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Volume 13 (3); 2023

Research Papers

NQO1 regulates cell cycle progression at the G2/M phase
Eun-Taex Oh, Ha Gyeong Kim, Chul Hoon Kim, Jeonghun Lee, Chulhee Kim, Jae-Seon Lee, Yunmi Cho, Heon Joo Park
Theranostics 2023; 13(3): 873-895. doi:10.7150/thno.77444
Abstract Full text PDF PubMed PMC

TCRαβ⁺NK1.1^-CD4^-CD8^- double-negative T cells inhibit central and peripheral inflammation and ameliorate ischemic stroke in mice
Dan Tian, Yuhualei Pan, Yushang Zhao, Huan Wang, Yue Tian, Lu Yang, Wen Shi, Chengjie Zhang, Yanbing Zhu, Yongbo Zhang, Songlin Wang, Dong Zhang
Theranostics 2023; 13(3): 896-909. doi:10.7150/thno.80307
Abstract Full text PDF PubMed PMC

Photobiomodulation attenuates oligodendrocyte dysfunction and prevents adverse neurological consequences in a rat model of early life adversity
Zhihai Huang, Yulan Zhang, Xiaohui Ma, Yu Feng, Xuemei Zong, J. Dedrick Jordan, Quanguang Zhang
Theranostics 2023; 13(3): 913-930. doi:10.7150/thno.78777
Abstract Full text PDF PubMed PMC

Phloretin decreases microglia-mediated synaptic engulfment to prevent chronic mild stress-induced depression-like behaviors in the mPFC
Chenchen Li, Bo Liu, Jingyi Xu, Bin Jing, Lijie Guo, Liyong Wang, Milin Wang, Haochen Zhang, Qianqian He, Xin Yu, Yan Zhang, Zhi-Qing David Xu, Yutao Yang
Theranostics 2023; 13(3): 955-972. doi:10.7150/thno.76553
Abstract Full text PDF PubMed PMC

Dynamic SUMOylation of MORC2 orchestrates chromatin remodelling and DNA repair in response to DNA damage and drives chemoresistance in breast cancer
Fang-Lin Zhang, Shao-Ying Yang, Li Liao, Tai-Mei Zhang, Yin-Ling Zhang, Shu-Yuan Hu, Ling Deng, Min-Ying Huang, Lisa Andriani, Xiao-Yan Ma, Zhi-Min Shao, Da-Qiang Li
Theranostics 2023; 13(3): 973-990. doi:10.7150/thno.79688
Abstract Full text PDF PubMed PMC

Exosomal STIMATE derived from type II alveolar epithelial cells controls metabolic reprogramming of tissue-resident alveolar macrophages
Zunyong Feng, Zhou Jing, Qiang Li, Liuxi Chu, YuXin Jiang, Xuanbo Zhang, Liang Yan, Yinhua Liu, Jing Jiang, Ping Xu, Qun Chen, Ming Wang, Hui Yang, Guoren Zhou, Xiaochun Jiang, Xiaoyuan Chen, Hongping Xia
Theranostics 2023; 13(3): 991-1009. doi:10.7150/thno.82552
Abstract Full text PDF PubMed PMC

Ultrasmall PtAu₂ nanoclusters activate endogenous anti-inflammatory and anti-oxidative systems to prevent inflammatory osteolysis
Xuzhuo Chen, Xiankun Cao, Dasheng Zheng, Chang Li, Yan Chen, Keyu Kong, Weifeng Xu, Bin Shi, Xinwei Chen, Fengrong Dai, Shanyong Zhang
Theranostics 2023; 13(3): 1010-1027. doi:10.7150/thno.80514
Abstract Full text PDF PubMed PMC

Low-dose X-ray radiodynamic therapy solely based on gold nanoclusters for efficient treatment of deep hypoxic solid tumors combined with enhanced antitumor immune response
Shengcang Zhu, Feihong Yan, Lulu Yang, Bingyi Li, Ruxian Xue, Wenwen Yu, Yu Wang, Lu Huang, Lijun Wang, Rongcheng Han, Yuqiang Jiang
Theranostics 2023; 13(3): 1042-1058. doi:10.7150/thno.78649
Abstract Full text PDF PubMed PMC

Hyperactive neuronal autophagy depletes BDNF and impairs adult hippocampal neurogenesis in a corticosterone-induced mouse model of depression
Kuo Zhang, Fan Wang, Mengying Zhai, Meiyao He, Yuxuan Hu, Lijin Feng, Yuting Li, Jingyu Yang, Chunfu Wu
Theranostics 2023; 13(3): 1059-1075. doi:10.7150/thno.81067
Abstract Full text PDF PubMed PMC

Hepatic PTP4A1 ameliorates high-fat diet-induced hepatosteatosis and hyperglycemia by the activation of the CREBH/FGF21 axis
Byungtae Hwang, Min-Gi Kwon, Min Ji Cho, Nam-Kyung Lee, Jangwook Lee, Jeong Woong Lee, Kyoung-Jin Oh, Kwang-Hee Bae, Jung Hwan Hwang, Jeong-Ki Min, Jong-Gil Park
Theranostics 2023; 13(3): 1076-1090. doi:10.7150/thno.79434
Abstract Full text PDF PubMed PMC

Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair
Diane Bruyere, Patrick Roncarati, Alizee Lebeau, Thomas Lerho, Florian Poulain, Elodie Hendrick, Charlotte Pilard, Celia Reynders, Marie Ancion, Margaux Luyckx, Michael Renard, Yves Jacob, Jean-Claude Twizere, Raphael Peiffer, Olivier Peulen, Philippe Delvenne, Pascale Hubert, Alison McBride, Nicolas Gillet, Murielle Masson, Michael Herfs
Theranostics 2023; 13(3): 1130-1149. doi:10.7150/thno.78091
Abstract Full text PDF PubMed PMC

Combined use of magnetic microbeads for endothelial cell isolation and enhanced cell engraftment in myocardial repair
Christian Biederbick, Jan C. Heinemann, Sarah Rieck, Florian Winkler, Annika Ottersbach, Miriam Schiffer, Georg D. Duerr, Dietmar Eberbeck, Michael Hesse, Wilhelm Röll, Daniela Wenzel
Theranostics 2023; 13(3): 1150-1164. doi:10.7150/thno.75871
Abstract Full text PDF PubMed PMC

Colonization with two different Blastocystis subtypes in DSS-induced colitis mice is associated with strikingly different microbiome and pathological features
Lei Deng, Lukasz Wojciech, Chin Wen Png, Dorinda Yan Qin Kioh, Yuxiang Gu, Thet Tun Aung, Benoit Malleret, Eric Chun Yong Chan, Guangneng Peng, Yongliang Zhang, Nicholas Robert John Gascoigne, Kevin Shyong Wei Tan
Theranostics 2023; 13(3): 1165-1179. doi:10.7150/thno.81583
Abstract Full text PDF PubMed PMC

Using a novel rapid alternating steering angles pulse sequence to evaluate the impact of theranostic ultrasound-mediated ultra-short pulse length on blood-brain barrier opening volume and closure, cavitation mapping, drug delivery feasibility, and safety
Alec J. Batts, Robin Ji, Rebecca L. Noel, Alina R. Kline-Schoder, Sua Bae, Nancy Kwon, Elisa E. Konofagou
Theranostics 2023; 13(3): 1180-1197. doi:10.7150/thno.76199
Abstract Full text PDF PubMed PMC

PLK1-mediated phosphorylation of β-catenin enhances its stability and transcriptional activity for extracellular matrix remodeling in metastatic NSCLC
Da-Eun Kim, Sol-Bi Shin, Chang-Hyeon Kim, Yeo-Bin Kim, Hyun-Ji Oh, Hyungshin Yim
Theranostics 2023; 13(3): 1198-1216. doi:10.7150/thno.79318
Abstract Full text PDF PubMed PMC

Reviews

Targeted and responsive biomaterials in osteoarthritis
Jiadong Li, Hao Zhang, Yafei Han, Yan Hu, Zhen Geng, Jiacan Su
Theranostics 2023; 13(3): 931-954. doi:10.7150/thno.78639
Abstract Full text PDF PubMed PMC

When three is not a crowd: trispecific antibodies for enhanced cancer immunotherapy
Antonio Tapia-Galisteo, Marta Compte, Luis Álvarez-Vallina, Laura Sanz
Theranostics 2023; 13(3): 1028-1041. doi:10.7150/thno.81494
Abstract Full text PDF PubMed PMC

Saliva-based microfluidic point-of-care diagnostic
Trey W. Pittman, Daniel Balazs Decsi, Chamindie Punyadeera, Charles S. Henry
Theranostics 2023; 13(3): 1091-1108. doi:10.7150/thno.78872
Abstract Full text PDF PubMed PMC

Exploring neurotransmitters and their receptors for breast cancer prevention and treatment
Ruo Qi Li, Xiao Hong Zhao, Qin Zhu, Tao Liu, Hubert Hondermarck, Rick F. Thorne, Xu Dong Zhang, Jin Nan Gao
Theranostics 2023; 13(3): 1109-1129. doi:10.7150/thno.81403
Abstract Full text PDF PubMed PMC

Erratum

Hypoxia-induced up-regulation of VASP promotes invasiveness and metastasis of hepatocellular carcinoma: Erratum
Zhikui Liu, Yufeng Wang, Changwei Dou, Meng Xu, Liankang Sun, Liang Wang, Bowen Yao, Qing Li, Wei Yang, Kangsheng Tu, Qingguang Liu
Theranostics 2023; 13(3): 910-912. doi:10.7150/thno.79069
Abstract Full text PDF PubMed PMC

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