Theranostics

open access Global reach, higher impact

Research Paper A miniaturized-tumor culture platform for developing anti-tumor immunotherapies Yangyang Feng, Ling Li, Josh Haipeng Lei, Yuzhong Peng, Lijian Wang, Heng Sun, Dongyang Tang, Xinyu Guo, Xiangpeng Chu, Yunfeng Qiao, Kai Miao, Wen-Li Zhu, Chon-Wa Lam, Kin-Iong Chan, Wai-Kuok Chu, Shi-Xian Yao, Wei-Jian Hou, Xiaoling Xu, Zheng Chen, Chu-Xia Deng Theranostics 2026; 16(14): 8129-8150. doi:10.7150/thno.132113 Full text PDF

Research Paper Trop2-targeted PET/CT imaging with ⁶⁸Ga-MY6349 improves diagnostic accuracy and influences clinical management in breast cancer Lingyu Yu, Liang Zhao, Ru Zeng, Yonghui Su, Zhenyu Wu, Shan Yu, Yin Li, Hao Fu, Wei Guo, Yining Sun, Hannan Gao, Long Sun, Hua Wu, Feng Ye, Fan Wang, Haojun Chen Theranostics 2026; 16(14): 8117-8128. doi:10.7150/thno.136704 Full text PDF

Research Paper An engineered ferritin nanocage co-delivery system for targeted hair cells protection and hearing loss attenuation Junying Zhang, Zhiwei Zheng, Jiaru Zhang, Xinyuan Ma, Zihao Li, Hongyan Lin, Guohui Nie, Minmin Liang, Hui Ding, Yingzi He Theranostics 2026; 16(14): 8104-8116. doi:10.7150/thno.131600 Full text PDF

Review Decoding autophagy in neuro-tumor crosstalk: from underlying mechanisms to translational opportunities Huifang Cheng, Hongyao Li, Peiyan Liu, Xin Jin, Yi Qu, Bo Liu, Aizhuo Li Theranostics 2026; 16(14): 8077-8103. doi:10.7150/thno.134896 Full text PDF

Research Paper Endothelial epigenetic senescence driven microglial activation mediates cardio-retinal neuroinflammation in heart failure Mengdan Wang, Shuo Zhang, Tursunjan Aziz, Shiyao Zhang, Xiao Wu, Gang Li, Yan Wang Theranostics 2026; 16(14): 8055-8076. doi:10.7150/thno.136220 Full text PDF

Review Emerging trends in bone marrow organoid research: From hematopoietic microenvironment reconstruction to translational and regenerative theranostic applications Heebin Park, Jaemin Jeong Theranostics 2026; 16(14): 8036-8054. doi:10.7150/thno.137874 Full text PDF

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Issue 12; 2026

Founding Editor-in-Chief:
Prof. Xiaoyuan (Shawn) Chen, PhD
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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Theranostics is indexed by Science Citation Index (SCI) and MEDLINE. (Full index information)
Full texts of articles in PubMed Central and Europe PMC. Abstracts in PubMed.
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A miniaturized-tumor culture platform for developing anti-tumor immunotherapies

Rationale: The preservation of the tumor immune microenvironment (TIME) ex vivo is essential for investigating tumor-immune interactions and developing effective immunotherapies. However, current culture models often fail to maintain autologous immune cells or support high-throughput testing. To overcome these limitations, we establish and validate a novel miniaturized-tumor culture (MTC) platform. Methods: To build the MTC platform, we took tumor ...