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Theranostics 2023; 13(1):161-196. doi:10.7150/thno.79639 This issue Cite

Review

Recent advances in the medical applications of hemostatic materials

Yu Guo1*, Min Wang1*, Qi Liu1, Guoliang Liu2, Shuang Wang3✉, Jiannan Li1✉

1. Department of the General Surgery, Jilin University Second Hospital, Changchun, China.
2. Department of Operating Theater and Anesthesiology, Jilin University Second Hospital, Changchun, China.
3. Department of the Dermatology, Jilin University Second Hospital, Changchun, China.
* Equally contributed to this work.

✉ Corresponding authors: Shuang Wang, E-mail: jdeywangshuangcom, Department of the Dermatology, Jilin University Second Hospital, Changchun, China. Jiannan Li, E-mail: jnliac.cn, Department of the General Surgery, Jilin University Second Ho More

Citation:
Guo Y, Wang M, Liu Q, Liu G, Wang S, Li J. Recent advances in the medical applications of hemostatic materials. Theranostics 2023; 13(1):161-196. doi:10.7150/thno.79639. https://www.thno.org/v13p0161.htm
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Abstract

Graphic abstract

Bleeding caused by trauma or surgery is a serious health problem, and uncontrollable bleeding can result in death. Therefore, developing safe, effective, and convenient hemostatic materials is important. Active hemostatic agents currently used to investigate the field of hemostasis are divided into four broad categories: natural polymers, synthetic polymers, inorganic materials, and metal-containing materials. Hemostatic materials are prepared in various forms for wound care applications based on the active ingredients used. These materials include nanofibers, gels, sponges, and nanoparticles. Hemostatic materials find their applications in the field of wound care, and they are also used for hemostasis during malignant tumor surgery. Prompt and effective hemostasis can reduce the possibility of the spread of tumor cells with blood. This review discusses the outcomes of current research conducted in the field and the problems persisting in the field of developing hemostatic materials. The review also presents a platform for the further development of hemostatic materials. Bleeding caused by trauma or surgery is a serious health problem, and uncontrollable bleeding can result in death. Therefore, developing safe, effective, and convenient hemostatic materials is important. Active hemostatic agents currently used to investigate the field of hemostasis are divided into four broad categories: natural polymers, synthetic polymers, inorganic materials, and metal-containing materials. Hemostatic materials are prepared in various forms for wound care applications based on the active ingredients used. These materials include nanofibers, gels, sponges, and nanoparticles. Hemostatic materials find their applications in the field of wound care, and they are also used for hemostasis during malignant tumor surgery. Prompt and effective hemostasis can reduce the possibility of the spread of tumor cells with blood. This review discusses the outcomes of current research conducted in the field and the problems persisting in the field of developing hemostatic materials. The review also presents a platform for the further development of hemostatic materials.

Keywords: hemostatic materials, polymer, nanofibers, hydrogels, medical use.

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APA
Guo, Y., Wang, M., Liu, Q., Liu, G., Wang, S., Li, J. (2023). Recent advances in the medical applications of hemostatic materials. Theranostics, 13(1), 161-196. https://doi.org/10.7150/thno.79639.

ACS
Guo, Y.; Wang, M.; Liu, Q.; Liu, G.; Wang, S.; Li, J. Recent advances in the medical applications of hemostatic materials. Theranostics 2023, 13 (1), 161-196. DOI: 10.7150/thno.79639.

NLM
Guo Y, Wang M, Liu Q, Liu G, Wang S, Li J. Recent advances in the medical applications of hemostatic materials. Theranostics 2023; 13(1):161-196. doi:10.7150/thno.79639. https://www.thno.org/v13p0161.htm

CSE
Guo Y, Wang M, Liu Q, Liu G, Wang S, Li J. 2023. Recent advances in the medical applications of hemostatic materials. Theranostics. 13(1):161-196.

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