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Volume 7 (16); 2017

Editorial

Oxygen breathing challenge- the simplest theranostic
Ralph P. Mason
Theranostics 2017; 7(16): 3873-3875. doi:10.7150/thno.20655
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Emerging Advances in Nanotheranostics with Intelligent Bioresponsive Systems
Junqing Wang, Wei Tao, Xiaoyuan Chen, Omid C. Farokhzad, Gang Liu
Theranostics 2017; 7(16): 3915-3919. doi:10.7150/thno.21317
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper

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Serum Immune Profiling for Early Detection of Cervical Disease
Radwa Ewaisha, Gitika Panicker, Paul Maranian, Elizabeth R. Unger, Karen S. Anderson
Theranostics 2017; 7(16): 3814-3823. doi:10.7150/thno.21098
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Metabolomic Profiling of Extracellular Vesicles and Alternative Normalization Methods Reveal Enriched Metabolites and Strategies to Study Prostate Cancer-Related Changes
Maija Puhka, Maarit Takatalo, Maria-Elisa Nordberg, Sami Valkonen, Jatin Nandania, Maria Aatonen, Marjo Yliperttula, Saara Laitinen, Vidya Velagapudi, Tuomas Mirtti, Olli Kallioniemi, Antti Rannikko, Pia R-M Siljander, Taija Maria af Hällström
Theranostics 2017; 7(16): 3824-3841. doi:10.7150/thno.19890
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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A Circular RNA Binds To and Activates AKT Phosphorylation and Nuclear Localization Reducing Apoptosis and Enhancing Cardiac Repair
Yan Zeng, William W. Du, Yingya Wu, Zhenguo Yang, Faryal Mehwish Awan, Xiangmin Li, Weining Yang, Chao Zhang, Qi Yang, Albert Yee, Yu Chen, Fenghua Yang, Huan Sun, Ren Huang, Albert J Yee, Ren-Ke Li, Zhongkai Wu, Peter H Backx, Burton B Yang
Theranostics 2017; 7(16): 3842-3855. doi:10.7150/thno.19764
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Berunda Polypeptides: Multi-Headed Fusion Proteins Promote Subcutaneous Administration of Rapamycin to Breast Cancer In Vivo
Jugal P. Dhandhukia, Zhe Li, Santosh Peddi, Shruti Kakan, Arjun Mehta, David Tyrpak, Jordan Despanie, J. Andrew MacKay
Theranostics 2017; 7(16): 3856-3872. doi:10.7150/thno.19981
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Multimodal Assessment of Mesenchymal Stem Cell Therapy for Diabetic Vascular Complications
Jamila Hedhli, Christian J. Konopka, Sarah Schuh, Hannah Bouvin, John A. Cole, Heather D. Huntsman, Kristopher A. Kilian, Iwona T. Dobrucki, Marni D. Boppart, Lawrence W. Dobrucki
Theranostics 2017; 7(16): 3876-3888. doi:10.7150/thno.19547
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Overexpression of miR-194 Reverses HMGA2-driven Signatures in Colorectal Cancer
Hsin-Yi Chang, Shu-Ping Ye, Shiow-Lin Pan, Tzu-Ting Kuo, Bia Chia Liu, Yi-Lin Chen, Tsui-Chin Huang
Theranostics 2017; 7(16): 3889-3900. doi:10.7150/thno.20041
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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“One-Pot” Fabrication of Highly Versatile and Biocompatible Poly(vinyl alcohol)-porphyrin-based Nanotheranostics
Yan Luo, Hao Wu, Caihong Feng, Kai Xiao, Xixiao Yang, Qiangqiang Liu, Tzu-yin Lin, Hongyong Zhang, Jeffrey H. Walton, Yousif Ajena, Yide Hu, Kit S. Lam, Yuanpei Li
Theranostics 2017; 7(16): 3901-3914. doi:10.7150/thno.20190
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Decrease in Lymphoid Specific Helicase and 5-hydroxymethylcytosine Is Associated with Metastasis and Genome Instability
Jiantao Jia, Ying Shi, Ling Chen, Weiwei Lai, Bin Yan, Yiqun Jiang, Desheng Xiao, Sichuan Xi, Ya Cao, Shuang Liu, Yan Cheng, Yongguang Tao
Theranostics 2017; 7(16): 3920-3932. doi:10.7150/thno.21389
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Can molecular profiling enhance radiotherapy? Impact of personalized targeted gold nanoparticles on radiosensitivity and imaging of adenoid cystic carcinoma
Inbal Hazkani, Menachem Motiei, Oshra Betzer, Tamar Sadan, Dimitri Bragilovski, Leon Lubimov, Aviram Mizrachi, Tuvia Hadar, Mattan Levi, Irit Ben-Aharon, Izhack Haviv, Rachela Popovtzer, Aron Popovtzer
Theranostics 2017; 7(16): 3962-3971. doi:10.7150/thno.19615
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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MiR-205/YAP1 in Activated Fibroblasts of Breast Tumor Promotes VEGF-independent Angiogenesis through STAT3 Signaling
Yan-e Du, Gang Tu, Guanglun Yang, Genyou Li, Dan Yang, Lei Lang, Lei Xi, Kexin Sun, Yanlin Chen, Kunxian Shu, Huadong Liao, Manran Liu, Yixuan Hou
Theranostics 2017; 7(16): 3972-3988. doi:10.7150/thno.18990
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Acute Inflammatory Response Following Increased Blood-Brain Barrier Permeability Induced by Focused Ultrasound is Dependent on Microbubble Dose
Dallan McMahon, Kullervo Hynynen
Theranostics 2017; 7(16): 3989-4000. doi:10.7150/thno.21630
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Ginsenoside Rg1 Inhibits Glucagon-Induced Hepatic Gluconeogenesis through Akt-FoxO1 Interaction
Qun Liu, Fei-Ge Zhang, Wen-Song Zhang, An Pan, Yi-Lin Yang, Jin-Feng Liu, Ping Li, Bao-Lin Liu, Lian-Wen Qi
Theranostics 2017; 7(16): 4001-4012. doi:10.7150/thno.18788
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The Use of PET Imaging for Prognostic Integrin α2β1 Phenotyping to Detect Non-Small Cell Lung Cancer and Monitor Drug Resistance Responses
Chiun-Wei Huang, Wen-Chuan Hsieh, Shih-Ting Hsu, Yi-Wen Lin, Yi-Hsiu Chung, Wen-Chi Chang, Han Chiu, Yun Han Lin, Chung-Pu Wu, Tzu-Chen Yen, Feng-Ting Huang
Theranostics 2017; 7(16): 4013-4028. doi:10.7150/thno.19304
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Investigating the Effect of Chemical Structure of Semiconducting Polymer Nanoparticle on Photothermal Therapy and Photoacoustic Imaging
Dongdong Li, Guobing Zhang, Weiguo Xu, Junxia Wang, Yucai Wang, Longzhen Qiu, Jianxun Ding, Xianzhu Yang
Theranostics 2017; 7(16): 4029-4040. doi:10.7150/thno.19538
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Notch3 Maintains Luminal Phenotype and Suppresses Tumorigenesis and Metastasis of Breast Cancer via Trans-Activating Estrogen Receptor-α
Xiao-Wei Dou, Yuan-Ke Liang, Hao-Yu Lin, Xiao-Long Wei, Yong-Qu Zhang, Jing-Wen Bai, Chun-Fa Chen, Min Chen, Cai-Wen Du, Yao-Chen Li, Jie Tian, Kwan Man, Guo-Jun Zhang
Theranostics 2017; 7(16): 4041-4056. doi:10.7150/thno.19989
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Multiplexed Nucleic Acid Programmable Protein Arrays
Xiaobo Yu, Lusheng Song, Brianne Petritis, Xiaofang Bian, Haoyu Wang, Jennifer Viloria, Jin Park, Hoang Bui, Han Li, Jie Wang, Lei Liu, Liuhui Yang, Hu Duan, David N. McMurray, Jacqueline M. Achkar, Mitch Magee, Ji Qiu, Joshua LaBaer
Theranostics 2017; 7(16): 4057-4070. doi:10.7150/thno.20151
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

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Nucleic Acid-Based Theranostics for Tackling Alzheimer's Disease
Madhuri Chakravarthy, Suxiang Chen, Peter R. Dodd, Rakesh N. Veedu
Theranostics 2017; 7(16): 3933-3947. doi:10.7150/thno.21529
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Aptamer-Based Therapeutic Approaches to Target Cancer Stem Cells
Gang Zhou, Olivier Latchoumanin, Mary Bagdesar, Lionel Hebbard, Wei Duan, Christopher Liddle, Jacob George, Liang Qiao
Theranostics 2017; 7(16): 3948-3961. doi:10.7150/thno.20725
[Abstract] [Full text] [PDF] [PubMed] [PMC]