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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
Dosimetric evaluation of radionuclides for VCAM-1-targeted radionuclide therapy of early brain metastases
Nadia Falzone, Nicole L. Ackerman, Liset de la Fuente Rosales, Mario A. Bernal, Xiaoxuan Liu, Sarah GJA Peeters, Manuel Sarmiento Soto, Aurélien Corroyer-Dulmont, Myriam Bernaudin, Elisa Grimoin, Omar Touzani, Nicola R. Sibson, Katherine A. Vallis
Theranostics 2018; 8(1): 292-303. doi:10.7150/thno.22217
[Abstract] [Full text] [PDF]


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Research Paper
Tiresias: Context-sensitive Approach to Decipher the Presence and Strength of MicroRNA Regulatory Interactions
Jinkyu Koo, Jinyi Zhang, Somali Chaterji
Theranostics 2018; 8(1): 277-291. doi:10.7150/thno.22065
[Abstract] [Full text] [PDF]


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Research Paper
Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution
Bhavesh D. Kevadiya, Christopher Woldstad, Brendan M. Ottemann, Prasanta Dash, Balasrinivasa R. Sajja, Benjamin Lamberty, Brenda Morsey, Ted Kocher, Rinku Dutta, Aditya N. Bade, Yutong Liu, Shannon E. Callen, Howard S. Fox, Siddappa N. Byrareddy, JoEllyn M. McMillan, Tatiana K. Bronich, Benson J. Edagwa, Michael D. Boska, Howard E. Gendelman
Theranostics 2018; 8(1): 256-276. doi:10.7150/thno.22764
[Abstract] [Full text] [PDF]


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Review
Exosome Theranostics: Biology and Translational Medicine
Chuanjiang He, Shu Zheng, Yan Luo, Ben Wang
Theranostics 2018; 8(1): 237-255. doi:10.7150/thno.21945
[Abstract] [Full text] [PDF]


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Research Paper
An Albumin-binding Polypeptide Both Targets Cytotoxic T Lymphocyte Vaccines to Lymph Nodes and Boosts Vaccine Presentation by Dendritic Cells
Peng Wang, Peng Zhao, Shuyun Dong, Tiefeng Xu, Xiao He, Mingnan Chen
Theranostics 2018; 8(1): 223-236. doi:10.7150/thno.21691
[Abstract] [Full text] [PDF]


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Research Paper
Glutathione Peroxidase 3 Delivered by hiPSC-MSCs Ameliorated Hepatic IR Injury via Inhibition of Hepatic Senescence
Xiang Qi, Kevin Tak-Pan Ng, Qizhou Lian, Chang Xian Li, Wei Geng, Chang Chun Ling, Wai Ho Yeung, Yuen Yuen Ma, Xiao Bing Liu, Hui Liu, Jiang Liu, Xin Xiang Yang, Chung Mau Lo, Kwan Man
Theranostics 2018; 8(1): 212-222. doi:10.7150/thno.21656
[Abstract] [Full text] [PDF]


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Research Paper
Histidine-rich Modification of a Scorpion-derived Peptide Improves Bioavailability and Inhibitory Activity against HSV-1
Zhengyang Zeng, Runhong Zhang, Wei Hong, Yuting Cheng, Huijuan Wang, Yange Lang, Zhenglin Ji, Yingliang Wu, Wenxin Li, Youli Xie, Zhijian Cao
Theranostics 2018; 8(1): 199-211. doi:10.7150/thno.21425
[Abstract] [Full text] [PDF]


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Research Paper
RHCG Suppresses Tumorigenicity and Metastasis in Esophageal Squamous Cell Carcinoma via Inhibiting NF-κB Signaling and MMP1 Expression
Xiao-Yan Ming, Xu Zhang, Ting-Ting Cao, Li-Yi Zhang, Jia-Li Qi, Ngar-Woon Kam, Xu-Ming Tang, Yu-Zhu Cui, Bao-Zhu Zhang, Yan Li, Yan-Ru Qin, Xin-Yuan Guan
Theranostics 2018; 8(1): 185-198. doi:10.7150/thno.21383
[Abstract] [Full text] [PDF]


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Research Paper
Exosomes from human umbilical cord blood accelerate cutaneous wound healing through miR-21-3p-mediated promotion of angiogenesis and fibroblast function
Yin Hu, Shan-Shan Rao, Zhen-Xing Wang, Jia Cao, Yi-Juan Tan, Juan Luo, Hong-Ming Li, Wei-She Zhang, Chun-Yuan Chen, Hui Xie
Theranostics 2018; 8(1): 169-184. doi:10.7150/thno.21234
[Abstract] [Full text] [PDF]


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Research Paper
Early Assessment of Tumor Response to Radiation Therapy using High-Resolution Quantitative Microvascular Ultrasound Imaging
Sandeep K. Kasoji, Judith N. Rivera, Ryan C. Gessner, Sha X. Chang, Paul A. Dayton
Theranostics 2018; 8(1): 156-168. doi:10.7150/thno.19703
[Abstract] [Full text] [PDF]


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Research Paper
Ultrasound Molecular Imaging of VEGFR-2 in Clear-Cell Renal Cell Carcinoma Tracks Disease Response to Antiangiogenic and Notch-Inhibition Therapy
Juan D. Rojas, Fanglue Lin, Yun-Chen Chiang, Anna Chytil, Diana C. Chong, Victoria L. Bautch, W. Kimryn Rathmell, Paul A. Dayton
Theranostics 2018; 8(1): 141-155. doi:10.7150/thno.19658
[Abstract] [Full text] [PDF]


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Research Paper
Engineered Microenvironments for Maturation of Stem Cell Derived Cardiac Myocytes
Rachel R. Besser, Matthew Ishahak, Vera Mayo, Daniel Carbonero, Isabella Claure, Ashutosh Agarwal
Theranostics 2018; 8(1): 124-140. doi:10.7150/thno.19441
[Abstract] [Full text] [PDF]


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Research Paper
PrLZ increases prostate cancer docetaxel resistance by inhibiting LKB1/AMPK-mediated autophagy
Jin Zeng, Wei Liu, Yi-Zeng Fan, Da-Lin He, Lei Li
Theranostics 2018; 8(1): 109-123. doi:10.7150/thno.20356
[Abstract] [Full text] [PDF]


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Research Paper
Tumor-penetrating Peptide Conjugated and Doxorubicin Loaded T1-T2 Dual Mode MRI Contrast Agents Nanoparticles for Tumor Theranostics
Lipeng Gao, Jing Yu, Yang Liu, Jinge Zhou, Lei Sun, Jing Wang, Jianzhong Zhu, Hui Peng, Weiyue Lu, Lei Yu, Zhiqiang Yan, Yiting Wang
Theranostics 2018; 8(1): 92-108. doi:10.7150/thno.21074
[Abstract] [Full text] [PDF]


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Research Paper
A Mucin1 C-terminal Subunit-directed Monoclonal Antibody Targets Overexpressed Mucin1 in Breast Cancer
Guang Wu, Dongbum Kim, Jung Nam Kim, Sangkyu Park, Sony Maharjan, Heeju Koh, Kyungduk Moon, Younghee Lee, Hyung-Joo Kwon
Theranostics 2018; 8(1): 78-91. doi:10.7150/thno.21278
[Abstract] [Full text] [PDF]


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Research Paper
Epigenomic characterization of a p53-regulated 3p22.2 tumor suppressor that inhibits STAT3 phosphorylation via protein docking and is frequently methylated in esophageal and other carcinomas
Lili Li, Juan Xu, Guohua Qiu, Jianming Ying, Zhenfang Du, Tingxiu Xiang, Kai Yau Wong, Gopesh Srivastava, Xiao-Feng Zhu, Tony S Mok, Anthony TC Chan, Francis KL Chan, Richard F Ambinder, Qian Tao
Theranostics 2018; 8(1): 61-77. doi:10.7150/thno.20893
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

new Nanotheranostics in PubMed Central

Theme Issue on “Brain Theranostics. Guest Editor: Prof. Rachela Popovtzer, PhD
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Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues