◂ Last issue Next issue ▸ Archive Cover PDF
Volume 11 (7); 2021
Research Papers
Systematic analysis of enhancer regulatory circuit perturbation driven by copy number variations in malignant glioma Jun Xiao, Xiaoyan Jin, Chunlong Zhang, Haozhe Zou, Zhenghong Chang, Nan Han, Xia Li, Yunpeng Zhang, Yongsheng Li
Theranostics 2021; 11(7): 3060-3073. doi:10.7150/thno.54150
Full text
PDF
PubMed
PMC
Highly specific and label-free histological identification of microcrystals in fresh human gout tissues with stimulated Raman scattering Bohan Zhang, Hanlin Xu, Jun Chen, Xiaoxia Zhu, Yu Xue, Yifan Yang, Jianpeng Ao, Yinghui Hua, Minbiao Ji
Theranostics 2021; 11(7): 3074-3088. doi:10.7150/thno.53755
Full text
PDF
PubMed
PMC
Siglec15 shapes a non-inflamed tumor microenvironment and predicts the molecular subtype in bladder cancer Jiao Hu, Anze Yu, Belaydi Othmane, Dongxu Qiu, Huihuang Li, Chao Li, Peihua Liu, Wenbiao Ren, Minfeng Chen, Guanghui Gong, Xi Guo, Huihui Zhang, Jinbo Chen, Xiongbing Zu
Theranostics 2021; 11(7): 3089-3108. doi:10.7150/thno.53649
Full text
PDF
PubMed
PMC
Nasal administration of mitochondria reverses chemotherapy-induced cognitive deficits Jenolyn F. Alexander, Alexandre V. Seua, Luis D. Arroyo, Pradipta R. Ray, Andi Wangzhou, Laura Heiβ-Lückemann, Manfred Schedlowski, Theodore J. Price, Annemieke Kavelaars, Cobi J. Heijnen
Theranostics 2021; 11(7): 3109-3130. doi:10.7150/thno.53474
Full text
PDF
PubMed
PMC
Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway Tzu-Lin Lee, Tsai-Chun Lai, Shu-Rung Lin, Shu-Wha Lin, Yu-Chen Chen, Chi-Ming Pu, I-Ta Lee, Jaw-Shiun Tsai, Chiang-Wen Lee, Yuh-Lien Chen
Theranostics 2021; 11(7): 3131-3149. doi:10.7150/thno.52677
Full text
PDF
PubMed
PMC
PHB2 promotes tumorigenesis via RACK1 in non-small cell lung cancer Bin Wu, Ning Chang, Hangtian Xi, Jie Xiong, Ying Zhou, Yingtong Wu, Shuo Wu, Ning Wang, Hongyu Yi, Yun Song, Lihua Chen, Jian Zhang
Theranostics 2021; 11(7): 3150-3166. doi:10.7150/thno.52848
Full text
PDF
PubMed
PMC
Holo-lactoferrin: the link between ferroptosis and radiotherapy in triple-negative breast cancer Zheng Zhang, Menglan Lu, Cailong Chen, Xing Tong, Yunhong Li, Kai Yang, Haitao Lv, Jiaying Xu, Liqiang Qin
Theranostics 2021; 11(7): 3167-3182. doi:10.7150/thno.52028
Full text
PDF
PubMed
PMC
Metallothionein-1G suppresses pancreatic cancer cell stemness by limiting activin A secretion via NF-κB inhibition Kai Li, Zhicheng Zhang, Yu Mei, Qingzhu Yang, Shupei Qiao, Cheng Ni, Yao Yao, Xinyuan Li, Mengmeng Li, Dongdong Wei, Wangjun Fu, Xuefei Guo, Xuemei Huang, Huanjie Yang
Theranostics 2021; 11(7): 3196-3212. doi:10.7150/thno.51976
Full text
PDF
PubMed
PMC
Prussian blue nanozyme-mediated nanoscavenger ameliorates acute pancreatitis via inhibiting TLRs/NF-κB signaling pathway Xue Xie, Jiulong Zhao, Wei Gao, Jie Chen, Bing Hu, Xiaojun Cai, Yuanyi Zheng
Theranostics 2021; 11(7): 3213-3228. doi:10.7150/thno.52010
Full text
PDF
PubMed
PMC
