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Volume 8 (14); 2018

Editorials

Oxygenating the way for enhanced chemophototherapy
Wen Jiang, Ian Michael Delahunty, Jin Xie
Theranostics 2018; 8(14): 3870-3871. doi:10.7150/thno.27810
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Drug nanorods are potential new nanocarriers for intracellular protein delivery
Weiping Gao, Mengmeng Sun
Theranostics 2018; 8(14): 3872-3873. doi:10.7150/thno.27815
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Microvesicles and ectosomes in angiogenesis and diabetes - message in a bottle in the vascular ocean
Michael Lichtenauer, Christian Jung
Theranostics 2018; 8(14): 3974-3976. doi:10.7150/thno.27154
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Papers

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Suspension state promotes metastasis of breast cancer cells by up-regulating cyclooxygenase-2
Xiaomei Zhang, Li Yang, Shu Chien, Yonggang Lv
Theranostics 2018; 8(14): 3722-3736. doi:10.7150/thno.25434
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Blocking CDK1/PDK1/β-Catenin signaling by CDK1 inhibitor RO3306 increased the efficacy of sorafenib treatment by targeting cancer stem cells in a preclinical model of hepatocellular carcinoma
Chuan Xing Wu, Xiao Qi Wang, Siu Ho Chok, Kwan Man, Simon Hing Yin Tsang, Albert Chi Yan Chan, Ka Wing Ma, Wei Xia, Tan To Cheung
Theranostics 2018; 8(14): 3737-3750. doi:10.7150/thno.25487
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Identification and Functional Characterization of Long Non-coding RNA MIR22HG as a Tumor Suppressor for Hepatocellular Carcinoma
Dong-Yan Zhang, Xue-Jing Zou, Chuan-Hui Cao, Ting Zhang, Ling Lei, Xiao-Long Qi, Li Liu, De-Hua Wu
Theranostics 2018; 8(14): 3751-3765. doi:10.7150/thno.22493
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Molecular signatures of liver dysfunction are distinct in fungal and bacterial infections in mice
Barbara Schaarschmidt, Sebastian Vlaic, Anna Medyukhina, Sophie Neugebauer, Sandor Nietzsche, Falk A. Gonnert, Jürgen Rödel, Mervyn Singer, Michael Kiehntopf, Marc Thilo Figge, Ilse D. Jacobsen, Michael Bauer, Adrian T. Press
Theranostics 2018; 8(14): 3766-3780. doi:10.7150/thno.24333
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Nano-delivery of fraxinellone remodels tumor microenvironment and facilitates therapeutic vaccination in desmoplastic melanoma
Lin Hou, Qi Liu, Limei Shen, Yun Liu, Xueqiong Zhang, Fengqian Chen, Leaf Huang
Theranostics 2018; 8(14): 3781-3796. doi:10.7150/thno.24821
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Development of Paper-Based Analytical Devices for Minimizing the Viscosity Effect in Human Saliva
Julaluk Noiphung, Michael P. Nguyen, Chamindie Punyadeera, Yunxia Wan, Wanida Laiwattanapaisal, Charles S. Henry
Theranostics 2018; 8(14): 3797-3807. doi:10.7150/thno.24941
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Self-assembled dual fluorescence nanoparticles for CD44-targeted delivery of anti-miR-27a in liver cancer theranostics
Xiao Zheng, Fan Zhang, Yawei Zhao, Jing Zhang, Jianati Dawulieti, Yue Pan, Lianzhi Cui, Madi Sun, Dan Shao, Mingqiang Li, Kan He, Ming Zhang, Jing Li, Li Chen
Theranostics 2018; 8(14): 3808-3823. doi:10.7150/thno.25255
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Targeting S1PR1/STAT3 loop abrogates desmoplasia and chemosensitizes pancreatic cancer to gemcitabine
Manendra Babu Lankadasari, Jayasekharan S. Aparna, Sabira Mohammed, Shirley James, Kazunori Aoki, Valsalakumari S. Binu, Sindhu Nair, Kuzhuvelil B. Harikumar
Theranostics 2018; 8(14): 3824-3840. doi:10.7150/thno.25308
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling
Yu-Syuan Chen, Ching-Wen Chang, Yeou-Guang Tsay, Liu-Ying Huang, Yi-Chen Wu, Li-Hao Cheng, Cheng-Chieh Yang, Cheng-Hsien Wu, Wan-Huai Teo, Kai-Feng Hung, Chih-Yang Huang, Te-Chang Lee, Jeng-Fan Lo
Theranostics 2018; 8(14): 3841-3855. doi:10.7150/thno.25784
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors
Diego Sanchez-Martinez, Nerea Allende-Vega, Stefania Orecchioni, Giovanna Talarico, Amelie Cornillon, Dang-Nghiem Vo, Celine Rene, Zhao-Yang Lu, Ewelina Krzywinska, Alberto Anel, Eva M. Galvez, Julian Pardo, Bruno Robert, Pierre Martineau, Yosr Hicheri, Francesco Bertolini, Guillaume Cartron, Martin Villalba
Theranostics 2018; 8(14): 3856-3869. doi:10.7150/thno.25149
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Circulating ectosomes: Determination of angiogenic microRNAs in type 2 diabetes
Ewa Ł. Stępień, Martyna Durak-Kozica, Agnieszka Kamińska, Marta Targosz-Korecka, Marcin Libera, Grzegorz Tylko, Agnieszka Opalińska, Maria Kapusta, Bogdan Solnica, Adriana Georgescu, Marina C. Costa, Agnieszka Czyżewska-Buczyńska, Wojciech Witkiewicz, Maciej T. Małecki, Francisco J. Enguita
Theranostics 2018; 8(14): 3874-3890. doi:10.7150/thno.23334
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Tumor-suppressing miR-141 gene complex-loaded tissue-adhesive glue for the locoregional treatment of hepatocellular carcinoma
Min-Kyoung Kim, Young-Ah Moon, Chung Kil Song, Rengarajan Baskaran, Sijeong Bae, Su-Geun Yang
Theranostics 2018; 8(14): 3891-3901. doi:10.7150/thno.24056
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Profiling the circulating miRnome reveals a temporal regulation of the bone injury response
Andreia M. Silva, Maria I. Almeida, José H. Teixeira, Cristina Ivan, Joana Oliveira, Daniel Vasconcelos, Nuno Neves, Cláudia Ribeiro-Machado, Carla Cunha, Mário A. Barbosa, George A. Calin, Susana G. Santos
Theranostics 2018; 8(14): 3902-3917. doi:10.7150/thno.24444
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19
Jing Ren, Liang Ding, Dongya Zhang, Guoping Shi, Qianyun Xu, Sunan Shen, Yaping Wang, Tingting Wang, Yayi Hou
Theranostics 2018; 8(14): 3932-3948. doi:10.7150/thno.25541
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Polylactide-tethered prodrugs in polymeric nanoparticles as reliable nanomedicines for the efficient eradication of patient-derived hepatocellular carcinoma
Hangxiang Wang, Liqian Zhou, Ke Xie, Jiaping Wu, Penghong Song, Haiyang Xie, Lin Zhou, Jialin Liu, Xiao Xu, Youqing Shen, Shusen Zheng
Theranostics 2018; 8(14): 3949-3963. doi:10.7150/thno.26161
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Development of an in vitro cell-sheet cancer model for chemotherapeutic screening
Jaewang Lee, Daiha Shin, Jong-Lyel Roh
Theranostics 2018; 8(14): 3964-3973. doi:10.7150/thno.26439
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The S100A4 Protein Signals through the ErbB4 Receptor to Promote Neuronal Survival
Stanislava Pankratova, Jorg Klingelhofer, Oksana Dmytriyeva, Sylwia Owczarek, Alexander Renziehausen, Nelofer Syed, Alexandra E. Porter, David T. Dexter, Darya Kiryushko
Theranostics 2018; 8(14): 3977-3990. doi:10.7150/thno.22274
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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[18F]fluoroethyltyrosine-induced Cerenkov Luminescence Improves Image-Guided Surgical Resection of Glioma
David Y. Lewis, Richard Mair, Alan Wright, Kieren Allinson, Scott K. Lyons, Tom Booth, Julia Jones, Robert Bielik, Dmitry Soloviev, Kevin M. Brindle
Theranostics 2018; 8(14): 3991-4002. doi:10.7150/thno.23709
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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circEPSTI1 as a Prognostic Marker and Mediator of Triple-Negative Breast Cancer Progression
Bo Chen, Weidong Wei, Xiaojia Huang, Xinhua Xie, Yanan Kong, Danian Dai, Lu Yang, Jin Wang, Hailin Tang, Xiaoming Xie
Theranostics 2018; 8(14): 4003-4015. doi:10.7150/thno.24106
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

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[18F]Tetrafluoroborate ([18F]TFB) and its analogs for PET imaging of the sodium/iodide symporter
Huailei Jiang, Timothy R. DeGrado
Theranostics 2018; 8(14): 3918-3931. doi:10.7150/thno.24997
[Abstract] [Full text] [PDF] [PubMed] [PMC]