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Volume 7 (17); 2017

Research Paper

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Transforming doxorubicin into a cancer stem cell killer via EpCAM aptamer-mediated delivery
Dongxi Xiang, Sarah Shigdar, Andrew G Bean, Matthew Bruce, Wenrong Yang, Motilal Mathesh, Tao Wang, Wang Yin, Phuong Ha-Lien Tran, Hadi Al Shamaileh, Roberto A Barrero, Pei-Zhuo Zhang, Yong Li, Lingxue Kong, Ke Liu, Shu-Feng Zhou, Yingchun Hou, Aina He, Wei Duan
Theranostics 2017; 7(17): 4071-4086. doi:10.7150/thno.20168
[Abstract] [Full text] [PDF]


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Enhanced Radiotherapy using Bismuth Sulfide Nanoagents Combined with Photo-thermal Treatment
Xiaju Cheng, Yuan Yong, Yiheng Dai, Xin Song, Gang Yang, Yue Pan, Cuicui Ge
Theranostics 2017; 7(17): 4087-4098. doi:10.7150/thno.20548
[Abstract] [Full text] [PDF]


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Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma
A. Villasante, K. Sakaguchi, J. Kim, N.K. Cheung, M. Nakayama, H. Parsa, T. Okano, T. Shimizu, G. Vunjak-Novakovic
Theranostics 2017; 7(17): 4099-4117. doi:10.7150/thno.20730
[Abstract] [Full text] [PDF]


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DNA Methylation of miR-7 is a Mechanism Involved in Platinum Response through MAFG Overexpression in Cancer Cells
Olga Vera, Julia Jimenez, Olga Pernia, Carlos Rodriguez-Antolin, Carmen Rodriguez, Fatima Sanchez Cabo, Javier Soto, Rocio Rosas, Sara Lopez-Magallon, Isabel Esteban Rodriguez, Ana Dopazo, Federico Rojo, Cristobal Belda, Rafael Alvarez, Jaime Valentin, Javier Benitez, Rosario Perona, Javier De Castro, Inmaculada Ibanez de Caceres
Theranostics 2017; 7(17): 4118-4134. doi:10.7150/thno.20112
[Abstract] [Full text] [PDF]


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Tethering Interleukin-22 to Apolipoprotein A-I Ameliorates Mice from Acetaminophen-induced Liver Injury
Wei Chen, Xuyao Zhang, Jiajun Fan, Wenjing Zai, Jingyun Luan, Yubin Li, Shaofei Wang, Qicheng Chen, Yichen Wang, Yanxu Liang, Dianwen Ju
Theranostics 2017; 7(17): 4135-4148. doi:10.7150/thno.20955
[Abstract] [Full text] [PDF]


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Dual-targeting Theranostic System with Mimicking Apoptosis to Promote Myocardial Infarction Repair via Modulation of Macrophages
Jingli Chen, Jun Yang, Ruiyuan Liu, Chenmeng Qiao, Zhiguo Lu, Yuanjie Shi, Zhanming Fan, Zhenzhong Zhang, Xin Zhang
Theranostics 2017; 7(17): 4149-4167. doi:10.7150/thno.21040
[Abstract] [Full text] [PDF]


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Pro-Inflammatory CXCR3 Impairs Mitochondrial Function in Experimental Non-Alcoholic Steatohepatitis
Jinghua Du, Xiang Zhang, Juqiang Han, Kwan Man, Yanquan Zhang, Eagle SH Chu, Yuemin Nan, Jun Yu
Theranostics 2017; 7(17): 4192-4203. doi:10.7150/thno.21400
[Abstract] [Full text] [PDF]


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pH-Sensitive Nano-Complexes Overcome Drug Resistance and Inhibit Metastasis of Breast Cancer by Silencing Akt Expression
Jieying Yin, Tianqun Lang, Dongmei Cun, Zhong Zheng, Yan Huang, Qi Yin, Haijun Yu, Yaping Li
Theranostics 2017; 7(17): 4204-4216. doi:10.7150/thno.21516
[Abstract] [Full text] [PDF]


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Ultra-small pH-responsive Nd-doped NaDyF4 Nanoagents for Enhanced Cancer Theranostic by in situ Aggregation
Yuxin Liu, Huimin Fan, Quanwei Guo, Anqi Jiang, Xiaoxia Du, Jing Zhou
Theranostics 2017; 7(17): 4217-4228. doi:10.7150/thno.21557
[Abstract] [Full text] [PDF]


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Liposomal 64Cu-PET Imaging of Anti-VEGF Drug Effects on Liposomal Delivery to Colon Cancer Xenografts
Stephanie J. Blocker, Kirk A. Douglas, Lisa Anne Polin, Helen Lee, Bart S. Hendriks, Enxhi Lalo, Wei Chen, Anthony F. Shields
Theranostics 2017; 7(17): 4229-4239. doi:10.7150/thno.21688
[Abstract] [Full text] [PDF]


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Engineered Zn(II)-Dipicolylamine-Gold Nanorod Provides Effective Prostate Cancer Treatment by Combining siRNA Delivery and Photothermal Therapy
Kyung Hyun Min, Young-Hwa Kim, Zhantong Wang, Jihoon Kim, Jee Seon Kim, Sun Hwa Kim, Kwangmeyung Kim, Ick Chan Kwon, Dale O. Kiesewetter, Xiaoyuan Chen
Theranostics 2017; 7(17): 4240-4254. doi:10.7150/thno.22435
[Abstract] [Full text] [PDF]


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Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice
Chao Li, Yiping Lu, Sitong Du, Siyi Li, Yiting Zhang, Fangwei Liu, Ying Chen, Dong Weng, Jie Chen
Theranostics 2017; 7(17): 4255-4275. doi:10.7150/thno.20270
[Abstract] [Full text] [PDF]


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Noninvasive Imaging of CD206-Positive M2 Macrophages as an Early Biomarker for Post-Chemotherapy Tumor Relapse and Lymph Node Metastasis
Chenran Zhang, Xinhe Yu, Liquan Gao, Yang Zhao, Jianhao Lai, Dehua Lu, Rui Bao, Bing Jia, Lijun Zhong, Fan Wang, Zhaofei Liu
Theranostics 2017; 7(17): 4276-4288. doi:10.7150/thno.20999
[Abstract] [Full text] [PDF]


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Label-Free Biochips for Accurate Detection of Prostate Cancer in the Clinic: Dual Biomarkers and Circulating Tumor Cells
Lung-Hsuan Pan, See-Tong Pang, Po-Yu Fang, Cheng-Keng Chuang, Hung-Wei Yang
Theranostics 2017; 7(17): 4289-4300. doi:10.7150/thno.21092
[Abstract] [Full text] [PDF]


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Long-term Effect of Biomineralized Insulin Nanoparticles on Type 2 Diabetes Treatment
Yun Xiao, Xiaoyu Wang, Ben Wang, Xueyao Liu, Xurong Xu, Ruikang Tang
Theranostics 2017; 7(17): 4301-4312. doi:10.7150/thno.21450
[Abstract] [Full text] [PDF]


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Sustained Release Talazoparib Implants for Localized Treatment of BRCA1-deficient Breast Cancer
Jodi E. Belz, Rajiv Kumar, Paige Baldwin, Noelle Castilla Ojo, Ana S. Leal, Darlene B. Royce, Di Zhang, Anne L. van de Ven, Karen T. Liby, Srinivas Sridhar
Theranostics 2017; 7(17): 4340-4349. doi:10.7150/thno.18563
[Abstract] [Full text] [PDF]

Review

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Extracellular Vesicles in Cardiovascular Theranostics
Yihua Bei, Saumya Das, Rodosthenis S. Rodosthenous, Paul Holvoet, Maarten Vanhaverbeke, Marta Chagas Monteiro, Valter Vinicius Silva Monteiro, Jana Radosinska, Monika Bartekova, Felix Jansen, Qian Li, Johnson Rajasingh, Junjie Xiao
Theranostics 2017; 7(17): 4168-4182. doi:10.7150/thno.21274
[Abstract] [Full text] [PDF]


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Identifying and Characterizing circRNA-Protein Interaction
William W Du, Chao Zhang, Weining Yang, Tianqiao Yong, Faryal Mehwish Awan, Burton B Yang
Theranostics 2017; 7(17): 4183-4191. doi:10.7150/thno.21299
[Abstract] [Full text] [PDF]


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Oral Microbiome: A New Biomarker Reservoir for Oral and Oropharyngeal Cancers
Yenkai Lim, Makrina Totsika, Mark Morrison, Chamindie Punyadeera
Theranostics 2017; 7(17): 4313-4321. doi:10.7150/thno.21804
[Abstract] [Full text] [PDF]


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Past, Present, and Future: Development of Theranostic Agents Targeting Carbonic Anhydrase IX
Joseph Lau, Kuo-Shyan Lin, François Bénard
Theranostics 2017; 7(17): 4322-4339. doi:10.7150/thno.21848
[Abstract] [Full text] [PDF]