ISSN: 1838-7640Theranostics
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Theranostics 2023; 13(6):2015-2039. doi:10.7150/thno.80615 This issue Cite
Review
Recent advances in GelMA hydrogel transplantation for musculoskeletal disorders and related disease treatment
1. Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 P.R. China.
2. Pingshan District People's Hospital of Shenzhen, Pingshan General Hospital of Southern Medical University, Shenzhen, 518118 P.R. China.
3. Third School of Clinical Medicine, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028 P.R. China.
†Bin Lv, Li Lu, Liangcong Hu and Peng Cheng contributed equally to this work.
Citation:
Lv B, Lu L, Hu L, Cheng P, Hu Y, Xie X, Dai G, Mi B, Liu X, Liu G. Recent advances in GelMA hydrogel transplantation for musculoskeletal disorders and related disease treatment. Theranostics 2023; 13(6):2015-2039. doi:10.7150/thno.80615. https://www.thno.org/v13p2015.htm
Other stylesAbstract
Increasing data reveals that gelatin that has been methacrylated is involved in a variety of physiologic processes that are important for therapeutic interventions. Gelatin methacryloyl (GelMA) hydrogel is a highly attractive hydrogels-based bioink because of its good biocompatibility, low cost, and photo-cross-linking structure that is useful for cell survivability and cell monitoring. Methacrylated gelatin (GelMA) has established itself as a typical hydrogel composition with extensive biomedical applications. Recent advances in GelMA have focused on integrating them with bioactive and functional nanomaterials, with the goal of improving GelMA's physical, chemical, and biological properties. GelMA's ability to modify characteristics due to the synthesis technique also makes it a good choice for soft and hard tissues. GelMA has been established to become an independent or supplementary technology for musculoskeletal problems. Here, we systematically review mechanism-of-action, therapeutic uses, and challenges and future direction of GelMA in musculoskeletal disorders. We give an overview of GelMA nanocomposite for different applications in musculoskeletal disorders, such as osteoarthritis, intervertebral disc degeneration, bone regeneration, tendon disorders and so on.
Keywords: tissue engineering, hydrogel, nanomaterials, musculoskeletal disorders, bone
Citation styles
APA
Lv, B., Lu, L., Hu, L., Cheng, P., Hu, Y., Xie, X., Dai, G., Mi, B., Liu, X., Liu, G. (2023). Recent advances in GelMA hydrogel transplantation for musculoskeletal disorders and related disease treatment. Theranostics, 13(6), 2015-2039. https://doi.org/10.7150/thno.80615.
ACS
Lv, B.; Lu, L.; Hu, L.; Cheng, P.; Hu, Y.; Xie, X.; Dai, G.; Mi, B.; Liu, X.; Liu, G. Recent advances in GelMA hydrogel transplantation for musculoskeletal disorders and related disease treatment. Theranostics 2023, 13 (6), 2015-2039. DOI: 10.7150/thno.80615.
NLM
Lv B, Lu L, Hu L, Cheng P, Hu Y, Xie X, Dai G, Mi B, Liu X, Liu G. Recent advances in GelMA hydrogel transplantation for musculoskeletal disorders and related disease treatment. Theranostics 2023; 13(6):2015-2039. doi:10.7150/thno.80615. https://www.thno.org/v13p2015.htm
CSE
Lv B, Lu L, Hu L, Cheng P, Hu Y, Xie X, Dai G, Mi B, Liu X, Liu G. 2023. Recent advances in GelMA hydrogel transplantation for musculoskeletal disorders and related disease treatment. Theranostics. 13(6):2015-2039.
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