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Volume 9 (13); 2019

Research Papers

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Theranostic application of lipiodol for transarterial chemoembolization in a VX2 rabbit liver tumor model
Johanna Maria Mijntje van Breugel, Jean-François Geschwind, Sahar Mirpour, Lynn Jeanette Savic, Xuchen Zhang, Rafael Duran, MingDe Lin, Milena Miszczuk, Eleni Liapi, Julius Chapiro
Theranostics 2019; 9(13): 3674-3686. doi:10.7150/thno.32943
[Abstract] [Full text] [PDF]


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Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy
Lang Hu, Mingge Ding, Daishi Tang, Erhe Gao, Congye Li, Kaiyan Wang, Bingchao Qi, Jihuan Qiu, Huishou Zhao, Pan Chang, Feng Fu, Yan Li
Theranostics 2019; 9(13): 3687-3706. doi:10.7150/thno.33684
[Abstract] [Full text] [PDF]


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Nerve modulation therapy in gouty arthritis: targeting increased sFRP2 expression in dorsal root ganglion regulates macrophage polarization and alleviates endothelial damage
Jingtian Mei, Feng Zhou, Han Qiao, Hanjun Li, Tingting Tang
Theranostics 2019; 9(13): 3707-3722. doi:10.7150/thno.33908
[Abstract] [Full text] [PDF]


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One-step colorimetric genotyping of single nucleotide polymorphism using probe-enhanced loop-mediated isothermal amplification (PE-LAMP)
Sheng Ding, Rong Chen, Gangyi Chen, Mei Li, Jiayu Wang, Jiawei Zou, Feng Du, Juan Dong, Xin Cui, Xin Huang, Yun Deng, Zhuo Tang
Theranostics 2019; 9(13): 3723-3731. doi:10.7150/thno.33980
[Abstract] [Full text] [PDF]


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A Multifunctional Nanotherapy for Targeted Treatment of Colon Cancer by Simultaneously Regulating Tumor Microenvironment
Qixiong Zhang, Fuzhong Zhang, Shanshan Li, Renfeng Liu, Taotao Jin, Yin Dou, Zhenhua Zhou, Jianxiang Zhang
Theranostics 2019; 9(13): 3732-3753. doi:10.7150/thno.34377
[Abstract] [Full text] [PDF]


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Repeated ultrasound treatment of tau transgenic mice clears neuronal tau by autophagy and improves behavioral functions
Rucha Pandit, Gerhard Leinenga, Jürgen Götz
Theranostics 2019; 9(13): 3754-3767. doi:10.7150/thno.34388
[Abstract] [Full text] [PDF]


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Melatonin enhances sorafenib-induced cytotoxicity in FLT3-ITD acute myeloid leukemia cells by redox modification
Tian Tian, Jiajun Li, Yizhuo Li, Yun-Xin Lu, Yan-Lai Tang, Hua Wang, Fufu Zheng, Dingbo Shi, Qian Long, Miao Chen, Guillermo Garcia-Manero, Yumin Hu, Lijun Qin, Wuguo Deng
Theranostics 2019; 9(13): 3768-3779. doi:10.7150/thno.34327
[Abstract] [Full text] [PDF]


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Circulating miR-338 Cluster activities on osteoblast differentiation: Potential Diagnostic and Therapeutic Targets for Postmenopausal Osteoporosis
Chujiao Lin, Shuaitong Yu, Runze Jin, Yao Xiao, Minghui Pan, Fei Pei, Xiaojing Zhu, Huarong Huang, Zunyi Zhang, Shuo Chen, Huan Liu, Zhi Chen
Theranostics 2019; 9(13): 3780-3797. doi:10.7150/thno.34493
[Abstract] [Full text] [PDF]


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IL-21-based therapies induce clearance of hepatitis B virus persistence in mouse models
Zhongliang Shen, Jing Liu, Jingwen Wu, Yuanfei Zhu, Gaiyun Li, Jun Wang, Mengjun Luo, Qiang Deng, Jiming Zhang, Youhua Xie
Theranostics 2019; 9(13): 3798-3811. doi:10.7150/thno.35331
[Abstract] [Full text] [PDF]


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Development of a stem cell tracking platform for ophthalmic applications using ultrasound and photoacoustic imaging
Kelsey P. Kubelick, Eric J. Snider, C. Ross Ethier, Stanislav Emelianov
Theranostics 2019; 9(13): 3812-3824. doi:10.7150/thno.32546
[Abstract] [Full text] [PDF]


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pH- and photothermal-driven multistage delivery nanoplatform for overcoming cancer drug resistance
Wenjing Huang, Hao Zhao, Jiangshan Wan, Yang Zhou, Qingbo Xu, Yanbing Zhao, Xiangliang Yang, Lu Gan
Theranostics 2019; 9(13): 3825-3839. doi:10.7150/thno.33958
[Abstract] [Full text] [PDF]


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Suppression of YAP/TAZ-Notch1-NICD axis by bromodomain and extraterminal protein inhibition impairs liver regeneration
Chen Liu, Xiawei Cheng, Juntao Chen, Yao Wang, Xiaoying Wu, Rui Tian, Baoqing Liu, Xianfeng Ding, Qiming Sun, Weihua Gong
Theranostics 2019; 9(13): 3840-3852. doi:10.7150/thno.33370
[Abstract] [Full text] [PDF]


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The m6A demethylase ALKBH5 controls trophoblast invasion at the maternal-fetal interface by regulating the stability of CYR61 mRNA
Xiao-Cui Li, Feng Jin, Bei-Ying Wang, Xiang-Jie Yin, Wei Hong, Fu-Ju Tian
Theranostics 2019; 9(13): 3853-3865. doi:10.7150/thno.31868
[Abstract] [Full text] [PDF]


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Polydopamine coated multifunctional lanthanide theranostic agent for vascular malformation and tumor vessel imaging beyond 1500 nm and imaging-guided photothermal therapy
Xiaolong Li, Mingyang Jiang, Songjun Zeng, Hongrong Liu
Theranostics 2019; 9(13): 3866-3878. doi:10.7150/thno.31864
[Abstract] [Full text] [PDF]


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Forkhead box K2 promotes human colorectal cancer metastasis by upregulating ZEB1 and EGFR
Feng Du, Chenyang Qiao, Xiaowei Li, Zhangqian Chen, Hao liu, Shengda Wu, Sijun Hu, Zhaoyan Qiu, Meirui Qian, Dean Tian, Kaichun Wu, Daiming Fan, Yongzhan Nie, Limin Xia
Theranostics 2019; 9(13): 3879-3902. doi:10.7150/thno.31716
[Abstract] [Full text] [PDF]


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Cysteine-type cathepsins promote the effector phase of acute cutaneous delayed-type hypersensitivity reactions
Johannes Schwenck, Andreas Maurer, Birgit Fehrenbacher, Roman Mehling, Philipp Knopf, Natalie Mucha, Dennis Haupt, Kerstin Fuchs, Christoph M. Griessinger, Daniel Bukala, Julia Holstein, Martin Schaller, Irene Gonzalez Menendez, Kamran Ghoreschi, Leticia Quintanilla-Martinez, Michael Gütschow, Stefan Laufer, Thomas Reinheckel, Martin Röcken, Hubert Kalbacher, Bernd J Pichler, Manfred Kneilling
Theranostics 2019; 9(13): 3903-3917. doi:10.7150/thno.31037
[Abstract] [Full text] [PDF]


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Temporal inhibition of mouse mammary gland cancer metastasis by CORM-A1 and DETA/NO combination therapy
Kseniia Porshneva, Diana Papiernik, Mateusz Psurski, Agnieszka Łupicka-Słowik, Rafał Matkowski, Marcin Ekiert, Marcin Nowak, Joanna Jarosz, Joanna Banach, Magdalena Milczarek, Tomasz M. Goszczyński, Marcin Sieńczyk, Joanna Wietrzyk
Theranostics 2019; 9(13): 3918-3939. doi:10.7150/thno.31461
[Abstract] [Full text] [PDF]


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Clathrin-mediated Endocytosis of Alpha-1 Antitrypsin is Essential for its Protective Function in Islet Cell Survival
Jingjing Wang, Wenyu Gou, Do-sung Kim, Charlie Strange, Hongjun Wang
Theranostics 2019; 9(13): 3940-3951. doi:10.7150/thno.31647
[Abstract] [Full text] [PDF]


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Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome
Dapeng Hao, Jingjing Li, Jianlin Wang, Yuan Meng, Zhiqiang Zhao, Chao Zhang, Kai Miao, Chuxia Deng, Benjamin K. Tsang, Li Wang, Li-jun Di
Theranostics 2019; 9(13): 3952-3965. doi:10.7150/thno.30814
[Abstract] [Full text] [PDF]


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Engineering temperature-sensitive plateletsomes as a tailored chemotherapy platform in combination with HIFU ablation for cancer treatment
Dongqi Wu, Xing Jin, Xiaobing Wang, Boyu Ma, Chenmei Lou, Haijing Qu, Jian Zheng, Binxuan Zhang, Xiufeng Yan, Yang Wang, Lijia Jing
Theranostics 2019; 9(13): 3966-3979. doi:10.7150/thno.32172
[Abstract] [Full text] [PDF]