ISSN: 1838-7640Theranostics
Global reach, higher impact
Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.
Research Paper
Intranasal delivery of engineered extracellular vesicles loaded with miR-206-3p antagomir ameliorates Alzheimer's disease phenotypes
Dong Peng, Tingting Liu, Huahui Lu, Lei Zhang, Hongxia Chen, Yadong Huang, Bo Hu, Qihao Zhang
Theranostics 2024; 14(19): 7623-7644. doi:10.7150/thno.103596
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Review
Virus-like particle encapsulation of functional proteins: advances and applications
Xianxun Sun, Yindong Lian, Tao Tian, Zongqiang Cui
Theranostics 2024; 14(19): 7604-7622. doi:10.7150/thno.103127
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Research Paper
A fluorogenic ROS-triggered hydrogen sulfide donor for alleviating cerebral ischemia-reperfusion injury
Huangjie Lu, Huiying Zeng, Wenlong Wei, Yuying Chen, Ziqiang Zhou, Xuyang Ning, Ping Hu
Theranostics 2024; 14(19): 7589-7603. doi:10.7150/thno.100930
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Research Paper
FBLN7 mediates vascular smooth muscle cell phenotype switching and vascular remodeling in hypertension
Guoqing Yao, Xuehui Zheng, Yang Hu, Yuan Zhao, Binghui Kong, Yun Ti, Pei li Bu
Theranostics 2024; 14(19): 7569-7588. doi:10.7150/thno.102593
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Research Paper
Rc3h1 negatively regulates osteoclastogenesis by limiting energy metabolism
Liuyuan Chen, Yuangang Su, Chaofeng Wang, Qian Huang, Weiwei Chen, Na Hai, Jikang Wang, Haoyu Lian, Jinmin Zhao, Jiake Xu, Qian Liu
Theranostics 2024; 14(19): 7554-7568. doi:10.7150/thno.99565
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Research Paper
An enzyme-mimicking reactive oxygen species scavenger targeting oxidative stress-inflammation cycle ameliorates IR-AKI by inhibiting pyruvate dehydrogenase kinase 4
Wenfang He, Chenguang Ding, Ting Lin, Binqi Wang, Wenjing Wang, Zhichao Deng, Taian Jin, Yiwei Shang, Danna Zheng, Ting Bai, Mingzhen Zhang, Runqing Li, Juan Jin, Qiang He
Theranostics 2024; 14(19): 7534-7553. doi:10.7150/thno.101229
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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile
Congratulations! Professor Chen has been elected as a member of the Academia Europaea.
- Theranostics is indexed by Science Citation Index (SCI) and MEDLINE. (Full index information)
- Full texts of articles in PubMed Central and Europe PMC. Abstracts in PubMed.
Proteins face several challenges in biomedicine, including issues with antibody production, degradation by proteases, rapid clearance by the kidneys, and short half-lives. To address these problems, various nano delivery systems have been developed, with virus-like particles (VLPs) emerging as a leading solution. VLPs, which are self-assembled protein complexes, offer effective encapsulation and transport of proteins. They provide enhanced stability, extended circulation time, preserved biological activity, improved targeting for therapies or imaging, and reduced side effects due to minimized systemic....
Rationale: The level of miR-206-3p in the plasma and temporal cortex is increased in Alzheimer's disease (AD) patients. miR-206-3p antagomir injected into hippocampus ameliorates cognitive deficits by enhancing the level of BDNF. However, the trauma caused by brain injection and susceptibility to degradation limit its application. Methods: To overcome these challenges, we constructed engineered extracellular vesicles derived from mesenchymal stem cell (MSC-EVs) loaded with miR-206-3p antagomir (MSC-EVs-anta) by electroporation technology, and explored the therapeutic effects of MSC-EVs-anta delivered....
Nanotheranostics is indexed in MEDLINE and PubMed Central ...
Research Paper
Development and assessment of a novel magnetic nanoparticle antibody-conjugate and aptamer-based assay (MNp-Ab-Ap assay) for the rapid diagnosis of pleural tuberculosis
Pratibha Sharma, Rakesh Kumar Gupta, Simran Aittan, Divya Anthwal, Manisha Dass, Rakesh Yadav, Ashish Behera, Abhijeet Dhiman, Sahajal Dhooria, Sunil Sethi, Ritu Singhal, Puneet Arora, Ashutosh Nath Aggarwal, Tarun Kumar Sharma, Sagarika Haldar
Nanotheranostics 2025; 9(1): 20-30.
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