Cover image

Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


Editorial
Listening in on the Microbubble Crowd: Advanced Acoustic Monitoring for Improved Control of Blood-Brain Barrier Opening with Focused Ultrasound
Catherine M. Gorick, Natasha D. Sheybani, Colleen T. Curley, Richard J. Price
Theranostics 2018; 8(11): 2988-2991. doi:10.7150/thno.26025
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Platinum-Based Nanovectors Engineered with Immuno-Modulating Adjuvant for Inhibiting Tumor growth and Promoting Immunity
Lisha Liu, Qinjun Chen, Chunhui Ruan, Xinli Chen, Yu Zhang, Xi He, Yujie Zhang, Yifei Lu, Qin Guo, Tao Sun, Hao Wang, Chen Jiang
Theranostics 2018; 8(11): 2974-2987. doi:10.7150/thno.24110
[Abstract] [Full text] [PDF]


toc.jpg

Review
Multimodality reporter gene imaging: Construction strategies and application
Mengting Li, Yichun Wang, Mei Liu, Xiaoli Lan
Theranostics 2018; 8(11): 2954-2973. doi:10.7150/thno.24108
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Cascade-amplifying synergistic effects of chemo-photodynamic therapy using ROS-responsive polymeric nanocarriers
Chun-Yang Sun, Ziyang Cao, Xue-Jun Zhang, Rong Sun, Chun-Shui Yu, Xianzhu Yang
Theranostics 2018; 8(11): 2939-2953. doi:10.7150/thno.24015
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Histone deacetylase 6 modulates macrophage infiltration during inflammation
Bing Yan, Songbo Xie, Yang Liu, Wenxuan Liu, Dengwen Li, Min Liu, Hongbo R. Luo, Jun Zhou
Theranostics 2018; 8(11): 2927-2938. doi:10.7150/thno.25317
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Three-dimensional transcranial microbubble imaging for guiding volumetric ultrasound-mediated blood-brain barrier opening
Ryan M. Jones, Lulu Deng, Kogee Leung, Dallan McMahon, Meaghan A. O'Reilly, Kullervo Hynynen
Theranostics 2018; 8(11): 2909-2926. doi:10.7150/thno.24911
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting
Maximilian Klingler, Clemens Decristoforo, Christine Rangger, Dominik Summer, Julie Foster, Jane K Sosabowski, Elisabeth von Guggenberg
Theranostics 2018; 8(11): 2896-2908. doi:10.7150/thno.24378
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
G9a stimulates CRC growth by inducing p53 Lys373 dimethylation-dependent activation of Plk1
Jie Zhang, Yafang Wang, Yanyan Shen, Pengxing He, Jian Ding, Yi Chen
Theranostics 2018; 8(10): 2884-2895. doi:10.7150/thno.23824
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
MicroRNA-193b-3p regulates chondrogenesis and chondrocyte metabolism by targeting HDAC3
Fangang Meng, Zhiwen Li, Zhiqi Zhang, Zibo Yang, Yan Kang, Xiaoyi Zhao, Dianbo Long, Shu Hu, Minghui Gu, Suiwen He, Peihui Wu, Zongkun Chang, Aishan He, Weiming Liao
Theranostics 2018; 8(10): 2862-2883. doi:10.7150/thno.23547
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Long non-coding RNAs AC026904.1 and UCA1: a “one-two punch” for TGF-β-induced SNAI2 activation and epithelial-mesenchymal transition in breast cancer
Guo-Yin Li, Wei Wang, Jian-Yong Sun, Bo Xin, Xiang Zhang, Ting Wang, Qian-Feng Zhang, Li-Bo Yao, Hua Han, Dai-Ming Fan, An-Gang Yang, Lin-Tao Jia, Lei Wang
Theranostics 2018; 8(10): 2846-2861. doi:10.7150/thno.23463
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Targeting intracellular MMPs efficiently inhibits tumor metastasis and angiogenesis
Yaqi Lv, Xiangmei Zhao, Lidan Zhu, Sijia Li, Qingqing Xiao, Wei He, Lifang Yin
Theranostics 2018; 8(10): 2830-2845. doi:10.7150/thno.23209
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Long noncoding RNA miR503HG, a prognostic indicator, inhibits tumor metastasis by regulating the HNRNPA2B1/NF-κB pathway in hepatocellular carcinoma
Hui Wang, Linhui Liang, Qiongzhu Dong, Lin Huan, Jia He, Botai Li, Chen Yang, Haojie Jin, Lin Wei, Chengtao Yu, Fangyu Zhao, Jinjun Li, Ming Yao, Wenxin Qin, Lunxiu Qin, Xianghuo He
Theranostics 2018; 8(10): 2814-2829. doi:10.7150/thno.23012
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
The human somatostatin receptor type 2 as an imaging and suicide reporter gene for pluripotent stem cell-derived therapy of myocardial infarction
Katrien Neyrinck, Natacha Breuls, Bryan Holvoet, Wouter Oosterlinck, Esther Wolfs, Hubert Vanbilloen, Olivier Gheysens, Robin Duelen, Willy Gsell, Ivo Lambrichts, Uwe Himmelreich, Catherine M. Verfaillie, Maurilio Sampaolesi, Christophe M. Deroose
Theranostics 2018; 8(10): 2799-2813. doi:10.7150/thno.22980
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Plectin-targeted liposomes enhance the therapeutic efficacy of a PARP inhibitor in the treatment of ovarian cancer
Siva Sai Krishna Dasa, Galina Diakova, Ryo Suzuki, Anne M. Mills, Michael F. Gutknecht, Alexander L. Klibanov, Jill K. Slack-Davis, Kimberly A. Kelly
Theranostics 2018; 8(10): 2782-2798. doi:10.7150/thno.23050
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Placenta-specific drug delivery by trophoblast-targeted nanoparticles in mice
Baozhen Zhang, Lunbo Tan, Yan Yu, Baobei Wang, Zhilong Chen, Jinyu Han, Mengxia Li, Jie Chen, Tianxia Xiao, Balamurali K Ambati, Lintao Cai, Qing Yang, Nihar R Nayak, Jian Zhang, Xiujun Fan
Theranostics 2018; 8(10): 2765-2781. doi:10.7150/thno.22904
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Polypyrrole-chitosan conductive biomaterial synchronizes cardiomyocyte contraction and improves myocardial electrical impulse propagation
Zhi Cui, Nathan C. Ni, Jun Wu, Guo-Qing Du, Sheng He, Terrence M. Yau, Richard D. Weisel, Hsing-Wen Sung, Ren-Ke Li
Theranostics 2018; 8(10): 2752-2764. doi:10.7150/thno.22599
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

new Nanotheranostics in PubMed Central

Theme Issue on “Brain Theranostics. Guest Editor: Prof. Rachela Popovtzer, PhD
Cover image
Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues