Online advance articles

LncRNA AY promotes hepatocellular carcinoma metastasis by stimulating ITGAV transcription
Chun Lan Kang, Bing Qi, Qian Qian Cai, Li Sheng Fu, Ying Yang, Chang Tang, Ping Zhu, Jing Pan, Mei Hua Chen, Xing Zhong Wu
Theranostics online date 2019-5-22; doi:10.7150/thno.32854; accepted
[Author manuscript]

A compound AC1Q3QWB selectively disrupts HOTAIR-mediated recruitment of PRC2 and enhances cancer therapy of DZNep
Yansheng Li, Yu Ren, Yunfei Wang, Yanli Tan, Qixue Wang, Jinquan Cai, Junhu Zhou, Chao Yang, Kai Zhao, Kaikai Yi, Weili Jin, Lin Wang, Mingyang Liu, Jingxuan Yang, Min Li, Chunsheng Kang
Theranostics online date 2019-5-22; doi:10.7150/thno.35188; accepted
[Author manuscript]

Vitamin C kills thyroid cancer cells through ROS-dependent inhibition of MAPK/ERK and PI3K/AKT pathways via distinct mechanisms
Xi Su, Zhen Shen, Qi Yang, Fang Sui, Jun Pu, Jingjing Ma, Sharui Ma, Demao Yao, Meiju Ji and Peng Hou
Theranostics online date 2019-5-22; doi:10.7150/thno.35219; accepted
[Author manuscript]

Human mesenchymal stem cell-treated regulatory CD23+CD43+ B cells alleviate intestinal inflammation
Xiaoyong Chen, Chuang Cai, Dijing Xu, Qiuli Liu, Shuwei Zheng, Longshan Liu, Gang Li, Xiaoran Zhang, Xiaoping Li, Yuanchen Ma, Li Huang, Jieying Chen, Jiahao Shi, Xin Du, Wenjie Xia, Andy Peng Xiang, Yanwen Peng
Theranostics online date 2019-5-22; doi:10.7150/thno.32260; accepted
[Author manuscript]

Au Hollow Nanorods-Chimeric Peptide nanocarrier for NIR-Ⅱ Photothermal therapy and Real-time Apoptosis Imaging for Tumor Theranostic
Weiyun Zhang, Kai Cai, Xuyu Li, Jin Zhang, Zhaoyu Ma, Mohamed F. Foda, Yongli Mu, Xinxin Dai and Heyou Han
Theranostics online date 2019-5-22; doi:10.7150/thno.35560; accepted
[Author manuscript]

Controllable Autocatalytic Cleavage-Mediated Fluorescence Recovery for Homogeneous Sensing of Alkyladenine DNA Glycosylase from Human Cancer Cells
Li-juan Wang, †, Ming-li Luo, †, Xiao-yun Yang, †, Xiao-fang Li, †, Yanxia Wu, Chun-yang Zhang
Theranostics online date 2019-5-22; doi:10.7150/thno.35393; accepted
[Author manuscript]

Methylation of RCAN1.4 mediated by DNMT1 and DNMT3b enhances hepatic stellate cells activation and liver fibrogenesis through Calcineurin/NFAT3 signaling
Xue-yin Pan, Hong-mei You, Ling Wang, Yi-hui Bi, Yang Yang, Hong-wu Meng, Xiao-ming Meng, Tao-tao Ma, Cheng Huang, Jun Li
Theranostics online date 2019-5-22; doi:10.7150/thno.32710; accepted
[Author manuscript]

Development of a Biocompatible Copolymer Nanocomplex to Deliver VEGF siRNA for Triple Negative Breast Cancer
Zhen Zhao, Yuanke Li, Shukla Ravi, Hao Liu, Akshay Jain, Ashutosh Barve, Kun Cheng
Theranostics online date 2019-5-22; doi:10.7150/thno.34314; accepted
[Author manuscript]

Employing macrophage-derived microvesicle for kidney-targeted delivery of dexamethasone: An efficient therapeutic strategy against renal inflammation and fibrosis
Tao-Tao Tang, Lin-Li Lv, Bin Wang, Jing-Yuan Cao, Ye Feng, Zuo-Lin Li, Min Wu, Feng-Mei Wang, Yi Wen, Le-Ting Zhou, Hai-Feng Ni, Ping-Sheng Chen, Ning Gu, Steven D. Crowley, Bi-Cheng Liu
Theranostics online date 2019-5-22; doi:10.7150/thno.33520; accepted
[Author manuscript]

18F-FDG PET/CT radiomic analysis with machine learning for identifying bone marrow involvement in the patients with suspected relapsed acute leukemia
Hebei Li, Chongrui Xu, Bowen Xin, Chaojie Zheng, Yunyun Zhao, Keji Hao, Qian Wang, Richard L. Wahl, Xiuying Wang, Yun Zhou
Theranostics online date 2019-5-22; doi:10.7150/thno.33841; accepted
[Author manuscript]

Embryonic stem cells modulate the cancer-permissive microenvironment of human uveal melanoma
Jiahui Liu, Zheqian Huang, Liu Yang, Xiaoran Wang, Shoubi Wang, Chaoyang Li, Ying Liu, Yaqi Cheng, Bowen Wang, Xuan Sang, Xiongjun He, Chenjie Wang, Tengfei Liu, ChengXiu Liu, Lin Jin, Chang Liu, Linghua Wang, & Zhichong Wang
Theranostics online date 2019-5-22; doi:10.7150/thno.33139; accepted
[Author manuscript]

Total internal reflection-based single-vesicle in situ quantitative and stoichiometric analysis of tumor-derived exosomal microRNAs for diagnosis and treatment monitoring
Dinggeng He, Huizhen Wang, See-Lok Ho, Hei-Nga Chan, Luo Hai, Xiaoxiao He, Kemin Wang, Hung-Wing Li
Theranostics online date 2019-5-22; doi:10.7150/thno.33683; accepted
[Author manuscript]

Focused ultrasound-augmented targeting delivery of nanosonosensitizers from homogenous exosomes for enhanced sonodynamic cancer therapy
Yichen Liu†, Lianmei Bai†, Kaili Guo, Yali Jia, Kun Zhang, Quanhong Liu, Pan Wang, Xiaobing Wang
Theranostics online date 2019-5-22; doi:10.7150/thno.33183; accepted
[Author manuscript]

Sex modulates the ApoE ε4 effect on brain tau deposition measured by 18F-AV-1451 PET in individuals with mild cognitive impairment
Min Liu, Manish D Paranjpe, Xin Zhou, Phan Q. Duy, Manu S Goyal, Tammie L.S. Benzinger, Jie Lu, Rongfu Wang, Yun Zhou, for the Alzheimer’s Disease Neuroimaging Initiative
Theranostics online date 2019-5-22; doi:10.7150/thno.35366; accepted
[Author manuscript]

Novel Ginsenoside Based Multifunctional Liposomal Delivery System for Combination Therapy of Gastric Cancer
Chao Hong, Dan Wang, Jianming Liang, Yizhen Guo, Ying Zhu, Jiaxuan Xia, Jing Qin, Huaxing Zhan, Jianxin Wang
Theranostics online date 2019-5-22; doi:10.7150/thno.34953; accepted
[Author manuscript]

Facile fluorescence monitoring of gut microbial metabolite trimethylamine N-oxide via molecular recognition of guanidinium-modified calixarene
Huijuan Yu, Wen-Chao Geng, Zhe Zheng, Jie Gao, Dong-Sheng Guo, and Yuefei Wang
Theranostics online date 2019-5-22; doi:10.7150/thno.33459; accepted
[Author manuscript]

RIP3 promotes colitis-associated colorectal cancer by controlling tumor cell proliferation and CXCL1-induced immune suppression
Zhen-Yu Liu, Ming-Zheng, Yi-Ming Li, Xin-Yu Fan, Jian-Chao Wang, Zhu-Chun Li, Hai-Jiao Yang, Jing-Min Yu, Jian Cui, Jian-Li Jiang, Juan Tang & Zhi-Nan Chen
Theranostics online date 2019-5-22; doi:10.7150/thno.32126; accepted
[Author manuscript]

Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities
Yuhao Liu, Chao Wang, Gang Wang, Youqiang Sun, Zhangrong Deng, Leilei Chen, Kai Chen, Jennifer Tickner, Jacob Kenny, Dezhi Song, Qingwen Zhang, Haibin Wang, Zhenqiu Chen, Chi Zhou, Wei He, Jiake Xu
Theranostics online date 2019-5-11; doi:10.7150/thno.35414; accepted
[Author manuscript]

LncRNA-MTA2TR functions as a promoter in pancreatic cancer via driving deacetylation-dependent accumulation of HIF-1α
Gang Zhao, Zhu Zeng, Feng-yu Xu, Hai Zheng, Cheng Ping, Qing-yong Chen, Zeng Ye, Jian-xin Zhong, Shi-jiang Deng, Ming-liang Liu, Kang Huang, Qiang Li, Wei Li, Yu-hang Hu, Fan Wang, Chun-you Wang
Theranostics online date 2019-5-11; doi:10.7150/thno.34559; accepted
[Author manuscript]

Focused ultrasound activation of voltage-gated calcium channels requires depolarizing TRPC1 sodium currents
Scott R. Burks, Rebecca M. Lorsung, Matthew E. Nagle, Tsang-Wei Tu, Joseph A. Frank
Theranostics online date 2019-5-11; doi:10.7150/thno.33876; accepted
[Author manuscript]

PMMA-Fe3O4 for internal mechanical support and magnetic thermal ablation of bone tumors
Kexiao Yu, Bing Liang, Yuanyi Zheng, Agata Exner, Michael Kolios, Tiantian Xu, Dajing Guo, Xiaojun Cai, Zhigang Wang, Haitao Ran, Lei Chu, and Zhongliang Deng
Theranostics online date 2019-5-11; doi:10.7150/thno.34157; in press
[Author manuscript]

Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma/paraganglioma
Bruna Calsina, Luis Jaime Castro-Vega, Rafael Torres-Pérez, Lucía Inglada-Pérez, Maria Currás-Freixes, Juan María Roldán-Romero, Veronika Mancikova, Rocío Letón, Laura Remacha, María Santos, Nelly Burnichon, Charlotte Lussey-Lepoutre, Elena Rapizzi, Osvaldo Graña, Cristina Álvarez-Escolá, Aguirre A de Cubas, Javier Lanillos, Alfonso Cordero-Barreal, Ángel M Martínez-Montes, Alexandre Bellucci, Lau
Theranostics online date 2019-5-11; doi:10.7150/thno.35458; accepted
[Author manuscript]

Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner
Jiatao Li, Kevin Y. Yang, Rachel Chun Yee Tam, Vicken W. Chan, Hui Yao Lan, Shohei Hori, Bin Zhou, Kathy O. Lui
Theranostics online date 2019-5-11; doi:10.7150/thno.32734; accepted
[Author manuscript]

MRP4 sustains Wnt/β-catenin signaling for pregnancy, endometriosis and endometrial cancer
Jun-Jiang Chen, Zhi-Jie Xiao, Xiaojing Meng, Yan Wang, Mei Kuen Yu, Wen Qing Huang, Xiao Sun, Hao Chen, Yong-Gang Duan, Maria Pik Wong, Hsiao Chang Chan, Fei Zou, Ye Chun Ruan
Theranostics online date 2019-5-11; doi:10.7150/thno.32097; accepted
[Author manuscript]

Point-of-care Ratiometric Fluorescence Imaging of Tissue for the Diagnosis of Ovarian Cancer
Xiaobo Zhou, Yawei Liu, Qiyu Liu, Luzhe Yan, Meng Xue, Wei Yuan, Mei Shi, Wei Feng, Congjian Xu and Fuyou Li
Theranostics online date 2019-5-11; doi:10.7150/thno.35322; in press
[Author manuscript]

pH- and photothermal-driven multistage delivery nanoplatform for overcoming cancer drug resistance
Wenjing Huang, Hao Zhao, Jiangshan Wan, Yang Zhou, Qingbo Xu, Yanbing Zhao, Xiangliang Yang, Lu Gan
Theranostics online date 2019-5-11; doi:10.7150/thno.33958; in press
[Author manuscript]

Site-specifically labeled 89Zr-DFO-trastuzumab improves immuno-reactivity and tumor uptake for immuno-PET in a subcutaneous HER2-positive xenograft mouse model
Lotte K. Kristensen, Camilla Christensen, Mette M. Jensen, Brian J. Agnew, Christina Schjöth-Frydendahl, Andreas Kjaer, Carsten H. Nielsen
Theranostics online date 2019-5-11; doi:10.7150/thno.32883; in press
[Author manuscript]

Ubiquitin specific peptidase 5 regulates colorectal cancer cell growth by stabilizing Tu translation elongation factor
Xin Xu, Aiwen Huang, Ximao Cui, Kunkun Han, Xiaodan Hou, Qun Wang, Long Cui, Yili Yang
Theranostics online date 2019-5-11; doi:10.7150/thno.33803; in press
[Author manuscript]

Combination Therapy of TGF-β Blockade and Commensal-derived Probiotics Provides Enhanced Antitumor Immune Response and Tumor Suppression
Linlin Shi, Jianyong Sheng, Mengli Wang, Han Luo, Jun Zhu, Bixiang Zhang, Zhi Liu, Xiangliang Yang
Theranostics online date 2019-5-11; doi:10.7150/thno.35131; in press
[Author manuscript]

Ascorbic Acid Induced HepG2 Cells’ Apoptosis via Intracellular Reductive Stress
Xiaonan Gao, Keyan Wei, Bo Hu, Kehua Xu, Bo Tang
Theranostics 2019; doi:10.7150/thno.33783; in press
[Author manuscript]

Endocytosis-mediated mitochondrial transplantation: Transferring normal human astrocytic mitochondria into glioma cells rescues aerobic respiration and enhances radiosensitivity
Chao Sun, Xiongxiong Liu, Bing Wang, Zhenhua Wang, Yang Liu, Cuixia Di, Jing Si, Hongyan Li, Qingfeng Wu, Dan Xu, Ji Li, Gang Li, Yupei Wang, Fang Wang and Hong Zhang
Theranostics online date 2019-5-8; doi:10.7150/thno.33100; in press
[Author manuscript]

A versatile supramolecular nanoadjuvant that activates NF-κB for cancer immunotherapy
Yan Xu, Youzhi Wang, Quanli Yang, Zhijia Liu, Zhiqiang Xiao, Zhicheng Le, Zhimou Yang, and Chengbiao Yang
Theranostics online date 2019-5-11; doi:10.7150/thno.34031; in press
[Author manuscript]

Lack of spleen signal on diffusion weighted MRI is associated with high tumor burden and poor prognosis in Multiple Myeloma: a link to extramedullary hematopoiesis?
Leo Rasche, Manoj Kumar, Grant Gershner, Rohan Samant, Rudy Van Hemert, Anke Heidemeier, Constantin Lapa, Thorsten Bley, Andreas Buck, James McDonald, Jens Hillengass, Joshua Epstein, Sharmilan Thanendrarajan, Carolina Schinke, Frits van Rhee, Maurizio Zangari, Bart Barlogie, Faith E Davies, Gareth J Morgan, Niels Weinhold
Theranostics online date 2019-5-8; doi:10.7150/thno.33289; accepted
[Author manuscript]

IL-21-based therapies induce clearance of hepatitis B virus persistence in mouse models
Zhongliang Shen, Jing Liu, Jingwen Wu, Yuanfei Zhu, Gaiyun Li, Jun Wang, Mengjun Luo, Qiang Deng, Jiming Zhang, and Youhua Xie
Theranostics online date 2019-5-8; doi:10.7150/thno.35331; in press
[Author manuscript]

Suppression of YAP/TAZ-Notch1-NICD axis by bromodomain and extraterminal protein inhibition impairs liver regeneration
Chen Liu, Xiawei Cheng, Juntao Chen, Yao Wang, Xiaoying Wu, Rui Tian, Baoqing Liu, Xianfeng Ding, Qiming Sun, Weihua Gong
Theranostics online date 2019-5-8; doi:10.7150/thno.33370; in press
[Author manuscript]

Circulating miR-338 Cluster activities on osteoblast differentiation: Potential Diagnostic and Therapeutic Targets for Postmenopausal Osteoporosis
Chujiao Lin, Shuaitong Yu, Runze Jin, Yao Xiao, Minghui Pan, Fei Pei, Xiaojing Zhu, Huarong Huang, Zunyi Zhang, Shuo Chen, Huan Liu, Zhi Chen
Theranostics online date 2019-5-8; doi:10.7150/thno.34493; in press
[Author manuscript]

MicroRNA Biogenesis is Enhanced by Liposome-encapsulated Pin1 Inhibitor in Hepatocellular Carcinoma
Dan Sun, Shuangyan Tan, Yanli Xiong, Wenchen Pu, Jiao Li, Wei Wei, Canhua Huang, Yu-Quan Wei, Yong Peng
Theranostics online date 2019-5-8; doi:10.7150/thno.34588; accepted
[Author manuscript]

Decoding cancer heterogeneity: studying patient-specific signaling signatures towards personalized cancer therapy
Efrat Flashner-Abramson, Swetha Vasudevan, Ibukun Adesoji Adejumobi, Amir Sonnenblick, Nataly Kravchenko-Balasha
Theranostics online date 2019-5-8; doi:10.7150/thno.31657; accepted
[Author manuscript]

Dual-Channel Fluorescence Imaging of Hydrogel Degradation and Tissue Regeneration in the Brain
G. Kate Park, Su-Hwan Kim, Kyungmin Kim, Priyanka Das, Byung-Gee Kim, Satoshi Kashiwagi, Hak Soo Choi, and Nathaniel S. Hwang
Theranostics online date 2019-5-8; doi:10.7150/thno.35606; in press
[Author manuscript]

Lymphocytic subsets play distinct roles in heart diseases
Jing Wang, Yi Duan, Joost PG Sluijter, Junjie Xiao
Theranostics online date 2019-5-8; doi:10.7150/thno.33112; in press
[Author manuscript]

Liquid biopsy in ovarian cancer: recent advances in circulating extracellular vesicle detection for personalized medicine
Lei Chang, Jie Ni, Ying Zhu, Bairen Pang, Peter Graham, Hao Zhang, Yong Li
Theranostics online date 2019-5-7; doi:10.7150/thno.34692; in press
[Author manuscript]

Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells
Verena Trümper, Andreas von Knethen, Annegret Preuß, Eugeny Ermilov, Steffen Hackbarth, Laura Kuchler, Sandra Gunne, Anne Schäfer, Tobias Bornhütter, Bernhard Brüne, Beate Röder, Michael Schindler, Michael J. Parnham and Tilo Knape
Theranostics online date 2019-5-8; doi:10.7150/thno.29367; accepted
[Author manuscript]

LncRNA DCRF regulates cardiomyocyte autophagy by targeting miR-551b-5p in diabetic cardiomyopathy
Yu Feng, Weiting Xu, Wei Zhang, Wenjing Wang, Tong Liu, Xiang Zhou
Theranostics online date 2019-5-8; doi:10.7150/thno.31052; in press
[Author manuscript]

ZnAs@SiO2 nanoparticles as a potential anti-tumor drug for targeting stemness and epithelial-mesenchymal transition in hepatocellular carcinoma
Yongquan Huang, Bin Zhou, Hui Luo, Junjie Mao, Yin Huang, Ke Zhang, Chaoming Mei, Yan Yan, Hongjun Jin, Jinhao Gao, Zhongzhen Su, Pengfei Pang, Dan Li, Hong Shan
Theranostics online date 2019-5-22; doi:10.7150/thno.32462; accepted
[Author manuscript]

Repeated ultrasound treatment of tau transgenic mice clears neuronal tau by autophagy and improves behavioral functions
Rucha Pandit, Gerhard Leinenga and Jürgen Götz
Theranostics online date 2019-4-30; doi:10.7150/thno.34388; in press
[Author manuscript]

GSH Activated Biotin-tagged Near-Infrared Probe for Efficient Cancer Imaging
Ruiying Guo, Feng Huang, Bo Zhang, Youyou Yan, Jinxin Che, Yizhen Jin, Yuxin Zhuang, Rong Dong, Yangling Li, Biqin Tan, Rui Song, Yongzhou Hu, Xiaowu Dong, Xin Li, Nengming Lin
Theranostics online date 2019-4-30; doi:10.7150/thno.32742; in press
[Author manuscript]

Alarmin augments the antitumor immunity of lentiviral vaccine in autochthonous hepatocellular carcinoma mice
Zhili Liu, Zhen Lu, Bingfeng Zuo, Renwei Jing, Xianjun Gao, Gang Han, Han Qi, Li Wu, Yunde Liu, HaiFang Yin
Theranostics online date 2019-4-30; doi:10.7150/thno.32720; in press
[Author manuscript]

Heterologous and cross-species tropism of cancer derived extracellular vesicles
M. Garofalo, A. Villa, D. Crescenti, M. Marzagalli, L. Kuryk, P. Limonta, V. Mazzaferro, P. Ciana
Theranostics online date 2019-4-30; doi:10.7150/thno.34824; accepted
[Author manuscript]

Survey of the translation shifts in hepatocellular carcinoma with ribosome profiling
Qin Zou, Zhengtao Xiao, Rongyao Huang, Xin Wang, Xun Wang, Haitao Zhao, and Xuerui Yang
Theranostics online date 2019-4-30; doi:10.7150/thno.35033; in press
[Author manuscript]

