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Review GRP78 in human diseases: From molecular chaperone to therapeutic target Full text PDF
Research Paper c-Met-targeted NIR-II imaging for precision management of oral squamous cell carcinoma and premalignant lesions Full text PDF
Research Paper Intermittent hypoxia ameliorates behavioral deficits and exerts neurorestoration in a mouse photothrombotic stroke model Full text PDF
Research Paper A clinically translatable, irreversibly attenuated Salmonella strain as a next-generation adjuvant for checkpoint immunotherapy Full text PDF
Research Paper DKK3–CKAP4 signaling drives fibroimmune remodeling and hair follicle miniaturization in androgenetic alopecia Full text PDF
Research Paper Porphyrin-lipid nanotheranostics for multimodal imaging of nodal disease in preclinical oral cancers Full text PDF
Issue 10; 2026
Founding Editor-in-Chief:
Prof. Xiaoyuan (Shawn) Chen, PhD
Profile
Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.
- Theranostics is indexed by Science Citation Index (SCI) and MEDLINE. (Full index information)
- Full texts of articles in PubMed Central and Europe PMC. Abstracts in PubMed.
- (For NIH-funded researchers) Save time by submitting your paper to us - this journal is in full compliance with NIH Public Access Requirement.
Rationale: The immunosuppressive tumor microenvironment (TME) remains a major barrier to the efficacy of immune checkpoint blockade (ICB) therapy, underscoring the need for strategies that can safely reprogram the TME to enhance cancer immunity. Methods: Here, we developed CNC018, a clinically translatable Salmonella typhimurium (SL) strain designed to reprogram the TME and potentiate responses to ICB. CNC018 was constructed using the ppGpp-defective ...