Theranostics 2013; 3(4):275-281. doi:10.7150/thno.4983

Research Paper

Facile Synthesis and Potential Bioimaging Applications of Hybrid Upconverting and Plasmonic NaGdF4: Yb3+, Er3+/Silica/Gold Nanoparticles

Sha Liu1,2, Guanying Chen1, Tymish Y. Ohulchanskyy1, Mark T. Swihart1,2✉, Paras N. Prasad1✉

1. Institute for Lasers, Photonics and Biophotonics, University at Buffalo, The State University of New York, Buffalo, New York 14260, United States;
2. Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, New York 14260, United States.

Abstract

We present a simple method for preparing water dispersible NaGdF4: Yb3+, Er3+/silica/gold nanoparticles. The emission intensity and color of the upconverting cores are modulated by the plasmonic absorbance and field enhancement from the gold nanoparticles. The applicability of hybrid NPs for multi-modal bioimaging probes is illustrated by in vitro confocal microscopy of living cancer cells.

Keywords: Upconversion, Gold, Nanoparticles, Photoluminescence, Bioimaging.

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How to cite this article:
Liu S, Chen G, Ohulchanskyy TY, Swihart MT, Prasad PN. Facile Synthesis and Potential Bioimaging Applications of Hybrid Upconverting and Plasmonic NaGdF4: Yb3+, Er3+/Silica/Gold Nanoparticles. Theranostics 2013; 3(4):275-281. doi:10.7150/thno.4983. Available from http://www.thno.org/v03p0275.htm