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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.


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Research Paper
MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance
Xin Lai, Shailendra K Gupta, Ulf Schmitz, Stephan Marquardt, Susanne Knoll, Alf Spitschak, Olaf Wolkenhauer, Brigitte M Pützer, Julio Vera
Theranostics 2018; 8(4): 1106-1120. doi:10.7150/thno.19904
[Abstract] [Full text] [PDF]


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Research Paper
PIWIL3/OIP5-AS1/miR-367-3p/CEBPA feedback loop regulates the biological behavior of glioma cells
Xiaobai Liu, Jian Zheng, Yixue Xue, Hai Yu, Wei Gong, Ping Wang, Zhen Li, Yunhui Liu
Theranostics 2018; 8(4): 1084-1105. doi:10.7150/thno.21740
[Abstract] [Full text] [PDF]


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Research Paper
Nondestructive Analysis of Tumor-Associated Membrane Protein Integrating Imaging and Amplified Detection in situ Based on Dual-Labeled DNAzyme
Xiaoxia Chen, Jing Zhao, Tianshu Chen, Tao Gao, Xiaoli Zhu, Genxi Li
Theranostics 2018; 8(4): 1075-1083. doi:10.7150/thno.22794
[Abstract] [Full text] [PDF]


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Review
Stimuli-Responsive Nanomedicines for Overcoming Cancer Multidrug Resistance
Lei Zhou, Hao Wang, Yaping Li
Theranostics 2018; 8(4): 1059-1074. doi:10.7150/thno.22679
[Abstract] [Full text] [PDF]


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Research Paper
Octopod PtCu Nanoframe for Dual-Modal Imaging-Guided Synergistic Photothermal Radiotherapy
Jinghua Li, Xiangyang Zu, Gaofeng Liang, KeKe Zhang, Yuliang Liu, Ke Li, Zhong Luo, Kaiyong Cai
Theranostics 2018; 8(4): 1042-1058. doi:10.7150/thno.22557
[Abstract] [Full text] [PDF]


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Research Paper
Targeting ALDH2 for Therapeutic Interventions in Chronic Pain-Related Myocardial Ischemic Susceptibility
Chen Li, Wanqing Sun, Chunhu Gu, Zheng Yang, Nanhu Quan, Jingrun Yang, Zhaoling Shi, Lu Yu, Heng Ma
Theranostics 2018; 8(4): 1027-1041. doi:10.7150/thno.22414
[Abstract] [Full text] [PDF]


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Review
Black Phosphorus and its Biomedical Applications
Jane Ru Choi, Kar Wey Yong, Jean Yu Choi, Azadeh Nilghaz, Yang Lin, Jie Xu, Xiaonan Lu
Theranostics 2018; 8(4): 1005-1026. doi:10.7150/thno.22573
[Abstract] [Full text] [PDF]


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Research Paper
O2-generating MnO2 nanoparticles for enhanced photodynamic therapy of bladder cancer by ameliorating hypoxia
Tingsheng Lin, Xiaozhi Zhao, Sheng Zhao, Hang Yu, Wenmin Cao, Wei Chen, Hui Wei, Hongqian Guo
Theranostics 2018; 8(4): 990-1004. doi:10.7150/thno.22465
[Abstract] [Full text] [PDF]


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Research Paper
The Homeotic Protein SIX3 Suppresses Carcinogenesis and Metastasis through Recruiting the LSD1/NuRD(MTA3) Complex
Yu Zheng, Yi Zeng, Rongfang Qiu, Ruiqiong Liu, Wei Huang, Yongqiang Hou, Shuang Wang, Shuai Leng, Dandan Feng, Yang Yang, Yan Wang
Theranostics 2018; 8(4): 972-989. doi:10.7150/thno.22328
[Abstract] [Full text] [PDF]


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Research Paper
All-in-One Theranostic Nanoplatform Based on Hollow MoSx for Photothermally-maneuvered Oxygen Self-enriched Photodynamic Therapy
Jinping Wang, Li Liu, Qing You, Yilin Song, Qi Sun, Yidan Wang, Yu Cheng, Fengping Tan, Nan Li
Theranostics 2018; 8(4): 955-971. doi:10.7150/thno.22325
[Abstract] [Full text] [PDF]


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Research Paper
Investigating the Intracellular Behaviors of Liposomal Nanohybrids via SERS: Insights into the Influence of Metal Nanoparticles
Dan Zhu, Zhuyuan Wang, Shenfei Zong, Yizhi Zhang, Chen Chen, Ruohu Zhang, Binfeng Yun, Yiping Cui
Theranostics 2018; 8(4): 941-954. doi:10.7150/thno.21173
[Abstract] [Full text] [PDF]


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Research Paper
Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway
Xing Qin, Ming Yan, Xu Wang, Qin Xu, Xiaoning Wang, Xueqin Zhu, Jianbo Shi, Zhihui Li, Jianjun Zhang, Wantao Chen
Theranostics 2018; 8(4): 921-940. doi:10.7150/thno.22182
[Abstract] [Full text] [PDF]


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Research Paper
Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro
Lucienne A. Vonk, Sanne F. J. van Dooremalen, Nalan Liv, Judith Klumperman, Paul J. Coffer, Daniël B.F. Saris, Magdalena J. Lorenowicz
Theranostics 2018; 8(4): 906-920. doi:10.7150/thno.20746
[Abstract] [Full text] [PDF]


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Research Paper
Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development
Yun-Chieh Sung, Ya-Chi Liu, Po-Han Chao, Chih-Chun Chang, Pei-Ru Jin, Ts-Ting Lin, Ja-An Lin, Hui-Teng Cheng, Jane Wang, Charles P. Lai, Ling-Hsuan Chen, Anthony Y. Wu, Ting-Lun Ho, Tsaiyu Chiang, Dong-Yu Gao, Dan G. Duda, Yunching Chen
Theranostics 2018; 8(4): 894-905. doi:10.7150/thno.21168
[Abstract] [Full text] [PDF]


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Research Paper
Sustained Release of Immunosuppressant by Nanoparticle-anchoring Hydrogel Scaffold Improved the Survival of Transplanted Stem Cells and Tissue Regeneration
Ruixiang Li, Jianming Liang, Yuwei He, Jing Qin, Huining He, Seungjin Lee, Zhiqing Pang, Jianxin Wang
Theranostics 2018; 8(4): 878-893. doi:10.7150/thno.22072
[Abstract] [Full text] [PDF]


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Editorial
LET's sponge: How the lncRNA PFL promotes cardiac fibrosis
Matthias S. Leisegang
Theranostics 2018; 8(4): 874-877. doi:10.7150/thno.23364
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile

Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/

new Nanotheranostics in PubMed Central

Theme Issue on “Brain Theranostics. Guest Editor: Prof. Rachela Popovtzer, PhD
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Most Cited Paper Award for year 2016: Winners of this year are Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He, for the paper "Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers". Details ...

Dr. Chen was recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/

Dr. Chen received the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.

NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues