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Volume 6 (5); 2016

Research Paper

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Nano-zymography Using Laser-Scanning Confocal Microscopy Unmasks Proteolytic Activity of Cell-Derived Microparticles
Aurélien Briens, Maxime Gauberti, Jérôme Parcq, Joan Montaner, Denis Vivien, Sara Martinez de lizarrondo
Theranostics 2016; 6(5): 610-626. doi:10.7150/thno.13757
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Enhanced Anti-Tumor Efficacy through a Combination of Integrin αvβ6-Targeted Photodynamic Therapy and Immune Checkpoint Inhibition
Liquan Gao, Chenran Zhang, Duo Gao, Hao Liu, Xinhe Yu, Jianhao Lai, Fan Wang, Jian Lin, Zhaofei Liu
Theranostics 2016; 6(5): 627-637. doi:10.7150/thno.14792
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Spectrum and Classification of ATP7B Variants in a Large Cohort of Chinese Patients with Wilson's Disease Guides Genetic Diagnosis
Yi Dong, Wang Ni, Wan-Jin Chen, Bo Wan, Gui-Xian Zhao, Zhu-Qing Shi, Yue Zhang, Ning Wang, Long Yu, Jian-Feng Xu, Zhi-Ying Wu
Theranostics 2016; 6(5): 638-649. doi:10.7150/thno.14596
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Multimodal Somatostatin Receptor Theranostics Using [64Cu]Cu-/[177Lu]Lu-DOTA-(Tyr3)octreotate and AN-238 in a Mouse Pheochromocytoma Model
Martin Ullrich, Ralf Bergmann, Mirko Peitzsch, Erik F. Zenker, Marc Cartellieri, Michael Bachmann, Monika Ehrhart-Bornstein, Norman L. Block, Andrew V. Schally, Graeme Eisenhofer, Stefan R. Bornstein, Jens Pietzsch, Christian G. Ziegler
Theranostics 2016; 6(5): 650-665. doi:10.7150/thno.14479
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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A Comparison Study of iTEP Nanoparticle-Based CTL Vaccine Carriers Revealed a Surprise Relationship between the Stability and Efficiency of the Carriers
Shuyun Dong, Tiefeng Xu, Peng Zhao, Kristin N. Parent, Mingnan Chen
Theranostics 2016; 6(5): 666-678. doi:10.7150/thno.14068
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Cisplatin Prodrug-Conjugated Gold Nanocluster for Fluorescence Imaging and Targeted Therapy of the Breast Cancer
Fangyuan Zhou, Bing Feng, Haijun Yu, Dangge Wang, Tingting Wang, Jianping Liu, Qingshuo Meng, Siling Wang, Pengcheng Zhang, Zhiwen Zhang, Yaping Li
Theranostics 2016; 6(5): 679-687. doi:10.7150/thno.14556
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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A Phosphorus Phthalocyanine Formulation with Intense Absorbance at 1000 nm for Deep Optical Imaging
Yang Zhou, Depeng Wang, Yumiao Zhang, Upendra Chitgupi, Jumin Geng, Yuehang Wang, Yuzhen Zhang, Timothy R. Cook, Jun Xia, Jonathan F. Lovell
Theranostics 2016; 6(5): 688-697. doi:10.7150/thno.14555
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Preliminary Therapy Evaluation of 225Ac-DOTA-c(RGDyK) Demonstrates that Cerenkov Radiation Derived from 225Ac Daughter Decay Can Be Detected by Optical Imaging for In Vivo Tumor Visualization
Darpan N. Pandya, Roy Hantgan, Mikalai M. Budzevich, Nancy D. Kock, David L. Morse, Izadora Batista, Akiva Mintz, King C. Li, Thaddeus J. Wadas
Theranostics 2016; 6(5): 698-709. doi:10.7150/thno.14338
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Thrombus-Targeted Theranostic Microbubbles: A New Technology towards Concurrent Rapid Ultrasound Diagnosis and Bleeding-free Fibrinolytic Treatment of Thrombosis
Xiaowei Wang, Yannik Gkanatsas, Jathushan Palasubramaniam, Jan David Hohmann, Yung Chih Chen, Bock Lim, Christoph E Hagemeyer, Karlheinz Peter
Theranostics 2016; 6(5): 726-738. doi:10.7150/thno.14514
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Designing 3D Mesenchymal Stem Cell Sheets Merging Magnetic and Fluorescent Features: When Cell Sheet Technology Meets Image-Guided Cell Therapy
Gabriel Rahmi, Laetitia Pidial, Amanda K. A. Silva, Eléonore Blondiaux, Bertrand Meresse, Florence Gazeau, Gwennhael Autret, Daniel Balvay, Charles André Cuenod, Silvana Perretta, Bertrand Tavitian, Claire Wilhelm, Christophe Cellier, Olivier Clément
Theranostics 2016; 6(5): 739-751. doi:10.7150/thno.14064
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Folate-modified Chitosan Nanoparticles Containing the IP-10 Gene Enhance Melanoma-specific Cytotoxic CD8+CD28+ T Lymphocyte Responses
Jian He, Siliang Duan, Xia Yu, Zhiyong Qian, Sufang Zhou, Zhiyong Zhang, Xianing Huang, Yong Huang, Jing Su, Chunhui Lai, Jinyu Meng, Nuo Zhou, Xiaoling Lu, Yongxiang Zhao
Theranostics 2016; 6(5): 752-761. doi:10.7150/thno.14527
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

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DNA Nanotechnology for Cancer Therapeutics
Vinit Kumar, Stefano Palazzolo, Samer Bayda, Giuseppe Corona, Giuseppe Toffoli, Flavio Rizzolio
Theranostics 2016; 6(5): 710-725. doi:10.7150/thno.14203
[Abstract] [Full text] [PDF] [PubMed] [PMC]