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Volume 7 (18); 2017

Research Paper

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Identification and Validation of a Salivary Protein Panel to Detect Heart Failure Early
Xi Zhang, Terry Walsh, John J Atherton, Karam Kostner, Benjamin Schulz, Chamindie Punyadeera
Theranostics 2017; 7(18): 4350-4358. doi:10.7150/thno.21727
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Clinical Translation and First In-Human Use of [44Sc]Sc-PSMA-617 for PET Imaging of Metastasized Castrate-Resistant Prostate Cancer
Elisabeth Eppard, Ana de la Fuente, Martina Benešová, Ambreen Khawar, Ralph A. Bundschuh, Florian C. Gärtner, Barbara Kreppel, Klaus Kopka, Markus Essler, Frank Rösch
Theranostics 2017; 7(18): 4359-4369. doi:10.7150/thno.20586
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Human Umbilical Cord MSCs as New Cell Sources for Promoting Periodontal Regeneration in Inflammatory Periodontal Defect
Fengqing Shang, Shiyu Liu, Leiguo Ming, Rong Tian, Fang Jin, Yin Ding, Yongjie Zhang, Hongmei Zhang, Zhihong Deng, Yan Jin
Theranostics 2017; 7(18): 4370-4382. doi:10.7150/thno.19888
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Rational design of Polymeric Hybrid Micelles to Overcome Lymphatic and Intracellular Delivery Barriers in Cancer Immunotherapy
Hanmei Li, Yanping Li, Xue Wang, Yingying Hou, Xiaoyu Hong, Tao Gong, Zhirong Zhang, Xun Sun
Theranostics 2017; 7(18): 4383-4398. doi:10.7150/thno.20745
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Theranostic Role of 32P-ATP as Radiopharmaceutical for the Induction of Massive Cell Death within Avascular Tumor Core
Mirco Galiè, Federico Boschi, Ilaria Scambi, Flavia Merigo, Pasquina Marzola, Luisa Altabella, Umberto Lavagnolo, Andrea Sbarbati, Antonello E Spinelli
Theranostics 2017; 7(18): 4399-4409. doi:10.7150/thno.21403
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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A Laser-Activated Biocompatible Theranostic Nanoagent for Targeted Multimodal Imaging and Photothermal Therapy
Liming Deng, Xiaojun Cai, Danli Sheng, Yang Yang, Eric M. Strohm, Zhigang Wang, Haitao Ran, Dong Wang, Yuanyi Zheng, Pan Li, Tingting Shang, Yi Ling, Fengjuan Wang, Yang Sun
Theranostics 2017; 7(18): 4410-4423. doi:10.7150/thno.21283
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Temperature-Sensitive Gold Nanoparticle-Coated Pluronic-PLL Nanoparticles for Drug Delivery and Chemo-Photothermal Therapy
Ying Sun, Qi Wang, Jianhua Chen, Lei Liu, Li Ding, Ming Shen, Jin Li, Baoshan Han, Yourong Duan
Theranostics 2017; 7(18): 4424-4444. doi:10.7150/thno.18832
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Characterization of Cardiac Dynamics in an Acute Myocardial Infarction Model by Four-Dimensional Optoacoustic and Magnetic Resonance Imaging
Hsiao-Chun Amy Lin, Xosé Luís Déan-Ben, Ivana Ivankovic, Melanie A. Kimm, Katja Kosanke, Helena Haas, Reinhard Meier, Fabian Lohöfer, Moritz Wildgruber, Daniel Razansky
Theranostics 2017; 7(18): 4470-4479. doi:10.7150/thno.20616
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Inorganic Kernel-Reconstituted Lipoprotein Biomimetic Nanovehicles Enable Efficient Targeting “Trojan Horse” Delivery of STAT3-Decoy Oligonucleotide for Overcoming TRAIL Resistance
Kai Shi, Jianxiu Xue, Yan Fang, Hongshu Bi, Shan Gao, Dongjuan Yang, Anqi Lu, Yuai Li, Yao Chen, Liyuan Ke
Theranostics 2017; 7(18): 4480-4497. doi:10.7150/thno.21707
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis
Meng Qi, Liqiang Zhang, Yang Ma, Yi Shuai, Liya Li, Kefu Luo, Wenjia Liu, Yan Jin
Theranostics 2017; 7(18): 4498-4516. doi:10.7150/thno.17949
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Locoregional Confinement and Major Clinical Benefit of 188Re-Loaded CXCR4-Targeted Nanocarriers in an Orthotopic Human to Mouse Model of Glioblastoma
Delphine Séhédic, Igor Chourpa, Clément Tétaud, Audrey Griveau, Claire Loussouarn, Sylvie Avril, Claire Legendre, Nicolas Lepareur, Didier Wion, François Hindré, François Davodeau, Emmanuel Garcion
Theranostics 2017; 7(18): 4517-4536. doi:10.7150/thno.19403
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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pH-Responsive Aerobic Nanoparticles for Effective Photodynamic Therapy
Lingyue Shen, Yu Huang, Dong Chen, Feng Qiu, Chuan Ma, Xin Jin, Xinyuan Zhu, Guoyu Zhou, Zhiyuan Zhang
Theranostics 2017; 7(18): 4537-4550. doi:10.7150/thno.19546
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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In-Tether Chiral Center Induced Helical Peptide Modulators Target p53-MDM2/MDMX and Inhibit Tumor Growth in Stem-Like Cancer Cell
Kuan Hu, Feng Yin, Mengyin Yu, Chengjie Sun, Jingxu Li, Yujie Liang, Wenjun Li, Mingsheng Xie, Yuanzhi Lao, Wei Liang, Zi-gang Li
Theranostics 2017; 7(18): 4566-4576. doi:10.7150/thno.19840
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Subcellular Localization of Survivin Determines Its Function in Cardiomyocytes
Tien-Jui Tsang, Ying-Chang Hsueh, Erika I. Wei, David J. Lundy, Bill Cheng, You-Tzung Chen, Shoei-Shen Wang, Patrick C.H. Hsieh
Theranostics 2017; 7(18): 4577-4590. doi:10.7150/thno.20005
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Photoactive Poly(3-hexylthiophene) Nanoweb for Optoelectrical Stimulation to Enhance Neurogenesis of Human Stem Cells
Kisuk Yang, Jin Young Oh, Jong Seung Lee, Yoonhee Jin, Gyeong-Eon Chang, Soo Sang Chae, Eunji Cheong, Hong Koo Baik, Seung-Woo Cho
Theranostics 2017; 7(18): 4591-4604. doi:10.7150/thno.20169
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Biodegradable Core-shell Dual-Metal-Organic-Frameworks Nanotheranostic Agent for Multiple Imaging Guided Combination Cancer Therapy
Dongdong Wang, Jiajia Zhou, Ruohong Shi, Huihui Wu, Ruhui Chen, Beichen Duan, Guoliang Xia, Pengping Xu, Hui Wang, Shu Zhou, Chengming Wang, Haibao Wang, Zhen Guo, Qianwang Chen
Theranostics 2017; 7(18): 4605-4617. doi:10.7150/thno.20363
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Enhanced antitumor efficacy of biocompatible magnetosomes for the magnetic hyperthermia treatment of glioblastoma
Raphaël Le Fèvre, Mickaël Durand-Dubief, Imène Chebbi, Chalani Mandawala, France Lagroix, Jean-Pierre Valet, Ahmed Idbaih, Clovis Adam, Jean-Yves Delattre, Charlotte Schmitt, Caroline Maake, François Guyot, Edouard Alphandéry
Theranostics 2017; 7(18): 4618-4631. doi:10.7150/thno.18927
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity via Direct Binding to the STAT3 DNA-Binding Domain
Dong Ju Son, Jie Zheng, Yu Yeon Jung, Chul Ju Hwang, Hee Pom Lee, Ju Rang Woo, Song Yi Baek, Young Wan Ham, Min Woong Kang, Minho Shong, Gi Ryang Kweon, Min Jong Song, Jae Kyung Jung, Sang-Bae Han, Bo Yeon Kim, Do Young Yoon, Bu Young Choi, Jin Tae Hong
Theranostics 2017; 7(18): 4632-4642. doi:10.7150/thno.18630
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

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CRISPR Genome Engineering for Human Pluripotent Stem Cell Research
Somali Chaterji, Eun Hyun Ahn, Deok-Ho Kim
Theranostics 2017; 7(18): 4445-4469. doi:10.7150/thno.18456
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Quantitative Imaging for Targeted Radionuclide Therapy Dosimetry - Technical Review
Tiantian Li, Edwin C. I. Ao, Bieke Lambert, Boudewijn Brans, Stefaan Vandenberghe, Greta S. P. Mok
Theranostics 2017; 7(18): 4551-4565. doi:10.7150/thno.19782
[Abstract] [Full text] [PDF] [PubMed] [PMC]