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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
Evaluation of a Novel Thermal Accelerant for Augmentation of Microwave Energy during Image-guided Tumor Ablation
William Keun Chan Park, Aaron Wilhelm Palmer Maxwell, Victoria Elizabeth Frank, Michael Patrick Primmer, Scott Andrew Collins, Grayson Luderman Baird, Damian Edward Dupuy
Theranostics 2017; 7(4): 1026-1035. doi:10.7150/thno.18191
[Abstract] [Full text] [PDF]


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Review
Theranostic DNAzymes
Wenhu Zhou, Jinsong Ding, Juewen Liu
Theranostics 2017; 7(4): 1010-1025. doi:10.7150/thno.17736
[Abstract] [Full text] [PDF]


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Research Paper
HDAC6 regulates IL-17 expression in T lymphocytes: implications for HDAC6-targeted therapies
Bing Yan, Yang Liu, Hong Bai, Miao Chen, Songbo Xie, Dengwen Li, Min Liu, Jun Zhou
Theranostics 2017; 7(4): 1002-1009. doi:10.7150/thno.17615
[Abstract] [Full text] [PDF]


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Research Paper
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer
Wei-Jun Wei, Zhen-Kui Sun, Chen-Tian Shen, Hong-Jun Song, Xin-Yun Zhang, Zhong-Ling Qiu, Quan-Yong Luo
Theranostics 2017; 7(4): 987-1001. doi:10.7150/thno.17322
[Abstract] [Full text] [PDF]


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Research Paper
Integration of Receptor Tyrosine Kinases Determines Sensitivity to PI3Kα-selective Inhibitors in Breast Cancer
Yi-chao Xu, Xiang Wang, Yi Chen, Si-meng Chen, Xin-ying Yang, Yi-ming Sun, Mei-yu Geng, Jian Ding, Ling-hua Meng
Theranostics 2017; 7(4): 974-986. doi:10.7150/thno.17830
[Abstract] [Full text] [PDF]


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Research Paper
Development of Sialic Acid-coated Nanoparticles for Targeting Cancer and Efficient Evasion of the Immune System
Young-Hwa Kim, Kyung Hyun Min, Zhantong Wang, Jihoon Kim, Orit Jacobson, Peng Huang, Guizhi Zhu, Yijing Liu, Bryant Yung, Gang Niu, Xiaoyuan Chen
Theranostics 2017; 7(4): 962-973. doi:10.7150/thno.19061
[Abstract] [Full text] [PDF]


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Research Paper
Antigen-responsive molecular sensor enables real-time tumor-specific imaging
Hyunjin Kim, Hak Soo Choi, Seok-Ki Kim, Byung Il Lee, Yongdoo Choi
Theranostics 2017; 7(4): 952-961. doi:10.7150/thno.16647
[Abstract] [Full text] [PDF]


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Research Paper
Association of γH2AX at Diagnosis with Chemotherapy Outcome in Patients with Breast Cancer
Sherry X. Yang, Eric C. Polley, Dat Nguyen
Theranostics 2017; 7(4): 945-951. doi:10.7150/thno.19102
[Abstract] [Full text] [PDF]


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Research Paper
An Electrochemical Strategy using Multifunctional Nanoconjugates for Efficient Simultaneous Detection of Escherichia coli O157: H7 and Vibrio cholerae O1
Yan Li, Ya Xiong, Lichao Fang, Lili Jiang, Hui Huang, Jun Deng, Wenbin Liang, Junsong Zheng
Theranostics 2017; 7(4): 935-944. doi:10.7150/thno.17544
[Abstract] [Full text] [PDF]


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Research Paper
Visualization of Macrophage Recruitment to Inflammation Lesions using Highly Sensitive and Stable Radionuclide-Embedded Gold Nanoparticles as a Nuclear Bio-Imaging Platform
Sang Bong Lee, Ho Won Lee, Thoudam Debraj Singh, Yinghua Li, Sang Kyoon Kim, Sung Jin Cho, Sang-Woo Lee, Shin Young Jeong, Byeong-Cheol Ahn, Sangil Choi, In-Kyu Lee, Dong-Kwon Lim, Jaetae Lee, Yong Hyun Jeon
Theranostics 2017; 7(4): 926-934. doi:10.7150/thno.17131
[Abstract] [Full text] [PDF]


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Research Paper
Visualization of a neurotropic flavivirus infection in mouse reveals unique viscerotropism controlled by host type I interferon signaling
Xiao-Feng Li, Xiao-Dan Li, Cheng-Lin Deng, Hao-Long Dong, Qiu-Yan Zhang, Qing Ye, Han-Qing Ye, Xing-Yao Huang, Yong-Qiang Deng, Bo Zhang, Cheng-Feng Qin
Theranostics 2017; 7(4): 912-925. doi:10.7150/thno.16615
[Abstract] [Full text] [PDF]


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Research Paper
Incorporating gold nanoclusters and target-directed liposomes as a synergistic amplified colorimetric sensor for HER2-positive breast cancer cell detection
Yu Tao, Mingqiang Li, Bumjun Kim, Debra T. Auguste
Theranostics 2017; 7(4): 899-911. doi:10.7150/thno.17927
[Abstract] [Full text] [PDF]


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Research Paper
Edaravone-Encapsulated Agonistic Micelles Rescue Ischemic Brain Tissue by Tuning Blood-Brain Barrier Permeability
Qu Jin, Yu Cai, Sihan Li, Haoran Liu, Xingyu Zhou, Chunqiang Lu, Xihui Gao, Jun Qian, Jun Zhang, Shenghong Ju, Cong Li
Theranostics 2017; 7(4): 884-898. doi:10.7150/thno.18219
[Abstract] [Full text] [PDF]


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Research Paper
Sensitive detection of protein biomarkers using silver nanoparticles enhanced immunofluorescence assay
Li-Jun Zhao, Ru-Jia Yu, Wei Ma, Huan-Xing Han, He Tian, Ruo-Can Qian, Yi-Tao Long
Theranostics 2017; 7(4): 876-883. doi:10.7150/thno.17575
[Abstract] [Full text] [PDF]


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Research Paper
A Crucial Role of CXCL14 for Promoting Regulatory T Cells Activation in Stroke
Hsu-Tung Lee, Shih-Ping Liu, Chen-Huan Lin, Sophie Wei Lee, Chung Y. Hsu, Huey-Kang Sytwu, Chia-Hung Hsieh, Woei-Cherng Shyu
Theranostics 2017; 7(4): 855-875. doi:10.7150/thno.17558
[Abstract] [Full text] [PDF]


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Research Paper
Phase-transitional Fe3O4/perfluorohexane Microspheres for Magnetic Droplet Vaporization
Ronghui Wang, Yang Zhou, Ping Zhang, Yu Chen, Wei Gao, Jinshun Xu, Hangrong Chen, Xiaojun Cai, Kun Zhang, Pan Li, Zhigang Wang, Bing Hu, Tao Ying, Yuanyi Zheng
Theranostics 2017; 7(4): 846-854. doi:10.7150/thno.17251
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 8.854, according to 2016 release of Journal Citation Reports®. Congratulations!

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Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...
Theme Issue on “Brain Theranostics. Guest Editor: Prof. Rachela Popovtzer, PhD
Theme Issue on “Stem Cell Theranostics. Guest Editors: Kristopher Kilian, PhD, and Deok-Ho Kim, PhD
Theme Issue on “Biomolecular and biomimetic materials for theranostics. Guest Editors: Haiyun Song, PhD, and Chunhai Fan, PhD
Theme Issue on “Translational theranostics for infectious diseases. Guest Editor: Dr. Tony Y. Hu, Houston Methodist Research Institute
Theme Issue on “Light-Mediated Deep-Tissue Theranostics. Guest Editors: Dr. Gang Han, University of Massachusetts Medical School, and Dr. Jin Xie, University of Georgia
new Congratulations to Dr. Chen for receiving the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.
NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues