Theranostics 2022; 12(12):5335-5336. doi:10.7150/thno.76351 This issue

Erratum

Evaluation of 18F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue: Erratum

François-Xavier Lepelletier1,2*, Matthias Vandesquille1,2*, Marie-Claude Asselin2,3, Christian Prenant2, Andrew C Robinson4, David M A Mann4, Michael Green2,3, Elizabeth Barnett2,3, Samuel D Banister5, Marco Mottinelli6, Christophe Mesangeau7, Christopher R McCurdy6,8, Inga B Fricke9*, Andreas H. Jacobs9,10, Michael Kassiou5, Hervé Boutin1,2 Corresponding address

1. Faculty of Biology, Medicine and Health, School of Biological Sciences, Division of Neuroscience and Experimental Psychology, University of Manchester, Manchester, United Kingdom.
2. Wolfson Molecular Imaging Centre, University of Manchester, Manchester, United Kingdom.
3. Faculty of Biology, Medicine and Health, School of Health Sciences, Division of Informatics, Imaging and Data Sciences, University of Manchester, Manchester, United Kingdom.
4. Salford Royal NHS Foundation Trust, Department of Clinical & Cognitive Neurosciences, Clinical Sciences Building, Salford, United Kingdom.
5. School of Chemistry, The University of Sydney, Sydney, Australia.
6. Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
7. Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
8. UF Translational Drug Development Core, University of Florida, Gainesville, FL 32610, USA.
9. European Institute for Molecular Imaging (EIMI), Westfälische Wilhelms-Universität (WWU), Münster, Germany.
10. Department of Geriatrics and Neurology, Johanniter Hospital, Bonn, Germany.
*Current addresses: FXL: Université de Caen Normandie, IUT Grand Ouest Normandie, Département Hygiène Sécurité Environnement, Rue des Noës Davy 14500 Vire-Normandie (E-mail: fx.lepelletier@gmail.com); MV: Institut Européen de Génomique du Diabète, 1 place de Verdun, 59045 Lille, France (E-mail: matthias.vandesquille@univ-lille.fr); IF: Bruker BioSpin MRI GmbH, Rudolf-Plank-Str. 23, 76275 Ettlingen, Germany (E-mail: inga.fricke@bruker.com).

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
Citation:
Lepelletier FX, Vandesquille M, Asselin MC, Prenant C, Robinson AC, Mann DMA, Green M, Barnett E, Banister SD, Mottinelli M, Mesangeau C, McCurdy CR, Fricke IB, Jacobs AH, Kassiou M, Boutin H. Evaluation of 18F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue: Erratum. Theranostics 2022; 12(12):5335-5336. doi:10.7150/thno.76351. Available from https://www.thno.org/v12p5335.htm

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Corrected-article in Theranostics, Volume 10, 7938

 

The authors regret that the original version of our paper unfortunately contained incorrect data in Figure 2B, where the vertical plot of the ROIs significantly different of the mesencephalic region (x-axis, right hand side of the graph) were incorrect and did not match the horizontal level of significant differences. The correct version of the Figure 2B is shown below.

The corrections made in this erratum do not affect the original conclusions. The authors apologize for any inconvenience that the errors may have caused.

 Figure 2 

(A) Average uptake (from sum-image 20-60min post-injection) of 18F-IAM6067 in different brain regions in rats (n=8, data are expressed as SUV mean ± SD). (B) Heat map of the adjusted P values (Sidak's post-hoc test) showing all the comparisons between the various brain regions for 18F-IAM6067 uptake. Non-significant differences are shown in blue. (C) PET sum-image (20-60min) co-registered with CT showing 18F-IAM6067 uptake with hippocampus, thalamus medio-dorsal, frontoparietal somatosensory cortex and amygdala highlighted by dotted lines.

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Author contact

Corresponding address Corresponding author: Hervé Boutin, Wolfson Molecular Imaging Centre, University of Manchester, 27 Palatine Road, Manchester, M20 3LJ, UK; E-mail: herve.boutinac.uk; Phone: +44 161 275 0078.


Published 2022-7-8