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Volume 8 (12); 2018

Research Papers

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The HER2 inhibitor lapatinib potentiates doxorubicin-induced cardiotoxicity through iNOS signaling
Wan-Tseng Hsu, Ching-Ying Huang, Christopher Y.T. Yen, Ann-Lii Cheng, Patrick C.H. Hsieh
Theranostics 2018; 8(12): 3176-3188. doi:10.7150/thno.23207
[Abstract] [Full text] [PDF]


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A hook effect-free immunochromatographic assay (HEF-ICA) for measuring the C-reactive protein concentration in one drop of human serum
Jusung Oh, Hyou-Arm Joung, Hyung Soo Han, Jong Kun Kim, Min-Gon Kim
Theranostics 2018; 8(12): 3189-3197. doi:10.7150/thno.24034
[Abstract] [Full text] [PDF]


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DNA damage predicts prognosis and treatment response in colorectal liver metastases superior to immunogenic cell death and T cells
Johannes Laengle, Judith Stift, Agnes Bilecz, Brigitte Wolf, Andrea Beer, Balazs Hegedus, Stefan Stremitzer, Patrick Starlinger, Dietmar Tamandl, Dietmar Pils, Michael Bergmann
Theranostics 2018; 8(12): 3198-3213. doi:10.7150/thno.24699
[Abstract] [Full text] [PDF]


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Serum amyloid P component therapeutically attenuates atherosclerosis in mice via its effects on macrophages
Dan Xi, Jinzhen Zhao, Kai Guo, Lu Hu, Hui Chen, Weijun Fu, Wenyan Lai, Zhigang Guo
Theranostics 2018; 8(12): 3214-3223. doi:10.7150/thno.22704
[Abstract] [Full text] [PDF]


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Oncogenic TRIM31 confers gemcitabine resistance in pancreatic cancer via activating the NF-κB signaling pathway
Chao Yu, Shiyu Chen, Yuntao Guo, Chengyi Sun
Theranostics 2018; 8(12): 3224-3236. doi:10.7150/thno.23259
[Abstract] [Full text] [PDF]


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Rich club disturbances of the human connectome from subjective cognitive decline to Alzheimer's disease
Tianyi Yan, Wenhui Wang, Liu Yang, Kewei Chen, Rong Chen, Ying Han
Theranostics 2018; 8(12): 3237-3255. doi:10.7150/thno.23772
[Abstract] [Full text] [PDF]


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A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma
Jingya Sun, Xin Wang, Boyun Tang, Hongchun Liu, Minmin Zhang, Yueqin Wang, Fangfang Ping, Jian Ding, Aijun Shen, Meiyu Geng
Theranostics 2018; 8(12): 3256-3267. doi:10.7150/thno.23964
[Abstract] [Full text] [PDF]


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Glypican-3-targeted precision diagnosis of hepatocellular carcinoma on clinical sections with a supramolecular 2D imaging probe
Hai-Hao Han, Yu-Jiao Qiu, Yuan-Yuan Shi, Wen Wen, Xiao-Peng He, Li-Wei Dong, Ye-Xiong Tan, Yi-Tao Long, He Tian, Hong-Yang Wang
Theranostics 2018; 8(12): 3268-3274. doi:10.7150/thno.24711
[Abstract] [Full text] [PDF]


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Colorimetric in situ assay of membrane-bound enzyme based on lipid bilayer inhibition of ion transport
Juan Zhang, Defeng Li, Xiquan Yue, Meiling Zhang, Ping Liu, Genxi Li
Theranostics 2018; 8(12): 3275-3283. doi:10.7150/thno.25123
[Abstract] [Full text] [PDF]


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Response to Single Low-dose 177Lu-DOTA-EB-TATE Treatment in Patients with Advanced Neuroendocrine Neoplasm: A Prospective Pilot Study
Hao Wang, Yuejuan Cheng, Jingjing Zhang, Jie Zang, Hui Li, Qingxing Liu, Jingnan Wang, Orit Jacobson, Fang Li, Zhaohui Zhu, Xiaoyuan Chen
Theranostics 2018; 8(12): 3308-3316. doi:10.7150/thno.25919
[Abstract] [Full text] [PDF]


