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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Latest articles:


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Research Paper
Photo-decomposable Organic Nanoparticles for Combined Tumor Optical Imaging and Multiple Phototherapies
Wenjun Miao, Hyungjun Kim, Vipul Gujrati, Jin Yong Kim, Hyeongsu Jon, Yonghyun Lee, Minsuk Choi, Jinjoo Kim, Soyoung Lee, Dong Yun Lee, Sukmo Kang, Sangyong Jon
Theranostics 2016; 6(13): 2367-2379. doi:10.7150/thno.15829
[Abstract] [Full text] [PDF]


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Research Paper
ROS-Responsive Mitochondria-Targeting Blended Nanoparticles: Chemo- and Photodynamic Synergistic Therapy for Lung Cancer with On-Demand Drug Release upon Irradiation with a Single Light Source
Caixia Yue, Yuming Yang, Chunlei Zhang, Gabriel Alfranca, Shangli Cheng, Lijun Ma, Yanlei Liu, Xiao Zhi, Jian Ni, Weihua Jiang, Jie Song, Jesús M. de la Fuente, Daxiang Cui
Theranostics 2016; 6(13): 2352-2366. doi:10.7150/thno.15433
[Abstract] [Full text] [PDF]


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Research Paper
NIR-Laser-Controlled Drug Release from DOX/IR-780-Loaded Temperature-Sensitive-Liposomes for Chemo-Photothermal Synergistic Tumor Therapy
Fei Yan, Wanlu Duan, Yekuo Li, Hao Wu, Yuli Zhou, Min Pan, Hongmei Liu, Xin Liu, Hairong Zheng
Theranostics 2016; 6(13): 2337-2351. doi:10.7150/thno.14937
[Abstract] [Full text] [PDF]


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Research Paper
Sphingomyelin Liposomes Containing Porphyrin-phospholipid for Irinotecan Chemophototherapy
Kevin A Carter, Dandan Luo, Aida Razi, Jumin Geng, Shuai Shao, Joaquin Ortega, Jonathan F Lovell
Theranostics 2016; 6(13): 2329-2336. doi:10.7150/thno.15701
[Abstract] [Full text] [PDF]


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Research Paper
Near Infrared Fluorescent Nanoparticles Derived from Hyaluronic Acid Improve Tumor Contrast for Image-Guided Surgery
Tanner K. Hill, Sneha S. Kelkar, Nicholas E. Wojtynek, Joshua J. Souchek, William M. Payne, Kristina Stumpf, Frank C. Marini, Aaron M. Mohs
Theranostics 2016; 6(13): 2314-2328. doi:10.7150/thno.16514
[Abstract] [Full text] [PDF]


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Research Paper
Core-Shell Nanostars for Multimodal Therapy and Imaging
Mengyuan Li, Lele Li, Changyou Zhan, Daniel S. Kohane
Theranostics 2016; 6(13): 2306-2313. doi:10.7150/thno.15843
[Abstract] [Full text] [PDF]


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Research Paper
X-Ray Induced Photodynamic Therapy: A Combination of Radiotherapy and Photodynamic Therapy
Geoffrey D. Wang, Ha T. Nguyen, Hongmin Chen, Phillip B. Cox, Lianchun Wang, Koichi Nagata, Zhonglin Hao, Andrew Wang, Zibo Li, Jin Xie
Theranostics 2016; 6(13): 2295-2305. doi:10.7150/thno.16141
[Abstract] [Full text] [PDF]


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Research Paper
Highly Effective Auger-Electron Therapy in an Orthotopic Glioblastoma Xenograft Model using Convection-Enhanced Delivery
Helge Thisgaard, Bo Halle, Charlotte Aaberg-Jessen, Birgitte Brinkmann Olsen, Anne Sofie Nautrup Therkelsen, Johan Hygum Dam, Niels Langkjær, Sune Munthe, Kjell Någren, Poul Flemming Høilund-Carlsen, Bjarne Winther Kristensen
Theranostics 2016; 6(12): 2278-2291. doi:10.7150/thno.15898
[Abstract] [Full text] [PDF]


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Research Paper
A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer
Pierre Adumeau, Kathryn E. Carnazza, Christian Brand, Sean D. Carlin, Thomas Reiner, Brian J. Agnew, Jason S. Lewis, Brian M. Zeglis
Theranostics 2016; 6(12): 2267-2277. doi:10.7150/thno.16744
[Abstract] [Full text] [PDF]


