Review GRP78 in human diseases: From molecular chaperone to therapeutic target Full text PDF
Research Paper c-Met-targeted NIR-II imaging for precision management of oral squamous cell carcinoma and premalignant lesions Full text PDF
Research Paper Intermittent hypoxia ameliorates behavioral deficits and exerts neurorestoration in a mouse photothrombotic stroke model Full text PDF
Research Paper A clinically translatable, irreversibly attenuated Salmonella strain as a next-generation adjuvant for checkpoint immunotherapy Full text PDF
Research Paper DKK3–CKAP4 signaling drives fibroimmune remodeling and hair follicle miniaturization in androgenetic alopecia Full text PDF
Research Paper Porphyrin-lipid nanotheranostics for multimodal imaging of nodal disease in preclinical oral cancers Full text PDF
Issue 10; 2026
Founding Editor-in-Chief:
Prof. Xiaoyuan (Shawn) Chen, PhD
Profile
Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.
Background: Ischemic stroke disproportionately impacts the elderly with a higher risk and poor repair. Current therapeutic options are constrained by narrow time windows, strict contraindications, and suboptimal efficacy in older patients, leaving a critical unmet clinical need. Hypoxia-based interventions exert preclinical neuroprotective effects, yet the effects and underlying mechanisms of intermittent hypoxia (IH) in elderly patients with ischemic ...