Targeted Nanoprobes Reveal Early Time Point Kinetics <i>In Vivo</i> by Time-Resolved MRI

Bhirde, Ashwinkumar; Guo, Ning; Chen, Xiaoyuan

doi:10.7150/thno/v01p0274

Nanotheranostics

International Journal of Biological Sciences

International Journal of Medical Sciences

Journal of Cancer

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Theranostics 2011; 1:274-276. doi:10.7150/thno/v01p0274 This volume Cite

Commentary

Targeted Nanoprobes Reveal Early Time Point Kinetics In Vivo by Time-Resolved MRI

Ashwinkumar Bhirde, Ning Guo, Xiaoyuan Chen^✉

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, Maryland 20892

Citation:

Bhirde A, Guo N, Chen X. Targeted Nanoprobes Reveal Early Time Point Kinetics In Vivo by Time-Resolved MRI. Theranostics 2011; 1:274-276. doi:10.7150/thno/v01p0274. https://www.thno.org/v01p0274.htm

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Abstract

This commentary highlights the findings by Kessinger et al. (Theranostics 2011; 1: 263-275) that dynamic T₂*-weighted magnetic resonance imaging (MRI) of cyclic RGD peptide-encoded superparamagnetic polymeric micelle (SPPM) nanoparticles allows quantitative analysis of tumor integrin αvβ3 expression, which can exclude the effect of blood volume and extravascular signal components and thus provide less biased tumor contrast and receptor specificity of probes.

Keywords: Commentary, Superparamagnetic Nanoparticles, Integrin, Cyclic RGD Peptide, Dynamic MRI.

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APA

Bhirde, A., Guo, N., Chen, X. (2011). Targeted Nanoprobes Reveal Early Time Point Kinetics In Vivo by Time-Resolved MRI. Theranostics, 1, 274-276. https://doi.org/10.7150/thno/v01p0274.

ACS

Bhirde, A.; Guo, N.; Chen, X. Targeted Nanoprobes Reveal Early Time Point Kinetics In Vivo by Time-Resolved MRI. Theranostics 2011, 1, 274-276. DOI: 10.7150/thno/v01p0274.

NLM

CSE

Bhirde A, Guo N, Chen X. 2011. Targeted Nanoprobes Reveal Early Time Point Kinetics In Vivo by Time-Resolved MRI. Theranostics. 1:274-276.

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