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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
Therapeutic Inhibition of miR-4260 Suppresses Colorectal Cancer via Targeting MCC and SMAD4
Junjie Xiao, Dongchao Lv, Jinzhe Zhou, Yihua Bei, Ting Chen, Muren Hu, Qiulian Zhou, Siyi Fu, Qi Huang
Theranostics 2017; 7(7): 1901-1913. doi:10.7150/thno.19168
[Abstract] [Full text] [PDF]


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Research Paper
Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia
Lifeng Feng, Jiaqiu Li, Lixian Yang, Libo Zhu, Xiufeng Huang, Shuzheng Zhang, Likang Luo, Zhinong Jiang, Tingting Jiang, Wenxia Xu, Xian Wang, Hongchuan Jin
Theranostics 2017; 7(7): 1890-1900. doi:10.7150/thno.19135
[Abstract] [Full text] [PDF]


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Research Paper
Self-Assembly of Gold Nanoparticles Shows Microenvironment-Mediated Dynamic Switching and Enhanced Brain Tumor Targeting
Qishuai Feng, Yajing Shen, Yingjie Fu, Megan E. Muroski, Peng Zhang, Qiaoyue Wang, Chang Xu, Maciej S. Lesniak, Gang Li, Yu Cheng
Theranostics 2017; 7(7): 1875-1889. doi:10.7150/thno.18985
[Abstract] [Full text] [PDF]


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Research Paper
Rapid fluorescence imaging of spinal cord following epidural administration of a nerve-highlighting fluorophore
Wanguo Liu, Rui Gu, Qingsan Zhu, Chunsheng Xiao, Lanfeng Huang, Xinming Zhuang, Jingzhe Zhang, Lidi Liu, Ben Ma, Huailin Yang, Jianchao Ma, Zhipeng Hu, Chenglin Tang, Shuhua Zhao, Xuesi Chen
Theranostics 2017; 7(7): 1863-1874. doi:10.7150/thno.18962
[Abstract] [Full text] [PDF]


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Review
Advances in the detection of telomerase activity using isothermal amplification
Xiaojin Zhang, Xiaoding Lou, Fan Xia
Theranostics 2017; 7(7): 1847-1862. doi:10.7150/thno.18930
[Abstract] [Full text] [PDF]


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Research Paper
Rapid Detection of Avian Influenza Virus by Fluorescent Diagnostic Assay using an Epitope-Derived Peptide
Duong Tuan Bao, Do Thi Hoang Kim, Hyun Park, Bui Thi Cuc, Nguyen Minh Ngoc, Nguyen Thi Phuong Linh, Nguyen Chien Huu, Trinh Thi Thuy Tien, Nguyen Thi Viet Anh, Tung Dao Duy, Chom-Kyu Chong, Seung-Taek Yu, Do-Young Choi, Seon-Ju Yeo
Theranostics 2017; 7(7): 1835-1846. doi:10.7150/thno.18857
[Abstract] [Full text] [PDF]


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Research Paper
Bright Polymer Dots Tracking Stem Cell Engraftment and Migration to Injured Mouse Liver
Dandan Chen, Qiong Li, Zihui Meng, Lei Guo, Ying Tang, Zhihe Liu, Shengyan Yin, Weiping Qin, Zhen Yuan, Xuanjun Zhang, Changfeng Wu
Theranostics 2017; 7(7): 1820-1834. doi:10.7150/thno.18614
[Abstract] [Full text] [PDF]


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Research Paper
Dual-pH Sensitive Charge-reversal Nanocomplex for Tumor-targeted Drug Delivery with Enhanced Anticancer Activity
Qing Zhou, Yilin Hou, Li Zhang, Jianlin Wang, Youbei Qiao, Songyan Guo, Li Fan, Tiehong Yang, Lin Zhu, Hong Wu
Theranostics 2017; 7(7): 1806-1819. doi:10.7150/thno.18607
[Abstract] [Full text] [PDF]


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Review
Current and emerging techniques for antibiotic susceptibility tests
Karan Syal, Manni Mo, Hui Yu, Rafael Iriya, Wenwen Jing, Sui Guodong, Shaopeng Wang, Thomas E. Grys, Shelley E. Haydel, Nongjian Tao
Theranostics 2017; 7(7): 1795-1805. doi:10.7150/thno.19217
[Abstract] [Full text] [PDF]


