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Theranostics 2024; 14(1):33-55. doi:10.7150/thno.90093 This issue Cite
Review
Tumor-on-a-chip models combined with mini-tissues or organoids for engineering tumor tissues
Department of Precision Medicine, Sungkyunkwan University School of Medicine (SKKU-SOM) Suwon 16419, Republic of Korea
* The authors contributed equally.
Citation:
Hwangbo H, Chae S, Kim W, Jo S, Kim GH. Tumor-on-a-chip models combined with mini-tissues or organoids for engineering tumor tissues. Theranostics 2024; 14(1):33-55. doi:10.7150/thno.90093. https://www.thno.org/v14p0033.htm
Other stylesAbstract
The integration of tumor-on-a-chip technology with mini-tissues or organoids has emerged as a powerful approach in cancer research and drug development. This review provides an extensive examination of the diverse biofabrication methods employed to create mini-tissues, including 3D bioprinting, spheroids, microfluidic systems, and self-assembly techniques using cell-laden hydrogels. Furthermore, it explores various approaches for fabricating organ-on-a-chip platforms. This paper highlights the synergistic potential of combining these technologies to create tumor-on-a-chip models that mimic the complex tumor microenvironment and offer unique insights into cancer biology and therapeutic responses.
Keywords: Tumor-on-a-chip, Tumor microenvironment, Organoids, Biofabrication, Cancer research
Citation styles
APA
Hwangbo, H., Chae, S., Kim, W., Jo, S., Kim, G.H. (2024). Tumor-on-a-chip models combined with mini-tissues or organoids for engineering tumor tissues. Theranostics, 14(1), 33-55. https://doi.org/10.7150/thno.90093.
ACS
Hwangbo, H.; Chae, S.; Kim, W.; Jo, S.; Kim, G.H. Tumor-on-a-chip models combined with mini-tissues or organoids for engineering tumor tissues. Theranostics 2024, 14 (1), 33-55. DOI: 10.7150/thno.90093.
NLM
Hwangbo H, Chae S, Kim W, Jo S, Kim GH. Tumor-on-a-chip models combined with mini-tissues or organoids for engineering tumor tissues. Theranostics 2024; 14(1):33-55. doi:10.7150/thno.90093. https://www.thno.org/v14p0033.htm
CSE
Hwangbo H, Chae S, Kim W, Jo S, Kim GH. 2024. Tumor-on-a-chip models combined with mini-tissues or organoids for engineering tumor tissues. Theranostics. 14(1):33-55.
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