Theranostics 2017; 7(11):2965-2967. doi:10.7150/thno.21603
New Kid on the Block
Institute of Molecular Medicine and Cell Research, Faculty of Medicine, Albert-Ludwigs-University Freiburg, and German Cancer Consortium (DKTK), Partner site Freiburg, Freiburg, Germany
Cysteine cathepsins are a group of proteases involved in many physiological and pathological processes. Yet, the selective detection and inhibition of individual cathepsins is still challenging. This editorial is discussing the context of a recent work introducing a designed ankyrin repeat protein (DARPin) as novel approach for selective targeting of the protease cathepsin B.
Keywords: Cathepsin B, DARPin, protease inhibition, protease imaging
Reinheckel T. New Kid on the Block. Theranostics 2017; 7(11):2965-2967. doi:10.7150/thno.21603. Available from http://www.thno.org/v07p2965.htm