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Volume 5 (12); 2015

Research Paper

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First-in-human uPAR PET: Imaging of Cancer Aggressiveness
Morten Persson, Dorthe Skovgaard, Malene Brandt-Larsen, Camilla Christensen, Jacob Madsen, Carsten H. Nielsen, Tine Thurison, Thomas Levin Klausen, Søren Holm, Annika Loft, Anne Kiil Berthelsen, Michael Ploug, Helle Pappot, Klaus Brasso, Niels Kroman, Liselotte Højgaard, Andreas Kjaer
Theranostics 2015; 5(12): 1303-1316. doi:10.7150/thno.12956
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study
Ashley F. Stein-Merlob, Chase W. Kessinger, S. Sibel Erdem, Henry Zelada, Scott A. Hilderbrand, Charles P. Lin, Guillermo J. Tearney, Michael R. Jaff, Guy L. Reed, Peter K. Henke, Jason R. McCarthy, Farouc A. Jaffer
Theranostics 2015; 5(12): 1317-1327. doi:10.7150/thno.12494
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Salmonella typhimurium Suppresses Tumor Growth via the Pro-Inflammatory Cytokine Interleukin-1β
Jung-Eun Kim, Thuy Xuan Phan, Vu Hong Nguyen, Hong-Van Dinh-Vu, Jin Hai Zheng, Misun Yun, Sung-Gyoo Park, Yeongjin Hong, Hyon E. Choy, Michael Szardenings, Won Hwang, Jin-A Park, SunHee Park, Sin-Hyeog Im, Jung-Joon Min
Theranostics 2015; 5(12): 1328-1342. doi:10.7150/thno.11432
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Blockade of Interplay between IL-17A and Endoplasmic Reticulum Stress Attenuates LPS-Induced Lung Injury
So Ri Kim, Hee Jung Kim, Dong Im Kim, Kyung Bae Lee, Hae Jin Park, Jae Seok Jeong, Seong Ho Cho, Yong Chul Lee
Theranostics 2015; 5(12): 1343-1362. doi:10.7150/thno.11685
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Interplay of Oxidative Stress and Autophagy in PAMAM Dendrimers-Induced Neuronal Cell Death
Yubin Li, Haiyan Zhu, Shaofei Wang, Xiaolu Qian, Jiajun Fan, Ziyu Wang, Ping Song, Xuesai Zhang, Weiyue Lu, Dianwen Ju
Theranostics 2015; 5(12): 1363-1377. doi:10.7150/thno.13181
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Ultrasound Targeted Microbubble Destruction-Mediated Delivery of a Transcription Factor Decoy Inhibits STAT3 Signaling and Tumor Growth
Jonathan A. Kopechek, Andrew R. Carson, Charles F. McTiernan, Xucai Chen, Bima Hasjim, Linda Lavery, Malabika Sen, Jennifer R. Grandis, Flordeliza S. Villanueva
Theranostics 2015; 5(12): 1378-1387. doi:10.7150/thno.12822
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Echogenic Glycol Chitosan Nanoparticles for Ultrasound-Triggered Cancer Theranostics
Hyun Su Min, Dong Gil You, Sejin Son, Sangmin Jeon, Jae Hyung Park, Seulki Lee, Ick Chan Kwon, Kwangmeyung Kim
Theranostics 2015; 5(12): 1402-1418. doi:10.7150/thno.13099
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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High Efficiency Molecular Delivery with Sequential Low-Energy Sonoporation Bursts
Kang-Ho Song, Alexander C. Fan, John T. Brlansky, Tammy Trudeau, Arthur Gutierrez-Hartmann, Michael L. Calvisi, Mark A. Borden
Theranostics 2015; 5(12): 1419-1427. doi:10.7150/thno.13033
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Phototheranostic Porphyrin Nanoparticles Enable Visualization and Targeted Treatment of Head and Neck Cancer in Clinically Relevant Models
Nidal Muhanna, Cheng S Jin, Elizabeth Huynh, Harley Chan, Yi Qiu, Wenlei Jiang, Liyang Cui, Laura Burgess, Margarete K Akens, Juan Chen, Jonathan C Irish, Gang Zheng
Theranostics 2015; 5(12): 1428-1443. doi:10.7150/thno.13451
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Noninvasive Dynamic Imaging of Tumor Early Response to Nanoparticle-mediated Photothermal Therapy
Fan Zhang, Jianbo Cao, Xiao Chen, Kai Yang, Lei Zhu, Guifeng Fu, Xinglu Huang, Xiaoyuan Chen
Theranostics 2015; 5(12): 1444-1455. doi:10.7150/thno.13398
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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EpCAM Aptamer-mediated Survivin Silencing Sensitized Cancer Stem Cells to Doxorubicin in a Breast Cancer Model
Tao Wang, Michael P. Gantier, Dongxi Xiang, Andrew G Bean, Matthew Bruce, Shu-Feng Zhou, Mustafa Khasraw, Alister Ward, Li Wang, Ming Q. Wei, Hadi AlShamaileh, Lijue Chen, Xiaodong She, Jia Lin, Lingxue Kong, Sarah Shigdar, Wei Duan
Theranostics 2015; 5(12): 1456-1472. doi:10.7150/thno.11692
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

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PSMA Ligands for Radionuclide Imaging and Therapy of Prostate Cancer: Clinical Status
Susanne Lütje, Sandra Heskamp, Alexander S. Cornelissen, Thorsten D. Poeppel, Sebastiaan A. M. W. van den Broek, Sandra Rosenbaum-Krumme, Andreas Bockisch, Martin Gotthardt, Mark Rijpkema, Otto C. Boerman
Theranostics 2015; 5(12): 1388-1401. doi:10.7150/thno.13348
[Abstract] [Full text] [PDF] [PubMed] [PMC]