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Volume 15 (6); 2025

Research Papers

Collagen-targeted PET imaging for progressive experimental lung fibrosis quantification and monitoring of efficacy of anti-fibrotic therapies
Alexandre Magno Maneschy Dias, Olivier Burgy, Mathieu Moreau, Victor Goncalves, Lenny Pommerolle, Romain Douhard, Alan Courteau, Alex Helbling, Mélanie Guillemin, John Simonet, Alexandra Oudot, Carmen Garrido, Philippe Bonniaud, Françoise Goirand, Bertrand Collin, Pierre-Simon Bellaye
Theranostics 2025; 15(6): 2092-2103. doi:10.7150/thno.106367
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OASL promotes immune evasion in pancreatic ductal adenocarcinoma by enhancing autolysosome-mediated degradation of MHC-I
Xin Xing, Xia-Qing Li, Shi-Qi Yin, Hong-Tai Ma, Shu-Yu Xiao, Aziguli Tulamaiti, Yan Yang, Shu-Heng Jiang, Li-Peng Hu, Zhi-Gang Zhang, Yan-Miao Huo, Dong-Xue Li, Xiao-Mei Yang, Xue-Li Zhang
Theranostics 2025; 15(6): 2104-2120. doi:10.7150/thno.103494
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OTUD7B is a new deubiquitinase targeting p53
Caoyuan Ding, Leixi Cao, Ruijie Wang, Qichen Wu, Mengfan Li, Jinjing Zhang, Rick F. Thorne, Jinming Li, Jianli Ma, Mian Wu, Shundong Cang
Theranostics 2025; 15(6): 2121-2138. doi:10.7150/thno.103012
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Microalgae-based bacteria for oral treatment of ASD through enhanced intestinal colonization and homeostasis
Rongrong Yang, Li Ma, Huan Peng, Yifang Zhai, Gengyao Zhou, Linjuan Zhang, Lixia Zhuo, Wei Wu, Yuxi Guo, Jiao Han, Linlin Jing, Xinyu Zhou, Xiancang Ma, Yan Li
Theranostics 2025; 15(6): 2139-2158. doi:10.7150/thno.103737
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3D bioprintable Mg²⁺-incorporated hydrogels tailored for regeneration of volumetric muscle loss
Moon Sung Kang, Jeong Min Kim, Hyo Jung Jo, Hye Jin Heo, Yun Hak Kim, Kyung Min Park, Dong-Wook Han
Theranostics 2025; 15(6): 2185-2200. doi:10.7150/thno.103677
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Autophagy-enhanced nanosonosensitizer mediated sonodynamic therapy for post-myocardial infarction neuromodulation and arrhythmia prevention
Haoyuan Hu, Songyun Wang, Qian Li, Jiahui Zhao, Yida Pang, Jiale Wang, Huijun Wu, Xinqi Wang, Ye Cheng, Mengran Yu, Xinyue Yin, Yan Zhang, Lilei Yu, Yao Sun, Hong Jiang
Theranostics 2025; 15(6): 2201-2214. doi:10.7150/thno.103780
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Targeted delivery of Grem1 and IL-10 separately by mesenchymal stem cells effectively mitigates SETD2-deficient inflammatory bowel disease
Rebiguli Aji, Yue Xu, Ziyi Wang, Wenxin Feng, Liming Gui, Hanyu Rao, Wei Zhang, Ningyuan Liu, Wei-Qiang Gao, Li Li
Theranostics 2025; 15(6): 2215-2228. doi:10.7150/thno.105876
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Extracellular matrix proteins refine microenvironments for pancreatic organogenesis from induced pluripotent stem cell differentiation
Ming Hu, Tianzheng Liu, Hui Huang, Derek Ogi, Yinfei Tan, Kaiming Ye, Sha Jin
Theranostics 2025; 15(6): 2229-2249. doi:10.7150/thno.104883
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Neurotrophic factor-α1/carboxypeptidase E controls progression and reversal of Alzheimer's disease pathogenesis in mice
Fang-Cheng Fan, Li-Ming Liu, Mei Guo, Yang Du, Yue-Wen Chen, Y. Peng Loh, Yong Cheng
Theranostics 2025; 15(6): 2279-2292. doi:10.7150/thno.99908
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USP14 modulates stem-like properties, tumorigenicity, and radiotherapy resistance in glioblastoma stem cells through stabilization of MST4-phosphorylated ALKBH5
Xiao Zhou, Qiaoxi Xia, Botao Wang, Junjun Li, Bing Liu, Sisi Wang, Min Huang, Ronghui Zhong, Shi-Yuan Cheng, Xuan Wang, Xiaobing Jiang, Tianzhi Huang
Theranostics 2025; 15(6): 2293-2314. doi:10.7150/thno.103629
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Neural mechanism of trigeminal nerve stimulation recovering defensive arousal responses in traumatic brain injury
Qian Zhang, Haiyun Ma, Lifang Huo, Shaoling Wang, Qian Yang, Zhimin Ye, Jie Cao, Shaoling Wu, Chao Ma, Congping Shang
Theranostics 2025; 15(6): 2315-2337. doi:10.7150/thno.106323
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Histone lactylation-driven B7-H3 expression promotes tumor immune evasion
Zhibo Ma, Jincui Yang, Wenlong Jia, Le Li, Yixin Li, Junjie Hu, Wei Luo, Ronghui Li, Dawei Ye, Peixiang Lan
Theranostics 2025; 15(6): 2338-2359. doi:10.7150/thno.105947
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Reviews

Metabolic regulation of myeloid-derived suppressor cells in tumor immune microenvironment: targets and therapeutic strategies
Hong Wang, Fei Zhou, Wenqing Qin, Yun Yang, Xiaojiaoyang Li, Runping Liu
Theranostics 2025; 15(6): 2159-2184. doi:10.7150/thno.105276
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Epigenetic regulation-mediated disorders in dopamine transporter endocytosis: A novel mechanism for the pathogenesis of Parkinson's disease
Ziqi Liang, Wanqing Liu, Mian Cao, Jiajun Cui, Jinshuai Lan, Yue Ding, Tong Zhang, Zizhao Yang
Theranostics 2025; 15(6): 2250-2278. doi:10.7150/thno.107436
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