◂ Last issue Next issue ▸ Archive
Volume 14 (17); 2024
Research Papers
Whole-body fluorescence cryotomography identifies a fast-acting, high-contrast, durable contrast agent for fluorescence-guided surgery
Augustino V. Scorzo, Brook K. Byrd, Caleb Y. Kwon, Rendall R. Strawbridge, Kimberley S. Samkoe, P. Jack Hoopes, Keith D. Paulsen, David W. Roberts, Scott C. Davis
Theranostics 2024; 14(17): 6426-6445. doi:10.7150/thno.100802
Full text
PDF
PubMed
PMC
Mitochondrial transfer balances cell redox, energy and metabolic homeostasis in the osteoarthritic chondrocyte preserving cartilage integrity
Angela C. Court, Ana María Vega-Letter, Eliseo Parra-Crisóstomo, Francesca Velarde, Cynthia García, Alexander Ortoloff, Rolando Vernal, Carolina Pradenas, Patricia Luz-Crawford, Maroun Khoury, Fernando E. Figueroa
Theranostics 2024; 14(17): 6471-6486. doi:10.7150/thno.96723
Full text
PDF
PubMed
PMC
Targeting the smooth muscle cell Keap1-Nrf2-GSDMD-pyroptosis axis by cryptotanshinone prevents abdominal aortic aneurysm formation
Jiaojiao Wang, Weile Ye, Jiami Zou, Pinglian Yang, Mei Jin, Zhihua Zheng, Chunhong Zhou, Wanlu Qiu, Jing Lu, Chengzhi Li, Shuai Guo, Yiming Xu, Zunnan Huang, Peiqing Liu, Zhiping Liu
Theranostics 2024; 14(17): 6516-6542. doi:10.7150/thno.98400
Full text
PDF
PubMed
PMC
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1
Meiqian Li, Yangyan Cui, Qi Qi, Jiakuan Liu, Jiaxuan Li, Guifang Huang, Jiale Yang, Jingya Sun, Zhihui Ma, Shengjie Liang, Dianzheng Zhang, Jun Jiang, Rujian Zhu, Qiuli Liu, Ruimin Huang, Jun Yan
Theranostics 2024; 14(17): 6543-6559. doi:10.7150/thno.101575
Full text
PDF
PubMed
PMC
Supramolecularly engineered bacteria mediated calcium overload and immunotherapy of tumors
Beibei Xie, Linmiao Dong, Leo Wang, Ruibing Wang, Chunlai Li
Theranostics 2024; 14(17): 6560-6570. doi:10.7150/thno.99931
Full text
PDF
PubMed
PMC
Biomineralized in situ catalytic nanoreactor integrated microneedle patch for on demand immunomodulator supply to combat psoriasis
Xiaodie Li, Minglong Chen, Xinni He, Jinghang Cong, Wanchen Zhao, Yanping Fu, Chao Lu, Chuanbin Wu, Xin Pan, Guilan Quan
Theranostics 2024; 14(17): 6571-6586. doi:10.7150/thno.101845
Full text
PDF
PubMed
PMC
Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis
Young Kim, Jee Ye Kim, Sol Moon, Hyojung Lee, Suji Lee, Joon Ye Kim, Min Woo Kim, Seung Il Kim
Theranostics 2024; 14(17): 6587-6604. doi:10.7150/thno.99245
Full text
PDF
PubMed
PMC
Hypothalamic P62 (SQSTM1) regulates energy balance by modulating leptin signaling
Shan Yang, Yang Li, Mingyuan Tian, Wuquan Deng, Dongfang Liu, Chen Chen, Zhiming Zhu, Hongting Zheng, Gangyi Yang, Ling Li, Mengliu Yang
Theranostics 2024; 14(17): 6605-6624. doi:10.7150/thno.96480
Full text
PDF
PubMed
PMC
Brain-to-heart cholinergic synapse-calcium signaling mediates ischemic stroke-induced atrial fibrillation
Yingran Liang, Gongxin Wang, Siwen Fan, Junyi Zhang, Shuang He, Guixiang Pan, Guoliang Hao, Yan Zhu
Theranostics 2024; 14(17): 6625-6651. doi:10.7150/thno.99065
Full text
PDF
PubMed
PMC
Macrophage membrane‒biomimetic nanoparticles target inflammatory microenvironment for epilepsy treatment
Chao Geng, Xinghui Ren, Peipei Cao, Xiaoqi Chu, Penghu Wei, Quanlei Liu, Yongchang Lu, Bin Fu, Wenyou Li, Yuhao Li, Guoguang Zhao
Theranostics 2024; 14(17): 6652-6670. doi:10.7150/thno.99260
Full text
PDF
PubMed
PMC
Lactoferrin docking NIR-II cyanine dye as a potentiated phototheranostic for synchronous multimodal bioimaging and tumor photo-immunotherapy
Lifeng Hang, Haijian Li, Meng Li, Yiqiang Sun, Wenjiao Wu, Laiping Fang, Yanzhao Diao, Hong Qu, Tao Zhang, Shumei Li, Guihua Jiang
Theranostics 2024; 14(17): 6671-6691. doi:10.7150/thno.102663
Full text
PDF
PubMed
PMC
Platelets camouflaged nanovehicle improved bladder cancer immunotherapy by triggering pyroptosis
Jiale Tian, Mingde Gao, Jinfeng Zhu, Haifei Xu, Hao Ji, Donglin Xia, Xiaolin Wang
Theranostics 2024; 14(17): 6692-6707. doi:10.7150/thno.99040
Full text
PDF
PubMed
PMC
Intracalvariosseous administration of donepezil microspheres protects against cognitive impairment by virtue of long-lasting brain exposure in mice
Ji Hee Kang, Jin-Kyoung Yang, Kyo Hee Cho, O Hyun Lee, Hayoon Kwon, Sun Yeou Kim, Sehoon Kim, Young Tag Ko
Theranostics 2024; 14(17): 6708-6725. doi:10.7150/thno.100986
Full text
PDF
PubMed
PMC
Role of damaged mitochondrial transfer in alpha-particle generator 212Pb radiation-induced bystander effect
Mengdie Yang, Lusheng Wang, Shanshan Qin, Xiongxin Dai, Jianguo Li, Liwei An, Lijuan Song, Jie Gao, Zongtai Han, Fei Yu
Theranostics 2024; 14(17): 6768-6782. doi:10.7150/thno.101922
Full text
PDF
PubMed
PMC
Low hepatic artery blood flow mediates NET extravasation through the regulation of PIEZO1/SRC signaling to induce biliary complications after liver transplantation
Hongqiang Yu, Yujun Zhang, Ling Shuai, Cong Peng, Changchun Zhao, Yan Jiang, Ling Yao, Jiejuan Lai, Zhiyu Chen, Leida Zhang, Xiang Xiong, Xiaojun Wang
Theranostics 2024; 14(17): 6783-6797. doi:10.7150/thno.99514
Full text
PDF
PubMed
PMC
DNASE1L3-mediated PANoptosis enhances the efficacy of combination therapy for advanced hepatocellular carcinoma
Jingchun Wang, Yu Chen, Yanquan Xu, Jiangang Zhang, Shuai Yang, Yu Zhou, Juan Lei, Ran Ren, Yang Chen, Huakan Zhao, Yongsheng Li, Shiming Yang
Theranostics 2024; 14(17): 6798-6817. doi:10.7150/thno.102995
Full text
PDF
PubMed
PMC
Real-time monitoring of single dendritic cell maturation using deep learning-assisted surface-enhanced Raman spectroscopy
Cai Zhang, Mengling Wang, Houde Wu, Hongmei Gao, Pengyun Wu, Li Guo, Dingbin Liu
Theranostics 2024; 14(17): 6818-6830. doi:10.7150/thno.100298
Full text
PDF
PubMed
PMC
Reviews
Aspects and prospects of preclinical theranostic radiopharmaceutical development
Bryce J.B. Nelson, Viktoria Krol, Aditya Bansal, Jan D. Andersson, Frank Wuest, Mukesh K. Pandey
Theranostics 2024; 14(17): 6446-6470. doi:10.7150/thno.100339
Full text
PDF
PubMed
PMC
Engineering mesenchymal stem cells for premature ovarian failure: overcoming challenges and innovating therapeutic strategies
Zijun Yuan, Yinping Zhang, Xinyu He, Xiang Wang, Xingyue Wang, Siqi Ren, Jiahong Su, Jing Shen, Xiang Li, Zhangang Xiao
Theranostics 2024; 14(17): 6487-6515. doi:10.7150/thno.102641
Full text
PDF
PubMed
PMC
Targeting sirtuins for cancer therapy: epigenetics modifications and beyond
Hui Shen, Xinyi Qi, Yue Hu, Yi Wang, Jin Zhang, Zhongyu Liu, Zheng Qin
Theranostics 2024; 14(17): 6726-6767. doi:10.7150/thno.100667
Full text
PDF
PubMed
PMC
Harnessing glucose metabolism with nanomedicine for cancer treatment
Xudong Wang, Liping Wang, Qingyi Hao, Meng Cai, Xueting Wang, Wenlin An
Theranostics 2024; 14(17): 6831-6882. doi:10.7150/thno.100036
Full text
PDF
PubMed
PMC