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Review Efferocytosis in heart failure: Mechanisms, dysregulation and therapeutic potential Otega Oviri, Shijie Liu, Hongye Huang, Xiaoyuan Bai, Jingke Yao, Zufeng Ding Theranostics 2026; 16(12): 6671-6690. doi:10.7150/thno.132477 Full text PDF


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Review Functionalized metallic nanomaterials, nanozymes and nanomotors for emerging tumor diagnosis and treatment: from design to theranostics strategies Ze Wang, Dongzhou Wang, Bingya Zhang, Tong Sha, Di You, Mikhail I. Voevoda, Guokun Zhang, Bai Yang, Wenlai Guo, Quan Lin, Wenrui Qu Theranostics 2026; 16(12): 6634-6670. doi:10.7150/thno.131873 Full text PDF


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Review Bacterial extracellular vesicles as multifaceted regulators of human diseases and emerging therapeutic platforms Jing Wang, Shuwen Wang, Yanzheng Wang, Ting Zhang, Xu Zhang Theranostics 2026; 16(12): 6600-6633. doi:10.7150/thno.132287 Full text PDF


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Review The CXCR4-targeted theranostics era: a comprehensive review of a decade of progress (2015–2025) Biao Yang, Wenzhu Hu, Xiao Zhang, Yongkang Gai, Rui An, Chunxia Qin, Mengting Li, Xiaoli Lan Theranostics 2026; 16(12): 6576-6599. doi:10.7150/thno.130266 Full text PDF


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Research Paper Mitochondria-targeting organoselenium theranostic radioprotectors for simultaneous treatment and imaging of radiation-induced liver injury Zifei Wu, Xie Huang, Mingquan Gao, Liting Wang, Zaizhi Du, Ziqian Shang, Xudong Yu, Xiaojiao Wang, Shuyue Deng, Xinrui Yang, Binghui Lu, Jing Liu, Weidong Wang, Rong Li, Shenglin Luo Theranostics 2026; 16(12): 6554-6575. doi:10.7150/thno.133714 Full text PDF


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Research Paper A dual functional theranostic microneedle patch for immunomodulation and real time monitoring in diabetic wound therapy Shuai Fan, Junlong Zhong, Yeke Chen, Kang Chen, Zhiming Liu, Xinmin Yang, Wen Tan, Wenlong Tang, Wanhui Zhou, Degui Wu, Jiachao Xiong, Zhenhai Zhou, Fanrong Ai, Kai Cao Theranostics 2026; 16(12): 6529-6553. doi:10.7150/thno.133451 Full text PDF

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Issue 10; 2026

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Founding Editor-in-Chief:
Prof. Xiaoyuan (Shawn) Chen, PhD
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Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.



Mitochondria-targeting organoselenium theranostic radioprotectors for simultaneous treatment and imaging of radiation-induced liver injury

Rationale: Normal liver tissue is vulnerable towards ionizing radiation, which leads to radiation-induced liver injury (RILI) and remains a clinical challenge for treatment. Due to poor tissue targeting, mostly radioprotectors show limited radioprotective effect with a narrow therapeutic window. In this study, we report a series of selenium-substituted heptamethine cyanine derivatives (Se-Cys) as versatile radioprotectors for liver-preferential accumulation, ...

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