Full Text | PDF

Share on tweeters Share on facebook Share on linkedin Share on googleplus

Theranostics 2012; 2(3):238-250. doi:10.7150/thno.3509 This issue Cite

Review

Applications of Functionalized Fullerenes in Tumor Theranostics

Zhiyun Chen, Lijing Ma, Ying Liu✉, Chunying Chen

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China.

✉ Corresponding author: Dr. Ying Liu, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), No.11, 1st North Street, Zhongguancun, Beijing 100190, China. Tel: +86-10-82545526 More

Citation:
Chen Z, Ma L, Liu Y, Chen C. Applications of Functionalized Fullerenes in Tumor Theranostics. Theranostics 2012; 2(3):238-250. doi:10.7150/thno.3509. https://www.thno.org/v02p0238.htm
Other styles

File import instruction

Abstract

Functionalized fullerenes with specific physicochemical properties have been developed for cancer diagnosis and therapy. Notably, metallofullerene is a new class of magnetic resonance imaging (MRI) contrast-enhancing agent, and may have promising applications for clinical diagnosis. Polyhydroxylated and carboxyl fullerenes have been applied to photoacoustic imaging. Moreover, in recent years, functionalized fullerenes have shown potential in tumor therapies, such as photodynamic therapy, photothermal treatment, radiotherapy and chemotherapeutics. Their antitumor effects may be associated with the modulation of oxidative stress, anti-angiogenesis, and immunostimulatory activity. While various types of novel nanoparticle agents have been exploited in tumor theranostics, their distribution, metabolism and toxicity in organisms have also been a source of concern among researchers. The present review summarizes the potential of fullerenes as tumor theranostics agents and their possible underlying mechanisms are discussed.

Keywords: Functionalized fullerenes, nanoparticles, cancer diagnosis, cancer therapy, theranostics.

Citation styles

APA
Chen, Z., Ma, L., Liu, Y., Chen, C. (2012). Applications of Functionalized Fullerenes in Tumor Theranostics. Theranostics, 2(3), 238-250. https://doi.org/10.7150/thno.3509.

ACS
Chen, Z.; Ma, L.; Liu, Y.; Chen, C. Applications of Functionalized Fullerenes in Tumor Theranostics. Theranostics 2012, 2 (3), 238-250. DOI: 10.7150/thno.3509.

NLM
Chen Z, Ma L, Liu Y, Chen C. Applications of Functionalized Fullerenes in Tumor Theranostics. Theranostics 2012; 2(3):238-250. doi:10.7150/thno.3509. https://www.thno.org/v02p0238.htm

CSE
Chen Z, Ma L, Liu Y, Chen C. 2012. Applications of Functionalized Fullerenes in Tumor Theranostics. Theranostics. 2(3):238-250.

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
Popup Image

©2024 Ivyspring International Publisher. Terms of use