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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Latest articles:


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Research Paper
Reversal of Vascular Calcification and Aneurysms in a Rat Model Using Dual Targeted Therapy with EDTA- and PGG-Loaded Nanoparticles
Nasim Nosoudi, Aniqa Chowdhury, Steven Siclari, Saketh Karamched, Vaideesh Parasaram, Joe Parrish, Patrick Gerard, Narendra Vyavahare
Theranostics 2016; 6(11): 1975-1987. doi:10.7150/thno.16547
[Abstract] [Full text] [PDF]


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Research Paper
Motion Compensated Ultrasound Imaging Allows Thermometry and Image Guided Drug Delivery Monitoring from Echogenic Liposomes
Kalyani Ektate, Ankur Kapoor, Danny Maples, Ahmet Tuysuzoglu, Joshua VanOsdol, Selvarani Ramasami, Ashish Ranjan
Theranostics 2016; 6(11): 1963-1974. doi:10.7150/thno.15922
[Abstract] [Full text] [PDF]


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Research Paper
Depletion of γ-catenin by Histone Deacetylase Inhibition Confers Elimination of CML Stem Cells in Combination with Imatinib
Yanli Jin, Yiwu Yao, Li Chen, Xiaohui Zhu, Bei Jin, Yingying Shen, Juan Li, Xin Du, Yuhong Lu, Sheng Jiang, Jingxuan Pan
Theranostics 2016; 6(11): 1947-1962. doi:10.7150/thno.16139
[Abstract] [Full text] [PDF]


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Research Paper
The Clinical Significance and Potential Therapeutic Role of GPx3 in Tumor Recurrence after Liver Transplantation
Xiang Qi, Kevin Tak-Pan Ng, Yan Shao, Chang Xian Li, Wei Geng, Chang Chun Ling, Yuen Yuen Ma, Xiao Bing Liu, Hui Liu, Jiang Liu, Wai Ho Yeung, Chung Mau Lo, Kwan Man
Theranostics 2016; 6(11): 1934-1946. doi:10.7150/thno.16023
[Abstract] [Full text] [PDF]


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Research Paper
CD146-targeted immunoPET and NIRF Imaging of Hepatocellular Carcinoma with a Dual-Labeled Monoclonal Antibody
Reinier Hernandez, Haiyan Sun, Christopher G. England, Hector F. Valdovinos, Emily B. Ehlerding, Todd E. Barnhart, Yunan Yang, Weibo Cai
Theranostics 2016; 6(11): 1918-1933. doi:10.7150/thno.15568
[Abstract] [Full text] [PDF]


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Research Paper
Melatonin Treatment Improves Mesenchymal Stem Cells Therapy by Preserving Stemness during Long-term In Vitro Expansion
Yi Shuai, Li Liao, Xiaoxia Su, Yang Yu, Bingyi Shao, Huan Jing, Xinjing Zhang, Zhihong Deng, Yan Jin
Theranostics 2016; 6(11): 1899-1917. doi:10.7150/thno.15412
[Abstract] [Full text] [PDF]


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Research Paper
Targeting Negative Surface Charges of Cancer Cells by Multifunctional Nanoprobes
Bingdi Chen, Wenjun Le, Yilong Wang, Zhuoquan Li, Dong Wang, Ling Lin, Shaobin Cui, Jennifer J. Hu, Yihui Hu, Pengyuan Yang, Rodney C. Ewing, Donglu Shi, Zheng Cui
Theranostics 2016; 6(11): 1887-1898. doi:10.7150/thno.16358
[Abstract] [Full text] [PDF]


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Research Paper
Aptamer-Mediated Transparent-Biocompatible Nanostructured Surfaces for Hepotocellular Circulating Tumor Cells Enrichment
Shuyi Wang, Chunxiao Zhang, Guozhou Wang, Boran Cheng, Yulei Wang, Fangfang Chen, Yuanyuan Chen, Maohui Feng, Bin Xiong
Theranostics 2016; 6(11): 1877-1886. doi:10.7150/thno.15284
[Abstract] [Full text] [PDF]


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Research Paper
Blinking Phase-Change Nanocapsules Enable Background-Free Ultrasound Imaging
Alexander S. Hannah, Geoffrey P. Luke, Stanislav Y. Emelianov
Theranostics 2016; 6(11): 1866-1876. doi:10.7150/thno.14961
[Abstract] [Full text] [PDF]


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Research Paper
In vivo Biocompatibility, Biodistribution and Therapeutic Efficiency of Titania Coated Upconversion Nanoparticles for Photodynamic Therapy of Solid Oral Cancers
Sasidharan Swarnalatha Lucky, Niagara Muhammad Idris, Kai Huang, Jaejung Kim, Zhengquan Li, Patricia Soo Ping Thong, Rong Xu, Khee Chee Soo, Yong Zhang
Theranostics 2016; 6(11): 1844-1865. doi:10.7150/thno.15088
[Abstract] [Full text] [PDF]


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Research Paper
Polydopamine Coated Single-Walled Carbon Nanotubes as a Versatile Platform with Radionuclide Labeling for Multimodal Tumor Imaging and Therapy
He Zhao, Yu Chao, Jingjing Liu, Jie Huang, Jian Pan, Wanliang Guo, Jizhi Wu, Mao Sheng, Kai Yang, Jian Wang, Zhuang Liu
Theranostics 2016; 6(11): 1833-1843. doi:10.7150/thno.16047
[Abstract] [Full text] [PDF]


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Research Paper
Potentiation of Peptide Receptor Radionuclide Therapy by the PARP Inhibitor Olaparib
Julie Nonnekens, Melissa van Kranenburg, Cecile E.M.T. Beerens, Mustafa Suker, Michael Doukas, Casper H.J. van Eijck, Marion de Jong, Dik C. van Gent
Theranostics 2016; 6(11): 1821-1832. doi:10.7150/thno.15311
[Abstract] [Full text] [PDF]


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Research Paper
Silica Nanoparticles Target a Wnt Signal Transducer for Degradation and Impair Embryonic Development in Zebrafish
Hongyang Yi, Zhuyao Wang, Xiaojiao Li, Min Yin, Lihua Wang, Ali Aldalbahi, Nahed Nasser El-Sayed, Hui Wang, Nan Chen, Chunhai Fan, Haiyun Song
Theranostics 2016; 6(11): 1810-1820. doi:10.7150/thno.16127
[Abstract] [Full text] [PDF]


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Research Paper
Peripheral Blood Cell Gene Expression Diagnostic for Identifying Symptomatic Transthyretin Amyloidosis Patients: Male and Female Specific Signatures
Sunil M. Kurian, Marta Novais, Thomas Whisenant, Terri Gelbart, Joel N. Buxbaum, Jeffery W. Kelly, Teresa Coelho, Daniel R. Salomon
Theranostics 2016; 6(11): 1792-1809. doi:10.7150/thno.14584
[Abstract] [Full text] [PDF]


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Research Paper
Active-target T1-weighted MR Imaging of Tiny Hepatic Tumor via RGD Modified Ultra-small Fe3O4 Nanoprobes
Zhengyang Jia, Lina Song, Fengchao Zang, Jiacheng Song, Wei Zhang, Changzhi Yan, Jun Xie, Zhanlong Ma, Ming Ma, Gaojun Teng, Ning Gu, Yu Zhang
Theranostics 2016; 6(11): 1780-1791. doi:10.7150/thno.14280
[Abstract] [Full text] [PDF]


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Research Paper
Targeting Amino Acid Metabolism for Molecular Imaging of Inflammation Early After Myocardial Infarction
James T. Thackeray, Jens P. Bankstahl, Yong Wang, Kai C. Wollert, Frank M. Bengel
Theranostics 2016; 6(11): 1768-1779. doi:10.7150/thno.15929
[Abstract] [Full text] [PDF]

Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD, Chief, Laboratory of Molecular Imaging and Nanomedicine, NIBIB, NIH*
* Dr. Chen is serving in his personal capacity.
Editor-in-chief profile
new Impact factor is 8.854, according to 2016 release of Journal Citation Reports®. Congratulations!

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Most Cited Paper Award for year 2015: Winners of this year are Chao Wang, Liang Cheng, Zhuang Liu, for the paper "Upconversion Nanoparticles for Photodynamic Therapy and Other Cancer Therapeutics". Details ...
Theme Issue on “Biomolecular and biomimetic materials for theranostics. Guest Editors: Haiyun Song, PhD, and Chunhai Fan, PhD
Theme Issue on “Translational theranostics for infectious diseases. Guest Editor: Dr. Tony Y. Hu, Houston Methodist Research Institute
Theme Issue on “Light-Mediated Deep-Tissue Theranostics. Guest Editors: Dr. Gang Han, University of Massachusetts Medical School, and Dr. Jin Xie, University of Georgia
new Congratulations to Dr. Chen for receiving the 2016 Bioconjugate Chemistry Lectureship Award for his extensive contributions at the interface between chemistry, biology, and medicine that have helped define the field of nanomedicine.
NCI provides a data repository for characterized cancer nanomaterials, the cancer Nanotechnology Laboratory (caNanoLab). Authors and readers of Theranostics are invited to learn more about the information deposited and how they can add their characterized nanomaterials data.
Office of Cancer Nanotechnology Research in NCI has publicly launched a Dialogue on Nanotechnology in Cancer public discussion forum. Readers of Theranostics are invited to participate in this dialog.
Media coverage: Dr. Chen and Theranostics journal have been featured in an article of Laser Focus World magazine, and in C&EN (Chemical and Engineering News).
Published Special Issues