Online advance articles

A novel TNF-a-targeting aptamer for TNF-a-mediated acute lung injury and acute liver failure
Wei-Yun Lai, Jen-Wei Wang, Bo-Tsang Huang, Emily Pei-Ying Lin, and Pan-Chyr Yang
Theranostics online date 2019-1-18; doi:10.7150/thno.30972; accepted
[Author manuscript]

Design strategies and application progress of therapeutic exosomes
Chunying Liu and Changqing Su
Theranostics online date 2019-1-18; doi:10.7150/thno.30853; accepted
[Author manuscript]

Tolerizing CTL by sustained hepatic PD-L1 expression provides a new therapy approach in mouse sepsis
A. von Knethen, A. Schäfer, L. Kuchler, T. Knape, U. Christen, E. Hintermann, B. Fißlthaler, K.Schröder, R.P. Brandes, B. Genz, K. Abshagen, B.M. Pützer, L.K. Sha, A. Weigert, S.N. Syed, M. Schulz, A.M. Shah, A. Ernst, M. Putyrski, F. Finkelmeier, M. Pesic, F. Greten, M, Hogardt, V.A.J. Kempf, S. Gunne, M.J. Parnham, B. Brüne
Theranostics online date 2019-1-18; doi:10.7150/thno.28057; accepted
[Author manuscript]

Preclinical efficacy of hK2 targeted [177Lu]hu11B6 for prostate cancer theranostics
Oskar Vilhelmsson Timmermand, Jörgen Elgqvist, Kai A. Beattie, Anders Örbom, Erik Larsson, Sophie E Eriksson, Daniel L.J. Thorek, Bradley J. Beattie, Thuy A. Tran, David Ulmert, Sven-Erik Strand
Theranostics online date 2019-1-18; doi:10.7150/thno.31179; accepted
[Author manuscript]

Identification of miR-29c and its target FBXO31 as key regulatory mechanism in esophageal cancer chemoresistance-functional validation and clinical significance
Bin Li, Pan Hong, Can-Can Zheng, Wei Dai, Wen-You Chen, Qing-Sheng Yang, Liang Han, Sai Wah Tsao, Kin Tak Chan, Nikki Pui Yue Lee, Simon Law, Li Yan Xu, En Min Li, Kwok Wah Chan, Yan Ru Qin, Xin Yuan Guan, Maria Li Lung, Qing-Yu He, Wen Wen Xu, Annie LM Cheung
Theranostics online date 2019-1-18; doi:10.7150/thno.30372; accepted
[Author manuscript]

p66Shc contributes to liver fibrosis through the regulation of mitochondrial reactive oxygen species
Yan Zhao, Zhecheng Wang, Dongcheng Feng, Huanyu Zhao, Musen Lin, Yan Hu, Ning Zhang, Li Lv, Zhenming Gao, Xiaohan Zhai, Xiaofeng Tian, Jihong Yao
Theranostics online date 2019-1-18; doi:10.7150/thno.29620; accepted
[Author manuscript]

Circulating proteomic panels for diagnosis and risk stratification of acute-on-chronic liver failure in patients with viral hepatitis B
Zeyu Sun, Xiaoli Liu, Daxian Wu, Hainv Gao, Jing Jiang, Ying Yang, Jie Wu, Qikang Gao, Jie Wang, Zhengyi Jiang, Youping Xu, Xiao Xu & Lanjuan Li
Theranostics online date 2019-1-18; doi:10.7150/thno.31991; accepted
[Author manuscript]

Genome-wide profiling of Epstein-Barr virus integration by targeted sequencing in Epstein-Barr virus associated malignancies
Miao XuWei-Long ZhangQing ZhuYouyuan YaoQi-Sheng FengZhe Zhang Rou-Jun Peng Wei-Hua JiaGui-Ping He, Lin FengZhao-Lei Zeng Bing LuoRui-Hua XuMu-Sheng ZengWei-Li ZhaoSai-Juan ChenYi-Xin ZengYuchen Jiao
Theranostics online date 2019-1-18; doi:10.7150/thno.29622; accepted
[Author manuscript]

Polymerase Chain Reaction using “V” Shape thermal cycling program
Rong Chen, Xue Lu, Mei Li, Gangyi Chen, Yun Deng, Feng Du, Juan Dong, Xin Huang, Xin Cui, Zhuo Tang
Theranostics online date 2019-1-15; doi:10.7150/thno.31986; accepted
[Author manuscript]

Microporous polysaccharide multilayer coated BCP composite scaffolds with immobilised calcitriol promote osteoporotic bone regeneration both in vitro and in vivo
Qian Tang, Zhichao Hu, Haiming Jin, Gang Zheng, XingFang Yu, Gang Wu, Haixiao Liu, Zhenzhong Zhu, Huazi Xu, Changqing Zhang, Liyan Shen
Theranostics online date 2019-1-15; doi:10.7150/thno.29566; in press
[Author manuscript]

Therapeutic effects of human monoclonal PSMA antibody-mediated TRIM24 siRNA delivery in PSMA-positive castration-resistant prostate cancer
Sheng-Jia Shi, Li-Juan Wang, Dong-Hui Han, Jie-Heng Wu, Dian Jiao, Kai-Liang Zhang, Jiang-Wei Chen, Yu Li, Fa Yang, Jing-Liang Zhang, Guo-Xu Zheng, An-Gang Yang, Ai-Zhi Zhao, Wei-Jun Qin, Wei-Hong Wen
Theranostics online date 2019-1-15; doi:10.7150/thno.29884; in press
[Author manuscript]

Berberine protects glomerular podocytes via the inhibition of Drp1-mediated mitochondrial fission and dysfunction
Xin Qin, Yan Zhao, Jing Gong, Wenya Huang, Hao Su, Fen Yun, Ke Fang, Dingkun Wang, Jingbin Li, Xin Zou, Lijun Xu, Hui Dong, Fuer Lu
Theranostics online date 2019-1-15; doi:10.7150/thno.30640; accepted
[Author manuscript]

Tumor-secreted dickkopf2 accelerates aerobic glycolysis and promotes angiogenesis in clorectal cancer
Fengliu Deng, Rui Zhou, Chuang Lin, Shibin Yang, Hui Wang, Weidong Li, Kehong Zheng, Wandie Lin, Xin Li, Xueqing Yao, Mingxin Pan, Liang Zhao
Theranostics online date 2019-1-15; doi:10.7150/thno.30056; in press
[Author manuscript]

Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN
Qitong Zhang, Qingquan Zhang, Xue Jiang, Youqiong Ye, Huimin Liao, Fugui Zhu, Jie Yan, Lina Luo, Li Tian, Cizhong Jiang, Yihan Chen, Xingqun Liang, Yunfu Sun
Theranostics online date 2019-1-15; doi:10.7150/thno.30199; in press
[Author manuscript]

Immune targets in the tumor microenvironment treated by radiotherapy
Omer M. Ozpiskin, Lu Zhang, and Jian Jian Li
Theranostics online date 2019-1-15; doi:10.7150/thno.32648; accepted
[Author manuscript]

Interaction between p53 and Ras signaling controls cisplatin resistance via HDAC4- and HIF-1α-mediated regulation of apoptosis and autophagy
Xiaofei Zhang, Zihao Qi, Huijing Yin, Gong Yang
Theranostics online date 2019-1-11; doi:10.7150/thno.29673; in press
[Author manuscript]

A blood-based multi marker assay supports the differential diagnosis of early-stage pancreatic cancer
Andreas W. Berger, Daniel Schwerdel, Anke Reinacher-Schick, Waldemar Uhl, Hana Algül, Helmut Friess, Klaus-Peter Janssen, Alexander König, Michael Ghadimi, Eike Gallmeier, Detlef K. Bartsch, Michael Geissler, Ludger Staib, Andrea Tannapfel, Alexander Kleger, Alica Beutel, Lucas-Alexander Schulte, Marko Kornmann, Thomas J. Ettrich, Thomas Seufferlein
Theranostics online date 2019-1-11; doi:10.7150/thno.29247; accepted
[Author manuscript]

The Applications of Radiomics in Precision Diagnosis and Treatment of Oncology: Opportunities and Challenges
Zhenyu Liu, Shuo Wang, Di Dong, Jingwei Wei, Xuezhi Zhou, Kai Sun, Longfei Li, Bo Li, Meiyun Wang, Jie Tian
Theranostics online date 2019-1-11; doi:10.7150/thno.30309; in press
[Author manuscript]

A logic-gated modular nanovesicle enables programmable drug release for on-demand chemotherapy
Longguang Tang, Zhen Yang, Zijian Zhou, Ying Ma, Dale O. Kiesewetter, Zhantong Wang, Wenpei Fan, Shoujun Zhu, Mingru Zhang, Rui Tian, Lixin Lang, Gang Niu, Xianzhong Zhang, and Xiaoyuan Chen
Theranostics online date 2019-1-11; doi:10.7150/thno.32106; in press
[Author manuscript]

ClC-7 regulates the pattern and early development of craniofacial bone and tooth
Yanli Zhang, Dongrui Ji, Lin Li, Shaoqing Yang, Hengwei Zhang, Xiaohong Duan
Theranostics online date 2019-1-9; doi:10.7150/thno.29761; accepted
[Author manuscript]

An optogenetic controllable T cell system for hepatocellular carcinoma immunotherapy
Bixing Zhao, Yingchao Wang, Xionghong Tan, Xiaoyuan Zheng, Fei Wang, Kun Ke, Cuilin Zhang, Naishun Liao, Yuan Dang, Yingjun Shi, Youshi Zheng, Yunzhen Gao, Qin Li, Xiaolong Liu, Jingfeng Liu
Theranostics online date 2019-1-9; doi:10.7150/thno.27051; accepted
[Author manuscript]

Nanoliposomes co-encapsulating a CT imaging contrast agent and photosensitizer for enhanced, imaging guided photodynamic therapy of cancer
Hao Xu, Tymish Y. Ohulchanskyy, Artem Yakovliev, Roman Zinyuk, Jun Song, Liwei Liu, Junle Qu, Zhen Yuan
Theranostics online date 2019-1-8; doi:10.7150/thno.31079; in press
[Author manuscript]

Evaluation of polymer nanoformulations in hepatoma therapy by established rodent models
Qilong Wang, Ping Zhang, Zhongmin Li, Xiangru Feng, Chengyue Lv, Huaiyu Zhang, Haihua Xiao, Jianxun Ding, Xuesi Chen
Theranostics online date 2019-1-8; doi:10.7150/thno.31683; accepted
[Author manuscript]

The search for an alternative to [68Ga]Ga-DOTA-TATE in neuroendocrine tumor theranostics: current state of 18F-labeled somatostatin analog development
Christopher M. Waldmann, Andreea D. Stuparu, R. Michael van Dam, Roger Slavik
Theranostics online date 2019-1-15; doi:10.7150/thno.31806; in press
[Author manuscript]

Molecular imaging of immune cell dynamics during de- and remyelination in the cuprizone model of multiple sclerosis by [18F]DPA-714 PET and MRI [RESUBMISSION]
Bastian Zinnhardt, Michaël Belloy, Inga B. Fricke, Jasmien Orije, Caroline Guglielmetti, Sven Hermann, Stefan Wagner, Michael Schäfers, Annemie Van der Linden, and Andreas H. Jacobs
Theranostics online date 2019-1-8; doi:10.7150/thno.32461; accepted
[Author manuscript]

Exosomes from M1-polarized macrophages enhance paclitaxel antitumor activity by activating macrophages-mediated inflammation
Piaopiao Wang, Huihui Wang, Qianqian Huang, Can Peng, Liang Yao, Hong Chen, Zhen Qiu, Yifan Wu, Lei Wang, and Weidong Chen
Theranostics online date 2019-1-8; doi:10.7150/thno.30716; accepted
[Author manuscript]

Convection-Enhanced Delivery of a Virus-Like Nanotherapeutic Agent with Dual-Modal Imaging for Besiegement and Eradication of Brain Tumors
Hao-Han Pang, Pin-Yuan Chen, Kuo-Chen Wei, Chiun-Wei Huang, Yow-Ling Shiue, Chiung-Yin Huang, Hung-Wei Yang
Theranostics online date 2019-1-6; doi:10.7150/thno.30977; accepted
[Author manuscript]

H2Se induces reductive stress in HepG2 cells and activates cell autophagy by regulating the redox of HMGB1 protein under hypoxia
Xiaohong Pan, Xiaoxiao Song, Cheng Wang, Tingting Cheng, Dongrui Luan, Kehua Xu, and Bo Tang
Theranostics online date 2019-1-18; doi:10.7150/thno.31841; accepted
[Author manuscript]

Synthesis of enantiopure 18F-trifluoromethyl cysteine as a structure-mimetic amino acid tracer for glioma imaging
Shaoyu Liu, Hui Ma, Zhanwen Zhang, Liping Lin, Gongjun Yuan, Xiaolan Tang, Dahong Nie, Shende Jiang, Guang Yang, and Ganghua Tang
Theranostics online date 2019-1-6; doi:10.7150/thno.29405; in press
[Author manuscript]

Real-time monitoring of pharmacokinetics of antibiotics in biofilms with Raman-tagged hyperspectral stimulated Raman scattering microscopy
Kideog Bae, Wei Zheng, Ying Ma, Zhiwei Huang
Theranostics online date 2019-1-6; doi:10.7150/thno.32043; in press
[Author manuscript]

Silk fibroin-coated nanoagents for acidic lysosome targeting by a functional preservation strategy in cancer chemotherapy
Mixiao Tan, Weiwei Liu, Fengqiu Liu, Wei Zhang, Hui Gao, Juan Cheng, Yu Chen, Zhigang Wang, Yang Cao and Haitao Ran
Theranostics online date 2019-1-8; doi:10.7150/thno.30765; in press
[Author manuscript]

Nano-structural effects on gene transfection: large, botryoid-shaped nanoparticles enhance DNA delivery via macropinocytosis and effective dissociation
Wenyuan Zhang, Xuejia Kang, Bo Yuan, Tao Zhang, Mingjie Shi, Zening Zheng, Yuanheng Zhang, Chengyuan Peng, Xiaoming Fana, Huiyuan Wang, Youqing Shen, Yongzhuo Huang
Theranostics online date 2019-1-6; doi:10.7150/thno.30302; accepted
[Author manuscript]

Radioembolization of Hepatocellular Carcinoma with Built-In Dosimetry: First In Vivo Results with Uniformly-Sized, Biodegradable Microspheres Labeled with 188Re
José Carlos De La Vega, Pedro Luis Esquinas, Cristina Rodríguez-Rodríguez, Mehrdad Bokharaei, Igor Moskalev, David Liu, Katayoun Saatchi, and Urs O. Häfeli
Theranostics online date 2019-1-2; doi:10.7150/thno.29381; in press
[Author manuscript]

Serum miR-626 and miR-5100 are promising prognosis predictors for oral squamous cell carcinoma
Qin Xu
Theranostics online date 2019-1-2; doi:10.7150/thno.30339; in press
[Author manuscript]

Nrf2 signaling and inflammation are key events in physical plasma-spurred wound healing
Anke Schmidt, Thomas von Woedtke, Brigitte Vollmar, Sybille Hasse, Sander Bekeschus
Theranostics online date 2019-1-2; doi:10.7150/thno.29754; in press
[Author manuscript]

Pseurotin A inhibits osteoclastogenesis and prevents ovariectomized-induced bone loss by suppressing reactive oxygen species
Kai Chen, Pengcheng Qiu, Yu Yuan, Lin Zheng, Jianbo He, Chao Wang, Qiang Guo, Jacob Kenny, Qian Liu, Jingmin Zhao, Junhao Chen, Jennifer Tickner, Shunwu Fan, Xianfeng Lin, Jiake Xu
Theranostics online date 2019-1-2; doi:10.7150/thno.30206; accepted
[Author manuscript]

Near infrared imaging of epidermal growth factor receptor positive xenografts in mice with domain I/II specific antibody fragments
Wendy Bernhard, Ayman El-Sayed, †, Kris Barreto, †, Carolina Gonzalez, Humphrey Fonge, Clarence Ronald Geyer
Theranostics online date 2019-1-2; doi:10.7150/thno.30835; accepted
[Author manuscript]

Nanoparticle binding to urokinase receptor on cancer cell surface triggers nanoparticle disintegration and cargo release
Shijie Li, Cai Yuan, Jincan Chen, Dan Chen, Zhuo Chen, Wenlie Chen, Shufeng Yan, Ping Hu, Jinping Xue, Rui Li, Ke Zheng, Mingdong Huang
Theranostics online date 2019-1-2; doi:10.7150/thno.29445; in press
[Author manuscript]

MMP-2-Controlled Transforming Micelles for Heterogeneic Targeting and Programmable Cancer Therapy
Zihua Wang, Yuehua Wang, Xiangqian Jia, Qiuju Han, Yixia Qian, Qian Li, Junfeng Xiang, Qian Wang, Zhiyuan Hu and Weizhi Wang
Theranostics online date 2019-1-2; doi:10.7150/thno.30915; accepted
[Author manuscript]

GRP78-targeted ferritin nanocaged ultra-high dose of doxorubicin for hepatocellular carcinoma therapy
Bing Jiang, Ruofei Zhang, Jianlin Zhang, Yaxin Hou, Xuehui Chen, Meng Zhou, Xiuyun Tian, Chunyi Hao, Kelong Fan, and Xiyun Yan
Theranostics online date 2019-1-2; doi:10.7150/thno.30867; accepted
[Author manuscript]

CircHMGCS1 promotes hepatoblastoma cell proliferation by regulating the IGF signaling pathway and glutaminolysis
Ni Zhen, Song Gu, Ji Ma, Jiabei Zhu, Min Xu, Minzhi Yin, Jing Wang, Zhixuan Bian, Fenyong Sun and Qiuhui Pan
Theranostics online date 2019-1-2; doi:10.7150/thno.29515; in press
[Author manuscript]

Fto deficiency reduces anxiety- and depression-like behaviors in mice via alterations in gut microbiota
Lijuan Sun, Lanjing Ma, Haohao Zhang, Ying Cao, Chenchen wang, Nannan Hou, Niu Huang, Karen M. von Deneen, Changhai Zhao, Yupeng Shi, Yan Pan, Meixia Wang, Gang Ji, Yongzhan Nie
Theranostics online date 2018-12-28; doi:10.7150/thno.31562; in press
[Author manuscript]

Using near-infrared enhanced thermozyme and scFv dual-conjugated Au nanorods for detection and targeted photothermal treatment of Alzheimer’s disease
Dongni Liu, Wei Li, Xiaoyu Jiang, Shuju Bai, Jiyang Liu, Xutong Liu, Yuhua Shi, Ziyu Kuai, Wei Kong, Renjun Gao, and Yaming Shan
Theranostics online date 2018-12-28; doi:10.7150/thno.30649; in press
[Author manuscript]

Zwitterionic near-infrared fluorophore-conjugated epidermal growth factor for fast, real-time, and target-cell-specific cancer imaging
Hyunjin Kim, Mi Hyeon Cho, Hak Soo Choi, Yongdoo Choi
Theranostics online date 2018-12-28; doi:10.7150/thno.29719; in press
[Author manuscript]

Enhanced therapeutic effect of RGD-modified polymeric micelles loaded with low-dose methotrexate and nimesulide on rheumatoid arthritis
Yunlong Wang, Zhongbing Liu, Ting Li, Lin Chen, Jiayao Lyu, chunhong Li, Yan Lin, Na Hao, Meiling Zhou, Zhirong Zhong
Theranostics online date 2018-12-28; doi:10.7150/thno.30418; in press
[Author manuscript]

Agonist c-Met monoclonal antibody augments the proliferation of hiPSC-derived hepatocyte-like cells and improves cell transplantation therapy for liver failure in mice
Lunzhi Yuan, Yali Zhang, Xuan Liu, Yao Chen, Liang Zhang, Jiali Cao, Xiaoling Li, Mingfeng Wang, Kun Wu, Jun Zhang, Gang Liu, Qiyi Tang, Quan Yuan, Tong Cheng, and Ningshao Xia
Theranostics online date 2018-12-28; doi:10.7150/thno.30009; accepted
[Author manuscript]

Mitochondria-responsive drug release along with heat shock mediated by multifunctional glycolipid micelles for precise cancer chemo-phototherapy
Yanan Tan, Yun Zhu, Lijuan Wen, Xiqin Yang, Xuan Liu, Tingting Meng, Suhuan Dai, Yuan Ping, Hong Yuan, and Fuqiang Hu
Theranostics online date 2018-12-28; doi:10.7150/thno.31022; in press
[Author manuscript]

Transcriptional downregulation of miR-4306 serves as a new therapeutic target for triple negative breast cancer
Zitong Zhao, Lin Li, Peina Du, Liying Ma, Weimin Zhang, Leilei Zheng, Bo Lan, Bailin Zhang, Fei Ma, Bo Xu, Qimin Zhan, Yongmei Song
Theranostics online date 2018-12-28; doi:10.7150/thno.30701; accepted
[Author manuscript]

Spatial distribution of motor endplates and its adaptive change in skeletal muscle
Xiaofeng Yin, Tingting Yu, Bo Chen, Jianyi Xu, Wentao Chen, Yisong Qi, Peixun Zhang, Yusha Li, Yuhui Kou, Yiling Ma, Na Han, Peng Wan, Qingming Luo, Dan Zhu, Baoguo Jiang
Theranostics online date 2018-12-28; doi:10.7150/thno.28729; in press
[Author manuscript]

Absence of GdX/UBL4A protects against inflammatory diseases by regulating NF-кB signaling in macrophages and dendritic cells
Chunxiao Liu, Yifan Zhou, Mengdi Li, Ying Wang, Liu Yang, Shigao Yang, Yarui Feng, Yinyin Wang, Yangmeng Wang, Fangli Ren, Jun Li, Zhongjun Dong, Y. Eugene Chin, Xinyuan Fu, Li Wu, Zhijie Chang
Theranostics online date 2018-12-23; doi:10.7150/thno.32451; in press
[Author manuscript]

TBC1D8 amplification drives ovarian cancer metabolism reprogramming and tumorigenesis
Min Chen, Xiu-Jie Sheng, Yuan-Yi Qin, Song Zhu, Qing-Xia Wu, Liqing Jia, Nan Meng, Yu-Tian He, Guang-Rong Yan
Theranostics online date 2018-12-28; doi:10.7150/thno.30224; in press
[Author manuscript]

Targeted drug delivery and image-guided therapy of heterogeneous ovarian cancer using HER2-targeted theranostic nanoparticles
Minati Satpathy, Liya Wang, Rafal J. Zielinski, Weiping Qian, Y. Andrew Wang, Aaron Mohs, Brad A. Kairdolf, Xin Ji, Jacek Capala, Malgorzata Lipowska, Shuming Nie, Hui Mao, and Lily Yang
Theranostics online date 2018-12-23; doi:10.7150/thno.29964; in press
[Author manuscript]

IONF@CuS nanohybrids for cancer tri-therapy: interplay of photothermal therapy, magnetic hyperthermia and photodynamic therapy
Alberto Curcio, Amanda K. A. Silva, Sonia Cabana, Ana Espinosa, Benoit Baptiste, Nicolas Menguy, Claire Wilhelm, Ali Abou-Hassan
Theranostics online date 2019-1-2; doi:10.7150/thno.30238; in press
[Author manuscript]

GSH-sensitive Pt(IV) prodrug-loaded phase-transitional nanoparticles with a hybrid lipid-polymer shell for precise theranostics against ovarian cancer
Hui Huang, Yang Dong, Yanhua Zhang, Dan Ru, Zhihua Wu, Jiali Zhang, Ming Shen, Ying Sun, and Yourong Duan
Theranostics online date 2019-1-2; doi:10.7150/thno.29820; in press
[Author manuscript]

A synthetic receptor as a specific antidote for paraquat poisoning
Xiangjun Zhang, Xiaoqiu Xu, Shengke Li, Lanlan Li, Jianxiang Zhang and Ruibing Wang
Theranostics online date 2018-12-23; doi:10.7150/thno.31485; in press
[Author manuscript]

Drug repositioning inferred from E2F1-coregulator interactions studies for the prevention and treatment of metastatic cancers
Deborah Goody, Shailendra K. Gupta, David Engelmann, Alf Spitschak, Stephan Marquardt, Stefan Mikkat, Claudia Meier, Charlotte Hauser, Jan-Paul Gundlach, Jan-Hendrik Egberts, Hubert Martin, Toni Schumacher, Anna Trauzold, Olaf Wolkenhauer, Stella Logotheti, Brigitte M. Pützer
Theranostics online date 2018-12-23; doi:10.7150/thno.29546; accepted
[Author manuscript]

Upconversion-magnetic Carbon Sphere for Near-infrared Light Triggered Bioimaging and Photothermal Therapy
Jiaxin Wang, Chenjie Yao, Bin Shen, Xiaohui Zhu, Yong Li, Liyi Shi, Yong Zhang, Jinliang Liu, Yanli Wang, Lining Sun
Theranostics online date 2018-12-23; doi:10.7150/thno.27952; in press
[Author manuscript]

RACK1 promotes self-renewal and chemoresistance of cancer stem cells in human hepatocellular carcinoma through stabilizing Nanog
Junxia Cao, Min Zhao, Jian Liu, Xueying Zhang, Yujun Pei, Jingyang Wang, Xiao Yang, Beifen Shen, Jiyan Zhang
Theranostics online date 2018-12-23; doi:10.7150/thno.29271; in press
[Author manuscript]

Targeting anthrax toxin receptor 2 ameliorates endometriosis progression
Shih-Chieh Lin, Hsiu-Chi Lee, Ching-Ting Hsu, Yi-Han Huang, Wan-Ning Li, Pei-Ling Hsu, Meng-Hsing Wu, and Shaw-Jenq Tsai
Theranostics online date 2018-12-23; doi:10.7150/thno.30655; in press
[Author manuscript]

Activated platelets in the tumor microenvironment for targeting of antibody-drug-conjugates to tumors and metastases
May Lin Yap, James D McFadyen, Xiaowei Wang, Melanie Ziegler, Yung-Chih Chen, Abbey Willcox, Cameron J Nowell, Andrew M Scott, Erica K Sloan, P Mark Hogarth, Geoffrey A Pietersz, Karlheinz Peter
Theranostics online date 2019-1-15; doi:10.7150/thno.29146; in press
[Author manuscript]

Lectin-mediated pH-sensitive doxorubicin prodrug for pre-targeted chemotherapy of colorectal cancer with enhanced efficacy and reduced side effects
Meinan Yao, Xiaotu Ma, Xin Zhang, Linqing Shi, Tianyu Liu, Xiaolong Liang, Huiyun Zhao, Xiaoda Li, Liqiang Li, Hannan Gao, Bing Jia, Fan Wang
Theranostics online date 2018-12-23; doi:10.7150/thno.29989; in press
[Author manuscript]

Quantification of Human Neuromuscular Function through Optogenetics
Olaia F. Vila, Sebastien G.M. Uzel, Stephen P. Ma, Damian Williams, Roger D. Kamm and Gordana Vunjak-Novakovic
Theranostics online date 2018-12-28; doi:10.7150/thno.25735; in press
[Author manuscript]

MicroRNA-23a-3p inhibits mucosal melanoma growth and progression through targeting adenylate cyclase 1 and attenuating cAMP and MAPK pathways
Meng Ma, Jie Dai, Huan Tang, Tianxiao Xu, Sifan Yu, Lu Si, Chuanliang Cui, Xinan Sheng, Zhihong Chi, Lili Mao, Xiaowen Wu, Lu Yang, Huan Yu, Siming Li, Bin Lian, Bixiang Tang, Xuan Wang, Xieqiao Yan, Xue Bai, Li Zhou, Yan Kong, Jun Guo
Theranostics online date 2018-12-28; doi:10.7150/thno.30516; in press
[Author manuscript]

Epigenetic co-deregulation of EZH2/TET1 is a senescence-countering, actionable vulnerability in triple-negative breast cancer
Yong Yu, Jingjing Qi, Jieyi Xiong, Liping Jiang, Di Cui, Junlin He, Ping Chen, Lianjie Li, Chenjie Wu, Tonghui Ma, Su Shao, Jianjun Wang, Dansong Yu, Bing Zhou, Dongsheng Huang, Clemens A. Schmitt, Ran Tao
Theranostics online date 2018-12-28; doi:10.7150/thno.29520; in press
[Author manuscript]

LINC01554-mediated glucose metabolism reprogramming suppresses tumorigenicity in hepatocellular carcinoma via downregulating PKM2 expression and inhibiting Akt/mTOR signaling pathway
Yin-Li Zheng, Lei Li, Yong-Xun Jia, Bao-Zhu Zhang, Jiang-Chao Li, Ying-Hui Zhu, Meng-Qing Li, Jiao-Zi He, Ting-Ting Zeng, Xiao-Jiao Ban, Yun-Fei Yuan, Yan Li, Xin-Yuan Guan
Theranostics online date 2018-12-28; doi:10.7150/thno.28992; in press
[Author manuscript]

Imaging Fibrosis in Inflammatory Diseases: Targeting Exposed Extracellular Matrix
Nicolas Beziere, Kerstin Fuchs, Andreas Maurer, Gerald Reischl, Jürgen Brück, Kamran Ghoreschi, Daniel Carvajal Berrio, Katja Schenke-Layland, Ursula Kohlhofer, Leticia Quintanilla-Martinez, Meinrad Gawaz, Manfred Kneilling, Bernd Pichler
Theranostics online date 2018-12-23; doi:10.7150/thno.28892; accepted
[Author manuscript]

Monoclonal antibody against CXCL1 (HL2401) as a novel agent in suppressing IL6 expression and tumoral growth
Makito Miyake, Hideki Furuya, Sayuri Onishi, Kanani Hokutan, Satoshi Anai, Owen Chan, Sixiang Shi, Kiyohide Fujimoto, Steve Goodison, Weibo Cai, Charles J. Rosser
Theranostics online date 2018-12-28; doi:10.7150/thno.29553; in press
[Author manuscript]

Quantitative MALDI imaging of spatial distributions and dynamic changes of tetrandrine in multiple organs of rats
Weiwei Tang, Jun Chen, Jie Zhou, Junyue Ge, Ying Zhang, Ping Li, Bin Li
Theranostics online date 2018-12-28; doi:10.7150/thno.30408; in press
[Author manuscript]

Microfluidic isolation of circulating tumor cells and cancer stem-like cells from patients with pancreatic ductal adenocarcinoma
Jose I. Varillas, Jinling Zhang, Kangfu Chen, Isis I. Barnes, Chen Liu, Thomas J. George, and Z. Hugh Fan
Theranostics online date 2018-12-28; doi:10.7150/thno.28745; accepted
[Author manuscript]

Nuclear entry of CRTC1 as druggable target of acquired pigmentary disorder
Cheong-Yong Yun, Seung Deok Hong, Young Hee Lee, Jiyeon Lee, Da-Eun Jung, Ga Hyun Kim, Song-Hee Kim, Jae-Kyung Jung, Ki Ho Kim, Heesoon Lee, Jin Tae Hong, Sang-Bae Han, Youngsoo Kim
Theranostics online date 2018-12-28; doi:10.7150/thno.30276; in press
[Author manuscript]

Abnormal mTORC1 signaling leads to retinal pigment epithelium (RPE) degeneration
Jiancheng Huang, Shun Gu, Meng Chen, Shu-jie Zhang, Zhichun Jiang, Xue Chen, Chao Jiang, Guohua Liu, Roxana A Radu, Xiantao Sun, Douglas Vollrath, Jianhai Du, Biao Yan, Chen Zhao
Theranostics online date 2018-12-28; doi:10.7150/thno.26281; in press
[Author manuscript]

Anti-EGF receptor aptamer-guided co-delivery of anti-cancer siRNAs and quantum dots for theranosis of triple negative breast cancer
Min Woo Kim, Hwa Yeon Jeong, Seong Jae Kang, In Ho Jeong, Moon Jung Choi, Young Myoung You, Chan Su Im, In Ho Song, Tae Sup Lee, Jin Suk Lee, Aeju Lee and Yong Serk Park
Theranostics 2019; doi:10.7150/thno.30228; in press
[Author manuscript]

Human parthenogenetic neural stem cell grafts promote multiple regenerative processes in traumatic brain injury model
Jea-Young Lee, Sandra Acosta, Julian P. Tuazon, Kaya Xu, Hung Nguyen, Trenton Lippert, Michael G. Liska, Andrey Semechkin, Ibon Garitaonandia, Rodolfo Gonzalez, Russell Kern, Cesario V. Borlongan
Theranostics online date 2018-12-23; doi:10.7150/thno.29868; in press
[Author manuscript]

Molecular Imaging of Factor XIII Activity for the Early Detection of Mouse Coronary Microvascular Disease
Zhen W. Zhuang, Yang Huang, Rong Ju, Mark W. Maxfield, Yongming Ren, Xiangning Wang, Xinlu Wang, Mitchel R. Stacy, John Hwa
Theranostics online date 2018-12-23; doi:10.7150/thno.29255; accepted
[Author manuscript]

On the lipophilic nature of the autoreactive IgE in chronic spontaneous urticaria
Elisa Lakin, Martin K. Church, PhD DSc, Marcus Maurer, MD, Oliver Schmetzer, PhD MD
Theranostics online date 2018-12-23; doi:10.7150/thno.29902; in press
[Author manuscript]

Theranostic Nanodots with Aggregation-Induced Emission Characteristic for Targeted and Image-Guided Photodynamic Therapy of Hepatocellular Carcinoma
Yang Gao, Qi Chang Zheng, Shidang Xu, Youyong Yuan, Xiang Cheng, Shuai Jiang, Kenry, Qihong Yu, Zifang Song, Bin Liu, Min Li
Theranostics online date 2018-12-23; doi:10.7150/thno.29101; accepted
[Author manuscript]

Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5
Sandy Giuliano, Maeva Dufies, Papa Diogop Ndiaye, Julien Viotti, Delphine Borchiellini, Julien Parola, Valérie Vial, Yann Cormerais, Mickaël Ohanna, Véronique Imbert, Emmanuel Chamorey, Nathalie Rioux-Leclercq, Ariel Savina, Jean-Marc Ferrero, Baharia Mograbi, and Gilles Pagès
Theranostics online date 2018-12-23; doi:10.7150/thno.29093; accepted
[Author manuscript]

Membrane radiolabelling of exosomes for comparative biodistribution analysis in immunocompetent and immunodeficient mice – a novel and universal approach
Farid N. Faruqu, Julie Tzu-Wen Wang, Lizhou Xu, Luke McNickle, Eden Ming-Yiu Chong, Adam Walters, Mark Gurney, Aled Clayton, Lesley A. Smyth, Robert Hider, Jane Sosabowski, Khuloud T. Al-Jamal
Theranostics online date 2018-12-23; doi:10.7150/thno.27891; accepted
[Author manuscript]

Highly sensitive quantification of Alzheimer’s Disease biomarkers by aptamer-assisted amplification
Hei-Nga Chan, Di Xu, See-Lok Ho, Dinggeng He, Man Shing Wong, Hung-Wing Li
Theranostics online date 2018-12-23; doi:10.7150/thno.29232; accepted
[Author manuscript]

VEGFC: a double-edged sword in the aggressiveness of renal cell carcinoma
Papa Diogop Ndiaye, Maeva Dufies, Sandy Giuliano, Laetitia Douguet, Renaud Grépin, Jérôme Durivault, Philippe Lenormand, Natacha Glisse, Janita Mintcheva, Valérie Vouret-Craviari, Baharia Mograbi, Maud Wurmser, Damien Ambrosetti, Nathalie Rioux-Leclercq, Pascal Maire and Gilles Pagès
Theranostics 2019; doi:10.7150/thno.27794; in press
[Author manuscript]

Note: This page contains manuscripts that have been accepted by this journal. They haven't been typeset by the journal and the content may change before final publication.