Theranostics 2018; 8(15):4152-4154. doi:10.7150/thno.28368 This issue

Erratum

A smart bilayered scaffold supporting keratinocytes and muscle cells in micro/nano-scale for urethral reconstruction

XiangGuo Lv1*, Chao Feng2*, YiDong Liu1*, XuFeng Peng2, ShiYan Chen3, DongDong Xiao1, HuaPing Wang3, Zhe Li4 Corresponding address, YueMin Xu2 Corresponding address, MuJun Lu1 Corresponding address

1. Department of Urology and Andrology, Shanghai Renji Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China;
2. Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China;
3. State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, China;
4. College of Materials and Textile Engineering, JiaXing University, Zhejiang, China.
*Co-first author: These authors contributed equally to the work

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
Citation:
Lv X, Feng C, Liu Y, Peng X, Chen S, Xiao D, Wang H, Li Z, Xu Y, Lu M. A smart bilayered scaffold supporting keratinocytes and muscle cells in micro/nano-scale for urethral reconstruction. Theranostics 2018; 8(15):4152-4154. doi:10.7150/thno.28368. Available from https://www.thno.org/v08p4152.htm

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Corrected-article in Theranostics, Volume 8, 3153

Erratum 1

In our paper [1], Figure 5 and Figure 6 should be corrected as follows.

 Figure 5 

(A-F) During the surgical procedure in a dog model, the urethra between the bladder and the pubic symphysis was exposed, and a 5 cm long urethra section was transected and removed. Then, the scaffold was sutured onto the urethral defect. (G-L) Comparison of urethrography images in each group at 3 and 6 months after operation. The arrow indicates the urethroplasty site of the urethra.

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 Figure 6 

Histologic analysis of reconstructed urethras at 3 and 6 months post-implantation. Evaluation of epithelium, smooth muscle and vessels with AE1/AE3, desmin and CD31 immunohistochemical (IHC) staining in the retrieved urethra; H&E: hematoxylin and eosin.

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Erratum 2

Sentence of page 3156:

“After the urethral caliber was assessed with retrograde urethrograms, five animals from each group were killed at one and three months post-implantation.”.

should be modified to be:

“"After the urethral caliber was assessed with retrograde urethrograms, five animals from each group were killed at three and six months post-implantation".

Erratum 3

Sentence of page 3159:

“At 1 month, retrograde urethrograms showed a wide urethral caliber without a fistula or stricture in group A (Fig. 5 G). However, group B revealed mild strictures in all dogs, and bladder distension occurred after catheter removal in 3 dogs at 1 month (Fig. 5 I).

At 3 months, retrograde urethrography revealed the maintenance of a wide urethral caliber without any sign of strictures in group A (Fig. 5 H).

Histological assays were performed on all groups at 1 and 3 months post-operation. At 1 month, all canines in group A had intact epithelial cellular layers: 2-3 layers of well-developed, stratified epithelium (Fig. 6 A, C) and increased numbers of organized muscle bundles were observed (Fig. 6 B, D). At 1 and 3 months, a large amount of new growth vascular formation was observed in groups A and B (Fig. 6 E, J, O, T).”

should be modified to be:

" At 3 month, retrograde urethrograms showed a wide urethral caliber without a fistula or stricture in group A (Fig. 5 G). However, group B revealed mild strictures in all dogs, and bladder distension occurred after catheter removal in 3 dogs at 3 month (Fig. 5 I).

At 6 months, retrograde urethrography revealed the maintenance of a wide urethral caliber without any sign of strictures in group A (Fig. 5 H).

Histological assays were performed on all groups at 3 and 6 months post-operation. At 3 month, all canines in group A had intact epithelial cellular layers: 2-3 layers of well-developed, stratified epithelium (Fig. 6 A, C) and increased numbers of organized muscle bundles were observed (Fig. 6 B, D). At 3 and 6 months, a large amount of new growth vascular formation was observed in groups A and B (Fig. 6 E, J, O, T).".

References

1. Lv X, Feng C, Liu Y. et al. A smart bilayered scaffold supporting keratinocytes and muscle cells in micro/nano-scale for urethral reconstruction. Theranostics. 2018;8(11):3153-63 doi: 10.7150/thno.22080

Author contact

Corresponding address Corresponding author: MuJun Lu MD. PhD; E-mail: lumujuncom; Zhe Li PhD; E-mail: lizhe830817com; YueMin Xu MD. PhD; E-mail: xuyueminnet


Published 2018-7-27