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Volume 8 (5); 2018

Research Paper

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Systematic Assessment of Strategies for Lung-targeted Delivery of MicroRNA Mimics
Kenny Schlosser, Mohamad Taha, Duncan J. Stewart
Theranostics 2018; 8(5): 1213-1226. doi:10.7150/thno.22912
[Abstract] [Full text] [PDF]


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Serum exosomes can restore cellular function in vitro and be used for diagnosis in dysferlinopathy
Xue Dong, Xianjun Gao, Yi Dai, Ning Ran, HaiFang Yin
Theranostics 2018; 8(5): 1243-1255. doi:10.7150/thno.22856
[Abstract] [Full text] [PDF]


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A low microRNA-630 expression confers resistance to tyrosine kinase inhibitors in EGFR-mutated lung adenocarcinomas via miR-630/YAP1/ERK feedback loop
De-Wei Wu, Yao-Chen Wang, Lee Wang, Chih Yi Chen, Huei Lee
Theranostics 2018; 8(5): 1256-1269. doi:10.7150/thno.22048
[Abstract] [Full text] [PDF]


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GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade
Mingo Ming-Ho Yung, Hermit Wai-Man Tang, Patty Chun-Hui Cai, Thomas Ho-Yin Leung, Siew-Fei Ngu, Karen Kar-Loen Chan, Dakang Xu, Huijuan Yang, Hextan Yuen-Sheung Ngan, David Wai Chan
Theranostics 2018; 8(5): 1270-1285. doi:10.7150/thno.22536
[Abstract] [Full text] [PDF]


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S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer
Yumei Huang, Kaishun Hu, Sheng Zhang, Xiaorong Dong, Zhongyuan Yin, Rui Meng, Yingchao Zhao, Xiaofang Dai, Tao Zhang, Kunyu Yang, Li Liu, Kai Huang, Shaojun Shi, Yu Zhang, Junjie Chen, Gang Wu, Shuangbing Xu
Theranostics 2018; 8(5): 1286-1300. doi:10.7150/thno.22552
[Abstract] [Full text] [PDF]


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Non-invasive Prenatal Diagnosis of Chromosomal Aneuploidies and Microdeletion Syndrome Using Fetal Nucleated Red Blood Cells Isolated by Nanostructure Microchips
Chun Feng, Zhaobo He, Bo Cai, Jianhong Peng, Jieping Song, Xuechen Yu, Yue Sun, Jing Yuan, Xingzhong Zhao, Yuanzhen Zhang
Theranostics 2018; 8(5): 1301-1311. doi:10.7150/thno.21979
[Abstract] [Full text] [PDF]


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Pharmacological Ascorbate Suppresses Growth of Gastric Cancer Cells with GLUT1 Overexpression and Enhances the Efficacy of Oxaliplatin Through Redox Modulation
Yun-Xin Lu, Qi-Nian Wu, Dong-liang Chen, Le-Zong Chen, Zi-Xian Wang, Chao Ren, Hai-yu Mo, Ya Chen, Hui Sheng, Ying-Nan Wang, Yun Wang, Jia-Huan Lu, De-shen Wang, Zhao-lei Zeng, Feng Wang, Feng-Hua Wang, Yu-Hong Li, Huai-Qiang Ju, Rui-Hua Xu
Theranostics 2018; 8(5): 1312-1326. doi:10.7150/thno.21745
[Abstract] [Full text] [PDF]


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Drug Release from Phase-Changeable Nanodroplets Triggered by Low-Intensity Focused Ultrasound
Yang Cao, Yuli Chen, Tao Yu, Yuan Guo, Fengqiu Liu, Yuanzhi Yao, Pan Li, Dong Wang, Zhigang Wang, Yu Chen, Haitao Ran
Theranostics 2018; 8(5): 1327-1339. doi:10.7150/thno.21492
[Abstract] [Full text] [PDF]


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Desmin- and vimentin-mediated hepatic stellate cell-targeting radiotracer 99mTc-GlcNAc-PEI for liver fibrosis imaging with SPECT
Deliang Zhang, Rongqiang Zhuang, Zhide Guo, Mengna Gao, Lumei Huang, Linyi You, Pu Zhang, Jindian Li, Xinhui Su, Hua Wu, Xiaoyuan Chen, Xianzhong Zhang
Theranostics 2018; 8(5): 1340-1349. doi:10.7150/thno.22806
[Abstract] [Full text] [PDF]


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Targeting Tumor Hypoxia Using Nanoparticle-engineered CXCR4-overexpressing Adipose-derived Stem Cells
Xinyi Jiang, Christine Wang, Sergio Fitch, Fan Yang
Theranostics 2018; 8(5): 1350-1360. doi:10.7150/thno.22736
[Abstract] [Full text] [PDF]


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Sarcoma-Targeting Peptide-Decorated Polypeptide Nanogel Intracellularly Delivers Shikonin for Upregulated Osteosarcoma Necroptosis and Diminished Pulmonary Metastasis
Suoyuan Li, Tao Zhang, Weiguo Xu, Jianxun Ding, Fei Yin, Jing Xu, Wei Sun, Hongsheng Wang, Mengxiong Sun, Zhengdong Cai, Yingqi Hua
Theranostics 2018; 8(5): 1361-1375. doi:10.7150/thno.18299
[Abstract] [Full text] [PDF]


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Cancer-associated fibroblasts enhance tumor 18F-FDG uptake and contribute to the intratumor heterogeneity of PET-CT
Chengfang Shangguan, Guifang Gan, Jieying Zhang, Jinliang Wu, Ying Miao, Miao Zhang, Biao Li, Jun Mi
Theranostics 2018; 8(5): 1376-1388. doi:10.7150/thno.22717
[Abstract] [Full text] [PDF]


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Longitudinal Multiplexed Measurement of Quantitative Proteomic Signatures in Mouse Lymphoma Models Using Magneto-Nanosensors
Jung-Rok Lee, Iris Appelmann, Cornelius Miething, Tyler O. Shultz, Daniel Ruderman, Dokyoon Kim, Parag Mallick, Scott W. Lowe, Shan X. Wang
Theranostics 2018; 8(5): 1389-1398. doi:10.7150/thno.20706
[Abstract] [Full text] [PDF]


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Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis
Stella Cosenza, Karine Toupet, Marie Maumus, Patricia Luz-Crawford, Olivier Blanc-Brude, Christian Jorgensen, Danièle Noël
Theranostics 2018; 8(5): 1399-1410. doi:10.7150/thno.21072
[Abstract] [Full text] [PDF]


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Naphthalene-based fluorescent probes for glutathione and their applications in living cells and patients with sepsis
Jun Li, Younghee Kwon, Kyung Soo Chung, Chang Su Lim, Dayoung Lee, Yongkang Yue, Jisoo Yoon, Gyoungmi Kim, Sang-Jip Nam, Youn Wokk Chung, Hwan Myung Kim, Caixia Yin, Ji-Hwan Ryu, Juyoung Yoon
Theranostics 2018; 8(5): 1411-1420. doi:10.7150/thno.22252
[Abstract] [Full text] [PDF]


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Selection of Tissue Factor-Deficient Cell Transplants as a Novel Strategy for Improving Hemocompatibility of Human Bone Marrow Stromal Cells
Michaela Oeller, Sandra Laner-Plamberger, Sarah Hochmann, Nina Ketterl, Martina Feichtner, Gabriele Brachtl, Anna Hochreiter, Cornelia Scharler, Lara Bieler, Pasquale Romanelli, Sebastien Couillard-Despres, Elisabeth Russe, Katharina Schallmoser, Dirk Strunk
Theranostics 2018; 8(5): 1421-1434. doi:10.7150/thno.21906
[Abstract] [Full text] [PDF]


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Targeted Delivery of Functionalized Upconversion Nanoparticles for Externally Triggered Photothermal/Photodynamic Therapies of Brain Glioblastoma
Yuan-Chung Tsai, Priya Vijayaraghavan, Wen-Hsuan Chiang, Hsin-Hung Chen, Te-I Liu, Ming-Yin Shen, Ayumu Omoto, Masao Kamimura, Kohei Soga, Hsin-Cheng Chiu
Theranostics 2018; 8(5): 1435-1448. doi:10.7150/thno.22482
[Abstract] [Full text] [PDF]


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D-alanyl-D-alanine-Modified Gold Nanoparticles Form a Broad-Spectrum Sensor for Bacteria
Xinglong Yang, Yan Dang, Jinli Lou, Huawu Shao, Xingyu Jiang
Theranostics 2018; 8(5): 1449-1457. doi:10.7150/thno.22540
[Abstract] [Full text] [PDF]

Review

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Molecular Magnetic Resonance Imaging of Endothelial Activation in the Central Nervous System
Maxime Gauberti, Antoine P. Fournier, Fabian Docagne, Denis Vivien, Sara Martinez de Lizarrondo
Theranostics 2018; 8(5): 1195-1212. doi:10.7150/thno.22662
[Abstract] [Full text] [PDF]


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Indocyanine green-incorporating nanoparticles for cancer theranostics
Haolu Wang, Xinxing Li, Brian Wan-Chi Tse, Haotian Yang, Camilla A. Thorling, Yuxin Liu, Margaux Touraud, Jean Batiste Chouane, Xin Liu, Michael S. Roberts, Xiaowen Liang
Theranostics 2018; 8(5): 1227-1242. doi:10.7150/thno.22872
[Abstract] [Full text] [PDF]