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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

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Research Paper
Targeting tumor cell-to-macrophage communication by blocking Vtn-C1qbp interaction inhibits tumor progression via enhancing macrophage phagocytosis
Chen Zhang, Yi Liu, Jiayu Jiang, Chong Chen, Zhaojun Duan, Huifang Su, Shijian Wang, Baorui Tian, Yi Shi, Rong Xiang, Yunping Luo
Theranostics 2024; 14(7): 2757-2776. doi:10.7150/thno.94537
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Review
Prostate-specific membrane antigen-targeted surgery in prostate cancer: Accurate identification, real-time diagnosis, and precise resection
Jianhua Jiao, Jingjing Zhang, Weihong Wen, Weijun Qin, Xiaoyuan Chen
Theranostics 2024; 14(7): 2736-2756. doi:10.7150/thno.95039
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Research Paper
Bifidobacterium breve-derived indole-3-lactic acid ameliorates colitis-associated tumorigenesis by directing the differentiation of immature colonic macrophages
Yuke Li, Qingxiang Li, Ruoshui Yuan, Yifei Wang, Chuanbin Guo, Lin Wang
Theranostics 2024; 14(7): 2719-2735. doi:10.7150/thno.92350
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Research Paper
Hyperglycemia facilitates EV71 replication: Insights into miR-206-mediated regulation of G3BP2 promoting EV71 IRES activity
Rai-Hua Lai, Yen-Hung Chow, Yi-Wen Lin, Nai-Hsiang Chung, Shu-Wei Nien, Jyh-Lyh Juang
Theranostics 2024; 14(7): 2706-2718. doi:10.7150/thno.93883
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Research Paper
Abnormal mitochondrial iron metabolism damages alveolar type II epithelial cells involved in bleomycin-induced pulmonary fibrosis
Min Shao, Haipeng Cheng, Xiaohong Li, Yujia Qiu, Yunna Zhang, Yanfen Chang, Jiafeng Fu, Mengxia Shen, Xinxin Xu, Dandan Feng, Yang Han, ShaoJie Yue, Yan Zhou, Ziqiang Luo
Theranostics 2024; 14(7): 2687-2705. doi:10.7150/thno.94072
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Research Paper
Albumin-seeking dyes with adjustable assemblies in situ enable programmable imaging windows and targeting tumor imaging
Yijing Du, Jiajun Xu, Tianyang Han, Zijian Jiang, Yuewei Zhang, Jia Li, Xiaoyuan Chen, Shoujun Zhu
Theranostics 2024; 14(7): 2675-2686. doi:10.7150/thno.92991
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Research Paper
AXL-specific single domain antibodies show diagnostic potential and anti-tumor activity in Acute Myeloid Leukemia
Niels Vandewalle, Hatice Satilmis, Emma Verheye, Rong Fan, Yanmeng Wang, Timo W.M. De Groof, Jessica Bridoux, Tessa Kerre, Nathan De Beule, Ann De Becker, Elke De Bruyne, Eline Menu, Karin Vanderkerken, Karine Breckpot, Nick Devoogdt, Kim De Veirman
Theranostics 2024; 14(7): 2656-2674. doi:10.7150/thno.91456
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Research Paper
Size control of ropivacaine nano/micro-particles by soft-coating with peptide nanosheets for long-acting analgesia
Jing Liu, Weiwei Wu, Fei Peng, Deying Gong, Yi Kang, Yujun Zhang, Congyan Liu, Yuncheng Li, Guoyan Zhao, Feng Qiu, Wensheng Zhang
Theranostics 2024; 14(6): 2637-2655. doi:10.7150/thno.93322
Abstract Full text PDF PubMed PMC

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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile

new Congratulations! Professor Chen has been elected as a member of the Academia Europaea.

CFP - Special issue on Molecular Imaging and Theranostics. Guest Editors: Dr. Jianhua Zou, Dr. Jingjing Zhang and Dr. Mengyao Zhao.

Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr. Magali Cucchiarini.

Radical prostatectomy (RP) combined with pelvic lymph node dissection (PLND) is the first step in multimodal treatment of prostate cancer (PCa) without distant metastases. For a long time, the surgical resection range has been highly dependent on the surgeon's visualization and experience with preoperative imaging. With the rapid development of prostate-specific membrane antigen positron emission tomography and single-photon emission computed tomography (PSMA-PET and PSMA-SPECT), PSMA-targeted surgery has been introduced for a more accurate pathological diagnosis and complete resection of positive....
Cyanine dyes are widely used organic probes for in vivo imaging due to their tunable fluorescence. They can form complexes with endogenous albumin, resulting in enhanced brightness and photostability. However, this binding is uncontrollable and irreversible, leading to considerable nonspecific background signals and unregulated circulation time. Methods: Here, we connect varying numbers of 4-(4-iodophenyl) butanoic acid (IP) as albumin-binding moieties (ABM) to the cyanine dye, enabling dynamic and controllable binding with albumin. Meanwhile, we provide a blocking method to completely release....

Nanotheranostics is indexed in MEDLINE and PubMed Central ...

Research Paper
Dual Functional Magnetic Nanoparticles Conjugated with Carbon Quantum Dots for Hyperthermia and Photodynamic Therapy for Cancer
Mounika Choppadandi, Kondi Soumya, Sumanta Ghosh, Aishwarya Balu, Tanvi Shingote, Srivalliputtur Sarath Babu, Vani Sai Prasanna, Somasundaram Arumugam, Ravichandiran Velyutham, Murali M. Yallapu, Govinda Kapusetti
Nanotheranostics 2024; 8(4): 442-457. doi:10.7150/ntno.91871
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