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Volume 8 (6); 2018

Research Paper

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Potential Red-Flag Identification of Colorectal Adenomas with Wide-Field Fluorescence Molecular Endoscopy
Elmire Hartmans, Jolien J.J. Tjalma, Matthijs D. Linssen, Pilar Beatriz Garcia Allende, Marjory Koller, Annelies Jorritsma-Smit, Mariana e Silva de Oliveira Nery, Sjoerd G. Elias, Arend Karrenbeld, Elisabeth G.E. de Vries, Jan H. Kleibeuker, Gooitzen M. van Dam, Dominic J. Robinson, Vasilis Ntziachristos, Wouter B. Nagengast
Theranostics 2018; 8(6): 1458-1467. doi:10.7150/thno.22033
[Abstract] [Full text] [PDF]


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Urinary Metabolites Associated with Blood Pressure on a Low- or High-Sodium Diet
Yuan Cheng, Haiying Song, Xiaoqing Pan, Hong Xue, Yifei Wan, Tao Wang, Zhongmin Tian, Entai Hou, Ian R. Lanza, Pengyuan Liu, Yong Liu, Purushottam W. Laud, Kristie Usa, Yongcheng He, Mingyu Liang
Theranostics 2018; 8(6): 1468-1480. doi:10.7150/thno.22018
[Abstract] [Full text] [PDF]


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XIAP Limits Autophagic Degradation of Sox2 and Is A Therapeutic Target in Nasopharyngeal Carcinoma Stem Cells
Jiao Ji, Yan Yu, Zhi-Ling Li, Ming-Yuan Chen, Rong Deng, Xiang Huang, Guang-Feng Wang, Meng-Xia Zhang, Qi Yang, Senthilkumar Ravichandran, Gong-Kan Feng, Xue-Lian Xu, Chen-Lu Yang, Miao-Zhen Qiu, Lin Jiao, Dajun Yang, Xiao-Feng Zhu
Theranostics 2018; 8(6): 1494-1510. doi:10.7150/thno.21717
[Abstract] [Full text] [PDF]


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Elevated Expression of miR302-367 in Endothelial Cells Inhibits Developmental Angiogenesis via CDC42/CCND1 Mediated Signaling Pathways
Jingjiang Pi, Jie Liu, Tao Zhuang, Lin Zhang, Huimin Sun, Xiaoli Chen, Qian Zhao, Yashu Kuang, Sheng Peng, Xiaohui Zhou, Zuoren Yu, Ting Tao, Brian Tomlinson, Paul Chan, Ying Tian, Huimin Fan, Zhongmin Liu, Xiangjian Zheng, Edward Morrisey, Yuzhen Zhang
Theranostics 2018; 8(6): 1511-1526. doi:10.7150/thno.21986
[Abstract] [Full text] [PDF]


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PRL-3 is a potential glioblastoma prognostic marker and promotes glioblastoma progression by enhancing MMP7 through the ERK and JNK pathways
Nan Mu, Jintao Gu, Nannan Liu, Xiaochang Xue, Zhen Shu, Kuo Zhang, Tonglie Huang, Chu Chu, Wangqian Zhang, Li Gong, Huadong Zhao, Bo Jia, Dakuan Gao, Lei Shang, Wei Zhang, Qingdong Guo
Theranostics 2018; 8(6): 1527-1539. doi:10.7150/thno.22699
[Abstract] [Full text] [PDF]


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The role of PTRF/Cavin1 as a biomarker in both glioma and serum exosomes
Kai Huang, Chuan Fang, Kaikai Yi, Xing Liu, Hongzhao Qi, Yanli Tan, Junhu Zhou, Ying Li, Mingyang Liu, Yuqing Zhang, Jingxuan Yang, Jianning Zhang, Min Li, Chunsheng Kang
Theranostics 2018; 8(6): 1540-1557. doi:10.7150/thno.22952
[Abstract] [Full text] [PDF]


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Oxygen-generating Hybrid Polymeric Nanoparticles with Encapsulated Doxorubicin and Chlorin e6 for Trimodal Imaging-Guided Combined Chemo-Photodynamic Therapy
DanRong Hu, LiJuan Chen, Ying Qu, JinRong Peng, BingYang Chu, Kun Shi, Ying Hao, Lin Zhong, MengYao Wang, ZhiYong Qian
Theranostics 2018; 8(6): 1558-1574. doi:10.7150/thno.22989
[Abstract] [Full text] [PDF]


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Receptor-targeted aptamer-siRNA conjugate-directed transcriptional regulation of HIV-1
Jiehua Zhou, Daniel Lazar, Haitang Li, Xin Xia, Sangeetha Satheesan, Paige Charlins, Denis O'Mealy, Ramesh Akkina, Sheena Saayman, Marc S. Weinberg, John J. Rossi, Kevin V. Morris
Theranostics 2018; 8(6): 1575-1590. doi:10.7150/thno.23085
[Abstract] [Full text] [PDF]


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Bioinspired Multifunctional Melanin-Based Nanoliposome for Photoacoustic/Magnetic Resonance Imaging-Guided Efficient Photothermal Ablation of Cancer
Liang Zhang, Danli Sheng, Dong Wang, Yuanzhi Yao, Ke Yang, Zhigang Wang, Liming Deng, Yu Chen
Theranostics 2018; 8(6): 1591-1606. doi:10.7150/thno.22430
[Abstract] [Full text] [PDF]


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Exosomal DMBT1 from human urine-derived stem cells facilitates diabetic wound repair by promoting angiogenesis
Chun-Yuan Chen, Shan-Shan Rao, Lu Ren, Xiong-Ke Hu, Yi-Juan Tan, Yin Hu, Juan Luo, Yi-Wei Liu, Hao Yin, Jie Huang, Jia Cao, Zhen-Xing Wang, Zheng-Zhao Liu, Hao-Ming Liu, Si-Yuan Tang, Ran Xu, Hui Xie
Theranostics 2018; 8(6): 1607-1623. doi:10.7150/thno.22958
[Abstract] [Full text] [PDF]


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Gelatin Nanoparticle-Coated Silicon Beads for Density-Selective Capture and Release of Heterogeneous Circulating Tumor Cells with High Purity
Qinqin Huang, Fu-Bing Wang, Chun-Hui Yuan, Zhaobo He, Lang Rao, Bo Cai, Bolei Chen, Susu Jiang, Zhiqiang Li, Jincao Chen, Wei Liu, Feng Guo, Zheng Ao, Shi Chen, Xing-Zhong Zhao
Theranostics 2018; 8(6): 1624-1635. doi:10.7150/thno.23531
[Abstract] [Full text] [PDF]


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Non-Invasive Electrical Impedance Tomography for Multi-Scale Detection of Liver Fat Content
Yuan Luo, Parinaz Abiri, Shell Zhang, Chih-Chiang Chang, Amir H. Kaboodrangi, Rongsong Li, Alex Bui, Rajesh Kumar, Mary Woo, Zhaoping Li, René R. Sevag Packard, Yu-Chong Tai, Tzung K. Hsiai
Theranostics 2018; 8(6): 1636-1647. doi:10.7150/thno.22233
[Abstract] [Full text] [PDF]


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2D Superparamagnetic Tantalum Carbide Composite MXenes for Efficient Breast-Cancer Theranostics
Zhuang Liu, Han Lin, Menglong Zhao, Chen Dai, Shengjian Zhang, Weijun Peng, Yu Chen
Theranostics 2018; 8(6): 1648-1664. doi:10.7150/thno.23369
[Abstract] [Full text] [PDF]


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Porphyrin-grafted Lipid Microbubbles for the Enhanced Efficacy of Photodynamic Therapy in Prostate Cancer through Ultrasound-controlled In Situ Accumulation
Yujia You, Xiaolong Liang, Tinghui Yin, Min Chen, Chen Qiu, Chuang Gao, Xiaoyou Wang, Yongjiang Mao, Enze Qu, Zhifei Dai, Rongqin Zheng
Theranostics 2018; 8(6): 1665-1677. doi:10.7150/thno.22469
[Abstract] [Full text] [PDF]


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Surface Enhanced Raman Spectroscopy (SERS) for the Multiplex Detection of Braf, Kras, and Pik3ca Mutations in Plasma of Colorectal Cancer Patients
Xiaozhou Li, Tianyue Yang, Caesar Siqi Li, Youtao Song, Hong Lou, Dagang Guan, Lili Jin
Theranostics 2018; 8(6): 1678-1689. doi:10.7150/thno.22502
[Abstract] [Full text] [PDF]


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E. coli Nissle 1917-Derived Minicells for Targeted Delivery of Chemotherapeutic Drug to Hypoxic Regions for Cancer Therapy
Yunlei Zhang, Wei Ji, Lian He, Yiyan Chen, Xuezhi Ding, Yunjun Sun, Shengbiao Hu, Huijun Yang, Weitao Huang, Youming Zhang, Fei Liu, Liqiu Xia
Theranostics 2018; 8(6): 1690-1705. doi:10.7150/thno.21575
[Abstract] [Full text] [PDF]


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Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) Magnetic Resonance Metabolic Imaging Identifies the Penumbra Following Acute Ischemic Stroke
Graeme A Deuchar, David Brennan, William M Holmes, Martin Shaw, I Mhairi Macrae, Celestine Santosh
Theranostics 2018; 8(6): 1706-1722. doi:10.7150/thno.21685
[Abstract] [Full text] [PDF]


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The enhanced antitumor-specific immune response with mannose- and CpG-ODN-coated liposomes delivering TRP2 peptide
Chunhui Lai, Siliang Duan, Fang Ye, Xiaoqiong Hou, Xi Li, Jin Zhao, Xia Yu, Zixi Hu, Zhuoran Tang, Fengzhen Mo, Xiaomei Yang, Xiaoling Lu
Theranostics 2018; 8(6): 1723-1739. doi:10.7150/thno.22056
[Abstract] [Full text] [PDF]


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Genomic analysis of liver cancer unveils novel driver genes and distinct prognostic features
Xiangchun Li, Weiqi Xu, Wei Kang, Sunny H. Wong, Mengyao Wang, Yong Zhou, Xiaodong Fang, Xiuqing Zhang, Huanming Yang, Chi H. Wong, Ka F. To, Stephen L. Chan, Matthew T.V. Chan, Joseph J.Y. Sung, William K.K. Wu, Jun Yu
Theranostics 2018; 8(6): 1740-1751. doi:10.7150/thno.22010
[Abstract] [Full text] [PDF]

Review

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Current Strategies for Brain Drug Delivery
Xiaowei Dong
Theranostics 2018; 8(6): 1481-1493. doi:10.7150/thno.21254
[Abstract] [Full text] [PDF]