Theranostics 2012; 2(4):333-334. doi:10.7150/thno.4376

Editorial

Reporter Gene Imaging in Therapy and Diagnosis

Pritha Ray, Abhijit De

ACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai, India

Abstract

Noninvasive molecular imaging using reporter genes is a relatively recent field in biomedical imaging that holds great promises for disease diagnosis and therapy. As modern medicine is moving towards personalized medicine, targeted biomolecule based therapies is gaining popularity that requires careful and systematic validation. Reporter genes have emerged as important generalizable tools to overcome the shortcomings of direct evaluation of individual biomolecules and are being applied in various fields such as cell therapy, stem cell therapy, immune therapy, viral gene delivery through optical, radionuclide, magnetic resonance imaging techniques. New approaches to image protein-protein interaction, protein phosphorylation, protein folding that are crucial parameters for theranostic study using reporter genes are being developed. All these new technologies and relevant preclinical and clinical researches will determine the success of early detection and personalized therapy in the future.

Keywords: reporter genes, molecular imaging

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
How to cite this article:
Ray P, De A. Reporter Gene Imaging in Therapy and Diagnosis. Theranostics 2012; 2(4):333-334. doi:10.7150/thno.4376. Available from http://www.thno.org/v02p0333.htm