Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Research Paper
Reconstituting gut microbiota-colonocyte interactions reverses diet-induced cognitive deficits: The beneficial of eucommiae cortex polysaccharides
Mengli Wang, Penghao Sun, Xuejun Chai, Yong-Xin Liu, Luqi Li, Wei Zheng, Shulin Chen, Xiaoyan Zhu, Shanting Zhao
Theranostics 2024; 14(12): 4622-4642. doi:10.7150/thno.99468
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Review
Exosome-like nanoparticles derived from fruits, vegetables, and herbs: innovative strategies of therapeutic and drug delivery
Bo Zhao, Hangjuan Lin, Xinchi Jiang, Wanshu Li, Yuli Gao, Minghui Li, Yanan Yu, Ninggang Chen, Jianqing Gao
Theranostics 2024; 14(12): 4598-4621. doi:10.7150/thno.97096
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Research Paper
In-depth cross-validation of human and mouse CD4-specific minibodies for noninvasive PET imaging of CD4⁺ cells and response prediction to cancer immunotherapy
Stefania Pezzana, Simone Blaess, Jule Kortendieck, Nicole Hemmer, Bredi Tako, Claudia Pietura, Lara Ruoff, Simon Riel, Martin Schaller, Irene Gonzalez-Menendez, Leticia Quintanilla-Martinez, Alessandro Mascioni, Argin Aivazian, Ian Wilson, Andreas Maurer, Bernd J. Pichler, Manfred Kneilling, Dominik Sonanini
Theranostics 2024; 14(12): 4582-4597. doi:10.7150/thno.95173
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Research Paper
A novel assessment of whole-mount Gleason grading in prostate cancer to identify candidates for radical prostatectomy: a machine learning-based multiomics study
Jing Ning, Clemens P. Spielvogel, David Haberl, Karolina Trachtova, Stefan Stoiber, Sazan Rasul, Vojtech Bystry, Gabriel Wasinger, Pascal Baltzer, Elisabeth Gurnhofer, Gerald Timelthaler, Michaela Schlederer, Laszlo Papp, Helga Schachner, Thomas Helbich, Markus Hartenbach, Bernhard Grubmüller, Shahrokh F Shariat, Marcus Hacker, Alexander Haug, Lukas Kenner
Theranostics 2024; 14(12): 4570-4581. doi:10.7150/thno.96921
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Research Paper
Impact of TP53 loss-of-function alterations on the response to PSMA radioligand therapy in metastatic castration-resistant prostate cancer patients
Peter H.J. Slootbeek, María Victoria Luna-Velez, Bastiaan M. Privé, Maarten J. van der Doelen, Iris S.H. Kloots, Samhita Pamidimarri Naga, Hilde E. Onstenk, James Nagarajah, Harm Westdorp, Inge M. van Oort, Leonie I. Kroeze, Jack. A. Schalken, Haiko J. Bloemendal, Niven Mehra
Theranostics 2024; 14(12): 4555-4569. doi:10.7150/thno.96322
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Research Paper
ISG15 accelerates acute kidney injury and the subsequent AKI-to-CKD transition by promoting TGFβR1 ISGylation
Na Cui, Chengyu Liu, Xiang Tang, Liangliang Song, Zixuan Xiao, Chen Wang, Yancai Wu, Yihao Zhou, Chentai Peng, Yuxia Liu, Ling Zheng, Xinran Liu, Kun Huang, Hong Chen
Theranostics 2024; 14(11): 4536-4553. doi:10.7150/thno.95796
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Research Paper
Transcranial blood-brain barrier opening in Alzheimer's disease patients using a portable focused ultrasound system with real-time 2-D cavitation mapping
Sua Bae, Keyu Liu, Antonios N. Pouliopoulos, Robin Ji, Sergio Jiménez-Gambín, Omid Yousefian, Alina R. Kline-Schoder, Alec J. Batts, Fotios N. Tsitsos, Danae Kokossis, Akiva Mintz, Lawrence S. Honig, Elisa E. Konofagou
Theranostics 2024; 14(11): 4519-4535. doi:10.7150/thno.94206
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Research Paper
Rbm24/Notch1 signaling regulates adult neurogenesis in the subventricular zone and mediates Parkinson-associated olfactory dysfunction
Ke Wang, Xing-Yang Liu, Sui-Feng Liu, Xiao-Xia Wang, Yi-Hua Wei, Jun-Rong Zhu, Jing Liu, Xiu Qin Xu, Lei Wen
Theranostics 2024; 14(11): 4499-4518. doi:10.7150/thno.96045
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