Brain Theranostics: What have we accomplished and the most promising future directions
Prof. Rachela Popovtzer
Faculty of Engineering & The Institute of Nanotechnology and Advanced Materials
Brain theranostics is an exciting and growing field. Integrating diagnosis and therapy holds immense promise for the treatment of brain disease, answering various challenges that exist particularly within difficult-to-access - if not completely inaccessible - deep brain structures. Recent developments have promoted effective, non-invasive diagnosis and therapy of various brain diseases. Progress in the field holds great promise for treatment of brain cancer, psychiatric diseases, motor or memory impairments, Stroke, Autism and other brain disorders. However, significant challenges remain, such as overcoming the limitations of blood–brain barrier permeability, targeted delivery to specific brain regions, controlled delivery, and early diagnosis.
The emerging field of brain theranostics involves concepts associated with the design of probes to image and monitor brain disease, monitor levels of biomarkers in tissue, and engineering probes for improved diagnosis and treatment efficacy.
The goal of this themed issue on Brain Theranostics is to invite leading experts in the fields of neurobiology, psychiatry, diagnostics, imaging and nanotechnology to discuss their most recent discoveries in associated topics, and to share their vision on the future development of this emerging field. Unsolicited submissions are also welcome.
Topics include, but are not limited to:
- Nanoparticle platforms for targeted imaging and therapy of brain disease
- Techniques for effective blood-brain barrier penetration
- Specific and sensitive diagnostic probes/ imaging modalities for early detection
- Platforms and methods for controlled drug delivery to the brain
- Theranostic biomarkers
Both reviews and research articles will be considered. All invited and contributed manuscripts will undergo the standard peer-review procedure of the Journal “Theranostics”, and be scrutinized by the guest editors and at least two additional expert reviewers in the field. The manuscript submission DEADLINE is set for May 30, 2017 and the first decision will be made within 4 weeks from submission, after the peer-review process.
Manuscripts for the special issue can be directly submitted online at http://www.thno.org/ms/submit?subgroup=brainthno (mark "Brain Theranostics Special Issue" in the "Suggested reviewers" field to identify the paper).
Detailed formatting instructions, in particular, the formatting of references, can be found in http://www.thno.org/ms/author.
All inquiries should be sent to the guest editor(s) at the above email address.