Cover image

Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


toc.jpg

Research Paper
Pharmacokinetics and biodistribution of polymeric micelles containing miRNA and small-molecule drug in orthotopic pancreatic tumor-bearing mice
Virender Kumar, Vaibhav Mundra, Yang Peng, Yingzhe Wang, Chalet Tan, Ram I. Mahato
Theranostics 2018; 8(15): 4033-4049. doi:10.7150/thno.24945
[Abstract] [Full text] [PDF]


toc.jpg

Review
Aptamers in the Therapeutics and Diagnostics Pipelines
Harleen Kaur, John G. Bruno, Amit Kumar, Tarun Kumar Sharma
Theranostics 2018; 8(15): 4016-4032. doi:10.7150/thno.25958
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
circEPSTI1 as a Prognostic Marker and Mediator of Triple-Negative Breast Cancer Progression
Bo Chen, Weidong Wei, Xiaojia Huang, Xinhua Xie, Yanan Kong, Danian Dai, Lu Yang, Jin Wang, Hailin Tang, Xiaoming Xie
Theranostics 2018; 8(14): 4003-4015. doi:10.7150/thno.24106
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
[18F]fluoroethyltyrosine-induced Cerenkov Luminescence Improves Image-Guided Surgical Resection of Glioma
David Y. Lewis, Richard Mair, Alan Wright, Kieren Allinson, Scott K. Lyons, Tom Booth, Julia Jones, Robert Bielik, Dmitry Soloviev, Kevin M. Brindle
Theranostics 2018; 8(14): 3991-4002. doi:10.7150/thno.23709
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
The S100A4 Protein Signals through the ErbB4 Receptor to Promote Neuronal Survival
Stanislava Pankratova, Jorg Klingelhofer, Oksana Dmytriyeva, Sylwia Owczarek, Alexander Renziehausen, Nelofer Syed, Alexandra E. Porter, David T. Dexter, Darya Kiryushko
Theranostics 2018; 8(14): 3977-3990. doi:10.7150/thno.22274
[Abstract] [Full text] [PDF]


Editorial
Microvesicles and ectosomes in angiogenesis and diabetes - message in a bottle in the vascular ocean
Michael Lichtenauer, Christian Jung
Theranostics 2018; 8(14): 3974-3976. doi:10.7150/thno.27154
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Development of an in vitro cell-sheet cancer model for chemotherapeutic screening
Jaewang Lee, Daiha Shin, Jong-Lyel Roh
Theranostics 2018; 8(14): 3964-3973. doi:10.7150/thno.26439
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Polylactide-tethered prodrugs in polymeric nanoparticles as reliable nanomedicines for the efficient eradication of patient-derived hepatocellular carcinoma
Hangxiang Wang, Liqian Zhou, Ke Xie, Jiaping Wu, Penghong Song, Haiyang Xie, Lin Zhou, Jialin Liu, Xiao Xu, Youqing Shen, Shusen Zheng
Theranostics 2018; 8(14): 3949-3963. doi:10.7150/thno.26161
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19
Jing Ren, Liang Ding, Dongya Zhang, Guoping Shi, Qianyun Xu, Sunan Shen, Yaping Wang, Tingting Wang, Yayi Hou
Theranostics 2018; 8(14): 3932-3948. doi:10.7150/thno.25541
[Abstract] [Full text] [PDF]


toc.jpg

Review
[18F]Tetrafluoroborate ([18F]TFB) and its analogs for PET imaging of the sodium/iodide symporter
Huailei Jiang, Timothy R. DeGrado
Theranostics 2018; 8(14): 3918-3931. doi:10.7150/thno.24997
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Profiling the circulating miRnome reveals a temporal regulation of the bone injury response
Andreia M. Silva, Maria I. Almeida, José H. Teixeira, Cristina Ivan, Joana Oliveira, Daniel Vasconcelos, Nuno Neves, Cláudia Ribeiro-Machado, Carla Cunha, Mário A. Barbosa, George A. Calin, Susana G. Santos
Theranostics 2018; 8(14): 3902-3917. doi:10.7150/thno.24444
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Tumor-suppressing miR-141 gene complex-loaded tissue-adhesive glue for the locoregional treatment of hepatocellular carcinoma
Min-Kyoung Kim, Young-Ah Moon, Chung Kil Song, Rengarajan Baskaran, Sijeong Bae, Su-Geun Yang
Theranostics 2018; 8(14): 3891-3901. doi:10.7150/thno.24056
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Circulating ectosomes: Determination of angiogenic microRNAs in type 2 diabetes
Ewa Ł. Stępień, Martyna Durak-Kozica, Agnieszka Kamińska, Marta Targosz-Korecka, Marcin Libera, Grzegorz Tylko, Agnieszka Opalińska, Maria Kapusta, Bogdan Solnica, Adriana Georgescu, Marina C. Costa, Agnieszka Czyżewska-Buczyńska, Wojciech Witkiewicz, Maciej T. Małecki, Francisco J. Enguita
Theranostics 2018; 8(14): 3874-3890. doi:10.7150/thno.23334
[Abstract] [Full text] [PDF]


Editorial
Drug nanorods are potential new nanocarriers for intracellular protein delivery
Weiping Gao, Mengmeng Sun
Theranostics 2018; 8(14): 3872-3873. doi:10.7150/thno.27815
[Abstract] [Full text] [PDF]


Editorial
Oxygenating the way for enhanced chemophototherapy
Wen Jiang, Ian Michael Delahunty, Jin Xie
Theranostics 2018; 8(14): 3870-3871. doi:10.7150/thno.27810
[Abstract] [Full text] [PDF]


toc.jpg

Research Paper
Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors
Diego Sanchez-Martinez, Nerea Allende-Vega, Stefania Orecchioni, Giovanna Talarico, Amelie Cornillon, Dang-Nghiem Vo, Celine Rene, Zhao-Yang Lu, Ewelina Krzywinska, Alberto Anel, Eva M. Galvez, Julian Pardo, Bruno Robert, Pierre Martineau, Yosr Hicheri, Francesco Bertolini, Guillaume Cartron, Martin Villalba
Theranostics 2018; 8(14): 3856-3869. doi:10.7150/thno.25149
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

Nanotheranostics in PubMed Central

Cover image
Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues