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Volume 7 (14); 2017

Research Paper

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Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo
Genna Davies, Anna-Maria Rolle, Andreas Maurer, Philipp R. Spycher, Claudia Schillinger, Djamschid Solouk-Saran, Mike Hasenberg, Juliane Weski, Jesper Fonslet, Adrien Dubois, Frederic Boschetti, Franck Denat, Matthias Gunzer, Martin Eichner, Lauren S Ryder, Mikael Jensen, Roger Schibli, Bernd J. Pichler, Stefan Wiehr, Christopher R. Thornton
Theranostics 2017; 7(14): 3398-3414. doi:10.7150/thno.20919
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Brusatol-Mediated Inhibition of c-Myc Increases HIF-1α Degradation and Causes Cell Death in Colorectal Cancer under Hypoxia
Eun-Taex Oh, Chan Woo Kim, Ha Gyeong Kim, Jae-Seon Lee, Heon Joo Park
Theranostics 2017; 7(14): 3415-3431. doi:10.7150/thno.20861
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The pH-Triggered Triblock Nanocarrier Enabled Highly Efficient siRNA Delivery for Cancer Therapy
Lili Du, Junhui Zhou, Lingwei Meng, Xiaoxia Wang, Changrong Wang, Yuanyu Huang, Shuquan Zheng, Liandong Deng, Huiqing Cao, Zicai Liang, Anjie Dong, Qiang Cheng
Theranostics 2017; 7(14): 3432-3445. doi:10.7150/thno.20297
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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rSj16 Protects against DSS-Induced Colitis by Inhibiting the PPAR-α Signaling Pathway
Lifu Wang, Hui Xie, Lian Xu, Qi Liao, Shuo Wan, Zilong Yu, Datao Lin, Beibei Zhang, Zhiyue Lv, Zhongdao Wu, Xi Sun
Theranostics 2017; 7(14): 3446-3460. doi:10.7150/thno.20359
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Sulforaphane-Induced Cell Cycle Arrest and Senescence are accompanied by DNA Hypomethylation and Changes in microRNA Profile in Breast Cancer Cells
Anna Lewinska, Jagoda Adamczyk-Grochala, Anna Deregowska, Maciej Wnuk
Theranostics 2017; 7(14): 3461-3477. doi:10.7150/thno.20657
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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CBX8 Suppresses Tumor Metastasis via Repressing Snail in Esophageal Squamous Cell Carcinoma
Gang Wang, Jianjun Tang, Weixiang Zhan, Ruhua Zhang, Meifang Zhang, Dan Liao, Xin Wang, Yuanzhong Wu, Tiebang Kang
Theranostics 2017; 7(14): 3478-3488. doi:10.7150/thno.20717
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Glioma Dual-Targeting Nanohybrid Protein Toxin Constructed by Intein-Mediated Site-Specific Ligation for Multistage Booster Delivery
Yingzhi Chen, Meng Zhang, Hongyue Jin, Dongdong Li, Fan Xu, Aihua Wu, Jinyu Wang, Yongzhuo Huang
Theranostics 2017; 7(14): 3489-3503. doi:10.7150/thno.20578
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Real-time In vivo Diagnosis of Nasopharyngeal Carcinoma Using Rapid Fiber-Optic Raman Spectroscopy
Kan Lin, Wei Zheng, Chwee Ming Lim, Zhiwei Huang
Theranostics 2017; 7(14): 3517-3526. doi:10.7150/thno.16359
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The Role of Nitric Oxide during Sonoreperfusion of Microvascular Obstruction
Francois T.H. Yu, Xucai Chen, Adam C. Straub, John J. Pacella
Theranostics 2017; 7(14): 3527-3538. doi:10.7150/thno.19422
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Genetically Encoded Photoactuators and Photosensors for Characterization and Manipulation of Pluripotent Stem Cells
Jordan E. Pomeroy, Hung X. Nguyen, Brenton D. Hoffman, Nenad Bursac
Theranostics 2017; 7(14): 3539-3558. doi:10.7150/thno.20593
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Mass spectrometry-assisted gel-based proteomics in cancer biomarker discovery: approaches and application
Rongrong Huang, Zhongsi Chen, Lei He, Nongyue He, Zhijiang Xi, Zhiyang Li, Yan Deng, Xin Zeng
Theranostics 2017; 7(14): 3559-3572. doi:10.7150/thno.20797
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Investigation of the Safety of Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Natural Canine Model of Aging
Meaghan Anne O'Reilly, Ryan Matthew Jones, Edward Barrett, Anthony Schwab, Elizabeth Head, Kullervo Hynynen
Theranostics 2017; 7(14): 3573-3584. doi:10.7150/thno.20621
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Genomic Analysis of Tumor Microenvironment Immune Types across 14 Solid Cancer Types: Immunotherapeutic Implications
Yu-Pei Chen, Yu Zhang, Jia-Wei Lv, Ying-Qin Li, Ya-Qin Wang, Qing-Mei He, Xiao-Jing Yang, Ying Sun, Yan-Ping Mao, Jing-Ping Yun, Na Liu, Jun Ma
Theranostics 2017; 7(14): 3585-3594. doi:10.7150/thno.21471
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFRβ Aptamer
Simona Camorani, Billy Samuel Hill, Raffaela Fontanella, Adelaide Greco, Matteo Gramanzini, Luigi Auletta, Sara Gargiulo, Sandra Albanese, Enrico Lucarelli, Laura Cerchia, Antonella Zannetti
Theranostics 2017; 7(14): 3595-3607. doi:10.7150/thno.18974
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

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Bioengineering of Artificial Antigen Presenting Cells and Lymphoid Organs
Chao Wang, Wujin Sun, Yanqi Ye, Hunter N. Bomba, Zhen Gu
Theranostics 2017; 7(14): 3504-3516. doi:10.7150/thno.19017
[Abstract] [Full text] [PDF] [PubMed] [PMC]