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Research Paper
Dual-Responsive Molecular Probe for Tumor Targeted Imaging and Photodynamic Therapy
Xiaoqing Meng, Yueting Yang, Lihua Zhou, li Zhang, Yalin Lv, Sanpeng Li, Yayun Wu, Mingbin Zheng, Wenjun Li, Guanhui Gao, Guanjun Deng, Tao Jiang, Dapeng Ni, Ping Gong, Lintao Cai
Theranostics 2017; 7(7): 1781-1794. doi:10.7150/thno.18437
[Abstract] [Full text] [PDF]


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Research Paper
Diagnostic Accuracy of Ga-68-HBED-CC-PSMA-Ligand-PET/CT before Salvage Lymph Node Dissection for Recurrent Prostate Cancer
Cordula A. Jilg, Vanessa Drendel, H. Christian Rischke, Teresa Beck, Werner Vach, Kathrin Schaal, Ulrich Wetterauer, Wolfgang Schultze-Seemann, Philipp T. Meyer
Theranostics 2017; 7(6): 1770-1780. doi:10.7150/thno.18421
[Abstract] [Full text] [PDF]


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Research Paper
SAK-HV Triggered a Short-period Lipid-lowering Biotherapy Based on the Energy Model of Liver Proliferation via a Novel Pathway
Chao Zhang, Zhiguang Huang, Haoran Jing, Wenliang Fu, Min Yuan, Wenrong Xia, Ling Cai, Xiangdong Gan, Yao Chen, Minji Zou, Minhui Long, Jiaxi Wang, Min Wang, Donggang Xu
Theranostics 2017; 7(6): 1749-1769. doi:10.7150/thno.18415
[Abstract] [Full text] [PDF]


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Research Paper
Elongated Nanoparticle Aggregates in Cancer Cells for Mechanical Destruction with Low Frequency Rotating Magnetic Field
Yajing Shen, Congyu Wu, Taro Q. P. Uyeda, Gustavo R. Plaza, Bin Liu, Yu Han, Maciej S. Lesniak, Yu Cheng
Theranostics 2017; 7(6): 1735-1748. doi:10.7150/thno.18352
[Abstract] [Full text] [PDF]


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Research Paper
Redox Responsive Hyaluronic Acid Nanogels for Treating RHAMM (CD168) Over-expressive Cancer, both Primary and Metastatic Tumors
Chenchen Yang, Cheng Li, Peng Zhang, Wei Wu, Xiqun Jiang
Theranostics 2017; 7(6): 1719-1734. doi:10.7150/thno.18340
[Abstract] [Full text] [PDF]


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Research Paper
Peptide vaccination in the presence of adjuvants in patients after hematopoietic stem cell transplantation with CD4+ T cell reconstitution elicits consistent CD8+ T cell responses
Michael Schmitt, Anita Schmitt, Markus Wiesneth, Angela Hückelhoven, Zeguang Wu, Jürgen Kuball, Lei Wang, Peter Schauwecker, Susanne Hofmann, Marlies Götz, Birgit Michels, Birgit Maccari, Patrick Wuchter, Volker Eckstein, Thomas Mertens, Paul Schnitzler, Hartmut Döhner, Anthony D. Ho, Donald W. Bunjes, Peter Dreger, Hubert Schrezenmeier, Jochen Greiner
Theranostics 2017; 7(6): 1705-1718. doi:10.7150/thno.18301
[Abstract] [Full text] [PDF]


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Research Paper
Tumor Penetrating Theranostic Nanoparticles for Enhancement of Targeted and Image-guided Drug Delivery into Peritoneal Tumors following Intraperitoneal Delivery
Ning Gao, Erica N. Bozeman, Weiping Qian, Liya Wang, Hongyu Chen, Malgorzata Lipowska, Charles A Staley, Y. Andrew Wang, Hui Mao, Lily Yang
Theranostics 2017; 7(6): 1689-1704. doi:10.7150/thno.18125
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile

new Impact factor is 8.854, according to 2016 release of Journal Citation Reports®. Congratulations!

new Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

Theme Issue on “Brain Theranostics. Guest Editor: Prof. Rachela Popovtzer, PhD
Theme Issue on “Stem Cell Theranostics. Guest Editors: Kristopher Kilian, PhD, and Deok-Ho Kim, PhD
Theme Issue on “Biomolecular and biomimetic materials for theranostics. Guest Editors: Haiyun Song, PhD, and Chunhai Fan, PhD
Theme Issue on “Translational theranostics for infectious diseases. Guest Editor: Dr. Tony Y. Hu, Houston Methodist Research Institute
Theme Issue on “Light-Mediated Deep-Tissue Theranostics. Guest Editors: Dr. Gang Han, University of Massachusetts Medical School, and Dr. Jin Xie, University of Georgia
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Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...
new Congratulations to Dr. Chen for receiving the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.
NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues