Theranostics 2018; 8(8):2245-2248. doi:10.7150/thno.24181

Editorial

Focused ultrasound with microbubbles induces sterile inflammatory response proportional to the blood brain barrier opening: Attention to experimental conditions

Zsofia I. Kovacs1✉, Scott R. Burks1, Joseph A. Frank1,2✉

1. Frank Laboratory, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD 20892
2. National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892

Abstract

This editorial highlights the findings of McMahon [1] and demonstrates the need for careful attention to experimental conditions that influence microbubble concentration and pharmacokinetics contributed to focused ultrasound-induced blood brain barrier opening and sterile inflammation.

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How to cite this article:
Kovacs ZI, Burks SR, Frank JA. Focused ultrasound with microbubbles induces sterile inflammatory response proportional to the blood brain barrier opening: Attention to experimental conditions. Theranostics 2018; 8(8):2245-2248. doi:10.7150/thno.24181. Available from http://www.thno.org/v08p2245.htm