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Injectable OPF/graphene oxide hydrogels provide mechanical support and enhance cell electrical signaling after implantation into myocardial infarct
Jin Zhou, Xiaoning Yang, Wei Liu, Chunlan Wang, Yuan Shen, Fengzhi Zhang, Huimin Zhu, Hongji Sun, Jiayun Chen, Johnny Lam, Antonios G. Mikos, Changyong Wang
Theranostics 2018; 8(12): 3317-3330. doi:10.7150/thno.25504
[Abstract] [Full text] [PDF]


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Precision-guided long-acting analgesia by hydrogel-immobilized bupivacaine-loaded microsphere
Wenjing Zhang, Cong Ning, Weiguo Xu, Hanze Hu, Mingqiang Li, Guoqing Zhao, Jianxun Ding, Xuesi Chen
Theranostics 2018; 8(12): 3331-3347. doi:10.7150/thno.25276
[Abstract] [Full text] [PDF]


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Functional role of BTB and CNC Homology 1 gene in pancreatic cancer and its association with survival in patients treated with gemcitabine
Xudong Huang, Jian Zheng, Jun Li, Xu Che, Wenle Tan, Wen Tan, Mingming Shao, Xinxin Cheng, Zhongli Du, Yanjie Zhao, Chengfeng Wang, Chen Wu, Dongxin Lin
Theranostics 2018; 8(12): 3366-3379. doi:10.7150/thno.23978
[Abstract] [Full text] [PDF]


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Somatostatin receptor type 2 as a radiotheranostic PET reporter gene for oncologic interventions
Pedram Heidari, Anchisa Kunawudhi, Jordi Martinez-Quintanilla, Alicia Szretter, Khalid Shah, Umar Mahmood
Theranostics 2018; 8(12): 3380-3391. doi:10.7150/thno.24017
[Abstract] [Full text] [PDF]


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Molecular detection of inflammation in cell models using hyperpolarized 13C-pyruvate
Renuka Sriram, Julia Nguyen, Justin DeLos Santos, Linda Nguyen, Jinny Sun, Seth Vigneron, Mark Van Criekinge, John Kurhanewicz, John D. MacKenzie
Theranostics 2018; 8(12): 3400-3407. doi:10.7150/thno.24322
[Abstract] [Full text] [PDF]


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Circular RNA-ZNF609 regulates retinal neurodegeneration by acting as miR-615 sponge
Jia-Jian Wang, Chang Liu, Kun Shan, Bai-Hui Liu, Xiu-Miao Li, Shu-Jie Zhang, Rong-Mei Zhou, Rui Dong, Biao Yan, Xing-Huai Sun
Theranostics 2018; 8(12): 3408-3415. doi:10.7150/thno.25156
[Abstract] [Full text] [PDF]


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Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles
Kasper Bendix Johnsen, Martin Bak, Paul Joseph Kempen, Fredrik Melander, Annette Burkhart, Maj Schneider Thomsen, Morten Schallburg Nielsen, Torben Moos, Thomas Lars Andresen
Theranostics 2018; 8(12): 3416-3436. doi:10.7150/thno.25228
[Abstract] [Full text] [PDF]

Reviews

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Shape-, size- and structure-controlled synthesis and biocompatibility of iron oxide nanoparticles for magnetic theranostics
Wensheng Xie, Zhenhu Guo, Fei Gao, Qin Gao, Dan Wang, Bor-shuang Liaw, Qiang Cai, Xiaodan Sun, Xiumei Wang, Lingyun Zhao
Theranostics 2018; 8(12): 3284-3307. doi:10.7150/thno.25220
[Abstract] [Full text] [PDF]


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Extracellular Vesicles as Markers and Mediators in Sepsis
Pierre Raeven, Johannes Zipperle, Susanne Drechsler
Theranostics 2018; 8(12): 3348-3365. doi:10.7150/thno.23453
[Abstract] [Full text] [PDF]


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Comparison of Burnet's clonal selection theory with tumor cell-clone development
Borros Arneth
Theranostics 2018; 8(12): 3392-3399. doi:10.7150/thno.24083
[Abstract] [Full text] [PDF]