Large-scale tumor-associated collagen signatures identify high-risk breast cancer patients Gangqin Xi, Wenhui Guo, Deyong Kang, Jianli Ma, Fangmeng Fu, Lida Qiu, Liqin Zheng, Jiajia He, Na Fang, Jianhua Chen, Jingtong Li, Shuangmu Zhuo, Xiaoxia Liao, Haohua Tu, Lianhuang Li, Qingyuan Zhang, Chuan Wang, Stephen A. Boppart, Jianxin Chen
Theranostics 2021; 11(7): 3229-3243. doi:10.7150/thno.55921
Full text
PDF
PubMed
PMC
Co-delivery of siPTPN13 and siNOX4 via (myo)fibroblast-targeting polymeric micelles for idiopathic pulmonary fibrosis therapy Jiwei Hou, Qijian Ji, Jie Ji, Shenghong Ju, Chun Xu, Xueqing Yong, Xiaoxuan Xu, Mohd. Muddassir, Xiang Chen, Jinbing Xie, Xiaodong Han
Theranostics 2021; 11(7): 3244-3261. doi:10.7150/thno.54217
Full text
PDF
PubMed
PMC
RGD-expressed bacterial membrane-derived nanovesicles enhance cancer therapy via multiple tumorous targeting Jin Gao, Sihan Wang, Xinyue Dong, Zhenjia Wang
Theranostics 2021; 11(7): 3301-3316. doi:10.7150/thno.51988
Full text
PDF
PubMed
PMC
An in vitro model using spheroids-laden nanofibrous structures for attaining high degree of myoblast alignment and differentiation Miji Yeo, SooJung Chae, GeunHyung Kim
Theranostics 2021; 11(7): 3331-3347. doi:10.7150/thno.53928
Full text
PDF
PubMed
PMC
SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing Song Zhu, Weiping Chen, Jizhong Wang, Ling Qi, Huilin Pan, Zhengfu Feng, Dongbo Tian
Theranostics 2021; 11(7): 3359-3375. doi:10.7150/thno.51360
Full text
PDF
PubMed
PMC
Hypoxia-induced Nur77 activates PI3K/Akt signaling via suppression of Dicer/let-7i-5p to induce epithelial-to-mesenchymal transition Zeyu Shi, Sally K. Y. To, Shuaishuai Zhang, Shan Deng, Margarita Artemenko, Minda Zhang, Juan Tang, Jin-Zhang Zeng, Alice S.T. Wong
Theranostics 2021; 11(7): 3376-3391. doi:10.7150/thno.52190
Full text
PDF
PubMed
PMC
ILT4 inhibition prevents TAM- and dysfunctional T cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in NSCLC with EGFR activation Xiaozheng Chen, Aiqin Gao, Fang Zhang, Zijiang Yang, Shuyun Wang, Yuying Fang, Juan Li, Jingnan Wang, Wenjing Shi, Linlin Wang, Yan Zheng, Yuping Sun
Theranostics 2021; 11(7): 3392-3416. doi:10.7150/thno.52435
Full text
PDF
PubMed
PMC
Colon tissue-accumulating mesoporous carbon nanoparticles loaded with Musca domestica cecropin for ulcerative colitis therapy Lun Zhang, Shuiqing Gui, Yinghua Xu, Jiali Zeng, Jian Wang, Qingru Chen, Liqian Su, Ziyan Wang, Rui Deng, Fujiang Chu, Wenbin Liu, Xiaobao Jin, Xuemei Lu
Theranostics 2021; 11(7): 3417-3438. doi:10.7150/thno.53105
Full text
PDF
PubMed
PMC
Targeting miR-21 with NL101 blocks c-Myc/Mxd1 loop and inhibits the growth of B cell lymphoma Shu Li, Xin He, Yichao Gan, Jiawei Zhang, Feiqiong Gao, Limin Lin, Xi Qiu, Teng Yu, Xuzhao Zhang, Panpan Chen, Jiefeng Tong, Wenbin Qian, Yang Xu
Theranostics 2021; 11(7): 3439-3451. doi:10.7150/thno.53561
Full text
PDF
PubMed
PMC
Mutation of SPINOPHILIN (PPP1R9B) found in human tumors promotes the tumorigenic and stemness properties of cells Eva M Verdugo-Sivianes, Ana M Rojas, Sandra Muñoz-Galván, Daniel Otero-Albiol, Amancio Carnero
Theranostics 2021; 11(7): 3452-3471. doi:10.7150/thno.53572
Full text
PDF
PubMed
PMC
Overall survival of pancreatic ductal adenocarcinoma is doubled by Aldh7a1 deletion in the KPC mouse Jae-Seon Lee, Ho Lee, Sang Myung Woo, Hyonchol Jang, Yoon Jeon, Hee Yeon Kim, Jaewhan Song, Woo Jin Lee, Eun Kyung Hong, Sang-Jae Park, Sung-Sik Han, Soo-Youl Kim
Theranostics 2021; 11(7): 3472-3488. doi:10.7150/thno.53935
Full text
PDF
PubMed
PMC
Cell membranes targeted unimolecular prodrug for programmatic photodynamic-chemo therapy Jie Yuan, Rong Peng, Dongdong Su, Xingxing Zhang, Hepeng Zhao, Xiujuan Zhuang, Mei Chen, Xiaobing Zhang, Lin Yuan
Theranostics 2021; 11(7): 3502-3511. doi:10.7150/thno.55014
Full text
PDF
PubMed
PMC
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1 Qizhen Cao, Qian Huang, Y. Alan Wang, Chun Li
Theranostics 2021; 11(7): 3527-3539. doi:10.7150/thno.49421
Full text
PDF
PubMed
PMC
Reviews
Optical Tissue Clearing: Illuminating Brain Function and Dysfunction Xiaohan Liang, Haiming Luo
Theranostics 2021; 11(7): 3035-3051. doi:10.7150/thno.53979
Full text
PDF
PubMed
PMC
Ferroptosis as a novel therapeutic target for cardiovascular disease Xiaoguang Wu, Yi Li, Shuchen Zhang, Xiang Zhou
Theranostics 2021; 11(7): 3052-3059. doi:10.7150/thno.54113
Full text
PDF
PubMed
PMC
Engineering exosomes for targeted drug delivery Yujie Liang, Li Duan, Jianping Lu, Jiang Xia
Theranostics 2021; 11(7): 3183-3195. doi:10.7150/thno.52570
Full text
PDF
PubMed
PMC
Semaphorins as emerging clinical biomarkers and therapeutic targets in cancer Roberta Mastrantonio, Hua You, Luca Tamagnone
Theranostics 2021; 11(7): 3262-3277. doi:10.7150/thno.54023
Full text
PDF
PubMed
PMC
Recent advances in innovative strategies for enhanced cancer photodynamic therapy Tingting Hu, Zhengdi Wang, Weicheng Shen, Ruizheng Liang, Dan Yan, Min Wei
Theranostics 2021; 11(7): 3278-3300. doi:10.7150/thno.54227
Full text
PDF
PubMed
PMC
Organ-organ communication: The liver's perspective Fei Wang, Kwok-Fai So, Jia Xiao, Hua Wang
Theranostics 2021; 11(7): 3317-3330. doi:10.7150/thno.55795
Full text
PDF
PubMed
PMC
Roles of peptidyl-prolyl isomerase Pin1 in disease pathogenesis Jingyi Li, Chunfen Mo, Yifan Guo, Bowen Zhang, Xiao Feng, Qiuyue Si, Xiaobo Wu, Zhe Zhao, Lixin Gong, Dan He, Jichun Shao
Theranostics 2021; 11(7): 3348-3358. doi:10.7150/thno.45889
Full text
PDF
PubMed
PMC
Immunotherapy for targeting cancer stem cells in hepatocellular carcinoma Xiaomeng Dai, Yixuan Guo, Yan Hu, Xuanwen Bao, Xudong Zhu, Qihan Fu, Hangyu Zhang, Zhou Tong, Lulu Liu, Yi Zheng, Peng Zhao, Weijia Fang
Theranostics 2021; 11(7): 3489-3501. doi:10.7150/thno.54648
Full text
PDF
PubMed
PMC
Ovarian hormones-autophagy-immunity axis in menstruation and endometriosis Hui-Hui Shen, Tao Zhang, Hui-Li Yang, Zhen-Zhen Lai, Wen-Jie Zhou, Jie Mei, Jia-Wei Shi, Rui Zhu, Feng-Yuan Xu, Da-Jin Li, Jiang-Feng Ye, Ming-Qing Li
Theranostics 2021; 11(7): 3512-3526. doi:10.7150/thno.55241
Full text
PDF
PubMed
PMC
Global reach, higher impact
