ISSN: 1838-7640Theranostics
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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.
Review
From biogenesis to aptasensors: advancements in analysis for tumor-derived extracellular vesicles research
Gaojian Yang, Zhiyang Li, Rabia Usman, Yuan Liu, Song Li, Zhu Chen, Hui Chen, Yan Deng, Yile Fang, Nongyue He
Theranostics 2024; 14(10): 4161-4183. doi:10.7150/thno.95885
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Research Paper
FUS-mediated BBB opening leads to transient perfusion decrease and inflammation without acute or chronic brain lesion
Sébastien Rigollet, Claire Rome, Thomas Ador, Erik Dumont, Chantal Pichon, Anthony Delalande, Emmanuel L. Barbier, Vasile Stupar
Theranostics 2024; 14(10): 4147-4160. doi:10.7150/thno.96721
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Review
Biomarker-driven molecular imaging probes in radiotherapy
Haonan Li, Qiyong Gong, Kui Luo
Theranostics 2024; 14(10): 4127-4146. doi:10.7150/thno.97768
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Research Paper
The CEBPB+ glioblastoma subcluster specifically drives the formation of M2 tumor-associated macrophages to promote malignancy growth
Yongchang Yang, Xingyu Jin, Yang Xie, Chunlan Ning, Yiding Ai, Haotian Wei, Xing Xu, Xianglian Ge, Tailong Yi, Qiang Huang, Xuejun Yang, Tao Jiang, Xiaoguang Wang, Yingzhe Piao, Xun Jin
Theranostics 2024; 14(10): 4107-4126. doi:10.7150/thno.93473
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Research Paper
PRMT6-mediated ADMA promotes p62 phase separation to form a negative feedback loop in ferroptosis
Lifeng Feng, Lini Chen, Weikai Wang, Qi Wei, Minqiang Chen, Xin Jiang, Shiman Hu, Yuchen Wu, Lian Duan, Liyuan Zhu, Xian Wang, Hongchuan Jin
Theranostics 2024; 14(10): 4090-4106. doi:10.7150/thno.94789
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Research Paper
Targeted opening of the blood-brain barrier using VCAM-1 functionalised microbubbles and “whole brain” ultrasound
Vanessa A. Johanssen, Jia-Ling Ruan, Oliver Vince, Alec Thomas, Sarah Peeters, Manuel Sarmiento Soto, Jessica Buck, Michael Gray, Eleanor Stride, Nicola R. Sibson
Theranostics 2024; 14(10): 4076-4089. doi:10.7150/thno.93172
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Research Paper
Microglial circ-UBE2K exacerbates depression by regulating parental gene UBE2K via targeting HNRNPU
Yujie Cai, Yao Ji, Yingxuan Liu, Dandan Zhang, Zheng Gong, Li Li, Xiongjin Chen, Chunmei Liang, Sifan Feng, Jiongtong Lu, Qinjie Qiu, Zhixiong Lin, Yan Wang, Lili Cui
Theranostics 2024; 14(10): 4058-4075. doi:10.7150/thno.96890
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Research Paper
Bioinspired soft-hard combined system with mild photothermal therapeutic activity promotes diabetic bone defect healing via synergetic effects of immune activation and angiogenesis
Minhao Wu, Huifan Liu, Yufan Zhu, Ping Wu, Yun Chen, Zhouming Deng, Xiaobin Zhu, Lin Cai
Theranostics 2024; 14(10): 4014-4057. doi:10.7150/thno.97335
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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile
Congratulations! Professor Chen has been elected as a member of the Academia Europaea.
- Theranostics is indexed by Science Citation Index (SCI) and MEDLINE. (Full index information)
- Full texts of articles in PubMed Central and Europe PMC. Abstracts in PubMed.
CFP - Special issue on Molecular Imaging and Theranostics. Guest Editors: Dr. Jianhua Zou, Dr. Jingjing Zhang and Dr. Mengyao Zhao.
Special Issue: Osteoarthritis Theranostics. Guest Editors: Dr. WEN, CHUNYI, Dr. Magali Cucchiarini.
Impact: The permeabilization of the BBB to deliver therapeutics with MR-guided FUS redefines therapeutic strategies as it improves patient outcomes. To ensure the best translation towards clinical treatment, the evaluation of hemodynamic modifications in the CNS is necessary to refine treatment parameters. Methods: MR-guided FUS was applied at 1.5 MHz with a 50 ms burst every 1 s to open the BBB. CBF, BVf and ADC parameters were monitored with MRI. Cavitation was monitored with a PCD during the FUS sequence and classified with the IUD index into three cavitation levels. We distinctly applied the....
Background: Knowledge about the pathogenesis of depression and treatments for this disease are lacking. Epigenetics-related circRNAs are likely involved in the mechanism of depression and have great potential as treatment targets, but their mechanism of action is still unclear. Methods: Circular RNA UBE2K (circ-UBE2K) was screened from peripheral blood of patients with major depressive disorder (MDD) and brain of depression model mice through high-throughput sequencing. Microinjection of circ-UBE2K overexpression lentivirus and adeno-associated virus for interfering with microglial circ-UBE2K into....
Nanotheranostics is indexed in MEDLINE and PubMed Central ...
Research Paper
Neuroprotective Effects of Zinc Oxide Nanoparticles in a Rotenone-Induced Mouse Model of Parkinson's Disease
Yasmeen Khafajah, Mariam Shaheen, Dania El Natour, Maxime Merheb, Rachel Matar, Jamilah Borjac
Nanotheranostics 2024; 8(4): 497-505.
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