Cover image

Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


toc.jpg

Research Paper
Dual turn-on fluorescence signal-based controlled release system for real-time monitoring of drug release dynamics in living cells and tumor tissues
Xiuqi Kong, Baoli Dong, Xuezhen Song, Chao Wang, Nan Zhang, Weiying Lin
Theranostics 2018; 8(3): 800-811. doi:10.7150/thno.21577
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
131I-Labeled Copper Sulfide-Loaded Microspheres to Treat Hepatic Tumors via Hepatic Artery Embolization
Qiufang Liu, Yuyi Qian, Panli Li, Sihang Zhang, Jianjun Liu, Xiaoguang Sun, Michael Fulham, Dagan Feng, Gang Huang, Wei Lu, Shaoli Song
Theranostics 2018; 8(3): 785-799. doi:10.7150/thno.21491
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
A Tumor-Activatable Theranostic Nanomedicine Platform for NIR Fluorescence-Guided Surgery and Combinatorial Phototherapy
Xiaoning Li, Canan Schumann, Hassan A. Albarqi, Christopher J. Lee, Adam W. G. Alani, Shay Bracha, Milan Milovancev, Olena Taratula, Oleh Taratula
Theranostics 2018; 8(3): 767-784. doi:10.7150/thno.21209
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Atherosclerosis is exacerbated by chitinase-3-like-1 in amyloid precursor protein transgenic mice
Yu Yeon Jung, Ki Cheon Kim, Mi Hee Park, Youngsik Seo, Heonyong Park, Min Hee Park, Jun Chang, Dae Youn Hwang, Sang Bae Han, Sanghyeon Kim, Dong Ju Son, Jin Tae Hong
Theranostics 2018; 8(3): 749-766. doi:10.7150/thno.20183
[Abstract] [Full text] [PDF]


Erratum
Improvement of Prostate Cancer Diagnosis by Detecting PSA Glycosylation-Specific Changes: Erratum
Esther Llop, Montserrat Ferrer-Batallé, Sílvia Barrabés, Pedro Enrique Guerrero, Manel Ramírez, Radka Saldova, Pauline M. Rudd, Rosa N. Aleixandre, Josep Comet, Rafael de Llorens, Rosa Peracaula
Theranostics 2018; 8(3): 746-748. doi:10.7150/thno.23906
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Evans Blue Attachment Enhances Somatostatin Receptor Subtype-2 Imaging and Radiotherapy
Rui Tian, Orit Jacobson, Gang Niu, Dale O. Kiesewetter, Zhantong Wang, Guizhi Zhu, Ying Ma, Gang Liu, Xiaoyuan Chen
Theranostics 2018; 8(3): 735-745. doi:10.7150/thno.23491
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice
Volker Neuschmelting, Kwanghee Kim, Jaber Malekzadeh-Najafabadi, Sylvia Jebiwott, Jaya Prakash, Avigdor Scherz, Jonathan A. Coleman, Moritz F. Kircher, Vasilis Ntziachristos
Theranostics 2018; 8(3): 723-734. doi:10.7150/thno.20386
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
General Anesthesia Inhibits the Activity of the “Glymphatic System”
Clement Gakuba, Thomas Gaberel, Suzanne Goursaud, Jennifer Bourges, Camille Di Palma, Aurélien Quenault, Sara Martinez de Lizarrondo, Denis Vivien, Maxime Gauberti
Theranostics 2018; 8(3): 710-722. doi:10.7150/thno.19154
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Enhanced Synergism of Thermo-chemotherapy For Liver Cancer with Magnetothermally Responsive Nanocarriers
Minghua Li, Wenbo Bu, Jie Ren, Jianbo Li, Li Deng, Mingyuan Gao, Xiaolong Gao, Peijun Wang
Theranostics 2018; 8(3): 693-709. doi:10.7150/thno.21297
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer
Hong ZHU, Lin-Lin CHANG, Fang-Jie YAN, Yan HU, Chen-Ming ZENG, Tian-Yi ZHOU, Tao YUAN, Mei-Dan YING, Ji CAO, Qiao-Jun HE, Bo YANG
Theranostics 2018; 8(3): 676-692. doi:10.7150/thno.21463
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Mesoporous Carbon Nanospheres as a Multifunctional Carrier for Cancer Theranostics
Libo Zhou, Ying Jing, Yubin Liu, Zhihe Liu, Duyang Gao, Haobin Chen, Weiye Song, Tao Wang, Xiaofeng Fang, Weiping Qin, Zhen Yuan, Sheng Dai, Zhen-An Qiao, Changfeng Wu
Theranostics 2018; 8(3): 663-675. doi:10.7150/thno.21927
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
CDK16 Phosphorylates and Degrades p53 to Promote Radioresistance and Predicts Prognosis in Lung Cancer
Jie Xie, Yan Li, Ke Jiang, Kaishun Hu, Sheng Zhang, Xiaorong Dong, Xiaofang Dai, Li Liu, Tao Zhang, Kunyu Yang, Kai Huang, Junjie Chen, Shaojun Shi, Yu Zhang, Gang Wu, Shuangbing Xu
Theranostics 2018; 8(3): 650-662. doi:10.7150/thno.21963
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Peptide receptor radionuclide therapy as a new tool in treatment-refractory sarcoidosis - initial experience in two patients
Constantin Lapa, Malte Kircher, Heribert Hänscheid, Andreas Schirbel, Götz Ulrich Grigoleit, Erdwine Klinker, Markus Böck, Samuel Samnick, Theo Pelzer, Andreas K Buck
Theranostics 2018; 8(3): 644-649. doi:10.7150/thno.22161
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Cardiomyocyte-Restricted Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Deletion Leads to Lethal Dilated Cardiomyopathy Partly Through Drp1 Signaling
Zhidan Chen, Yang Li, Ying Wang, Juying Qian, Hong Ma, Xiang Wang, Guoliang Jiang, Ming Liu, Yanpeng An, Leilei Ma, Le Kang, Jianguo Jia, Chunjie Yang, Guoping Zhang, Ying Chen, Wei Gao, Mingqiang Fu, Zheyong Huang, Huiru Tang, Yichun Zhu, Junbo Ge, Hui Gong, Yunzeng Zou
Theranostics 2018; 8(3): 627-643. doi:10.7150/thno.22177
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α
Feng Zhang, Shuai Lu, Jianlin He, Huanhuan Jin, Feixia Wang, Li Wu, Jiangjuan Shao, Anping Chen, Shizhong Zheng
Theranostics 2018; 8(3): 610-626. doi:10.7150/thno.22237
[Abstract] [Full text] [PDF]


toc.jpg

Review
Galectin-3 Activation and Inhibition in Heart Failure and Cardiovascular Disease: An Update
Navin Suthahar, Wouter C. Meijers, Herman H.W. Silljé, Jennifer E. Ho, Fu-Tong Liu, Rudolf A. de Boer
Theranostics 2018; 8(3): 593-609. doi:10.7150/thno.22196
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

new Nanotheranostics in PubMed Central

Theme Issue on “Brain Theranostics. Guest Editor: Prof. Rachela Popovtzer, PhD
Cover image
Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues