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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


Editorial
Resistant to Targeted Therapy - Aim for Metabolic Liabilities
André Lima Queiroz, Helin Vakifahmetoglu-Norberg, Erik Norberg
Theranostics 2018; 8(7): 2061-2063. doi:10.7150/thno.24454
[Abstract] [Full text] [PDF]


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Research Paper
3′-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells
Yan Sun, Yong-Hao Huang, Feng-Ying Huang, Wen-Li Mei, Quan Liu, Cai-Chun Wang, Ying-Ying Lin, Canhua Huang, Yue-Nan Li, Hao-Fu Dai, Guang-Hong Tan
Theranostics 2018; 8(7): 2044-2060. doi:10.7150/thno.23304
[Abstract] [Full text] [PDF]


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Research Paper
α-Viniferin Improves Facial Hyperpigmentation via Accelerating Feedback Termination of cAMP/PKA-Signaled Phosphorylation Circuit in Facultative Melanogenesis
Cheong-Yong Yun, Seon Mi Ko, Yong Pyo Choi, Beom Joon Kim, Jungno Lee, Jae Mun Kim, Ju Yeon Kim, Jin Yong Song, Song-Hee Kim, Bang Yeon Hwang, Jin Tae Hong, Sang-Bae Han, Youngsoo Kim
Theranostics 2018; 8(7): 2031-2043. doi:10.7150/thno.24385
[Abstract] [Full text] [PDF]


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Research Paper
A paclitaxel prodrug with bifunctional folate and albumin binding moieties for both passive and active targeted cancer therapy
Lingling Shan, Xin Zhuo, Fuwu Zhang, Yunlu Dai, Guizhi Zhu, Bryant C. Yung, Wenpei Fan, Kefeng Zhai, Orit Jacobson, Dale O. Kiesewetter, Ying Ma, Guizhen Gao, Xiaoyuan Chen
Theranostics 2018; 8(7): 2018-2030. doi:10.7150/thno.24382
[Abstract] [Full text] [PDF]


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Review
Applications of gold nanoparticles in virus detection
Mohamed Shehata Draz, Hadi Shafiee
Theranostics 2018; 8(7): 1985-2017. doi:10.7150/thno.23856
[Abstract] [Full text] [PDF]


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Research Paper
Dual Chemodrug-Loaded Single-Walled Carbon Nanohorns for Multimodal Imaging-Guided Chemo-Photothermal Therapy of Tumors and Lung Metastases
Jingxing Yang, Huilan Su, Wenshe Sun, Jiali Cai, Shiyuan Liu, Yimin Chai, Chunfu Zhang
Theranostics 2018; 8(7): 1966-1984. doi:10.7150/thno.23848
[Abstract] [Full text] [PDF]


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Research Paper
Integrative analysis of imaging and transcriptomic data of the immune landscape associated with tumor metabolism in lung adenocarcinoma: Clinical and prognostic implications
Hongyoon Choi, Kwon Joong Na
Theranostics 2018; 8(7): 1956-1965. doi:10.7150/thno.23767
[Abstract] [Full text] [PDF]


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Research Paper
Bioactive Scaffolds for Regeneration of Cartilage and Subchondral Bone Interface
Cuijun Deng, Huiying Zhu, Jiayi Li, Chun Feng, Qingqiang Yao, Liming Wang, Jiang Chang, Chengtie Wu
Theranostics 2018; 8(7): 1940-1955. doi:10.7150/thno.23674
[Abstract] [Full text] [PDF]


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Research Paper
UTMD-Promoted Co-Delivery of Gemcitabine and miR-21 Inhibitor by Dendrimer-Entrapped Gold Nanoparticles for Pancreatic Cancer Therapy
Lizhou Lin, Yu Fan, Feng Gao, Lifang Jin, Dan Li, Wenjie Sun, Fan Li, Peng Qin, Qiusheng Shi, Xiangyang Shi, Lianfang Du
Theranostics 2018; 8(7): 1923-1939. doi:10.7150/thno.22834
[Abstract] [Full text] [PDF]


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Research Paper
Novel Self-assembled Organic Nanoprobe for Molecular Imaging and Treatment of Gram-positive Bacterial Infection
Tang Gao, Hongliang Zeng, Huan Xu, Feng Gao, Wei Li, Shengwang Zhang, Yi Liu, Guifang Luo, Mingdan Li, Dejian Jiang, Zhigao Chen, Yong Wu, Wei Wang, Wenbin Zeng
Theranostics 2018; 8(7): 1911-1922. doi:10.7150/thno.22534
[Abstract] [Full text] [PDF]


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Research Paper
Cell-penetrating Peptide-modified Targeted Drug-loaded Phase-transformation Lipid Nanoparticles Combined with Low-intensity Focused Ultrasound for Precision Theranostics against Hepatocellular Carcinoma
Hongyun Zhao, Meng Wu, Leilei Zhu, Yi Tian, Mingxing Wu, Yizhen Li, Liming Deng, Wei Jiang, Wei Shen, Zhigang Wang, Zhechuan Mei, Pan Li, Haitao Ran, Zhiyi Zhou, Jianli Ren
Theranostics 2018; 8(7): 1892-1910. doi:10.7150/thno.22386
[Abstract] [Full text] [PDF]


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Research Paper
Ultrasound Molecular Imaging of Atherosclerosis for Early Diagnosis and Therapeutic Evaluation through Leucocyte-like Multiple Targeted Microbubbles
Fei Yan, Yu Sun, Yang Mao, Meiying Wu, Zhiting Deng, Shuai Li, Xin Liu, Li Xue, Hairong Zheng
Theranostics 2018; 8(7): 1879-1891. doi:10.7150/thno.22070
[Abstract] [Full text] [PDF]


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Research Paper
Targeting regenerative exosomes to myocardial infarction using cardiac homing peptide
Adam Vandergriff, Ke Huang, Deliang Shen, Shiqi Hu, Michael Taylor Hensley, Thomas G. Caranasos, Li Qian, Ke Cheng
Theranostics 2018; 8(7): 1869-1878. doi:10.7150/thno.20524
[Abstract] [Full text] [PDF]


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Research Paper
Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma
Silvia Di Agostino, Fabio Valenti, Andrea Sacconi, Giulia Fontemaggi, Matteo Pallocca, Claudio Pulito, Federica Ganci, Paola Muti, Sabrina Strano, Giovanni Blandino
Theranostics 2018; 8(7): 1850-1868. doi:10.7150/thno.22167
[Abstract] [Full text] [PDF]


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Review
Metal-based NanoEnhancers for Future Radiotherapy: Radiosensitizing and Synergistic Effects on Tumor Cells
Yan Liu, Pengcheng Zhang, Feifei Li, Xiaodong Jin, Jin Li, Weiqiang Chen, Qiang Li
Theranostics 2018; 8(7): 1824-1849. doi:10.7150/thno.22172
[Abstract] [Full text] [PDF]


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Research Paper
Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase
Jiang-Kai Dong, Hui-Min Lei, Qian Liang, Ya-Bin Tang, Ye Zhou, Yang Wang, Shengzhe Zhang, Wen-Bin Li, Yunguang Tong, Guanglei Zhuang, Liang Zhang, Hong-Zhuan Chen, Liang Zhu, Ying Shen
Theranostics 2018; 8(7): 1808-1823. doi:10.7150/thno.23177
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

new Nanotheranostics in PubMed Central

Theme Issue on “Brain Theranostics. Guest Editor: Prof. Rachela Popovtzer, PhD
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Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues