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Volume 14 (14); 2024

Research Papers

Graphic abstract

The heterobivalent (SSTR2/albumin) radioligand [67Cu]Cu-NODAGA-cLAB4-TATE enables efficient somatostatin receptor radionuclide theranostics
Martin Ullrich, Robert Wodtke, Florian Brandt, Robert Freudenberg, Jörg Kotzerke, Susan Richter, Klaus Kopka, Jens Pietzsch
Theranostics 2024; 14(14): 5371-5387. doi:10.7150/thno.100091
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Lutetium-177-PSMA therapy for recurrent/metastatic salivary gland cancer: a prospective pilot study
Niels J. van Ruitenbeek, Maike J.M. Uijen, Chantal M.L. Driessen, Steffie M.B. Peters, Bastiaan M. Privé, Adriana C.H. van Engen-van Grunsven, Mark W. Konijnenberg, Martin Gotthardt, James Nagarajah, Carla M.L. van Herpen
Theranostics 2024; 14(14): 5388-5399. doi:10.7150/thno.99035
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Theranostics with somatostatin receptor antagonists in SCLC: Correlation of 68Ga-SSO120 PET with immunohistochemistry and survival
Ilektra Antonia Mavroeidi, Anna Romanowicz, Tristan Haake, Johannes Wienker, Martin Metzenmacher, Kaid Darwiche, Filiz Oezkan, Servet Bölükbas, Martin Stuschke, Lale Umutlu, Marcel Opitz, Michael Nader, Rainer Hamacher, Jens Siveke, Jane Winantea, Wolfgang P. Fendler, Marcel Wiesweg, Wilfried E. E. Eberhardt, Ken Herrmann, Dirk Theegarten, Martin Schuler, Hubertus Hautzel, David Kersting
Theranostics 2024; 14(14): 5400-5412. doi:10.7150/thno.98819
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Graphic abstract

Milk-derived extracellular vesicles enable gut-to-tumor oral delivery of tumor-activated doxorubicin prodrugs
Hochung Jang, Jiwoong Choi, Daeho Park, Geonhee Han, Eun Hye Kim, Kwangmeyung Kim, Sun Hwa Kim, Man Kyu Shim, Yoosoo Yang
Theranostics 2024; 14(14): 5413-5428. doi:10.7150/thno.97269
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Graphic abstract

Clearance of senescent cells enhances skin wound healing in type 2 diabetic mice
Priyadarshani Nadeeshika Samarawickrama, Guiqin Zhang, Enfang Zhu, Xin Dong, Ayesha Nisar, Hong Zhu, Yuan Ma, Zheyan Zhou, Honglin Yang, Li Gui, Mei Cao, Wei Li, Yu Chang, Meiting Zi, Haoling Cui, Zhongping Duan, Xuan Zhang, Wen Li, Yonghan He
Theranostics 2024; 14(14): 5429-5442. doi:10.7150/thno.100991
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Honokiol enhances the sensitivity of cetuximab in KRASG13D mutant colorectal cancer through destroying SNX3-retromer complex
Qianru Zhu, Ruonan Zhang, Xiaoqing Gu, Ziming Zhao, Quan Gao, Min Chen, Qibiao Wu, Tian Xie, Xinbing Sui
Theranostics 2024; 14(14): 5443-5460. doi:10.7150/thno.97180
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Mesenchymal stem cell-derived extracellular vesicles targeting irradiated intestine exert therapeutic effects
Ningning He, Mingxin Dong, Yuxiao Sun, Mengmeng Yang, Yan Wang, Liqing Du, Kaihua Ji, Jinhan Wang, Manman Zhang, Yeqing Gu, Xinran Lu, Yang Liu, Qin Wang, Zongjin Li, Huijuan Song, Chang Xu, Qiang Liu
Theranostics 2024; 14(14): 5492-5511. doi:10.7150/thno.97623
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Hypoxia inducible factor (HIF) 3α prevents COPD by inhibiting alveolar epithelial cell ferroptosis via the HIF-3α-GPx4 axis
Junchao Jiang, Zhoude Zheng, Shengsong Chen, Jixiang Liu, Ju Jia, Yuhang Huang, Qing Liu, Chung Y Cheung, Don D Sin, Ting Yang, Chen Wang
Theranostics 2024; 14(14): 5512-5527. doi:10.7150/thno.99237
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Graphic abstract

The m6A reader YTHDC2 promotes the pathophysiology of temporal lobe epilepsy by modulating SLC7A11-dependent glutamate dysregulation in astrocytes
Kai Zhang, Zhiquan Yang, Zhuanyi Yang, Liangchao Du, Yu Zhou, Shiyu Fu, Xiaoyue Wang, Xing Li, Dingyang Liu, Xinghui He
Theranostics 2024; 14(14): 5551-5570. doi:10.7150/thno.100703
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Graphic abstract

pH and H2O2 dual-sensitive nanoparticles enable enhanced and safe glucose-responsive oral insulin delivery for diabetes mellitus treatment
Muzi Li, Nan Wang, Ruiyuan Liu, Xinyue Zhang, Wei He, Wen Zhang, Jiaxin Li, Chen Peng, Yan Li
Theranostics 2024; 14(14): 5596-5607. doi:10.7150/thno.98177
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Mild-photothermal and nanocatalytic therapy for obesity and associated diseases
Lewen Zheng, Aung Than, Ping Zan, Dongsheng Li, Zheye Zhang, Melvin Khee Shing Leow, Peng Chen
Theranostics 2024; 14(14): 5608-5620. doi:10.7150/thno.99948
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Conditional ablation of DIS3L2 ribonuclease in pre-meiotic germ cells causes defective spermatogenesis and infertility in male mice
Nana Li, Junjie Yu, Yan-Qin Feng, Phoebe Xu, Xiao Wang, Meiyang Zhou, Hong Li, Yu Xu, Zhengpin Wang
Theranostics 2024; 14(14): 5621-5642. doi:10.7150/thno.98620
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Engineered plant-derived extracellular vesicles for targeted regulation and treatment of colitis-associated inflammation
Su Jin Kang, Jeong Hyun Lee, Won Jong Rhee
Theranostics 2024; 14(14): 5643-5661. doi:10.7150/thno.97139
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MCT1-mediated endothelial cell lactate shuttle as a target for promoting axon regeneration after spinal cord injury
Chaoran Shi, Jiaqi Xu, Yinghe Ding, Xingyi Chen, Feifei Yuan, Fengzhang Zhu, Chunyue Duan, Jianzhong Hu, Hongbin Lu, Tianding Wu, Liyuan Jiang
Theranostics 2024; 14(14): 5662-5681. doi:10.7150/thno.96374
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Maternal immune activation upregulates the AU020206-IRFs-STAT1 axis in modulating cytokine production in the brain
Jing Yang, Wenjun Yu, Runmiao Zhu, Shuangyan Li, Yue Gao, Jinfa Chen, Bin Zhang, Wanshan Wang, Xinping Yang
Theranostics 2024; 14(14): 5682-5697. doi:10.7150/thno.96110
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Dual role of exosomal circCMTM3 derived from GSCs in impeding degradation and promoting phosphorylation of STAT5A to facilitate vasculogenic mimicry formation in glioblastoma
Chengbin Wang, Yingliang Liu, Zhenxing Zuo, Daming Cui, Yuzhen Xu, Li Li, Yang Jiang
Theranostics 2024; 14(14): 5698-5724. doi:10.7150/thno.97057
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Reviews

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Nanotechnology based gas delivery system: a “green” strategy for cancer diagnosis and treatment
Meixu Chen, Tianyue Xu, Linlin Song, Ting Sun, Zihan Xu, Yujie Zhao, Peixin Du, Ling Xiong, Zhankun Yang, Jing Jing, Hubing Shi
Theranostics 2024; 14(14): 5461-5491. doi:10.7150/thno.98884
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Advances in targeted delivery of mRNA into immune cells for enhanced cancer therapy
Linzhuo Huang, Zhiquan Huang, Yuxuan Zhang, Chunhao Lin, Zixuan Zhao, Rong Li, Phei Er Saw, Xiaoding Xu
Theranostics 2024; 14(14): 5528-5550. doi:10.7150/thno.93745
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Microenvironment-responsive nanosystems for ischemic stroke therapy
Fang Wu, Zhijian Zhang, Shengnan Ma, Yanyan He, Yuxi He, Lixia Ma, Ningjing Lei, Wenjing Deng, Fazhan Wang
Theranostics 2024; 14(14): 5571-5595. doi:10.7150/thno.99822
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Empowering brain tumor management: chimeric antigen receptor macrophage therapy
Fan Feng, Jianyu Shen, Qichao Qi, Yulin Zhang, Shilei Ni
Theranostics 2024; 14(14): 5725-5742. doi:10.7150/thno.98290
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Erratum

Adipocytes fuel gastric cancer omental metastasis via PITPNC1-mediated fatty acid metabolic reprogramming: Erratum
Yujing Tan, Kelin Lin, Yang Zhao, Qijing Wu, Dongping Chen, Jin Wang, Yanxiao Liang, Jingyu Li, Jiazhu Hu, Hao Wang, Yajing Liu, Shuyi Zhang, Wanming He, Qiong Huang, Xingbin Hu, Zhiqi Yao, Bishan Liang, Wangjun Liao, Min Shi
Theranostics 2024; 14(14): 5743-5744. doi:10.7150/thno.101689
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