ISSN: 1838-7640Theranostics
Global reach, higher impact
Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.
Research Paper
Big data analytics and scRNA-seq in human aortic aneurysms and dissections: role of endothelial MerTK
Shijie Liu, Jinzi Wu, Oishani Banerjee, Bingzhong Xue, Hang Shi, Zufeng Ding
Theranostics 2025; 15(1): 202-215. doi:10.7150/thno.103851
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Research Paper
A H2S-activated NIR-II imaging probe for precise diagnosis and pathological evaluation of colorectal tumor
Yu Ji, Qinxian Huang, Qian Jia, Haohao Yan, Yajing Chi, Yuanyuan Jia, Chaoqiang Qiao, Yanbin Feng, Zuo Yang, Ruili Zhang, Zhongliang Wang
Theranostics 2025; 15(1): 189-201. doi:10.7150/thno.103999
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Review
Metabolism of cancer cells and immune cells in the initiation, progression, and metastasis of cancer
Mingxia Jiang, Huapan Fang, Huayu Tian
Theranostics 2025; 15(1): 155-188. doi:10.7150/thno.103376
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Research Paper
18F-5-fluoro-aminosuberic acid PET/CT imaging of oxidative-stress features during the formation of DEN-induced rat hepatocellular carcinoma
Feng Xiong, Yilin Yang, Zhengru Han, Buchuan Zhang, Kijung Kwak, Pei Wang, Qiaorong Chen, Ziqiang Wang, Jingfei Yang, Xiaoyun Deng, Sijuan Zou, Zhuoli Zhang, Pengtao You, Bo Yu, Xiaohua Zhu
Theranostics 2025; 15(1): 141-154. doi:10.7150/thno.100467
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Review
Optical coherence tomography (OCT) and OCT angiography: Technological development and applications in brain science
Luyao Yang, Pengyu Chen, Xiaofei Wen, Qingliang Zhao
Theranostics 2025; 15(1): 122-140. doi:10.7150/thno.97192
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Research Paper
Development of dual aptamers-functionalized c-MET PROTAC degraders for targeted therapy of osteosarcoma
Xuekun Fu, Jie Huang, Xinxin Chen, Duoli Xie, Hongzhen Chen, Zhijian Liang, Zhuqian Wang, Yiying Liang, Aiping Lu, Chao Liang
Theranostics 2025; 15(1): 103-121. doi:10.7150/thno.99588
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Editor-in-Chief:
Xiaoyuan (Shawn) Chen, PhD
Editor-in-chief profile
Congratulations! Professor Chen has been elected as a member of the Academia Europaea.
- Theranostics is indexed by Science Citation Index (SCI) and MEDLINE. (Full index information)
- Full texts of articles in PubMed Central and Europe PMC. Abstracts in PubMed.
Rationale: Aortic aneurysms and dissections (AAD) cause more than 10,000 deaths in the United States each year. However, there are no medications that can effectively prevent the pathogenesis of AAD. MER proto-oncogene tyrosine kinase (MerTK) is a key receptor for efferocytosis, a process for the clearance of apoptotic cells. Here, we mainly focused on ascending aortic aneurysms and dissections (AAAD) and investigated the role of endothelial MerTK in AAAD progression. Methods: Single-cell RNA sequencing (scRNA-seq) analysis in human AAAD samples and RNA-seq big data analytics, combined with our....
Rationale: Osteosarcoma (OS) is the most common bone malignancy. c-MET is recognized as a therapeutic target. However, traditional c-MET inhibitors show compromised efficacy due to the acquired resistance and side effects. PROTACs targeting c-MET have displayed improved antitumor efficacy by overcoming drug resistance, whereas safety concern caused by lack of tumor-targeting ability is still a pending issue. AS1411 is an aptamer that recognizes and penetrates tumors by targeting nucleolin (NCL) overexpressed on the surface of tumor cells. Since NCL interacts with an E3 ligase MDM2 intracellularly,....
Nanotheranostics is indexed in MEDLINE and PubMed Central ...
Research Paper
Therapeutic Potential of Feline Adipose-Derived Stem Cell Exosomes in the Treatment of Feline Idiopathic Cystitis: A Characterization and Functional Analysis of miRNA Content
Andrea Rubini, Federica Zanotti, Danilo Licastro, Giulia Calogero, Gisella Bettini, Cristiana Piccoli, Giuseppe Rubini, Luca Lovatti, Barbara Zavan
Nanotheranostics 2025; 9(1): 38-51.
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