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Research Paper DCTN2 inhibited cellular senescence through targeting TRIM21 mediated MST2 ubiquitination and activation in hepatocellular carcinoma Yanbo Wang, Yaomei He, Qin Yu, Ningrui Wang, Qiaoling Ruan, Haiyan Wang, Hanqing Zhao, Yonglin Zhang, Yang Ke, Caie Tang, Liqi Lang, Yuxia Tang, Lixia Liu, Hao Zhang, Shan Yan, Aimin Wang, Qiushuo Shen, Ceshi Chen Theranostics 2026; 16(16): 9165-9184. doi:10.7150/thno.137790 Full text PDF


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Research Paper A nanoengineered MSC therapeutic for synergistic therapy of lupus nephritis via cfDNA clearance and targeted immunomodulation Jiang Tian, Qinyao Xu, Zexin Wang, Zeyu Wang, Haofang Zhu, Lingyun Sun, Zhongwei Gu Theranostics 2026; 16(16): 9145-9164. doi:10.7150/thno.136356 Full text PDF


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Review Atherosclerosis nanotheranostics: a perspective from macrophages Caiyan Zhao, Jiakun Zhang, Rujie Wang, Shen’ao Wang, Hongzhang Deng Theranostics 2026; 16(16): 9113-9144. doi:10.7150/thno.121239 Full text PDF


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Research Paper Oral inulin prebiotic encapsulating Cortex Fraxini extracellular vesicles alleviates colitis and associated renal stress via reinforcing intestinal barriers and remodeling microbiota Meihong Chai, Junlong Fu, Mengjie Zhang, Xing Pei, Xingzhou Liu, Bing Xiao, Bowen Gao, Jingya Wei, Baosen Yue, Mingxin Zhang, Mingzhen Zhang, Juan Jin Theranostics 2026; 16(16): 9093-9112. doi:10.7150/thno.139484 Full text PDF


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Research Paper Visualizing the distribution of durvalumab targeting PD-L1 using quantitative fluorescence imaging in patients with esophageal cancer Anne M. van der Waaij, Ymke J. van Ginkel, Pia Volkmer, Gursah Kats-Ugurlu, Henrik K. Huizinga, Sara Hone Lopez, Jacco J. de Haan, Rina Bijlsma, Laurens A. van der Waaij, Christina T. Muijs, Anne G.H. Niezink, Boudewijn van Etten, Jessie Westerhof, Massimiliano di Pietro, Dominic J. Robinson, Marjolijn N. Lub-de Hooge, Wouter B. Nagengast Theranostics 2026; 16(16): 9080-9092. doi:10.7150/thno.136523 Full text PDF


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Research Paper mRNA-dendritic cell antigen vaccine potentiates CD38 CAR-T Cell therapy for relapsed/refractory acute myeloid leukemia Yu Lu, Xin Cai, Yanhui Li, Yuyuan Lv, Yutong Tang, Yuanyuan Li, Jiazi Zhou, Ailin Zhang, Pengchen Gu, Ziyi Hao, Qingya Cui, Jianhong Chu, Depei Wu, Xiaowen Tang Theranostics 2026; 16(16): 9061-9079. doi:10.7150/thno.139339 Full text PDF

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Issue 13; 2026

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Founding Editor-in-Chief:
Prof. Xiaoyuan (Shawn) Chen, PhD
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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.



Special Issue - Advanced Cell and Gene Therapy Strategies for Precision Treatment of Autoimmune Diseases. Theme issue editors: Weisheng Guo (Guangzhou Medical University), Xiaoyuan Chen (Shandong Cancer Hospital and Institute).


Visualizing the distribution of durvalumab targeting PD-L1 using quantitative fluorescence imaging in patients with esophageal cancer

Rationale: Immune checkpoint inhibition (ICI) targeting programmed death-1 or its ligand (PD-1/PD-L1) is being explored as an addition to standard treatment for esophageal cancer (EC) to improve response rates, yet robust methods for patient selection are lacking. The predictive value of PD-L1 expression in biopsies is inconsistent due to intra- and intertumoral heterogeneity, and the impact of neoadjuvant chemoradiotherapy (CRT) on ICI response is ...

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