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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors
Diego Sanchez-Martinez, Nerea Allende-Vega, Stefania Orecchioni, Giovanna Talarico, Amelie Cornillon, Dang-Nghiem Vo, Celine Rene, Zhao-Yang Lu, Ewelina Krzywinska, Alberto Anel, Eva M. Galvez, Julian Pardo, Bruno Robert, Pierre Martineau, Yosr Hicheri, Francesco Bertolini, Guillaume Cartron, Martin Villalba
Theranostics 2018; 8(14): 3856-3869. doi:10.7150/thno.25149
[Abstract] [Full text] [PDF]


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Research Paper
HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling
Yu-Syuan Chen, Ching-Wen Chang, Yeou-Guang Tsay, Liu-Ying Huang, Yi-Chen Wu, Li-Hao Cheng, Cheng-Chieh Yang, Cheng-Hsien Wu, Wan-Huai Teo, Kai-Feng Hung, Chih-Yang Huang, Te-Chang Lee, Jeng-Fan Lo
Theranostics 2018; 8(14): 3841-3855. doi:10.7150/thno.25784
[Abstract] [Full text] [PDF]


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Research Paper
Targeting S1PR1/STAT3 loop abrogates desmoplasia and chemosensitizes pancreatic cancer to gemcitabine
Manendra Babu Lankadasari, Jayasekharan S. Aparna, Sabira Mohammed, Shirley James, Kazunori Aoki, Valsalakumari S. Binu, Sindhu Nair, Kuzhuvelil B. Harikumar
Theranostics 2018; 8(14): 3824-3840. doi:10.7150/thno.25308
[Abstract] [Full text] [PDF]


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Research Paper
Self-assembled dual fluorescence nanoparticles for CD44-targeted delivery of anti-miR-27a in liver cancer theranostics
Xiao Zheng, Fan Zhang, Yawei Zhao, Jing Zhang, Jianati Dawulieti, Yue Pan, Lianzhi Cui, Madi Sun, Dan Shao, Mingqiang Li, Kan He, Ming Zhang, Jing Li, Li Chen
Theranostics 2018; 8(14): 3808-3823. doi:10.7150/thno.25255
[Abstract] [Full text] [PDF]


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Research Paper
Development of Paper-Based Analytical Devices for Minimizing the Viscosity Effect in Human Saliva
Julaluk Noiphung, Michael P. Nguyen, Chamindie Punyadeera, Yunxia Wan, Wanida Laiwattanapaisal, Charles S. Henry
Theranostics 2018; 8(14): 3797-3807. doi:10.7150/thno.24941
[Abstract] [Full text] [PDF]


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Research Paper
Nano-delivery of fraxinellone remodels tumor microenvironment and facilitates therapeutic vaccination in desmoplastic melanoma
Lin Hou, Qi Liu, Limei Shen, Yun Liu, Xueqiong Zhang, Fengqian Chen, Leaf Huang
Theranostics 2018; 8(14): 3781-3796. doi:10.7150/thno.24821
[Abstract] [Full text] [PDF]


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Research Paper
Molecular signatures of liver dysfunction are distinct in fungal and bacterial infections in mice
Barbara Schaarschmidt, Sebastian Vlaic, Anna Medyukhina, Sophie Neugebauer, Sandor Nietzsche, Falk A. Gonnert, Jürgen Rödel, Mervyn Singer, Michael Kiehntopf, Marc Thilo Figge, Ilse D. Jacobsen, Michael Bauer, Adrian T. Press
Theranostics 2018; 8(14): 3766-3780. doi:10.7150/thno.24333
[Abstract] [Full text] [PDF]


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Research Paper
Identification and Functional Characterization of Long Non-coding RNA MIR22HG as a Tumor Suppressor for Hepatocellular Carcinoma
Dong-Yan Zhang, Xue-Jing Zou, Chuan-Hui Cao, Ting Zhang, Ling Lei, Xiao-Long Qi, Li Liu, De-Hua Wu
Theranostics 2018; 8(14): 3751-3765. doi:10.7150/thno.22493
[Abstract] [Full text] [PDF]


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Research Paper
Blocking CDK1/PDK1/β-Catenin signaling by CDK1 inhibitor RO3306 increased the efficacy of sorafenib treatment by targeting cancer stem cells in a preclinical model of hepatocellular carcinoma
Chuan Xing Wu, Xiao Qi Wang, Siu Ho Chok, Kwan Man, Simon Hing Yin Tsang, Albert Chi Yan Chan, Ka Wing Ma, Wei Xia, Tan To Cheung
Theranostics 2018; 8(14): 3737-3750. doi:10.7150/thno.25487
[Abstract] [Full text] [PDF]


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Research Paper
Suspension state promotes metastasis of breast cancer cells by up-regulating cyclooxygenase-2
Xiaomei Zhang, Li Yang, Shu Chien, Yonggang Lv
Theranostics 2018; 8(14): 3722-3736. doi:10.7150/thno.25434
[Abstract] [Full text] [PDF]


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Research Paper
AP-2β inhibits hepatocellular carcinoma invasion and metastasis through Slug and Snail to suppress epithelial-mesenchymal transition
Liu Yang, Junlu Qiu, Yuzhong Xiao, Xiang Hu, Qing Liu, Li Chen, Wenhuan Huang, Xinxin Li, Limin Li, Jian Zhang, Xiaofeng Ding, Shuanglin Xiang
Theranostics 2018; 8(13): 3707-3721. doi:10.7150/thno.25166
[Abstract] [Full text] [PDF]


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Research Paper
Precise theranostic nanomedicines for inhibiting vulnerable atherosclerotic plaque progression through regulation of vascular smooth muscle cell phenotype switching
Sai Ma, Seyed Mohammad Motevalli, Jiangwei Chen, Meng-Qi Xu, Yabin Wang, Jing Feng, Ya Qiu, Dong Han, Miaomiao Fan, Meiling Ding, Li Fan, Weisheng Guo, Xing-Jie Liang, Feng Cao
Theranostics 2018; 8(13): 3693-3706. doi:10.7150/thno.24364
[Abstract] [Full text] [PDF]


Editorial
Take a Deep Breath - Monitoring of Inhaled Nanoparticles with Magnetic Particle Imaging
Franz Wegner, Thorsten M. Buzug, Joerg Barkhausen
Theranostics 2018; 8(13): 3691-3692. doi:10.7150/thno.27454
[Abstract] [Full text] [PDF]


Editorial
Punching and Electroporation for Enhanced Transdermal Drug Delivery
Guang Yang, Yuqi Zhang, Zhen Gu
Theranostics 2018; 8(13): 3688-3690. doi:10.7150/thno.27236
[Abstract] [Full text] [PDF]


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Research Paper
In vivo tracking and quantification of inhaled aerosol using magnetic particle imaging towards inhaled therapeutic monitoring
Zhi Wei Tay, Prashant Chandrasekharan, Xinyi Yedda Zhou, Elaine Yu, Bo Zheng, Steven Conolly
Theranostics 2018; 8(13): 3676-3687. doi:10.7150/thno.26608
[Abstract] [Full text] [PDF]


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Review
Angio-LncRs: LncRNAs that regulate angiogenesis and vascular disease
Bo Yu, Shusheng Wang
Theranostics 2018; 8(13): 3654-3675. doi:10.7150/thno.26024
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

Nanotheranostics in PubMed Central

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Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues