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Volume 6 (10); 2016

Editorial

The Pursuit of Theranostics with CEST MRI
Mark Marty Pagel
Theranostics 2016; 6(10): 1601-1602. doi:10.7150/thno.16337
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper

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Dihydropyrimidine Dehydrogenase Is a Prognostic Marker for Mesenchymal Stem Cell-Mediated Cytosine Deaminase Gene and 5-Fluorocytosine Prodrug Therapy for the Treatment of Recurrent Gliomas
Taemoon Chung, Juri Na, Young-il Kim, Da-Young Chang, Young Il Kim, Hyeonjin Kim, Ho Eun Moon, Keon Wook Kang, Dong Soo Lee, June-Key Chung, Sung-Soo Kim, Haeyoung Suh-Kim, Sun Ha Paek, Hyewon Youn
Theranostics 2016; 6(10): 1477-1490. doi:10.7150/thno.14158
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Novel Cs-Based Upconversion Nanoparticles as Dual-Modal CT and UCL Imaging Agents for Chemo-Photothermal Synergistic Therapy
Yuxin Liu, Luoyuan Li, Quanwei Guo, Lu Wang, Dongdong Liu, Ziwei Wei, Jing Zhou
Theranostics 2016; 6(10): 1491-1505. doi:10.7150/thno.15111
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Simple, Sensitive and Accurate Multiplex Detection of Clinically Important Melanoma DNA Mutations in Circulating Tumour DNA with SERS Nanotags
Eugene J.H. Wee, Yuling Wang, Simon Chang-Hao Tsao, Matt Trau
Theranostics 2016; 6(10): 1506-1513. doi:10.7150/thno.15871
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Cell-Specific Promoters Enable Lipid-Based Nanoparticles to Deliver Genes to Specific Cells of the Retina In Vivo
Yuhong Wang, Ammaji Rajala, Binrui Cao, Michelle Ranjo-Bishop, Martin-Paul Agbaga, Chuanbin Mao, Raju V.S. Rajala
Theranostics 2016; 6(10): 1514-1527. doi:10.7150/thno.15230
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Pharmacokinetic Behaviors of Intravenously Administered siRNA in Glandular Tissues
Yuanyu Huang, Qiang Cheng, Jia-Li Ji, Shuquan Zheng, Lili Du, Lingwei Meng, Yidi Wu, Deyao Zhao, Xiaoxia Wang, Li Lai, Huiqing Cao, Kai Xiao, Shan Gao, Zicai Liang
Theranostics 2016; 6(10): 1528-1541. doi:10.7150/thno.15246
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Ultrasound/Magnetic Targeting with SPIO-DOX-Microbubble Complex for Image-Guided Drug Delivery in Brain Tumors
Ching-Hsiang Fan, Yu-Hang Cheng, Chien-Yu Ting, Yi-Ju Ho, Po-Hung Hsu, Hao-Li Liu, Chih-Kuang Yeh
Theranostics 2016; 6(10): 1542-1556. doi:10.7150/thno.15297
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Assessing Therapeutic Potential of Magnetic Mesoporous Nanoassemblies for Chemo-Resistant Tumors
Lina Pradhan, Bhushan Thakur, Rohit Srivastava, Pritha Ray, Dhirendra Bahadur
Theranostics 2016; 6(10): 1557-1572. doi:10.7150/thno.15231
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Ultrasound-Mediated Microbubble Destruction (UMMD) Facilitates the Delivery of CA19-9 Targeted and Paclitaxel Loaded mPEG-PLGA-PLL Nanoparticles in Pancreatic Cancer
Lingxi Xing, Qiusheng Shi, Kailiang Zheng, Ming Shen, Jing Ma, Fan Li, Yang Liu, Lizhou Lin, Wenzhi Tu, Yourong Duan, Lianfang Du
Theranostics 2016; 6(10): 1573-1587. doi:10.7150/thno.15164
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Label-free CEST MRI Detection of Citicoline-Liposome Drug Delivery in Ischemic Stroke
Huanling Liu, Anna Jablonska, Yuguo Li, Suyi Cao, Dexiang Liu, Hanwei Chen, Peter CM Van Zijl, Jeff W.M. Bulte, Miroslaw Janowski, Piotr Walczak, Guanshu Liu
Theranostics 2016; 6(10): 1588-1600. doi:10.7150/thno.15492
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Holographic Assessment of Lymphoma Tissue (HALT) for Global Oncology Field Applications
Divya Pathania, Hyungsoon Im, Aoife Kilcoyne, Aliyah R. Sohani, Lioubov Fexon, Misha Pivovarov, Jeremy S. Abramson, Thomas C. Randall, Bruce A. Chabner, Ralph Weissleder, Hakho Lee, Cesar M. Castro
Theranostics 2016; 6(10): 1603-1610. doi:10.7150/thno.15534
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Comparison between Three Promising ß-emitting Radionuclides, 67Cu, 47Sc and 161Tb, with Emphasis on Doses Delivered to Minimal Residual Disease
Christophe Champion, Michele A. Quinto, Clément Morgat, Paolo Zanotti-Fregonara, Elif Hindié
Theranostics 2016; 6(10): 1611-1618. doi:10.7150/thno.15132
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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68Ga-HBED-CC-PSMA PET/CT Versus Histopathology In Primary Localized Prostate Cancer: A Voxel-Wise Comparison
Constantinos Zamboglou, Florian Schiller, Tobias Fechter, Gesche Wieser, Cordula Annette Jilg, Alin Chirindel, Nasr Salman, Vanessa Drendel, Martin Werner, Michael Mix, Philipp Tobias Meyer, Anca Ligia Grosu
Theranostics 2016; 6(10): 1619-1628. doi:10.7150/thno.15344
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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High-Resolution PET Imaging with Therapeutic Antibody-based PD-1/PD-L1 Checkpoint Tracers
Michael Hettich, Friederike Braun, Mark D. Bartholomä, Reinhold Schirmbeck, Gabriele Niedermann
Theranostics 2016; 6(10): 1629-1640. doi:10.7150/thno.15253
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Gastrin-releasing Peptide Receptor Imaging in Breast Cancer Using the Receptor Antagonist 68Ga-RM2 And PET
Christian Stoykow, Thalia Erbes, Helmut R Maecke, Stefan Bulla, Mark Bartholomä, Sebastian Mayer, Vanessa Drendel, Peter Bronsert, Martin Werner, Gerald Gitsch, Wolfgang A Weber, Elmar Stickeler, Philipp T Meyer
Theranostics 2016; 6(10): 1641-1650. doi:10.7150/thno.14958
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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RGD Peptide Cell-Surface Display Enhances the Targeting and Therapeutic Efficacy of Attenuated Salmonella-mediated Cancer Therapy
Seung-Hwan Park, Jin Hai Zheng, Vu Hong Nguyen, Sheng-Nan Jiang, Dong-Yeon Kim, Michael Szardenings, Jung Hyun Min, Yeongjin Hong, Hyon E. Choy, Jung-Joon Min
Theranostics 2016; 6(10): 1672-1682. doi:10.7150/thno.16135
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Cancer Theranostic Nanoparticles Self-Assembled from Amphiphilic Small Molecules with Equilibrium Shift-Induced Renal Clearance
Yuan Ma, Quanbing Mou, Mo Sun, Chunyang Yu, Jianqi Li, Xiaohua Huang, Xinyuan Zhu, Deyue Yan, Jian Shen
Theranostics 2016; 6(10): 1703-1716. doi:10.7150/thno.15647
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Investigation of Particle Accumulation, Chemosensitivity and Thermosensitivity for Effective Solid Tumor Therapy Using Thermosensitive Liposomes and Hyperthermia
Wouter J.M. Lokerse, Michiel Bolkestein, Timo L.M. ten Hagen, Marion de Jong, Alexander M.M. Eggermont, Holger Grüll, Gerben A. Koning
Theranostics 2016; 6(10): 1717-1731. doi:10.7150/thno.14960
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Metal-linked Immunosorbent Assay (MeLISA): the Enzyme-Free Alternative to ELISA for Biomarker Detection in Serum
Ru-Jia Yu, Wei Ma, Xiao-Yuan Liu, Hong-Ying Jin, Huan-Xing Han, Hong-Yang Wang, He Tian, Yi-Tao Long
Theranostics 2016; 6(10): 1732-1739. doi:10.7150/thno.16129
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

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Standards and Methodologies for Characterizing Radiobiological Impact of High-Z Nanoparticles
Anna Subiel, Reece Ashmore, Giuseppe Schettino
Theranostics 2016; 6(10): 1651-1671. doi:10.7150/thno.15019
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Optical Aptasensors for Adenosine Triphosphate
Stella Ng, Hui Si Lim, Qian Ma, Zhiqiang Gao
Theranostics 2016; 6(10): 1683-1702. doi:10.7150/thno.15850
[Abstract] [Full text] [PDF] [PubMed] [PMC]