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Volume 7 (9); 2017

Research Paper

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[177Lu]pentixather: Comprehensive Preclinical Characterization of a First CXCR4-directed Endoradiotherapeutic Agent
Margret Schottelius, Theresa Osl, Andreas Poschenrieder, Frauke Hoffmann, Seval Beykan, Heribert Hänscheid, Andreas Schirbel, Andreas K. Buck, Saskia Kropf, Markus Schwaiger, Ulrich Keller, Michael Lassmann, Hans-Jürgen Wester
Theranostics 2017; 7(9): 2350-2362. doi:10.7150/thno.19119
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Quantification of Tumor Vascular Permeability and Blood Volume by Positron Emission Tomography
Haojun Chen, Xiao Tong, Lixin Lang, Orit Jacobson, Bryant C. Yung, Xiangyu Yang, Ruiliang Bai, Dale O. Kiesewetter, Ying Ma, Hua Wu, Gang Niu, Xiaoyuan Chen
Theranostics 2017; 7(9): 2363-2376. doi:10.7150/thno.19898
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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An [18F]-Positron-Emitting, Fluorescent, Cerebrospinal Fluid Probe for Imaging Damage to the Brain and Spine
Harikrishna Kommidi, Hua Guo, Nandi Chen, Dohyun Kim, Bin He, Amy P. Wu, Omer Aras, Richard Ting
Theranostics 2017; 7(9): 2377-2391. doi:10.7150/thno.19408
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Visualization of Tumor-Immune Interaction - Target-Specific Imaging of S100A8/A9 Reveals Pre-Metastatic Niche Establishment
Michel Eisenblaetter, Fabian Flores-Borja, Jae Jin Lee, Christina Wefers, Hannah Smith, Rebekka Hueting, Margaret S Cooper, Philip J Blower, Dominic Patel, Manuel Rodriguez-Justo, Hanna Milewicz, Thomas Vogl, Johannes Roth, Andrew Tutt, Tobias Schaeffter, Tony Ng
Theranostics 2017; 7(9): 2392-2401. doi:10.7150/thno.17138
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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In-depth Characterization of a TCR-specific Tracer for Sensitive Detection of Tumor-directed Transgenic T Cells by Immuno-PET
Nahid Yusufi, Sabine Mall, Henrique de Oliveira Bianchi, Katja Steiger, Sybille Reder, Richard Klar, Stefan Audehm, Mona Mustafa, Stephan Nekolla, Christian Peschel, Markus Schwaiger, Angela M Krackhardt, Calogero D`Alessandria
Theranostics 2017; 7(9): 2402-2416. doi:10.7150/thno.17994
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Vibrational Profiling of Brain Tumors and Cells
Sultan L Nelson, Dustin T Proctor, Ahmad Ghasemloonia, Sanju Lama, Kourosh Zareinia, Younghee Ahn, Mustafa R Al-Saiedy, Francis HY Green, Matthias W Amrein, Garnette R Sutherland
Theranostics 2017; 7(9): 2417-2430. doi:10.7150/thno.19172
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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3-D Electrochemical Impedance Spectroscopy Mapping of Arteries to Detect Metabolically Active but Angiographically Invisible Atherosclerotic Lesions
René R. Sevag Packard, Yuan Luo, Parinaz Abiri, Nelson Jen, Olcay Aksoy, William M. Suh, Yu-Chong Tai, Tzung K. Hsiai
Theranostics 2017; 7(9): 2431-2442. doi:10.7150/thno.19184
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Gut Microbiota-Mediated Personalized Treatment of Hyperlipidemia Using Berberine
Yan Wang, Qian Tong, Jia-Wen Shou, Zhen-Xiong Zhao, Xiao-Yang Li, Xian-Feng Zhang, Shu-Rong Ma, Chi-Yu He, Yuan Lin, Bao-Ying Wen, Fang Guo, Jie Fu, Jian-Dong Jiang
Theranostics 2017; 7(9): 2443-2451. doi:10.7150/thno.18290
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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miR-196a Enhances Neuronal Morphology through Suppressing RANBP10 to Provide Neuroprotection in Huntington's Disease
Lu-Shiun Her, Su-Han Mao, Chih-Yi Chang, Pei-Hsun Cheng, Yu-Fan Chang, Han-In Yang, Chuan-Mu Chen, Shang-Hsun Yang
Theranostics 2017; 7(9): 2452-2462. doi:10.7150/thno.18813
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Ultrasonographic Imaging and Anti-inflammatory Therapy of Muscle and Tendon Injuries Using Polymer Nanoparticles
Gi-Wook Kim, Changsun Kang, Young-Bin Oh, Myoung-Hwan Ko, Jeong-Hwan Seo, Dongwon Lee
Theranostics 2017; 7(9): 2463-2476. doi:10.7150/thno.18922
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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PSMA-Targeted Theranostic Nanocarrier for Prostate Cancer
Orielyz Flores, Santimukul Santra, Charalambos Kaittanis, Rania Bassiouni, Amr S Khaled, Annette R. Khaled, Jan Grimm, J Manuel Perez
Theranostics 2017; 7(9): 2477-2494. doi:10.7150/thno.18879
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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High-Yield Synthesis of Monomeric LMWP(CPP)-siRNA Covalent Conjugate for Effective Cytosolic Delivery of siRNA
Junxiao Ye, Ergang Liu, Junbo Gong, Jianxin Wang, Yongzhuo Huang, Huining He, Victor C. Yang
Theranostics 2017; 7(9): 2495-2508. doi:10.7150/thno.19863
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Fabrication of Tissue-Engineered Bionic Urethra Using Cell Sheet Technology and Labeling By Ultrasmall Superparamagnetic Iron Oxide for Full-Thickness Urethral Reconstruction
Shukui Zhou, Ranxin Yang, Qingsong Zou, Kaile Zhang, Ting Yin, Weixin Zhao, Joseph G. Shapter, Guo Gao, Qiang Fu
Theranostics 2017; 7(9): 2509-2523. doi:10.7150/thno.18833
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Rapid In Situ MRI Traceable Gel-forming Dual-drug Delivery for Synergistic Therapy of Brain Tumor
Feng-Wei Lin, Pin-Yuan Chen, Kuo-Chen Wei, Chiung-Yin Huang, Chih-Kuang Wang, Hung-Wei Yang
Theranostics 2017; 7(9): 2524-2536. doi:10.7150/thno.19856
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Regulation on Toll-like Receptor 4 and Cell Barrier Function by Rab26 siRNA-loaded DNA Nanovector in Pulmonary Microvascular Endothelial Cells
Hongli Li, Binfeng He, Xueping Liu, Jingtong Li, Qian Liu, Weijie Dong, Zhi Xu, Guisheng Qian, Hua Zuo, Changhua Hu, Hang Qian, Chengde Mao, Guansong Wang
Theranostics 2017; 7(9): 2537-2554. doi:10.7150/thno.17584
[Abstract] [Full text] [PDF] [PubMed] [PMC]