min  Wang, Gabriele  Di Sante, Shengqiong  Deng, Lin  Dong, Tim  Pestell, Xiaoming  Ju, Mathew C.  Casimiro, Sankar  Addya, Paolo  Fortina, Ayden  Tozeren, Qinchuan  Li, Zuoren  Yu, Richard G.  Pestell 
 
Theranostics 2018;  8(8): 2251-2263. doi:10.7150/thno.23877 
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Localized delivery of curcumin into brain with polysorbate 80-modified cerasomes by ultrasound-targeted microbubble destruction for improved Parkinson's disease therapy 
 Nisi  Zhang, Fei  Yan, Xiaolong  Liang, Manxiang  Wu, Yuanyuan  Shen, Min  Chen, Yunxue  Xu, Guangyang  Zou, Peng  Jiang, Caiyun  Tang, Hairong  Zheng, Zhifei  Dai 
 
Theranostics 2018;  8(8): 2264-2277. doi:10.7150/thno.23734 
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DNA Methylation Signatures Predicting Bevacizumab Efficacy in Metastatic Breast Cancer 
 Simon Peter  Gampenrieder, Gabriel  Rinnerthaler, Hubert  Hackl, Walter  Pulverer, Andreas  Weinhaeusel, Suzana  Ilic, Clemens  Hufnagl, Cornelia  Hauser-Kronberger, Alexander  Egle, Angela  Risch, Richard  Greil 
 
Theranostics 2018;  8(8): 2278-2288. doi:10.7150/thno.23544 
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Paper-based electrochemiluminescence sensor for highly sensitive detection of amyloid-β oligomerization: Toward potential diagnosis of Alzheimer's disease 
 Hongxing  Liu, Xiaoming  Zhou, Qi  Shen, Da  Xing 
 
Theranostics 2018;  8(8): 2289-2299. doi:10.7150/thno.23483 
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