Research Paper
Combination Therapy for Ulcerative Colitis: Orally Targeted Nanoparticles Prevent Mucosal Damage and Relieve Inflammation
Bo Xiao, Zhan Zhang, Emilie Viennois, Yuejun Kang, Mingzhen Zhang, Moon Kwon Han, Jiucun Chen, Didier Merlin
Theranostics 2016; 6(12): 2250-2266. doi:10.7150/thno.15710
[Abstract] [Full text] [PDF]


Research Paper
Multivalent Targeting Based Delivery of Therapeutic Peptide using AP1-ELP Carrier for Effective Cancer Therapy
Vijaya Sarangthem, Yunjae Kim, Thoudam Debraj Singh, Bo-Yeon Seo, Sun-Ha Cheon, Young-Jin Lee, Byung-Heon Lee, Rang-Woon Park
Theranostics 2016; 6(12): 2235-2249. doi:10.7150/thno.16425
[Abstract] [Full text] [PDF]


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Research Paper
In Vitro and In Vivo Evaluation of 89Zr-DS-8273a as a Theranostic for Anti-Death Receptor 5 Therapy
Ingrid J.G. Burvenich, Fook-Thean Lee, Nancy Guo, Hui K. Gan, Angela Rigopoulos, Adam C. Parslow, Graeme J. O'Keefe, Sylvia J. Gong, Henri Tochon-Danguy, Stacey E. Rudd, Paul S. Donnelly, Masakatsu Kotsuma, Toshiaki Ohtsuka, Giorgio Senaldi, Andrew M. Scott
Theranostics 2016; 6(12): 2225-2234. doi:10.7150/thno.16260
[Abstract] [Full text] [PDF]


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Research Paper
Lycorine Downregulates HMGB1 to Inhibit Autophagy and Enhances Bortezomib Activity in Multiple Myeloma
Mridul Roy, Long Liang, Xiaojuan Xiao, Yuanliang Peng, Yuhao Luo, Weihua Zhou, Ji Zhang, Lugui Qiu, Shuaishuai Zhang, Feng Liu, Mao Ye, Wen Zhou, Jing Liu
Theranostics 2016; 6(12): 2209-2224. doi:10.7150/thno.15584
[Abstract] [Full text] [PDF]


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Research Paper
Biodegradable Nitrogen-Doped Carbon Nanodots for Non-Invasive Photoacoustic Imaging and Photothermal Therapy
Changho Lee, Woosung Kwon, Songeun Beack, Donghyun Lee, Yoonsang Park, Hyemin Kim, Sei Kwang Hahn, Shi-Woo Rhee, Chulhong Kim
Theranostics 2016; 6(12): 2196-2208. doi:10.7150/thno.16923
[Abstract] [Full text] [PDF]


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Research Paper
Deficiency of ATP6V1H Causes Bone Loss by Inhibiting Bone Resorption and Bone Formation through the TGF-β1 Pathway
Xiaohong Duan, Jin Liu, Xueni Zheng, Zhe Wang, Yanli Zhang, Ying Hao, Tielin Yang, Hongwen Deng
Theranostics 2016; 6(12): 2183-2195. doi:10.7150/thno.17140
[Abstract] [Full text] [PDF]


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Research Paper
Versatile pH-response Micelles with High Cell-Penetrating Helical Diblock Copolymers for Photoacoustic Imaging Guided Synergistic Chemo-Photothermal Therapy
Shengyu Shi, Yajing Liu, Yu Chen, Zhihuang Zhang, Yunsheng Ding, Zongquan Wu, Jun Yin, Liming Nie
Theranostics 2016; 6(12): 2170-2182. doi:10.7150/thno.16633
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 8.854, according to 2016 release of Journal Citation Reports®. Congratulations!

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Most Cited Paper Award for year 2015: Winners of this year are Chao Wang, Liang Cheng, Zhuang Liu, for the paper "Upconversion Nanoparticles for Photodynamic Therapy and Other Cancer Therapeutics". Details ...
Theme Issue on “Stem Cell Theranostics. Guest Editors: Kristopher Kilian, PhD, and Deok-Ho Kim, PhD
Theme Issue on “Biomolecular and biomimetic materials for theranostics. Guest Editors: Haiyun Song, PhD, and Chunhai Fan, PhD
Theme Issue on “Translational theranostics for infectious diseases. Guest Editor: Dr. Tony Y. Hu, Houston Methodist Research Institute
Theme Issue on “Light-Mediated Deep-Tissue Theranostics. Guest Editors: Dr. Gang Han, University of Massachusetts Medical School, and Dr. Jin Xie, University of Georgia
new Congratulations to Dr. Chen for receiving the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.
NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues