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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
Injectable OPF/graphene oxide hydrogels provide mechanical support and enhance cell electrical signaling after implantation into myocardial infarct
Jin Zhou, Xiaoning Yang, Wei Liu, Chunlan Wang, Yuan Shen, Fengzhi Zhang, Huimin Zhu, Hongji Sun, Jiayun Chen, Johnny Lam, Antonios G. Mikos, Changyong Wang
Theranostics 2018; 8(12): 3317-3330. doi:10.7150/thno.25504
[Abstract] [Full text] [PDF]


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Research Paper
Response to Single Low-dose 177Lu-DOTA-EB-TATE Treatment in Patients with Advanced Neuroendocrine Neoplasm: A Prospective Pilot Study
Hao Wang, Yuejuan Cheng, Jingjing Zhang, Jie Zang, Hui Li, Qingxing Liu, Jingnan Wang, Orit Jacobson, Fang Li, Zhaohui Zhu, Xiaoyuan Chen
Theranostics 2018; 8(12): 3308-3316. doi:10.7150/thno.25919
[Abstract] [Full text] [PDF]


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Review
Shape-, size- and structure-controlled synthesis and biocompatibility of iron oxide nanoparticles for magnetic theranostics
Wensheng Xie, Zhenhu Guo, Fei Gao, Qin Gao, Dan Wang, Bor-shuang Liaw, Qiang Cai, Xiaodan Sun, Xiumei Wang, Lingyun Zhao
Theranostics 2018; 8(12): 3284-3307. doi:10.7150/thno.25220
[Abstract] [Full text] [PDF]


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Research Paper
Colorimetric in situ assay of membrane-bound enzyme based on lipid bilayer inhibition of ion transport
Juan Zhang, Defeng Li, Xiquan Yue, Meiling Zhang, Ping Liu, Genxi Li
Theranostics 2018; 8(12): 3275-3283. doi:10.7150/thno.25123
[Abstract] [Full text] [PDF]


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Research Paper
Glypican-3-targeted precision diagnosis of hepatocellular carcinoma on clinical sections with a supramolecular 2D imaging probe
Hai-Hao Han, Yu-Jiao Qiu, Yuan-Yuan Shi, Wen Wen, Xiao-Peng He, Li-Wei Dong, Ye-Xiong Tan, Yi-Tao Long, He Tian, Hong-Yang Wang
Theranostics 2018; 8(12): 3268-3274. doi:10.7150/thno.24711
[Abstract] [Full text] [PDF]


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Research Paper
A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma
Jingya Sun, Xin Wang, Boyun Tang, Hongchun Liu, Minmin Zhang, Yueqin Wang, Fangfang Ping, Jian Ding, Aijun Shen, Meiyu Geng
Theranostics 2018; 8(12): 3256-3267. doi:10.7150/thno.23964
[Abstract] [Full text] [PDF]


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Research Paper
Rich club disturbances of the human connectome from subjective cognitive decline to Alzheimer's disease
Tianyi Yan, Wenhui Wang, Liu Yang, Kewei Chen, Rong Chen, Ying Han
Theranostics 2018; 8(12): 3237-3255. doi:10.7150/thno.23772
[Abstract] [Full text] [PDF]


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Research Paper
Oncogenic TRIM31 confers gemcitabine resistance in pancreatic cancer via activating the NF-κB signaling pathway
Chao Yu, Shiyu Chen, Yuntao Guo, Chengyi Sun
Theranostics 2018; 8(12): 3224-3236. doi:10.7150/thno.23259
[Abstract] [Full text] [PDF]


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Research Paper
Serum amyloid P component therapeutically attenuates atherosclerosis in mice via its effects on macrophages
Dan Xi, Jinzhen Zhao, Kai Guo, Lu Hu, Hui Chen, Weijun Fu, Wenyan Lai, Zhigang Guo
Theranostics 2018; 8(12): 3214-3223. doi:10.7150/thno.22704
[Abstract] [Full text] [PDF]


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Research Paper
DNA damage predicts prognosis and treatment response in colorectal liver metastases superior to immunogenic cell death and T cells
Johannes Laengle, Judith Stift, Agnes Bilecz, Brigitte Wolf, Andrea Beer, Balazs Hegedus, Stefan Stremitzer, Patrick Starlinger, Dietmar Tamandl, Dietmar Pils, Michael Bergmann
Theranostics 2018; 8(12): 3198-3213. doi:10.7150/thno.24699
[Abstract] [Full text] [PDF]


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Research Paper
A hook effect-free immunochromatographic assay (HEF-ICA) for measuring the C-reactive protein concentration in one drop of human serum
Jusung Oh, Hyou-Arm Joung, Hyung Soo Han, Jong Kun Kim, Min-Gon Kim
Theranostics 2018; 8(12): 3189-3197. doi:10.7150/thno.24034
[Abstract] [Full text] [PDF]


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Research Paper
The HER2 inhibitor lapatinib potentiates doxorubicin-induced cardiotoxicity through iNOS signaling
Wan-Tseng Hsu, Ching-Ying Huang, Christopher Y.T. Yen, Ann-Lii Cheng, Patrick C.H. Hsieh
Theranostics 2018; 8(12): 3176-3188. doi:10.7150/thno.23207
[Abstract] [Full text] [PDF]


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Research Paper
Pre-existing anti-polyethylene glycol antibody reduces the therapeutic efficacy and pharmacokinetics of PEGylated liposomes
Yuan-Chin Hsieh, Hsin-Ell Wang, Wen-Wei Lin, Steve R. Roffler, Ta-Chun Cheng, Yu-Cheng Su, Jia-Je Li, Chao-Cheng Chen, Chun-Han Huang, Bing-Mae Chen, Jaw-Yuan Wang, Tian-Lu Cheng, Fang-Ming Chen
Theranostics 2018; 8(11): 3164-3175. doi:10.7150/thno.22164
[Abstract] [Full text] [PDF]


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Research Paper
A smart bilayered scaffold supporting keratinocytes and muscle cells in micro/nano-scale for urethral reconstruction
XiangGuo Lv, Chao Feng, YiDong Liu, XuFeng Peng, ShiYan Chen, DongDong Xiao, HuaPing Wang, Zhe Li, YueMin Xu, MuJun Lu
Theranostics 2018; 8(11): 3153-3163. doi:10.7150/thno.22080
[Abstract] [Full text] [PDF]


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Research Paper
Negative regulation of cationic nanoparticle-induced inflammatory toxicity through the increased production of prostaglandin E2 via mitochondrial DNA-activated Ly6C+ monocytes
Li Liu, Yantong Liu, Bocheng Xu, Chuyu Liu, Yanpeng Jia, Ting Liu, Chunju Fang, Wei Wang, Jun Ren, Zhiyao He, Ke Men, Xiao Liang, Min Luo, Bin Shao, Ye Mao, Henyi Xiao, Zhiyong Qian, Jia Geng, Birong Dong, Peng Mi, Yu Jiang, Yuquan Wei, Xiawei Wei
Theranostics 2018; 8(11): 3138-3152. doi:10.7150/thno.21693
[Abstract] [Full text] [PDF]


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Research Paper
Image-guided chemotherapy with specifically tuned blood brain barrier permeability in glioma margins
Xihui Gao, Qi Yue, Yikang Liu, Dandan Fan, Kun Fan, Sihan Li, Jun Qian, Limei Han, Fang Fang, Fulin Xu, Daoying Geng, Liang Chen, Xin Zhou, Ying Mao, Cong Li
Theranostics 2018; 8(11): 3126-3137. doi:10.7150/thno.24784
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

new Nanotheranostics in PubMed Central

Theme Issue on “Brain Theranostics. Guest Editor: Prof. Rachela Popovtzer, PhD
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Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues