Theranostics 2016; 6(9):1362-1377. doi:10.7150/thno.15335

Review

Targeted Nanotheranostics for Future Personalized Medicine: Recent Progress in Cancer Therapy

Sung Duk Jo1*, Sook Hee Ku1*, You-Yeon Won1,2, Sun Hwa Kim1✉, Ick Chan Kwon1,3✉

1. Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.
2. School of Chemical Engineering, and Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA.
3. KU-KIST School, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul02841, Republic of Korea.
*These authors contributed equally to this work.

Abstract

Recently, many theranostic nanomaterials have been developed by integrating therapeutic and diagnostic agents in a single regimen. Real-time visualization of nano drug carrier biodistributions, drug release processes and therapeutic responses can provide critical information needed for dynamically optimizing treatment operations in a personalized manner in real time. This review highlights recent progresses in the development of multifunctional nanoparticles possessing both therapeutic and imaging functionalities for cancer therapy. The advantages of using nanoparticle platforms are discussed. Examples demonstrating various combinations of imaging and therapeutic modalities are highlighted.

Keywords: Nanotheranostics, Personalized medicine, Cancer therapy.

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How to cite this article:
Jo SD, Ku SH, Won YY, Kim SH, Kwon IC. Targeted Nanotheranostics for Future Personalized Medicine: Recent Progress in Cancer Therapy. Theranostics 2016; 6(9):1362-1377. doi:10.7150/thno.15335. Available from http://www.thno.org/v06p1362.htm