The role of Nav1.7 and methylglyoxal-mediated activation of TRPA1 in itch and hypoalgesia in a murine model of type 1 diabetes
Ruo-Xiao Cheng, Yu Feng, Di Liu, Zhi-Hong Wang, Jiang-Tao Zhang, Li-Hua Chen, Cun-Jin Su, Bing Wang, Ya Huang, Ru-Rong Ji, Ji Hu, Tong Liu
Theranostics online date 2019-4-30; doi:10.7150/thno.36077; in press
[Author manuscript]

COL4A2 in the tissue-specific extracellular matrix plays important role on osteogenic differentiation of periodontal ligament stem cells
Yi Wen, Hongxu Yang, Junjie Wu, Axian Wang, Xiaodong Chen, Sijun Hu, Yuxing Zhang, Ding Bai, Zuolin Jin
Theranostics online date 2019-4-30; doi:10.7150/thno.35914; in press
[Author manuscript]

Chemiluminescence and Bioluminescence Imaging for Biosensing and Therapy: In Vitro and In Vivo Perspectives
Yongcun Yan, Pengfei Shi, Weiling Song, Sai Bi
Theranostics online date 2019-4-30; doi:10.7150/thno.33228; accepted
[Author manuscript]

Host-derived fecal microRNAs can indicate gut microbiota healthiness and ability to induce inflammation
Emilie Viennois, Benoit Chassaing, Anika Tahsin, Adani Pujada, Lixin Wang, Andrew T. Gewirtz and Didier Merlin
Theranostics online date 2019-4-30; doi:10.7150/thno.35282; accepted
[Author manuscript]

O-GlcNAc modification of Sox2 regulates self-renewal in pancreatic cancer by promoting its stability
Nikita S Sharma, Vineet K Gupta, Patricia Dauer, Kousik Kesh, Roey Hadad, Bhuwan Giri, Anjali Chandra, Vikas Dudeja, Chad Slawson, Santanu Banerjee, Selwyn M Vickers, Ashok Saluja and Sulagna Banerjee
Theranostics online date 2019-4-30; doi:10.7150/thno.32615; in press
[Author manuscript]

Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy
Lang Hu, Mingge Ding, Daishi Tang, Erhe Gao, Congye Li, Kaiyan Wang, Bingchao Qi, Jihuan Qiu, Huishou Zhao, Pan Chang, Feng Fu, Yan Li
Theranostics online date 2019-4-30; doi:10.7150/thno.33684; in press
[Author manuscript]

Laser brain cancer surgery guided by optical coherence tomography
Nitesh Katta, Arnold D Estrada, Austin B McElroy, Aleksandra Gruslova, Meagan Oglesby, Andrew G Cabe, Marc D Feldman, RY Declan Fleming, Andrew J Brenner, and Thomas E Milner
Theranostics online date 2019-4-30; doi:10.7150/thno.31811; in press
[Author manuscript]

SCARNA10, a nuclear-retained long non-coding RNA, promotes liver fibrosis and serves as a potential biomarker
Kun Zhang, Yawei Han, Zhimei Hu, ZhenZhang, Shuai Shao, QingbinYao, Lina Zheng, JingzhaoWang, XiaohuiHan, Yu Zhang, Ting Chen, Zhi Yao, Tao Han, Wei Hong
Theranostics online date 2019-4-30; doi:10.7150/thno.32935; in press
[Author manuscript]

Regularized reconstruction of digital time-of-flight 68Ga-PSMA-11 PET/CT for the detection of recurrent disease in prostate cancer patients
Elin Lindström; Irina Velikyan; Naresh Regula; Ali Alhuseinalkhudhur; Anders Sundin; Jens Sörensen; Mark Lubberink
Theranostics online date 2019-4-23; doi:10.7150/thno.31970; in press
[Author manuscript]

Molecularly annotation of mouse avatar models derived from patients with colorectal cancer liver metastasis
Jingyuan Wang, Baocai Xing, Wei Liu, Jian Li, Xicheng Wang, Juan Li, Jing Yang, Congcong Ji, Zhongwu Li, Bin Dong, Jing Gao, Lin Shen
Theranostics online date 2019-4-23; doi:10.7150/thno.32033; in press
[Author manuscript]

Disease-specific primed human adult stem cells effectively ameliorate experimental atopic dermatitis in mice
Byung-Chul Lee, Jae-Jun Kim, Jin Young Lee, Insung Kang, Nari Shin, Seung-Eun Lee, Soon Won Choi, Je-Yoel Cho, Hyung-Sik Kim, Kyung-Sun Kang
Theranostics online date 2019-4-23; doi:10.7150/thno.32945; in press
[Author manuscript]

Melatonin enhances sorafenib-induced cytotoxicity in FLT3-ITD acute myeloid leukemia cells by redox modification
Tian Tian, Jiajun Li, Yizhuo Li, Yun-Xin Lu, Yan-Lai Tang, Hua Wang, Fufu Zheng, Dingbo Shi, Qian Long, Miao Chen, Guillermo Garcia-Manero, Yumin Hu, Lijun Qin, Wuguo Deng
Theranostics online date 2019-4-23; doi:10.7150/thno.34327; in press
[Author manuscript]

Polo-Like Kinase 1 phosphorylates and stabilizes KLF4 to promote tumourigenesis in nasopharyngeal carcinoma
Jia Mai, Zhuo-Yan Zhong, Gui-Fang Guo, Xiu-Xing Chen, Yan-Qun Xiang, Xuan Li, Hai-Liang Zhang, Yu-Hong Chen, Xue-Lian Xu, Rui-Yan Wu, Yan Yu, Zhi-Ling Li, Xiao-Dan Peng, Yun Huang, Li-Huan Zhou, Gong-Kan Feng, Xiang Guo, Rong Deng, and Xiao-Feng Zhu
Theranostics online date 2019-4-30; doi:10.7150/thno.32908; in press
[Author manuscript]

A Combination of Oxo-M and 4-PPBP as a potential regenerative therapeutics for tendon injury
Solaiman Tarafder, Christopher Ricupero, Sumeet Minhas, Rebecca J. Yu, Ashleigh D. Alex, Chang H Lee
Theranostics online date 2019-4-23; doi:10.7150/thno.35285; in press
[Author manuscript]

Regulated Delayed Shigella flexneri 2a O-antigen Synthesis in Live Recombinant Salmonella enterica Serovar Typhimurium Induces Comparable Levels of Protective Immune Responses with Constitutive Antigen Synthesis System
Huali Su, Qing Liu, Shifeng Wang, Roy Curtiss III and Qingke Kong
Theranostics online date 2019-4-23; doi:10.7150/thno.33046; in press
[Author manuscript]

Current and future imaging methods for evaluating response to immunotherapy in neuro-oncology
Benjamin B. Kasten, Neha Udayakumar, Jianmei W. Leavenworth, Anna M. Wu, Suzanne E. Lapi, Jonathan E. McConathy, Anna G. Sorace, Asim K. Bag, James M. Markert, Jason M. Warram
Theranostics online date 2019-4-23; doi:10.7150/thno.34415; accepted
[Author manuscript]

Integration of metabolomics and expression of enolase-phosphatase 1 links to hepatocellular carcinoma progression
Hao Zhuang, Xiaowen Shao, Zhaoyan Qiang, Yamei Dang, Zun Wang, Fei Wu, Ping Fu, Wen Wei, Yongmei Li
Theranostics online date 2019-4-23; doi:10.7150/thno.31693; in press
[Author manuscript]

An in situ microenvironmental nano-regulator to inhibit the proliferation and metastasis of 4T1 tumor
Huijuan Zhang, Xiaoge Zhang, Yanping Ren, Fang Cao, Lin Hou, Zhenzhong Zhang
Theranostics online date 2019-4-23; doi:10.7150/thno.33141; in press
[Author manuscript]

Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease
Minghuan Wang, Chuan Qin, Xiang Luo, Jie Wang, Xuxia Wang, Minjie Xie, Jing Hu, Jie Cao, Ting Hu, Steven A. Goldman, Maiken Nedergaard, Wei Wang
Theranostics online date 2019-4-23; doi:10.7150/thno.31942; accepted
[Author manuscript]

Development of a stem cell tracking platform for ophthalmic applications using ultrasound and photoacoustic imaging
Kelsey P. Kubelick, Eric J. Snider, C. Ross Ethier, Stanislav Emelianov
Theranostics online date 2019-4-23; doi:10.7150/thno.32546; in press
[Author manuscript]

A Multifunctional Nanotherapy for Targeted Treatment of Colon Cancer by Simultaneously Regulating Tumor Microenvironment
Qixiong Zhang, Fuzhong Zhang, Shanshan Li, Renfeng Liu, Taotao Jin, Yin Dou, Zhenghua Zhou, Jianxiang Zhang
Theranostics online date 2019-4-23; doi:10.7150/thno.34377; in press
[Author manuscript]

Integrated microbiome and metabolome analysis reveals the novel interplay between commensal bacteria and metabolites in colorectal cancer
Yongzhi Yang, Biswapriya B. Misra, Lei Liang, Dexi Bi, Wenhao Weng, Wen Wu, Sanjun Cai, Huanlong Qin, Ajay Goel, Xinxiang Li, Yanlei Ma
Theranostics online date 2019-4-23; doi:10.7150/thno.35186; in press
[Author manuscript]

Circular RNAs negatively regulate cancer stem cells by physically binding FMRP against CCAR1 complex in hepatocellular carcinoma
Yan-Jing Zhu
Theranostics online date 2019-4-23; doi:10.7150/thno.32796; in press
[Author manuscript]

Precision medicine: circulating tumor cells as a tool for assessing tumor heterogeneity
Marta Tellez-Gabriel, Marie-Francoise Heymann, Dominique Heymann
Theranostics online date 2019-4-23; doi:10.7150/thno.34337; in press
[Author manuscript]

Nerve modulation therapy in gouty arthritis: targeting increased sFRP2 expression in dorsal root ganglion regulates macrophage polarization and alleviates endothelial damage
Jingtian Mei, Feng Zhou, Han Qiao, Hanjun Li, Tingting Tang
Theranostics online date 2019-4-23; doi:10.7150/thno.33908; in press
[Author manuscript]

Functionalization of SF/HAP Scaffold with GO-PEI-miRNA inhibitor Complexes to Enhance Bone Regeneration through Activating Transcription Factor 4
Lingling Ou a, Yong Lan b, Zhiqiang Feng a, Longbao Feng b, Junjie Yang a, Yu Liu c, Liming Bian d, Jiali Tan e, Renfa Lai a, Rui Guo f
Theranostics online date 2019-4-16; doi:10.7150/thno.34676; accepted
[Author manuscript]

Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo
Zhiwei Liao, Rongjin Luo, Gaocai Li, Yu Song, Shengfeng Zhan, Kangcheng Zhao, Wenbin Hua, Yukun Zhang, Xinghuo Wu and Cao Yang
Theranostics online date 2019-4-16; doi:10.7150/thno.33638; in press
[Author manuscript]

New insights into the pathogenesis and treatment of sarcopenia in chronic heart failure
Jiayu Yin, Xiang Lu, Zhiyuan Qian, Weiting Xu, Xiang Zhou
Theranostics online date 2019-4-16; doi:10.7150/thno.33000; in press
[Author manuscript]

One-step colorimetric genotyping of single nucleotide polymorphism using probe-enhanced loop-mediated isothermal amplification (PE-LAMP)
Sheng Ding, Rong Chen, Gangyi Chen, Mei Li, Jiayu Wang, Jiawei Zou, Feng Du, Juan Dong, Xin Cui, Xin Huang, Yun Deng and Zhuo Tang
Theranostics online date 2019-4-16; doi:10.7150/thno.33980; in press
[Author manuscript]

Blocking interleukin-6 trans-signaling protects against renal fibrosis by suppressing STAT3 activation
Wei Chen, Hui Yuan, Wenmin Cao, Tianwei Wang, Wei Chen, Hang Yu, Yao Fu, Bo Jiang, Hong Zhou, Hongqian Guo and Xiaozhi Zhao
Theranostics online date 2019-4-10; doi:10.7150/thno.32352; in press
[Author manuscript]

The m6A demethylase ALKBH5 controls trophoblast invasion at the maternal-fetal interface by regulating the stability of CYR61 mRNA
Xiao-Cui Li, Feng Jin, Pei-Ying Wang, Xiang-Jie Yin, Wei Hong, Fu-Ju Tian
Theranostics online date 2019-4-10; doi:10.7150/thno.31868; in press
[Author manuscript]

Gadolinium-Chelated Conjugated Polymer-Based Nanotheranostics for Photoacoustic/Magnetic Resonance/NIR-II Fluorescence Imaging-Guided Cancer Photothermal Therapy
Xiaoming Hu; Yufu Tang; Yuxuan Hu; Feng Lu; Xiaomei Lu; Yuqi Wang; Jie Li; Yuanyuan Li; Yu Ji; Wenjun Wang; Deju Ye; Quli Fan and Wei Huang
Theranostics online date 2019-4-10; doi:10.7150/thno.34390; in press
[Author manuscript]

Identification of a rhodanine derivative BML-260 as a potent stimulator of UCP1 expression
Zhuanghui Feng, Yuda Wei, Yongxian Zhang, Yan Qiu, Xiaojian Liu, Ningning Liang, Huiyong Yin, Qiurong Ding
Theranostics online date 2019-4-16; doi:10.7150/thno.31951; in press
[Author manuscript]

Rod-shape MSN@MoS2 Nanoplatform for FL/MSOT/CT Imaging-Guided Photothermal and Photodynamic Therapy
Lifang Yang, Jinping Wang, Shan Yang, Qianglan Lu, Peishan Li, Nan Li
Theranostics online date 2019-4-10; doi:10.7150/thno.32715; in press
[Author manuscript]

Impaired Regeneration Potential in Urinary Stem Cells Diagnosed from the Patients with Diabetic Nephropathy
Geng Xiong, Weiqing Tang, Deying Zhang, David He, Guanghui Wei, Xing-Jie Liang, Antony Atala, Anthony J. Bleyer, Michael E. Bleyer, Jie Yu, Joseph A. Aloi, Jian-Xing Ma, Cristina M. Furdui and Yuanyuan Zhang
Theranostics online date 2019-4-10; doi:10.7150/thno.34050; in press
[Author manuscript]

Clathrin-mediated Endocytosis of Alpha-1 Antitrypsin is Essential for its Protective Function in Islet Cell Survival-Version 2
Jingjing Wang, Wenyu Gou, Do-sung Kim, Charlie Strange, Hongjun Wang
Theranostics online date 2019-4-10; doi:10.7150/thno.31647; in press
[Author manuscript]

Determination of cerebrospinal fluid leakage by selective deletion of transferrin glycoform using an immunochromatographic assay
Jusung Oh, Seok-Joon Kwon, Jonathan S. Dordick, William J. Sonstein, Robert J. Linhardt, Min-Gon Kim
Theranostics online date 2019-4-16; doi:10.7150/thno.34411; in press
[Author manuscript]

Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome
Dapeng Hao, Jingjing Li, Jianlin Wang, Yuan Meng, Zhiqiang Zhao, Chao Zhang, Kai Miao, Chuxia Deng, Benjamin K. Tsang, Li Wang, Li-jun Di
Theranostics online date 2019-3-31; doi:10.7150/thno.30814; in press
[Author manuscript]

Prospective non-invasive evaluation of CXCR4 expression for diagnosis of MALT lymphoma using [68Ga]Ga-Pentixafor-PET/MRI
Alexander R. Haug, Asha Leisser, Wolfgang Wadsak, Markus Mitterhauser, Sarah Pfaff, S. Kropf, Hans-Juergen Wester, Marcus Hacker, Markus Hartenbach, Barbara Kiesewetter-Wiederkehr, Markus Raderer, Marius E. Mayerhoefer
Theranostics online date 2019-3-31; doi:10.7150/thno.31032; in press
[Author manuscript]

Spontaneous evolution of human skin fibroblasts into wound-healing keratinocyte-like cells
Fang Zhang, Dandan Zhang, Kai Cheng, Zaixin Zhou, Shupeng Liu, Liang Chen, Yijun Hu, Chuanbin Mao, and Shanrong Liu
Theranostics online date 2019-3-31; doi:10.7150/thno.31526; accepted
[Author manuscript]

Gold nanoparticles that target degraded elastin improve imaging and rupture prediction in an AngII mediated mouse model of abdominal aortic aneurysm
Xiaoying Wang, Brooks A. Lane, John F. Eberth, Susan M. Lessner, Naren R. Vyavahare
Theranostics online date 2019-3-31; doi:10.7150/thno.34441; in press
[Author manuscript]

Theranostic Application of Lipiodol for transarterial Chemoembolization in a VX2 Rabbit Liver Tumor Model
Johanna Maria Mijntje van Breugel, Jean-François Geschwind, Sahar Mirpour, Lynn Jeanette Savic, Xuchen Zang, Rafael Duran, MingDe Lin, Milena Miszczuk, Elena Liapi, Julius Chapiro
Theranostics online date 2019-3-28; doi:10.7150/thno.32943; in press
[Author manuscript]

Polydopamine coated multifunctional lanthanide theranostic agent for vascular malformation and tumor vessel imaging beyond 1500 nm and imaging-guided photothermal therapy
Xiaolong Li, Mingyang Jiang, Songjun Zeng, and Hongrong Liu
Theranostics online date 2019-3-27; doi:10.7150/thno.31864; in press
[Author manuscript]

Engineering temperature-sensitive plateletsomes as a tailored chemotherapy platform in combination with HIFU ablation for cancer treatment
Dongqi Wu, Xing Jin, Xiaobing Wang, Boyu Ma, Chenmei Lou, Haijing Qu, Jian Zheng, Binxuan Zhang, Xiufeng Yan, Yang Wang, Lijia Jing 
Theranostics online date 2019-3-27; doi:10.7150/thno.32172; in press
[Author manuscript]

Enhanced recruitment of tumor vasculature-specific cytotoxic T lymphocytes by endoglin aptamer and IP-10 plasmid presenting liposome-based nanocarriers
Xiaomei Yang, Jing Zhao, Siliang Duan, Xiaoqiong Hou, Xi Li, Zixi Hu, Zhuoran Tang, Fengzhen Mo, Xiaoling Lu
Theranostics online date 2019-3-25; doi:10.7150/thno.33383; in press
[Author manuscript]

Forkhead box K2 promotes human colorectal cancer metastasis by upregulating ZEB1 and EGFR
Feng Du, Chenyang Qiao, Xiaowei Li, Zhangqian Chen, Hao liu, Shengda Wu, Sijun Hu, Zhaoyan Qiu, Meirui Qian, Dean Tian, Kaichun Wu, Daiming Fan, Yongzhan Nie, Limin Xia
Theranostics online date 2019-3-25; doi:10.7150/thno.31716; in press
[Author manuscript]

A comprehensive study of vesicular and non-vesicular miRNAs from a volume of cerebrospinal fluid compatible with clinical practice
Endika Prieto-Fernandez, Ana Maria Aransay, Felix Royo, Esperanza Gonzalez, Juan Jose Lozano, Borja Santos-Zorrozua, Nuria Macias-Camara, Monika Gonzalez, Raquel Perez Garay, Javier Benito, Africa Garcia-Orad, Juan Manuel Falcon-Perez
Theranostics online date 2019-3-22; doi:10.7150/thno.31502; in press
[Author manuscript]

Rapamycin increases collateral circulation in the rodent brain after focal ischemia as detected by multiple modality dynamic imaging
Jixian Wang, Xiaojie Lin, Zhihao Mu, Fanxia Shen, Linyuan Zhang, Qing Xie, Yaohui Tang, Yongting Wang, Zhijun Zhang and Guo-Yuan Yang
Theranostics online date 2019-3-22; doi:10.7150/thno.32676; accepted
[Author manuscript]

Cysteine-type cathepsins promote the effector phase of acute cutaneous delayed-type hypersensitivity reactions
Johannes Schwenck, Andreas Maurer, Birgit Fehrenbacher, Roman Mehling, Philipp Knopf, Natalie Mucha, Dennis Haupt, Kerstin Fuchs, Christoph M. Griessinger, Daniel Bukala, Julia Holstein, Martin Schaller, Irene Gonzalez Menendez, Kamran Ghoreschi, Leticia Quintanilla-Martinez, Michael Gütschow, Stefan Laufer, Thomas Reinheckel, Martin Röcken, Hubert Kalbacher, Bernd J Pichler, Manfred Kneilling
Theranostics online date 2019-3-31; doi:10.7150/thno.31037; in press
[Author manuscript]

Temporal inhibition of mouse mammary gland cancer metastasis by CORM-A1 and DETA/NO combination therapy
Kseniia Porshneva, Diana Papiernik, Mateusz Psurski, Rafał Matkowski, Marcin Ekiert, Marcin Nowak, Joanna Jarosz, Joanna Banach, Magdalena Milczarek, Joanna Wietrzyk
Theranostics online date 2019-3-22; doi:10.7150/thno.31461; in press
[Author manuscript]

Hypoxia-induced feedback of HIF-1α and lncRNA-CF129 contributes to pancreatic cancer progression through stabilization mutant p53 protein
Mingliang Liu, Jianxin Zhong, Zhu Zeng, Kang Huang, Zeng Ye, Shijiang Deng, Hengyu Chen, Fengyu Xu, Qiang Li, Gang Zhao
Theranostics online date 2019-2-14; doi:10.7150/thno.30988; accepted
[Author manuscript]


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